DSA-guided percutaneous sclerotherapy for children with oropharyngeal low-flow venous malformation.

Abstract:

:The present study investigated the efficacy and safety of digital subtraction angiography-guided 3% polidocanol foam sclerosing agent, as well as the combination of pingyangmycin and dexamethasone, for the treatment of children with oropharyngeal low-flow venous malformation. A total of 27 children with 35 lesions with oropharyngeal low-flow venous malformation were included. The subjects were randomly divided into Groups A (13 patients with 16 lesions, treated with 3% polidocanol foam sclerosing agent) and B (14 patients with 19 lesions, treated with pingyangmycin + dexamethasone), respectively. The clinical efficacies and adverse reactions were analyzed and compared between these two groups. The average number of treatment times for Group A was 2.45±0.6, with an efficacy rate of 87.50%, while the average number of treatment times for Group B was 2.07±0.4, with an efficacy rate of 84.21%. No significant difference was found in the average treatment times or efficacy rates between Groups A and B. In addition, the adverse reaction incidence for Groups A and B were 38.46 and 14.29%, respectively, with statistically significant differences between these two groups. The combination of pingyangmycin and dexamethasone was safe and effective in treating children with oropharyngeal low-flow venous malformation, with fewer adverse reactions and is worthy of clinical promotion.

journal_name

Exp Ther Med

authors

Song D,Guo L,Sheng H,Li J,Wang L,Wu C,Wang C,Niu Y,Zeng Q

doi

10.3892/etm.2020.8581

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

3405-3410

issue

5

eissn

1792-0981

issn

1792-1015

pii

ETM-0-0-8581

journal_volume

19

pub_type

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