Population-based primary HPV mRNA cervical screening compared with cytology screening.

Abstract:

:Primary HPV screening for cervical cancer by HPV mRNA testing (Aptima) was implemented in January 2017, for women ≥30 through 70 years, in the Region of Skåne, Sweden. HPV positive samples underwent cytology assessment, and women with any degree of abnormal cytology were referred for colposcopy. The aim was to audit the primary HPV screening program, by comparing the cytology results to those of corresponding women (aged ≥30 through 65 years) screened with conventional cytology during 2016. Overall, HPV was detected among 7.0% (4433/63,055) of the women ≥30-70 years in the primary HPV screening program. Among a co-tested (cytology and HPV) subgroup aged 40-42 years (N = 5039), HPV was detected in 100% (28/28) of high-grade squamous intraepithelial lesions (HSIL) and atypical squamous cells of undetermined significance (ASCUS) where HSIL could not be excluded (ASCH) (9/9), and in 80% (4/5) of cases of atypical glandular cells (AGC). Among women ≥30-65 years, the proportion ASCUS or worse (ASCUS+) was similar with cytology (3.52% [2016]) and primary HPV screening (3.70% [2017]). Only the proportion of ASC-H changed by the use of primary HPV screening, from 0.13% (2016) to 0.23% (2017) (p < 0.001). The colposcopy referral rate increased by 54% (3.70 vs 2.41%), when primary HPV screening was introduced. In conclusion, the implemented primary HPV screening approach demonstrated similar prevalence of ASCUS+ cytology as conventional screening. In addition, primary HPV screening decreased cytology assessments by 86% in our screening population of women 30 through 70 years taken into account the co-tested women.

journal_name

Prev Med

journal_title

Preventive medicine

authors

Lindroth Y,Borgfeldt C,Thorn G,Bodelsson G,Forslund O

doi

10.1016/j.ypmed.2019.04.021

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

61-66

eissn

0091-7435

issn

1096-0260

pii

S0091-7435(19)30160-4

journal_volume

124

pub_type

杂志文章
  • How personalized medical data could improve health care.

    abstract::We present a redesign of medical test results by placing the information of blood samples in the context of the patient's personal clinical data. We predict that implementing personalized data in the treatment of patients will promote engagement in the treatment, motivate patients to take responsibility and lead to gr...

    journal_title:Preventive medicine

    pub_type: 信件

    doi:10.1016/j.ypmed.2014.08.008

    authors: Andersson N,Grinberg A,Okkels N

    更新日期:2014-10-01 00:00:00

  • Influenza vaccination in the 2009-2010 pandemic season: the experience of primary care physicians.

    abstract:OBJECTIVES:Determine among a representative sample of pediatricians (Peds), family medicine (FM), and general internal medicine (GIM) physicians in the 2009-2010 influenza season physicians': 1) practices and experiences with delivery of seasonal and pH1N1 influenza vaccines; and 2) anticipated and experienced barriers...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2012.04.014

    authors: O'Leary ST,Stokley S,Crane LA,Allison MA,Hurley LP,Wortley P,Babbel CI,Beaty BL,Gahm C,Kempe A

    更新日期:2012-07-01 00:00:00

  • Use of complementary and alternative medicine among United States adults: the influences of personality, coping strategies, and social support.

    abstract:BACKGROUND:Although patterns of utilization of complementary and alternative medicine (CAM) in the community have begun to be described, few studies have addressed the relationships between dispositional psychological factors and the use of CAM. The aim of this study was to examine the associations between CAM use and ...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2004.05.001

    authors: Honda K,Jacobson JS

    更新日期:2005-01-01 00:00:00

  • Comparing gun-owning vs non-owning households in terms of firearm and non-firearm suicide and suicide attempts.

    abstract::The goal of this study is to provide, for the United States, estimates for gun-owning and non-owning households in terms of firearm and non-firearm suicides and suicide attempts. To make these ballpark estimates I combine a half-dozen known "facts" about suicide (e.g., households with firearms are at approximately 3× ...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2018.12.003

    authors: Hemenway D

    更新日期:2019-02-01 00:00:00

  • Workshop on guidelines to the epidemiology of weak associations. Confounding.

    abstract::The magnitude of confounding is examined in nine case studies of two "weak" relationships: between artificial sweeteners and bladder cancer, and between oral contraceptives and cervical dysplasia. Confounding had little or no influence on the results of any published study. The responsible epidemiologist must always c...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/0091-7435(87)90081-8

    authors: Stellman SD

    更新日期:1987-03-01 00:00:00

  • Predictors of differences in health services utilization for children in Nigerian communities.

    abstract::Health service utilization is an important component of child health promotion. Evidence shows that two-thirds of child deaths in low and middle income countries could be prevented if current interventions were adequately utilized. Aim of this study was to identify determinants of variation in health services utilizat...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2016.12.035

    authors: Adekanmbi VT,Adedokun ST,Taylor-Phillips S,Uthman OA,Clarke A

    更新日期:2017-03-01 00:00:00

  • Financial incentives and weight control.

    abstract::This paper reviews research studies evaluating the use of financial incentives to promote weight control conducted between 1972 and 2010. It provides an overview of behavioral theories pertaining to incentives and describes empirical studies evaluating specific aspects of incentives. Research on financial incentives a...

    journal_title:Preventive medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ypmed.2011.12.024

    authors: Jeffery RW

    更新日期:2012-11-01 00:00:00

  • The cancer information service research consortium: an emerging laboratory for cancer control research.

    abstract::The Cancer Information Service (CIS) was established in 1975 by the National Cancer Institute (NCI) to provide accurate, up-to-date information about cancer to the nation. Although the CIS has in the past served as a venue for cancer communications research, up until very recently the research capacity of the CIS was ...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1006/pmed.1998.0245

    authors: Marcus AC,Morra ME,Bettinghaus E,Crane LA,Cutter G,Davis S,Rimer BK,Thomsen C,Warnecke RB

    更新日期:1998-09-01 00:00:00

  • Implementation of school based physical activity interventions: a systematic review.

    abstract:OBJECTIVE:Implementation science is an emerging area in physical activity (PA) research. We sought to establish the current state of the evidence related to implementation of school-based PA models to explore 1) the relationship between implementation and health outcomes, and 2) factors that influence implementation. ...

    journal_title:Preventive medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ypmed.2014.12.034

    authors: Naylor PJ,Nettlefold L,Race D,Hoy C,Ashe MC,Wharf Higgins J,McKay HA

    更新日期:2015-03-01 00:00:00

  • Objectively measured physical activity, sedentary time and subclinical vascular disease: Cross-sectional study in older British men.

    abstract::Low physical activity (PA) and high levels of sedentary time (ST) are associated with higher cardiovascular disease (CVD) risk among older people. However, their independent contribution and importance of duration of PA and ST bouts remain unclear. We investigated associations between objectively measured PA, ST and n...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2016.05.031

    authors: Parsons TJ,Sartini C,Ellins EA,Halcox JPJ,Smith KE,Ash S,Lennon LT,Wannamethee SG,Lee IM,Whincup PH,Jefferis BJ

    更新日期:2016-08-01 00:00:00

  • Does time pressure create barriers for people to receive preventive health services?

    abstract:OBJECTIVE:Regular use of recommended preventive health services can promote good health and prevent disease. However, individuals may forgo obtaining preventive care when they are busy with competing activities and commitments. This study examined whether time pressure related to work obligations creates barriers to ob...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2015.03.008

    authors: Yao X,Dembe AE,Wickizer T,Lu B

    更新日期:2015-05-01 00:00:00

  • Perceptions of the effect of an impending restaurant smoking ban on dining-out experience.

    abstract:BACKGROUND:The introduction of bans on smoking in restaurants is frequently marred by claims that they will lead to a loss of business. METHODS:A representative sample of 3,019 South Australians age 15+ years were asked questions about dining-out frequency and perceived effects of the ban on their dining-out enjoyment...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1006/pmed.1999.0502

    authors: Wakefield M,Roberts L,Miller C

    更新日期:1999-07-01 00:00:00

  • Systematic differences in validity of self-reported mammography behavior: A problem for intergroup comparisons?

    abstract:BACKGROUND:Prior studies of recall accuracy for screening mammogram behavior have examined relatively homogeneous groups. Data are limited on possible systematic group differences, so we evaluated women's recall accuracy in two separate care systems in one city. Methods. Women 50 to 70 years old with and without screen...

    journal_title:Preventive medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1006/pmed.1999.0575

    authors: Lawrence VA,De Moor C,Glenn ME

    更新日期:1999-12-01 00:00:00

  • Neighborhood safety and green space as predictors of obesity among preschool children from low-income families in New York City.

    abstract:BACKGROUND:Neighborhood safety, green space, walkability, and sociodemographics may influence physical activity and childhood obesity. METHODS:Data on measured height and weight, demographic characteristics, and home ZIP code were collected from year 2004 enrollees in a means-tested preschool program in New York City....

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2013.05.012

    authors: Lovasi GS,Schwartz-Soicher O,Quinn JW,Berger DK,Neckerman KM,Jaslow R,Lee KK,Rundle A

    更新日期:2013-09-01 00:00:00

  • Environmental effects on chromosomes in oncology and radiology department personnel.

    abstract::Long-term, low levels of antineoplastic drugs and ionizing radiation in the work environment may have genotoxic effects on chromosomes in personnel. The effects of ionizing radiation is acknowledged in occupational medicine and therefore various measures have been undertaken to prevent such effects. However, there are...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/0091-7435(92)90056-n

    authors: Milković-Kraus S,Kraus O,Krsnjavi H,Kubelka D

    更新日期:1992-07-01 00:00:00

  • Lung cancer risk among Czech women: a case-control study.

    abstract:BACKGROUND:Few data are available to explain the ongoing increase in lung cancer mortality among Czech women. The study is aimed at examining the role of smoking and known or suspected cofactors. METHODS:Data collected by in-person interviews from 269 female lung cancer cases and 1079 controls were analyzed using unco...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1006/pmed.2001.1002

    authors: Kubík AK,Zatloukal P,Tomásek L,Petruzelka L

    更新日期:2002-04-01 00:00:00

  • The burden of cancer attributable to modifiable risk factors in Canada: Methods overview.

    abstract::Up-to-date estimates of current and projected future cancer burden attributable to various exposures are essential for planning and implementing cancer prevention initiatives. The Canadian Population Attributable Risk of Cancer (ComPARe) study was conducted to: i) estimate the number and proportion of cancers diagnose...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2019.03.007

    authors: Brenner DR,Friedenreich CM,Ruan Y,Poirier AE,Walter SD,King WD,Franco EL,Demers PA,Villeneuve PJ,Grevers X,Nuttall R,Smith LM,Volesky KD,O'Sullivan DE,De P,ComPARe Study Team.

    更新日期:2019-05-01 00:00:00

  • Commuting physical activity and prevalence of metabolic disorders in Poland.

    abstract:OBJECTIVES:The aim of this study was to examine the relationship between walking or cycling to work and prevalence of metabolic syndrome (MetS) and its components. METHODS:Cross-sectional analysis of 6401 randomly selected individuals (3297 men and 3104 women) aged 20-74 years, who participated in the National Multice...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2010.09.003

    authors: Kwaśniewska M,Kaczmarczyk-Chałas K,Pikala M,Broda G,Kozakiewicz K,Pająk A,Tykarski A,Zdrojewski T,Drygas W

    更新日期:2010-12-01 00:00:00

  • Exercise in middle-aged adults: self-efficacy and self-presentational outcomes.

    abstract:BACKGROUND:Whereas self-efficacy expectations have been identified as important determinants of exercise participation patterns, little empirical work that examines efficacy expectations as outcomes of exercise participation or their theoretical relationship to other psychological outcomes associated with exercise has ...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1006/pmed.1995.1053

    authors: McAuley E,Bane SM,Mihalko SL

    更新日期:1995-07-01 00:00:00

  • E-cigarette use and asthma in a multiethnic sample of adolescents.

    abstract::There is minimal evidence from epidemiological studies on how e-cigarette use is related to health indices in adolescence. We hypothesized that e-cigarette use would be associated with asthma, controlling for demographics and cigarette smoking. The hypothesis was tested with cross-sectional data from a statewide sampl...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2017.09.023

    authors: Schweitzer RJ,Wills TA,Tam E,Pagano I,Choi K

    更新日期:2017-12-01 00:00:00

  • Smoking prevalence and correlates among Chinese- and Filipino-American adults: findings from the 2001 California Health Interview Survey.

    abstract:OBJECTIVES:We report prevalence rates and correlates of cigarette smoking among a population-based sample of Chinese- and Filipino-American adults together with rates found in other racial/ethnic groups in California. METHODS:All analyses are based on the 2001 California Health Interview Survey. RESULTS:The proportio...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2005.01.014

    authors: Maxwell AE,Bernaards CA,McCarthy WJ

    更新日期:2005-08-01 00:00:00

  • Social capital, political trust and experience of cannabis smoking: a population-based study in southern Sweden.

    abstract:OBJECTIVE:To investigate whether political mistrust in the Riksdag (the national parliament in Sweden) is an independent characteristic of cannabis smokers, or whether it reflects low confidence in people in general, and therefore low social capital. METHOD:The 2004 public health survey in Skåne is a cross-sectional p...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2008.02.003

    authors: Lindström M

    更新日期:2008-06-01 00:00:00

  • Nutrition, antioxidants, and risk factor profile of nonsmokers, passive smokers and smokers of the Prevention Education Program (PEP) in Nuremberg, Germany.

    abstract:BACKGROUND:An elevated risk for coronary artery disease and lung cancer was reported for smokers and nonsmokers exposed to environmental tobacco smoke. Particularly in nonsmokers, in addition to the adverse effects of tobacco smoke, other factors which are associated with the exposure to environmental tobacco smoke may...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1006/pmed.2002.1024

    authors: Tröbs M,Renner T,Scherer G,Heller WD,Geiss HC,Wolfram G,Haas GM,Schwandt P

    更新日期:2002-06-01 00:00:00

  • Adult obesity management in primary care, 2008-2013.

    abstract::In the U.S., the occurrence of weight counseling in primary care for patients with obesity decreased by 10% between 1995-1996 and 2007-2008. There have been several national recommendations and policies to improve obesity management since 2008. The purpose of this study was to examine the rates of body mass index (BMI...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2017.02.020

    authors: Fitzpatrick SL,Stevens VJ

    更新日期:2017-06-01 00:00:00

  • A multivariate study of determinants of vigorous exercise in a community sample.

    abstract::The purpose of this study was to explore the associations between several social learning theory variables and self-reported vigorous exercise and to consider the implications for exercise promotion. A random sample of adults in San Diego, California, was surveyed by mail. The 2,053 respondents (response rate, 43.4%) ...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/0091-7435(89)90051-0

    authors: Sallis JF,Hovell MF,Hofstetter CR,Faucher P,Elder JP,Blanchard J,Caspersen CJ,Powell KE,Christenson GM

    更新日期:1989-01-01 00:00:00

  • Access to US primary care physicians for new patients concerned about smoking or weight.

    abstract::Tobacco smoking and obesity are leading causes of preventable morbidity and mortality in the US, and primary care physicians are the main source of preventive care. However, it is not known whether access for new patients is affected by an expression of interest in preventive care. In a 2015 audit, we called US primar...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2018.04.031

    authors: Tinkler SE,Sharma RL,Susu-Mago RRH,Pal S,Stano M

    更新日期:2018-08-01 00:00:00

  • Smoking and injuries: an overview.

    abstract:BACKGROUND:Although the disease consequences of cigarette smoking are well documented, smoking may also be associated with increased risk of injury. Our purpose is to provide an overview of this potential association. METHODS:We conducted a literature review. RESULTS:Cigarettes are the leading cause of death from fir...

    journal_title:Preventive medicine

    pub_type: 杂志文章,评审

    doi:10.1006/pmed.1994.1070

    authors: Sacks JJ,Nelson DE

    更新日期:1994-07-01 00:00:00

  • Socioeconomic consequences of the 2004 tsunami: policy implications for natural disaster management.

    abstract:OBJECTIVE:The objective of the study is to assess the socioeconomic status of the households affected by the tsunami of 2004 & to determine the factors associated with the recovery of household economic status. METHODS:The study was conducted in tsunami-affected areas in Malaysia in 2010-2011. A total of 193 household...

    journal_title:Preventive medicine

    pub_type: 杂志文章

    doi:10.1016/j.ypmed.2012.12.024

    authors: Su TT,Saimy BI,Bulgiba AM

    更新日期:2013-01-01 00:00:00

  • Effectiveness of a lifestyle intervention and a structured exercise intervention in older adults.

    abstract:OBJECTIVE:To evaluate the effects of a lifestyle intervention and a structured exercise intervention on physical activity in older adults. METHOD:Participants were randomly assigned to a lifestyle intervention (n=60), including an individualized home-based program supported by phone calls, or to a structured intervent...

    journal_title:Preventive medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ypmed.2008.02.017

    authors: Opdenacker J,Boen F,Coorevits N,Delecluse C

    更新日期:2008-06-01 00:00:00

  • YOUTH: decisions and challenges in designing an osteoporosis prevention intervention for teen girls.

    abstract:BACKGROUND:This paper describes decisions about the experimental design for the Youth, Osteoporosis, and Understanding Total Health Project (YOUTH), a trial designed to test the efficacy of a health plan-based lifestyle intervention for increasing bone mineral density among adolescent women 14 to 16 years of age. METH...

    journal_title:Preventive medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ypmed.2004.04.010

    authors: DeBar LL,Ritenbaugh C,Vuckovic N,Stevens VJ,Aickin M,Elliot D,Moe E,Orwoll E,Ernst D,Irving LM

    更新日期:2004-11-01 00:00:00