Abstract:
:The aim of the present study was to determine the ferulic acid (FA) content of Radix Angelicae Sinensis (AS), Danggui-Buxue-Tang (DBT) and Danggui-Sini-Tang (DST) using the same ultra performance liquid chromatography system and method. FA was eluted using an Acquity BEH C18 column (100×2.1 mm inner diameter; 1.7 μm). A mobile phase of methanol and 0.5% acetic acid was used and a flow rate of 0.3 ml/min was selected. The calibration curve exhibited a good linear regression (R2=0.9997). The inter- and intra-day precision measurements of FA ranged between 0.27 and 3.03% and the recovery ranged between 98.44 and 101.64% with relative standard deviation (RSD) values ≤4.73%. The method was reliable and simple. The results of the chromatographic analyses indicate that the FA contents of the DBT and DST decoctions were increased compared with that of AS due to the presence of other herbs.
journal_name
Exp Ther Medjournal_title
Experimental and therapeutic medicineauthors
Yao JM,Yu LJ,Chen Q,Chen ZQ,Wang DS,Qiu XJ,Zhao LLdoi
10.3892/etm.2014.1547subject
Has Abstractpub_date
2014-05-01 00:00:00pages
1364-1368issue
5eissn
1792-0981issn
1792-1015pii
etm-07-05-1364journal_volume
7pub_type
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