Abstract:
:Ernst Wynder did not believe that environmental tobacco smoke (ETS), also known as secondhand smoke, was a cause of lung cancer because his own data did not support this. His view on the issue may have begun to change with our initial studies, carried out at the American Health Foundation, showing that metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) were present in the urine of non-smokers exposed to ETS. The metabolites - 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its glucuronides (NNAL-Glucs) - have now emerged as leading biomarkers for the study of carcinogen exposure in non-smokers exposed to ETS. Subsequent work has consistently demonstrated elevated levels of NNAL plus NNAL-Glucs in the urine of people exposed to ETS in various field studies and throughout life. These studies strongly support the epidemiologic data demonstrating that ETS exposure causes lung cancer in non-smokers and have likely had an impact on tobacco control.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Hecht SSdoi
10.1016/j.ypmed.2006.07.020subject
Has Abstractpub_date
2006-10-01 00:00:00pages
256-60issue
4eissn
0091-7435issn
1096-0260pii
S0091-7435(06)00326-4journal_volume
43pub_type
传,历史文章,杂志文章abstract:OBJECTIVES:The aim of this study was to examine the relationship between walking or cycling to work and prevalence of metabolic syndrome (MetS) and its components. METHODS:Cross-sectional analysis of 6401 randomly selected individuals (3297 men and 3104 women) aged 20-74 years, who participated in the National Multice...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2010.09.003
更新日期:2010-12-01 00:00:00
abstract::During the last 25 years a remarkable change has occurred in the ranking of the causes of death in Japan. In particular, stroke, the leading cause of death in Japan for a long period of time, has been declining from its peak in 1965. Although ischemic heart disease increased about fourfold, it is not yet as prominent ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(83)90198-6
更新日期:1983-01-01 00:00:00
abstract::There is an urgent need to find novel strategies aimed at motivating people to go outside and move more. Pokémon Go blends a fun smartphone game with real-life, outdoor physical activity. Initial reports suggest it is a successful population level strategy to increase physical activity levels. Further research is need...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.11.012
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Obesity is a significant problem among US veterans. Diets high in fruits and vegetables (FV) can lower obesity risk. Health communication interventions are promising strategies for promoting healthy eating. We evaluated whether an enhanced intervention with tailored newsletters and motivational interviewing ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2010.06.010
更新日期:2010-09-01 00:00:00
abstract::Within a quarter century the convergence of geographical and prospective epidemiology, clinical research, and laboratory investigation has provided strongly attested theories of coronary heart disease (CHD) etiology. Evidence that application of these theories will reduce CHD incidence is incomplete but adequate to ju...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(83)90189-5
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Initiation of sun protection strategies can be promoted, to some extent, by educational efforts, but little is known about the merit of continuing education interventions in sustaining the desired behaviors or adding new behaviors. This prospective study clarifies the choices individuals make among the four ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(92)90082-s
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:To assess Pap smear utilization and compliance with screening recommendations, a study was conducted in a large midwestern HMO where cost is not a barrier to care. The purpose of the study was to examine rates of screening by age, identify the proportion of abnormal cytologic findings, and determine screenin...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1996.0041
更新日期:1996-03-01 00:00:00
abstract::This study explored youths' experiences and perceptions about community engagement as a result of participating in a community-based data collection project using paper and mobile technology park environmental audit tools. In July 2014, youth (ages 11-18, n=50) were recruited to participate in nine focus groups after ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.08.043
更新日期:2017-02-01 00:00:00
abstract::Despite tremendous gains in our understanding of the development of memory during the infancy period, relatively little is known about the neural bases of early memory. This is unfortunate, as elucidating the neurobiological mechanisms that mediate changes in memory would likely yield important insight into the concep...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1006/pmed.1998.0272
更新日期:1998-03-01 00:00:00
abstract::Extracurricular sport has been a valued educational investment to promote both physical and mental health in children and adolescents. Few longitudinal studies have tested whether extracurricular sport is associated with inattentive/hyperactive symptoms. Using a prospective-longitudinal birth cohort of 758 girls and 7...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2020.106256
更新日期:2020-12-01 00:00:00
abstract::This investigation examined the relationship between lifestyle, as defined by common health habits, and symptoms of depression in a general community sample. The study was conducted using data from a longitudinal survey involving four interviews of 1,003 Los Angeles County adults. The survey focused on the epidemiolog...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(88)90061-8
更新日期:1988-03-01 00:00:00
abstract::In the Amsterdam Growth and Health Longitudinal Study (AGAHLS) biological risk factors for chronic diseases were measured on eight separate occasions over a period of 20 years in a group of apparently healthy males and females (n = 164). Data were first collected from participants at 13 years of age. At each of the ei...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2002.1107
更新日期:2002-12-01 00:00:00
abstract::To determine serum lipid levels and their correlates in one of the world's most isolated populations, 62 adult Yanomamo Indians from the Amazonian rain forest were examined. After measurement of body weight and height, and estimation of age, casual blood samples were obtained. Estimated age ranged from 20 to 68 years,...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(90)90009-9
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:We investigated associations of walking and other leisure-time physical activity (LTPA) with environmental characteristics and transportation modes in older Japanese adults. METHODS:This cross-sectional study in 2010-2011 used data from 421 community-dwelling older adults aged 65-85 years living in Kasama Ci...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.05.013
更新日期:2012-08-01 00:00:00
abstract::Physical activity guidelines for cancer survivors issued by the American Cancer Society and the American College of Sports Medicine emphasize the essential role of a health care provider (HCP) in counseling cancer survivors to achieve healthier lifestyles. However, research has not established whether HCP's recommenda...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.01.010
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:Accelerometers are being increasingly used in studies of physical activity (PA) among older adults, however the use of these monitors requires some specialized knowledge and up-to-date information on technological innovations. The purpose of this review article is to provide researchers with a guide to some c...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ypmed.2008.12.001
更新日期:2009-02-01 00:00:00
abstract::There is increasing interest in biofeedback and self-regulatory approaches to health enhancement. The movement has not gone unnoticed by business and industry. At this point, there are adequate data to demonstrate the effectiveness of different forms of stress management intervention. Using the experience of the Equit...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(83)90222-0
更新日期:1983-09-01 00:00:00
abstract:INTRODUCTION:Interventions targeting children's dietary behavior often include strategies that target parents as implementation agents of change, though parent involvement on intervention effectiveness is unclear. The present study systematically assessed (1) reporting of reach, effectiveness, adoption, implementation ...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ypmed.2016.08.030
更新日期:2016-10-01 00:00:00
abstract::Chronic kidney disease (CKD) affects 15% of the US general population, and this rate is projected to increase. A healthy lifestyle is important for individuals with CKD to reduce risk for CKD progression and adverse heath events. Adults with CKD also have high rates of psychological distress, which may be associated w...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2019.06.007
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:It is proposed that, historically, when the conditions are right for laboratory sciences to contribute to causal knowledge, they take the place of epidemiology as leaders in a given field. METHODS:Review examples of cholera, pellagra, and Kaposi's sarcoma. RESULTS:In the cases of cholera, pellagra, and Kap...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ypmed.2011.07.018
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to assess public support for a smoking cessation policy involving financial incentives. METHODS:We conducted a randomized controlled trial using an experimental survey design. One of four questionnaire versions was distributed to participants. Each version described a smoking cessati...
journal_title:Preventive medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ypmed.2012.06.013
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:This paper assesses the potential benefits of increased walking and reduced obesity associated with taking public transit in terms of dollars of medical costs saved and disability avoided. METHODS:I conduct a new analysis of a nationally representative U.S. transportation survey to gauge the net increase in ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2007.10.004
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:To investigate the psychometric properties of the developed 21 item questionnaire to measure definitions, attitudes and management practices in relation to diarrhea during enteral nutrition (DAPonDEN). METHODS:Data were analyzed using exploratory factor analysis from a cross sectional study of 102 nurses ag...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.12.021
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:This study explores the predisposing, enabling, and need-based factors associated with parents' or guardians' decision to have their child initiate, continue, and complete the human papillomavirus (HPV) vaccine. METHODS:Parents and guardians of children between the ages of 9 and 17years who completed the 20...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.01.010
更新日期:2016-04-01 00:00:00
abstract::Some cancer survivors report spending 20% of their annual income on medical care. Undue financial burden that patients face related to the cost of care is referred to as financial hardship, which may be more prevalent among rural cancer survivors. This study examined contrasts in financial hardship among 1419 rural an...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2019.105881
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Research has shown that social images or prototypes of smoking peers play a role in adolescents' decisions to start smoking. To devise effective prevention measures, specific information is needed about how adolescents evaluate characteristics associated with smoker prototypes. Such evaluation is assumed to ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2004.09.025
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Recent studies find lesbians at greater risk for overweight and obesity than heterosexual women. While this may reflect differences in attitudes concerning weight and body shape, little is actually known about risk factors within this group. This study examines correlates of obesity and exercise frequency am...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/s0091-7435(03)00020-3
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:To describe the prevalence of mammography use, and to estimate its association with sociodemographics. METHODS:A sample of 6207 women aged 60 and older from the first interview of Health, Well-Being and Aging in Latin America and the Caribbean Study (SABE) in seven cities (Buenos Aires, Bridgetown, Havana, ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2006.02.005
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:In the fall of 1986 the North Karelia Project in cooperation with Finnish TV 2 arranged an eight-part nationwide smoking cessation TV program. The Project, also arranged a smoking cessation contest coinciding with the TV program in cooperation with four major voluntary public health organizations and the nat...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(92)90007-5
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Elevated total homocysteine (tHcy) levels (>/= 15 micromol/L), resulting from enzyme or vitamin deficiency, increase risk for cardiac, cerebral, and peripheral vascular disease. This study examines tHcy levels in an Israeli population and the relationship to vitamin status and disease. The need for screening...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2003.09.001
更新日期:2003-12-01 00:00:00