A case of crusted scabies combined with bullous scabies.

abstract：:Bisphenol A (BPA) is an environmental pollutant that is widely produced throughout the world. It is primarily used in the manufacture of polycarbonate plastics, epoxy resins, paints and dental materials. BPA has been reported to promote hepatotoxicity and cardiotoxicity. The antioxidant activity of sesame lignans is w...

journal_title：Experimental and therapeutic medicine

authors： Eweda SM,Newairy ASA,Abdou HM,Gaber AS

更新日期：2020-01-01 00:00:00

abstract：:Neuropathic pain (NP) is a common clinical chronic pain with very complex mechanisms. This study explored the function of activated Wnt signaling pathway in NP. A rat model of chronic constriction injury (CCI) was established. Different doses of IWP-2, a Wnt signal inhibitor, were intrathecally injected to observe the...

journal_title：Experimental and therapeutic medicine

authors： Zhao Y,Yang Z

更新日期：2018-10-01 00:00:00

abstract：:The present study investigated the effect of the phytochemical genistein on the proliferation and differentiation of MCF-7 and 3T3-L1 cells via the regulation of estrogen receptor-α (ERα) expression and the induction of apoptosis. When MCF-7 human breast cancer cells were treated with 50, 100, 150 and 200 μM genistein...

journal_title：Experimental and therapeutic medicine

authors： Choi EJ,Jung JY,Kim GH

更新日期：2014-08-01 00:00:00

abstract：:Electrospinning using biocompatible polymer scaffolds, seeded with or without stem cells, is considered a promising technique for producing fibrous scaffolds with therapeutic possibilities for ischemic heart disease. However, no optimal scaffolds for treating ischemic heart disease have been identified thus far. In th...

journal_title：Experimental and therapeutic medicine

authors： Du M,Gu J,Wang J,Xue Y,Ma Y,Mo X,Xue S

更新日期：2019-05-01 00:00:00

abstract：:The aim of the present study was to explore the effects and mechanisms of insulin on mitochondrial oxidative stress in septic acute kidney injury (AKI). Male Sprague Dawley rats were divided randomly into four groups: Control group, sham surgery group, cecal ligation and puncture (CLP) group, and CLP plus insulin grou...

journal_title：Experimental and therapeutic medicine

authors： Chen GD,Zhang JL,Chen YT,Zhang JX,Wang T,Zeng QY

更新日期：2018-04-01 00:00:00

abstract：:The present case report describes a case of infantile myofibromatosis (IM) with a pseudo-ulcerated plaque on the right side of the back of a fetus, detected in the 38th week of gestation using prenatal ultrasound. The fetus was examined weekly by ultrasound to measure the size of the mass. At birth, the scarlet mass w...

journal_title：Experimental and therapeutic medicine

authors： Zhang F,Cheng D,Wu M,Ge L,Ma X

更新日期：2014-12-01 00:00:00

abstract：:Medical ozone is used to treat various diseases, including numerous pathologies associated with chronic pain. Chronic pain may be treated by systemic administration of ozone, with ozonated autohemotherapy (OAH) being the commonly used method. In the clinic, intravenous infusion of ozonized saline has been used to trea...

journal_title：Experimental and therapeutic medicine

authors： Ma L,Wen S,Yuan J,Zhang D,Lu YL,Zhang Y,Li Y,Cao S

更新日期：2020-09-01 00:00:00

abstract：:Tumor hypoxia contributes to the development of resistance to chemotherapeutic drugs in several human cancer cell lines. Atovaquone, an anti-malaria drug approved by the US Food and Drug Administration, has recently demonstrated anti-cancer effects in vitro and in vivo in several cancer models. To assess the potential...

journal_title：Experimental and therapeutic medicine

authors： Fu C,Xiao X,Xu H,Lu W,Wang Y

更新日期：2020-12-01 00:00:00

abstract：:Eukaryotic translation initiation factor (EIF) 5A2 exerts important functions that regulate the development and progression of cancers. The present study aimed to investigate the expression of EIF5A2 in prostate cancer (PCa) and its association with biological and prognostic significance. EIF5A2 mRNA and protein level...

journal_title：Experimental and therapeutic medicine

authors： Lu J,Zhao HW,Chen Y,Wei JH,Chen ZH,Feng ZH,Huang Y,Chen W,Luo JH,Fang Y

更新日期：2019-05-01 00:00:00

abstract：:The aim of this study is to determine the accuracy rate of bronchopulmonary dysplasia (BPD) diagnosis and risk factors of short-term poor prognosis for premature infants. This study analyzed the clinical data of 81 premature infants (<32 weeks gestational age) with BPD, who were on oxygen therapy >28 days, and survive...

journal_title：Experimental and therapeutic medicine

authors： Du Z,Kong X,Ren Y,Feng Z,Huang J,Chen J,Wang R

更新日期：2017-10-01 00:00:00

abstract：:Cyclooxygenase (COX)-2 inhibitors are widely used for postoperative pain control in clinical practice. However, it is unknown whether spinal sensitization is involved in the analgesic effects of COX-2 inhibitors on surgical pain. Extracellular signal-regulated kinase (ERK) in the spinal cord is implicated in various t...

journal_title：Experimental and therapeutic medicine

authors： Guo YJ,Shi XD,Fu D,Yang Y,Wang YP,Dai RP

更新日期：2013-07-01 00:00:00

abstract：:The present study evaluated the association between different Mycoplasma pneumoniae (M. pneumonia) genotypes and clinical features of pediatric patients. Subjects were children diagnosed with community-acquired pneumonia at the Children's Hospital of Soochow University (Suzhou, China) from January 2012 to December 201...

journal_title：Experimental and therapeutic medicine

authors： Fan L,Li D,Zhang L,Hao C,Sun H,Shao X,Xu J,Chen Z

更新日期：2017-09-01 00:00:00

abstract：:Cell-based tissue engineering has the potential to restore cartilage defects. Induced pluripotent stem cells (iPSCs) are regarded as an alternative cell source in regenerative medicine. The purpose of the present study was to evaluate the use of mesenchymal stem cells (MSCs) derived from human iPSCs (hiPSCs) for the r...

journal_title：Experimental and therapeutic medicine

authors： Xu X,Shi D,Liu Y,Yao Y,Dai J,Xu Z,Chen D,Teng H,Jiang Q

更新日期：2017-07-01 00:00:00

abstract：:Doxorubicin (DOX), a potent and widely used anticancer agent, can give rise to severe cardiotoxicity that limits its clinical use by inducing oxidative stress. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the central regulator of cellular responses to electrophilic/oxidative stress, which serves a critical ro...

journal_title：Experimental and therapeutic medicine

authors： Guo Z,Yan M,Chen L,Fang P,Li Z,Wan Z,Cao S,Hou Z,Wei S,Li W,Zhang B

更新日期：2018-10-01 00:00:00

abstract：:Previously, we performed a molecular pharmacological study that applied a combination of DNA microarray-based gene expression profiling and drug sensitivity tests in vitro with a view to designing an improved chemotherapeutic strategy for advanced lung cancer. Utilizing recent key technological advances in proteomics,...

journal_title：Experimental and therapeutic medicine

authors： Hino M,Matsuda K,Miyanaga A,Kuribayasi H,Mizutani H,Noro R,Minegishi Y,Okano T,Seike M,Kawakami A,Yoshimura A,Ogawa N,Uesaka H,Kudoh S,Gemma A

更新日期：2010-01-01 00:00:00

abstract：:The objective of this study was to investigate the protective effects of scopolamine and penehyclidine hydrochloride on acute cerebral ischemia-reperfusion injury after cardiopulmonary resuscitation, and the effect on cytokine levels. Eighty patients with cardiac arrest admitted to our hospital from June 2011 to Decem...

journal_title：Experimental and therapeutic medicine

authors： Wang D,Jiang Q,Du X

更新日期：2018-02-01 00:00:00

abstract：:The present study investigated the efficacy and safety of digital subtraction angiography-guided 3% polidocanol foam sclerosing agent, as well as the combination of pingyangmycin and dexamethasone, for the treatment of children with oropharyngeal low-flow venous malformation. A total of 27 children with 35 lesions wit...

journal_title：Experimental and therapeutic medicine

authors： Song D,Guo L,Sheng H,Li J,Wang L,Wu C,Wang C,Niu Y,Zeng Q

更新日期：2020-05-01 00:00:00

abstract：:At present, the majority of patients with breast cancer are diagnosed at early stages of disease development. However, a considerable number of such cases develop secondary malignancies after a relatively short period of time. The presence of circulating tumor cells (CTCs) has been proposed as a strong biomarker to pr...

journal_title：Experimental and therapeutic medicine

authors： Serrano MJ,Rovira PS,Martínez-Zubiaurre I,Rodriguez MD,Fernández M,Lorente JA

更新日期：2012-07-01 00:00:00

abstract：:The aim of the present study was to investigate whether chronic administration of basic fibroblast growth factor (bFGF) following angioplasty in a dog model of atherosclerotic iliac stenosis may restore endothelium function and prevent restenosis (RS). In total, 40 dogs with atherosclerotic stenosis of the right iliac...

journal_title：Experimental and therapeutic medicine

authors： Ran F,Liu C,Liu Z,Shang T,Zhou M,Qiao T

更新日期：2014-05-01 00:00:00

abstract：:The Global Registry of Acute Coronary Events (GRACE) risk score and the mean platelet volume to lymphocyte count ratio (MPVLR) can be used independently to predict adverse outcomes in patients with acute coronary syndromes. However, the level of MPVLR in relation to the GRACE score, and whether a combination of these ...

journal_title：Experimental and therapeutic medicine

authors： Chen X,Shao M,Zhang T,Zhang W,Meng Y,Zhang H,Hai H,Li G

更新日期：2020-06-01 00:00:00

abstract：:UNBS5162, a naphthalimide derivative, has a strong anticancer effect and low clinical hematological toxicity. UNBS5162 has been shown to have an anticancer effect in numerous cancer types, except triple negative breast cancer (TNBC). To explore this issue, TNBC MDA-MB-231 cells were selected, and the effect of UNBS516...

journal_title：Experimental and therapeutic medicine

authors： Yue X,Li M,Chen D,Xu Z,Sun S

更新日期：2018-11-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been indicated to serve critical roles in cancer development and progression. Long intergenic non-protein coding RNA 70 (LINC00707) was recently reported to be an oncogene involved in the tumorigenesis of several types of human cancer. However, the clinical role, biological function...

journal_title：Experimental and therapeutic medicine

authors： Wang H,Luan H,Zhan T,Liu X,Song J,Dai H

更新日期：2020-02-01 00:00:00

abstract：:Rutin has a variety of pharmacological actions, including radical reactivity, and protective activity against lipid peroxidation, viruses and acute pancreatitis; thus, it may be used as a treatment for many diseases. The present study aimed to investigate whether rutin inhibits coronary heart disease through extracell...

journal_title：Experimental and therapeutic medicine

authors： Lv L,Yao Y,Zhao G,Zhu G

更新日期：2018-01-01 00:00:00

abstract：:The current study assessed the association between toll-like receptor 9 (TLR9) and systemic lupus erythematosus (SLE) and subsequently determined the predictive value of TLR9 in assessing the prognosis of SLE. A total of 90 newly diagnosed patients with SLE and 49 healthy control subjects were enrolled in the current ...

journal_title：Experimental and therapeutic medicine

authors： Yuan Y,Zhao L,Ye Z,Ma H,Wang X,Jiang Z

更新日期：2019-04-01 00:00:00

abstract：:Astragaloside IV (AS-IV) in improving liver cirrhosis injury in rats and its effect on the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/mechanistic target of rapamycin (mTOR) signaling pathway were observed. Rat model of liver cirrhosis was induced by injection of carbon tetrachloride (CCl4). A total of 36 ...

journal_title：Experimental and therapeutic medicine

authors： Wei R,Liu H,Chen R,Sheng Y,Liu T

更新日期：2019-01-01 00:00:00

abstract：:Uterine carcinosarcoma (UCS) is a rare but very aggressive cancer of the female reproductive tract with an extremely poor prognosis. With the goal of understanding the role of microRNA (miRNA) dysregulation in these tumors, we profiled the expression of 667 human miRNAs in a panel of eight UCS patients and five benign...

journal_title：Experimental and therapeutic medicine

authors： Devor EJ,DE Mik JN,Ramachandran S,Goodheart MJ,Leslie KK

更新日期：2012-04-01 00:00:00

abstract：:NY-ESO-1 has been identified as one of the most immunogenic antigens; thus, is a highly attractive target for cancer immunotherapy. The present study analyzed the expression of serum antibodies (Abs) against NY-ESO-1 in patients with advanced colorectal cancer (CRC), with the aim of guiding the treatment of NY-ESO-1-b...

journal_title：Experimental and therapeutic medicine

authors： Long YY,Wang Y,Huang QR,Zheng GS,Jiao SC

更新日期：2014-10-01 00:00:00

abstract：:Resveratrol (3, 4', 5-trihydroxy-trans-stilbene) is a natural, non-flavonoid polyphenol that exerts protective properties against atherosclerosis-associated endothelial dysfunction and senescence. The present study aimed to assess the influence of resveratrol on vascular contractility and molecular factors including s...

journal_title：Experimental and therapeutic medicine

authors： Wiciński M,Malinowski B,Węclewicz MM,Grześk E,Grześk G

更新日期：2017-05-01 00:00:00

abstract：:Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by lower back pain, enthesitis and asymmetrical peripheral arthritis. Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as a first-line drug treatment for AS. The aim of the present study was to evaluate the efficacy and safety of...

journal_title：Experimental and therapeutic medicine

authors： Fan M,Liu J,Zhao B,Wu X,Li X,Gu J

更新日期：2020-04-01 00:00:00

abstract：:The present study performed a meta-analysis of randomized controlled trials in multiple sclerosis (MS) patients to evaluate the efficacy and safety of anti-B-cell monoclonal antibodies (mAbs). To the best of our knowledge, no previous meta-analysis has evaluated this. Relevant studies published until March 2015 were r...

journal_title：Experimental and therapeutic medicine

authors： Xie Q,Li X,Sun J,Yuan B,Li Y,Wang L,Wang M

更新日期：2017-06-01 00:00:00