Abstract：
:Stem cells have been considered for their potential in pharmaceutical research, as well as for stem cell-based therapy for many diseases. Despite the potential for their use, the challenge remains to examine the safety and efficacy of stem cells for their use in therapies. Recently, oxidative stress has been strongly implicated in the functional regulation of cell behavior of stem cells. Therefore, development of rapid and sensitive biomarkers, related to oxidative stress is of growing importance in stem cell-based therapies for treating various diseases. Since stem cells have been implicated as targets for carcinogenesis and might be the origin of "cancer stem cells", understanding of how oxidative stress-induced signaling, known to be involved in the carcinogenic process could lead to potential screening of cancer chemopreventive and chemotherapeutic agents. An evaluation of antioxidant states reducing equivalents like GSH and superoxide dismutase (SOD), as well as reactive oxygen species (ROS) and nitric oxide (NO) generation, can be effective markers in stem cell-based therapies. In addition, oxidative adducts, such as 4-hydroxynonenal, can be reliable markers to detect cellular changes during self-renewal and differentiation of stem cells. This review highlights the biomarker development to monitor oxidative stress response for stem cell-based chemical screening.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Yang SR,Rahman I,Trosko JE,Kang KSdoi
10.1016/j.ypmed.2011.11.013subject
Has Abstractpub_date
2012-05-01 00:00:00pages
S42-9eissn
0091-7435issn
1096-0260pii
S0091-7435(11)00476-2journal_volume
54 Supplpub_type
杂志文章,评审abstract：:A key element in most efforts to prevent disease and promote health is behavioral change to lower risk. One-to-one programs to help people change their behavior are seriously limited because of the difficulty people have in making behavioral changes and because one-to-one programs do little to modify those forces in t...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(86)90026-5
更新日期：1986-09-01 00:00:00
abstract：BACKGROUND:Early detection of skin cancer is associated with improved prognosis. The American Cancer Society's current skin cancer screening (SCS) recommendation states that adults over the age of 40 should receive an annual skin examination conducted by a health professional. However, little is known about the psychos...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.01.017
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:This article describes the results of studies on the barriers and benefits of cervical cancer screening from the perspective of women, men, and health providers in five Latin American countries and compares them to other findings from the literature. METHODS:Five separate qualitative studies (focus groups a...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.03.040
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVE:To establish the efficacy of an internet based prevention program to reduce alcohol and cannabis use in adolescents. METHOD:A cluster randomised controlled trial was conducted with 764 13-year olds from ten Australian secondary schools in 2007-2008. Half the schools were randomly allocated to the computerise...
journal_title：Preventive medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ypmed.2009.04.009
更新日期：2009-06-01 00:00:00
abstract：:Ernst Wynder did not believe that environmental tobacco smoke (ETS), also known as secondhand smoke, was a cause of lung cancer because his own data did not support this. His view on the issue may have begun to change with our initial studies, carried out at the American Health Foundation, showing that metabolites of ...
journal_title：Preventive medicine
pub_type： 传,历史文章,杂志文章
doi：10.1016/j.ypmed.2006.07.020
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Participant recruitment is an understudied part of health research. It can be a limiting factor and can affect the external validity of a study. This study compares two recruitment methods, active and passive, used to recruit university seniors into a health promotion study. METHODS:During active recruitmen...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1998.0327
更新日期：1998-07-01 00:00:00
abstract：:Using X-ray fluorescence spectrometry, 11 heavy elements at concentrations that are easily detectable have been identified in smokeless tobacco products. These concentrations were found to increase in cheek epithelium samples of the user after exposure to smokeless tobacco. This feasibility study suggests that the lev...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(88)90048-5
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE:To determine the association between self-reported diabetes and posttraumatic stress disorder (PTSD) among adults in the community and to investigate the specificity of this link. METHOD:Data were drawn from the National Comorbidity Survey (NCS), a household probability sample of adults ages 15-54 in the Uni...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.07.013
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:This paper estimates the rates of lifetime nonreceipt of influenza immunization among elderly and examines variations in the lifetime nonreceipt of immunization by gender, race and ethnic group, socioeconomic status, access to health care, and health status. METHODS:Cross-sectional, nationally representative...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.07.017
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Despite the importance of breast cancer screening to reduce morbidity and mortality, limited information is available on screening practices among African American women with a family history that is suggestive of hereditary breast cancer. OBJECTIVES:To describe adherence to breast cancer screening recommen...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2006.06.003
更新日期：2006-11-01 00:00:00
abstract：:The dramatic increase in youth use of electronic nicotine delivery systems (ENDS; e.g., e-cigarettes) in the United States has focused regulatory efforts to address this concern while still encouraging smokers to switch completely to lower risk products or quit all tobacco product use. Increases in the minimum age for...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2020.106145
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:To review the empirical evidence concerning the strength of tracking of sedentary behaviours from childhood and adolescence. METHODS:Published English language studies were located from computerised and manual searches in 2009. Included studies were prospective, longitudinal studies with at least one sedenta...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ypmed.2010.07.018
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:: Little is known of the preventive effects of physical activity in leisure time on neck and upper limb symptoms. METHODS:: A cohort of 1742 employees was selected from a prospective cohort study with a follow-up period of 3 years. Independent variables were sporting activities and physically active commuti...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.11.006
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Physical activity has been shown to attenuate the association between overweight/obesity and mortality. Much less is known, however, on how the duration of overweight/obesity potentially alters this association, which was the purpose of this study. METHODS:The 1999-2006 NHANES was used and 11,057 adults (ag...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2015.12.002
更新日期：2016-02-01 00:00:00
abstract：:In 1960 the meat-consumption habits of 25,153 California Seventh-Day Adventists were assessed by questionnaire. Between 1960 and 1980 ischemic heart disease deaths were identified. Meat consumption was positively associated with fatal ischemic heart disease in both men and women. This association was apparently not du...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(84)90017-3
更新日期：1984-09-01 00:00:00
abstract：:This study explored youths' experiences and perceptions about community engagement as a result of participating in a community-based data collection project using paper and mobile technology park environmental audit tools. In July 2014, youth (ages 11-18, n=50) were recruited to participate in nine focus groups after ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2016.08.043
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:The Institute of Medicine recommends that public health agencies restrict the number and regulate the location of tobacco retailers as a means of reducing tobacco use. However, the best policy strategy for tobacco retailer reduction is unknown. PURPOSE:The purpose of this study is to test the percent reduct...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2015.01.025
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:There is evidence linking the built environment (BE) with physical activity (PA), but few studies have been conducted in Latin America (LA). State-of-the-art methods and protocols have been designed in and applied in high-income countries (HIC). In this paper, we identify key challenges and potential solution...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2014.10.014
更新日期：2014-12-01 00:00:00
abstract：:The Cancer Prevention and Control Research Network (CPCRN) is one of the thematic networks of the United States' Centers for Disease Control and Prevention's (CDC) Prevention Research Centers. Network members are academic research centers in the United States who collaborate with public health and community partners t...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2019.105824
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVES:In the absence of raised intraocular pressure (IOP), haemodynamic parameters have been implicated in the development of normal tension glaucoma (NTG). The purpose of this study is to compare 24-hour IOP and haemodynamic parameters in NTG patients and non-glaucoma patients. METHODS:This is a cross sectional ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2013.01.007
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Prior studies of recall accuracy for screening mammogram behavior have examined relatively homogeneous groups. Data are limited on possible systematic group differences, so we evaluated women's recall accuracy in two separate care systems in one city. Methods. Women 50 to 70 years old with and without screen...
journal_title：Preventive medicine
pub_type： 杂志文章,多中心研究
doi：10.1006/pmed.1999.0575
更新日期：1999-12-01 00:00:00
abstract：:Ethnic groups in the United States exhibit different patterns of cardiovascular disease and cancer morbidity and mortality. This has, in part, been attributed to differences in dietary intake. However, there is limited comparative information available regarding the dietary patterns of whites, blacks, and Hispanics re...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(88)90055-2
更新日期：1988-09-01 00:00:00
abstract：:Immunization programs have been challenged by vaccine crises. Between 2013 and 2018, China has experienced three major vaccine scandals and crises, which has partly impaired Chinese public trust in domestically produced vaccines. This study aims to explore the associations between parental trust toward CDC-released cr...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2021.106423
更新日期：2021-01-10 00:00:00
abstract：:The encouragement of human papillomavirus (HPV) vaccination is an important goal for interventions among American Indians (AIs), given the significant disparities AIs face with respect to HPV cancers. Tailoring intervention messages to the culture of message recipients has been proposed as a potentially useful interve...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2018.08.021
更新日期：2018-10-01 00:00:00
abstract：:It appears that most people who engage in exercise for 20-60 min per day, 3 days per week, at an intensity level of 70-80% of maximal heart rate will derive at least some health-related benefits associated with improved cardiorespiratory fitness and optimal body weight. Individuals exhibiting extremely low cardiorespi...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1016/0091-7435(84)90042-2
更新日期：1984-01-01 00:00:00
abstract：BACKGROUND:Neighborhood safety, green space, walkability, and sociodemographics may influence physical activity and childhood obesity. METHODS:Data on measured height and weight, demographic characteristics, and home ZIP code were collected from year 2004 enrollees in a means-tested preschool program in New York City....
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2013.05.012
更新日期：2013-09-01 00:00:00
abstract：:The prevalence of eight adverse lifestyle risk factors which are linked to increased morbidity and mortality was determined. Smoking, excess alcohol use, obesity, lack of exercise, lack of seatbelt use, use of hazardous transportation vehicles, and inadequate rest were studied. A random sample of 147 patients from a p...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(90)90051-k
更新日期：1990-09-01 00:00:00
abstract：OBJECTIVE:To examine the viability of monetary incentives to increase fitness-center use and maintain/improve the Body Mass Indexes (BMIs) of first-year students over the fall semester. METHOD:Randomized-controlled trial with no-treatment and incentive conditions involving 117 first-year students. For 12 weeks, studen...
journal_title：Preventive medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ypmed.2012.12.020
更新日期：2013-03-01 00:00:00
abstract：:Some questions about adolescent smoking levels as reported in national surveys were recently raised by M. B. Mittelmark, D. M. Murray, R. N. Luepker, and T. F. Pechacek, [Prev. Med. 11, 708-712 (1982)]: such levels may be underreported, calling into question the decline in adolescent smoking. The present article sugge...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(84)90033-1
更新日期：1984-07-01 00:00:00
abstract：:The Community Care Connections (CCC) program aims to align social and healthcare services to improve health outcomes in older adults with complex medical and social needs. This study assessed changes in healthcare utilization before and after CCC program participation. Between June 2016 and March 2019, 1214 adults wit...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2020.106350
更新日期：2021-02-01 00:00:00
