Until the lab takes it away from epidemiology.

Abstract:

BACKGROUND:It is proposed that, historically, when the conditions are right for laboratory sciences to contribute to causal knowledge, they take the place of epidemiology as leaders in a given field. METHODS:Review examples of cholera, pellagra, and Kaposi's sarcoma. RESULTS:In the cases of cholera, pellagra, and Kaposi's sarcoma, epidemiology ceased to be at the forefront of knowledge acquisition when laboratory sciences identified more proximate causes than those that epidemiologic group comparisons could reveal. CONCLUSION:These three examples deal with diseases, which, at the individual level, appear to rely predominantly on a single factor. For diseases whose causes still elude specific identification by the laboratory sciences, epidemiology may be uniquely equipped to play a leading role.

journal_name

Prev Med

journal_title

Preventive medicine

authors

Morabia A

doi

10.1016/j.ypmed.2011.07.018

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

217-20

issue

4-5

eissn

0091-7435

issn

1096-0260

pii

S0091-7435(11)00284-2

journal_volume

53

pub_type

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