Advanced oxidation protein products from the follicular microenvironment and their role in infertile women with endometriosis.

abstract：:The current study mainly evaluated the plasma level of microRNA (miR)-136 in knee osteoarthritis (KOA) patients and determined if miR-136 could be used as a potential biomarker to screen KOA patients from healthy controls. It was demonstrated that plasma miR-136 was significantly decreased in the plasma of KOA patient...

journal_title：Experimental and therapeutic medicine

authors： Wan L,Zhao Q,Niu G,Xiang T,Ding C,Wang S

更新日期：2018-10-01 00:00:00

abstract：:One of the critical factors for predicting the success of percutaneous catheter drainage (PCD) is the mean CT density of collection. A higher CT density suggests more necrotic solid tissue within the collection. In the present study, a novel technique for PCD of the necrotic pancreatic collection with a higher mean CT...

journal_title：Experimental and therapeutic medicine

authors： Gupta P,Koshi S,Samanta J,Mandavdhare H,Sharma V,K Sinha S,Dutta U,Kochhar R

更新日期：2020-09-01 00:00:00

abstract：:Esophageal submucosal tumors are occasionally detected incidentally during a gastrointestinal survey. In the present study, a case of esophageal leiomyoma is reported, which was incidentally detected by chest radiography during an annual survey of mass-screening for lung cancer. The patient underwent a laparoscopic lo...

journal_title：Experimental and therapeutic medicine

authors： Tadano S,Kondo T,Watanabe M,Takayashiki N,Shiozawa T,Ohara G,Kagohashi K,Kurishima K,Satoh H

更新日期：2014-12-01 00:00:00

abstract：:The aim of this study was to systematically search literature and conduct a meta-analysis comparing the clinical efficacy and safety of Evolut R and Sapien 3 valves for transcatheter aortic valve implantation (TAVI). The PubMed, Biomed Central, Scopus, Cochrane library and Google scholar databases were searched for ar...

journal_title：Experimental and therapeutic medicine

authors： He C,Xiao L,Liu J

更新日期：2019-11-01 00:00:00

abstract：:The present study aimed to evaluate the safety and efficiency of ciliary sulcus implantation of intraocular lens (IOL) in patients that had undergone manual small incision cataract surgery (MSICS) complicated by large posterior capsule rupture (LPCR). A total of 11 eyes taken from 11 patients in Brazzaville, Republic ...

journal_title：Experimental and therapeutic medicine

authors： Zhao J,Yu J,Wang T,Mban B

更新日期：2019-02-01 00:00:00

abstract：:Hericium erinaceus (HEP) is a notable medicinal fungus grown in China and other oriental countries. Polysaccharides from HEP have recently attracted considerable attention due to their numerous physiological activities. The objective of this study was to evaluate the anti-fatigue activity of HEP in a mouse model. Afte...

journal_title：Experimental and therapeutic medicine

authors： Liu J,DU C,Wang Y,Yu Z

更新日期：2015-02-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy and safety of polyethylene glycol 4000 (PEG 4000) for the treatment of constipation in children over 8 years of age. A total of 216 children from 7 hospitals were enrolled. A total of 105 patients received oral PEG 4000 (20 g/day) and 111 patients received oral lactul...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Wang B,Jiang X,Jiang M,Xu C,Shao C,Jia L,Huang Z,Xu X,Liu H,Shang L

更新日期：2012-05-01 00:00:00

abstract：:In the present study, we analyzed schizophrenia (SCZ)-related genome-wide association studies (GWAS) to identify genes and pathways associated with SCZ. We identified 1,098 common genes (1,098/9,468) and 20 shared KEGG pathways (both P<0.01) by integrating candidate genes from the European and American SCZ-related GWA...

journal_title：Experimental and therapeutic medicine

authors： Wang Z,Li P,Wu T,Zhu S,Deng L,Cui G

更新日期：2018-12-01 00:00:00

abstract：:The present study aimed to analyze the imaging, clinical and pathological features of fungal infection involvement in primary biliary cirrhosis (PBC) by retrospectively analyzing and reviewing the features of two patients with fungal infection involvement in PBC. Both patients were female. One patient had a confirmed ...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Zhao Z,Lu H,Zhang J,Huang F

更新日期：2017-02-01 00:00:00

abstract：:Red cell distribution width (RDW) has been found to be a novel prognostic biomarker in patients with coronary artery disease (CAD); however, the association between RDW and the risk of heart events in patients with CAD is yet to be fully elucidated. Thus, the aim of the present study was to determine whether an elevat...

journal_title：Experimental and therapeutic medicine

authors： Li W,Li X,Wang M,Ge X,Li F,Huang B,Peng J,Li G,Lu L,Yu Z,Ma J,Xu L,Jin M,Si H,Wan R

更新日期：2015-04-01 00:00:00

abstract：:Peripheral nerve predegeneration has been used as a tool to improve the in vitro cultivation of Schwann cells. The process of predegeneration may be accomplished either in vivo or in vitro. In previously published studies, various predegeneration periods were used, ranging from a few days until up to 5 weeks. The pres...

journal_title：Experimental and therapeutic medicine

authors： Tomko P,Slovinská L,Vanický I

更新日期：2019-01-01 00:00:00

abstract：:The anticancer properties of epigallocatechin-3-gallate (EGCG) are documented in the treatment of several types of cancer; however, there is no relevant evidence for its efficacy in the treatment of renal cell carcinoma (RCC). In the present study, the therapeutic effects of EGCG in vitro were investigated, with parti...

journal_title：Experimental and therapeutic medicine

authors： Chen SJ,Yao XD,Peng BO,Xu YF,Wang GC,Huang J,Liu M,Zheng JH

更新日期：2016-04-01 00:00:00

abstract：:The present study investigated the efficacy and safety of digital subtraction angiography-guided 3% polidocanol foam sclerosing agent, as well as the combination of pingyangmycin and dexamethasone, for the treatment of children with oropharyngeal low-flow venous malformation. A total of 27 children with 35 lesions wit...

journal_title：Experimental and therapeutic medicine

authors： Song D,Guo L,Sheng H,Li J,Wang L,Wu C,Wang C,Niu Y,Zeng Q

更新日期：2020-05-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate the expression of targeted genes in a post-transcriptional manner. Increasing evidence indicates that miRNAs play important roles in cancer pathogenesis, including apoptosis, proliferation and differentiation, as oncogenes or tumor suppressors. Previo...

journal_title：Experimental and therapeutic medicine

authors： Shen ZY,Zhang ZZ,Liu H,Zhao EH,Cao H

更新日期：2014-06-01 00:00:00

abstract：:Mutations in keratin 5 (KRT5) or KRT14 genes are responsible for the most severe form of epidermolysis bullosa simplex (EBS), which is EBS generalized severe (EBS-gen sev). To date, only four pathogenic mutations (p.Arg165Ser and p.Lys199Asn in KRT5; p.Arg125Cys and p.Arg125His in KRT14) have been reported to be respo...

journal_title：Experimental and therapeutic medicine

authors： Zhang J,Yan M,Liang J,Li M,Yao Z

更新日期：2016-11-01 00:00:00

abstract：:Diabetic keratopathy is an ocular complication that occurs with diabetes. In the present study, the effect of diabetic keratopathy on corneal optical density, central corneal thickness, and corneal endothelial cell count was investigated. One hundred and eighty diabetic patients (360 eyes) were enrolled in the study d...

journal_title：Experimental and therapeutic medicine

authors： Gao F,Lin T,Pan Y

更新日期：2016-09-01 00:00:00

abstract：:Lung adenocarcinoma (LACA) is the leading cause of cancer-associated death worldwide. The present study intended to identify DNA methylation patterns that may serve as diagnostic and prognostic biomarkers for LACA. Data on DNA methylation and the survival data of the patients of LACA were obtained from The Cancer Geno...

journal_title：Experimental and therapeutic medicine

authors： Zheng R,Xu H,Mao W,Du Z,Wang M,Hu M,Gu X

更新日期：2020-01-01 00:00:00

abstract：:The present study investigated the characteristic features of cancer stem cells (CSCs) using an aggressive human osteosarcoma cell line OS-65. Hoechst 33342 dye exclusion was used to distinguish the cancer stem-like side population (SP) cells from OS-65 cells. Furthermore, the SP cells were characterized via chemoresi...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Teng JS

更新日期：2016-07-01 00:00:00

abstract：:Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics TEN, while no purule...

journal_title：Experimental and therapeutic medicine

authors： Liu LF,Yan JL,Wang JY,Chen JS,Cai SQ,Lao LM,Zheng M

更新日期：2013-04-01 00:00:00

abstract：:Osteonecrosis is a condition that frequently affects patients with systemic lupus erythematosus (SLE). However, reports on severe multifocal osteonecrosis involving more than three anatomical sites in patients with SLE are scarce. The present study describes a case of SLE with multifocal osteonecrosis involving all fo...

journal_title：Experimental and therapeutic medicine

authors： Sun S,Wang Q,Gong Y,Qi X,Liu J

更新日期：2019-10-01 00:00:00

abstract：:Somatostatin has been extensively studied for the prophylaxis of pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP). However, the results remain controversial. The present retrospective cohort study aimed to investigate the efficacy of pre- and post-ERCP somatostatin administration in the pre...

journal_title：Experimental and therapeutic medicine

authors： Zhao LN,Yu T,Li CQ,Lai Y,Chen QK

更新日期：2014-08-01 00:00:00

abstract：:The US Food and Drug Administration approved thalidomide and its analogues for the treatment of erythema nodosum leprosum, in spite of the notoriety of reports of severe birth defects in the middle of the last century. As immunomodulatory drugs, thalidomide and its analogues have been used to effectively treat various...

journal_title：Experimental and therapeutic medicine

authors： Liu T,Guo F,Zhu X,He X,Xie L

更新日期：2017-12-01 00:00:00

abstract：:The aim of this study was to investigate the effect of montelukast on the expression of CD4+CD25+ regulatory T cells in children with acute bronchial asthma. Fifty-six child patients with acute bronchial asthma treated in the Department of Pneumology at the Shangluo Central Hospital were selected and randomly divided ...

journal_title：Experimental and therapeutic medicine

authors： Qu X,Chen Y,Yin C

更新日期：2018-09-01 00:00:00

abstract：:In the present study, we demonstrate that the degeneration of intervertebral discs is caused by ageing and apoptosis of matrix cells. Apoptosis is as essential as the function of proteoglycan synthesis in assessing the possible degeneration of intervertebral discs; paeoniflorin (PF) induces cytoprotective effects on v...

journal_title：Experimental and therapeutic medicine

authors： Chen SQ,Lin JP,Zheng QK,Chen SJ,Li M,Lin XZ,Wang SZ

更新日期：2015-12-01 00:00:00

abstract：:Indoleamine 2,3-dioxygenase (IDO) is an immunoregulatory enzyme. It plays a key role in various malignancies, infection and autoimmune diseases. IDO induces immunosuppression through the depletion of tryptophan and its downstream metabolites. Hepatitis C virus (HCV) has infected more than 12 million individuals in Pak...

journal_title：Experimental and therapeutic medicine

authors： Asghar K,Ashiq MT,Zulfiqar B,Mahroo A,Nasir K,Murad S

更新日期：2015-03-01 00:00:00

abstract：:The current study aimed to assess the repeatability and validity of cervical range of motion (CROM) measurements using an optical motion capture system (OMCS), compared with a CROM device. A total of 20 healthy volunteers were selected and enrolled in the current study after informed consent was received. The motion o...

journal_title：Experimental and therapeutic medicine

authors： Feng M,Liang L,Sun W,Liu GW,Yin X,Han T,Wei X,Zhu L

更新日期：2019-12-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) has been demonstrated to affect the oxidative stress status in several in vitro, in vivo and clinical studies. The aim of the present study was to evaluate the effect of a GLP-1 analogue, exenatide, on oxidative stress parameters and apoptotic markers in testicular cells in an iron over...

journal_title：Experimental and therapeutic medicine

authors： Yesil S,Sungu N,Kilicarslan A,Kuskonmaz SM,Kara H,Kucuk A,Polat F,Kavutcu M,Arslan M

更新日期：2018-12-01 00:00:00

abstract：:The primarily metabolic abnormality in type 2 diabetes mellitus (T2DM) is the defect in gluconeogenesis and glucose uptake. Itraconazole (ITCZ) is a traditional azole drug with anti-fungal and anticancer properties. However, limited attention has been directed towards the contribution of ITCZ to hepatic gluconeogenesi...

journal_title：Experimental and therapeutic medicine

authors： Na RS,Ma C,Liu QR,Wu LM,Zheng XL,Liu ZW

更新日期：2018-02-01 00:00:00

abstract：:Capillary density on nailfold capillaroscopy (NFC) is considered a promising instrument for assessing disease characteristics in patients with systemic sclerosis (SSc), however, there is no agreement yet over how to analyze and interpret the results. The objective of this study was to investigate the possible associat...

journal_title：Experimental and therapeutic medicine

authors： Gheorghiu AM,Oneata R,Ancuta I,Enuica A,Linte O,Macovei L,Bojinca M,Stoica V,Mihai C

更新日期：2020-10-01 00:00:00

abstract：:Excision repair cross-complementation group 1 (ERCC1) protein has been associated with cisplatin resistance. The objective of this study was to investigate the correlation between ERCC1 protein levels and the therapeutic effect of individualized therapy in advanced non-small cell lung cancer (NSCLC). A total of 190 ad...

journal_title：Experimental and therapeutic medicine

authors： Gao Z,Han B,Shen J,Gu A,Qi D,Huang J,Shi C,Xiong L,Zhao Y,Jiang L,Wang H,Chen Y

更新日期：2011-09-01 00:00:00