Abstract：
:Several randomized trials have demonstrated that HPV-based cervical cancer screening is more effective than cytology-based screening. A pooled analysis of long-term follow-up data from these trials has shown reduced cervical cancer mortality in women screened with HPV compared to cytology. As a consequence, many health systems are currently transitioning to HPV-based screening programs. However, there are several controversies that influence whether and how HPV-based cervical cancer screening is implemented in different settings. Here, we discuss the most important controversies surrounding cervical cancer screening using primary HPV testing in light of published data from clinical trials and large observational studies. Overall, there is strong and uniform evidence for the efficacy of HPV-based screening, and little evidence for the usefulness of adding cytology to primary screening. However, there is currently limited data on optimal triage strategies for HPV-positive women, a critical component of an HPV-based screening program. There will likely be multiple choices for integrated screening programs and implementation may differ depending on risk perception, healthcare funds, assay costs, and available infrastructure, among other factors, in different settings. A particular challenge is the integration of screening and vaccination programs, since increasingly vaccinated populations will have a continuous decrease of cervical cancer risk.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Wentzensen N,Arbyn Mdoi
10.1016/j.ypmed.2016.12.040subject
Has Abstractpub_date
2017-05-01 00:00:00pages
33-35eissn
0091-7435issn
1096-0260pii
S0091-7435(16)30443-1journal_volume
98pub_type
杂志文章abstract：OBJECTIVE:This study aimed to identify cognitive and environmental correlates of daily adolescent breakfast consumption. METHODS:Adolescents (n=1089) aged 12-15 years in schools in Rotterdam, The Netherlands, completed a questionnaire measuring daily breakfast consumption, individual cognitions, and home environmental...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2009.02.009
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVES:Population-referenced total activity counts per day (TAC/d) percentiles provide public health practitioners a standardized measure of physical activity (PA) volume obtained from an accelerometer that can be compared across populations. The purpose of this study was to describe the application of TAC/d popula...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2016.02.019
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVES:To address the question of whether serum cotinine is a better measure of cigarette smoking than self-reported behavior by examining the relation of biochemical, physical examination, and depression assessments to self-reported cigarette consumption and serum cotinine in a population-based sample. METHODS:Se...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1995.1031
更新日期：1995-03-01 00:00:00
abstract：:Tobacco smoking and obesity are leading causes of preventable morbidity and mortality in the US, and primary care physicians are the main source of preventive care. However, it is not known whether access for new patients is affected by an expression of interest in preventive care. In a 2015 audit, we called US primar...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2018.04.031
更新日期：2018-08-01 00:00:00
abstract：:The United States continues to face a public health emergency of opioid-related harm, the effects of which could be dramatically reduced through increased access to the opioid antagonist naloxone. Unfortunately, naloxone is too often unavailable when and where it is most needed, partly due to its continued status as a...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2019.105932
更新日期：2020-01-01 00:00:00
abstract：:A cigarette-smoking questionnaire to examine behavior, attitudes, and beliefs related to cigarette use was administered to children, ages 8-17, in a biracial community. Children who experimented with cigarettes but did not adopt the habit (experimental nonadopters) and children who continued to smoke (adopters) were i...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(85)90026-x
更新日期：1985-01-01 00:00:00
abstract：:Stem cells have been considered for their potential in pharmaceutical research, as well as for stem cell-based therapy for many diseases. Despite the potential for their use, the challenge remains to examine the safety and efficacy of stem cells for their use in therapies. Recently, oxidative stress has been strongly ...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ypmed.2011.11.013
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:To describe recent trends in the prevalence and risk factors of obstetric anal sphincter ruptures during between 1997 and 2007 in Finland. METHOD:We analyzed a population-based register of 514,741 women with singleton vaginal deliveries recorded in the Finnish Medical Birth Register. Primiparous (n=2315) and...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2009.10.005
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:This study evaluated the effects of a school-based dietary intervention program to increase fruit and vegetable consumption among fourth-graders. METHODS:Twenty-eight elementary schools were randomized to an immediate intervention condition or to a delayed intervention control condition. Measures of diet an...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章
doi：10.1006/pmed.1999.0630
更新日期：2000-04-01 00:00:00
abstract：:Tobacco-related health disparities disproportionately affect smokers with major depression (MD). Although tobacco simulation models have been applied to general populations, to date they have not considered populations with a comorbid mental health condition. We developed and calibrated a simulation model of smoking a...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2020.106241
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Women age 50 years and older are in need of multiple preventive health care services. Despite recent improvements in rates of delivery of preventive care services, especially within managed care organizations, substantial numbers of women are still being underscreened. Efforts to improve delivery of preventi...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章
doi：10.1006/pmed.2000.0724
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:To evaluate whether 5 combined healthy lifestyle factors (not smoking, moderate drinking, eating minimum salt-preserved foods, being physically active, and having appropriate body mass index) are associated with reduced risk of cancer. METHODS:Participants were enrolled in the Japan Public Health Center Stud...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2011.11.003
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:The effects and constancy of a worksite physical exercise intervention were examined in relation to the physical fitness, perceived health status, and work ability of female service workers during periods of 1 and 5 years. METHODS:The subjects comprised female home care workers divided into an intervention g...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章
doi：10.1006/pmed.2001.0837
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to investigate the association between self-efficacy, enjoyment, and volitional control with active commuting, as well as to analyze the impact of social support from parents, friends, and teachers with active commuting to school. METHODS:Participants in this cross-sectional study w...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2014.02.019
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:Well-documented challenges have hampered both intervention development and research in teen smoking cessation. Addressing these challenges, the Hutchinson Study of High School Smoking (HS Study), the largest group-randomized trial in adolescent smoking cessation to date, incorporates several design innovation...
journal_title：Preventive medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ypmed.2007.05.018
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Data on smoking cessation and relapse for 6 yers of the Multiple Risk Factor Intervention Trial were evaluated in univariate and multivariate analyses to determine the relationship between variables measured at the beginning of the trial and smoking cessation and relapse for special intervention and usual ca...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章
doi：10.1016/0091-7435(91)90057-b
更新日期：1991-09-01 00:00:00
abstract：INTRODUCTION:The Canadian Physical Activity Levels Among Youth (CANPLAY) study collected pedometer data from eight surveys between 2005 and 2014, making it a unique database of objective population physical activity surveillance. The purpose of this study was to describe secular physical activity trends for 5-19year ol...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2015.12.020
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:The Women's Health Trial (WHT) was a feasibility study for a randomized controlled trial designed to test the hypothesis that a reduction in dietary fat reduces breast cancer incidence among women age 45 to 69. Between 1984 and 1988, 2,064 women participated in its two phases. METHODS:A follow-up study of 5...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0091-7435(92)90027-f
更新日期：1992-05-01 00:00:00
abstract：BACKGROUND:This study presents cancer risk prevalence and screening rates of patients attending general practitioners. Conditions addressed include smoking, skin cancer, Pap smears, clinical breast examinations, and mammography. METHODS:A cross-sectional study of 7,160 patients 18-75 years presenting to 230 general pr...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1994.1021
更新日期：1994-03-01 00:00:00
abstract：:The presence of risk factors for cardiovascular diseases were investigated in 7- and 11-year-old schoolchildren (808 subjects). Data analysis was performed according to sex, age, and country of origin of the father. The following variables were investigated: weight, height, total plasma cholesterol (TCH), high density...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(83)90250-5
更新日期：1983-05-01 00:00:00
abstract：BACKGROUND:Cancer-related health behaviours may be affected by barriers to healthcare seeking and beliefs about cancer. The aim was to assess anticipated barriers to healthcare seeking and beliefs about cancer in a sample of the Danish population and to assess the association with socio-economic position. METHODS:A po...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2014.12.007
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:Diet is an essential part of the nonpharmacological management of hypertension. The aim of this study was to investigate in a primary health care setting the effect of intensified diet counseling on the diet of hypertensive subjects. METHODS:A total of 715 free-living subjects, ages 25-74 years, with systol...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/pmed.2002.1120
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To assess the preferred methods to quit smoking among current smokers. METHOD:Cross-sectional, population-based study conducted in Lausanne between 2003 and 2006 including 988 current smokers. Preference was assessed by questionnaire. Evidence-based (EB) methods were nicotine replacement, bupropion, physicia...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2011.02.005
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:Associations are examined between parental smoking and smoking onset by their children. Smoking parents are more likely to have children who start smoking in their teenage years; however, less is known about whether parental quitting is related to adolescent smoking. METHODS:A cross-sectional national sampl...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2003.11.008
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:Treatment delays in breast cancer are generally thought to affect prognosis but the impact on survival remains unclear. Indicators for breast cancer care include time to primary treatment. The purpose of this study was to evaluate whether time to primary treatment (TPT) in breast cancer impacts survival. MET...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2012.12.001
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to investigate the associations between various modes of transport to work and overweight and obesity, in men and women. METHODS:The study was conducted using data from a representative sample of 6810 respondents who reported being in the workforce, extracted from the 2003 New South...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2007.08.009
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to investigate the prevalence and identify factors associated with simultaneous risk behaviors for chronic noncommunicable diseases in adults in a southern capital in Brazil. METHOD:A cross-sectional, population-based study was carried out with 1720 adults in Florianópolis, Braz...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2012.10.022
更新日期：2013-01-01 00:00:00
abstract：:This report evaluates the effectiveness of various measures to control the size of illicit cigarette trade in Kenya. It is based on a literature review, a review of conference proceedings/materials, online searches, and analyses of data from the National Statistical Office of Kenya, ERC, and Euromonitor. I used both p...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2017.04.025
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVES:To estimate the prevalence of smoking and exposure to secondhand smoke among asthmatic Missourians and to describe associated predisposing factors. METHOD:The Missouri County-level Behavioral Risk Factor Survey, conducted among 15,059 non-institutionalized Missourians aged 18 years or older using random-dig...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2006.01.004
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:Despite the burden of colorectal cancer and improved health care outcomes with early detection and treatment, screening rates among eligible adults are low. We previously developed through a series of studies an interactive electronic tool, Colorectal Web, to promote colorectal cancer screening. METHOD:From ...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ypmed.2007.07.003
更新日期：2007-10-01 00:00:00
