Sulfated modification, characterization and monosaccharide composition analysis of Undaria pinnatifida polysaccharides and anti-tumor activity.

abstract：:Pulmonary embolism may escape prompt diagnosis since clinical symptoms and signs are nonspecific. The occurrence of syncope as the sole initial symptom in a previously healthy patient with no predisposing factors to embolism and no hemodynamic instability is extremely rare, which may have been a factor in the delayed ...

journal_title：Experimental and therapeutic medicine

authors： Jiang AG,Lu HY

更新日期：2013-05-01 00:00:00

abstract：:This study aimed to explore and evaluate the tolerability and antiviral activity of pegylated recombinant human consensus interferon-α (PEG-CIFN) in adults with hepatitis C virus (HCV) infection. A total of 48 adult subjects chronically infected with HCV were divided into five groups, which were treated separately wit...

journal_title：Experimental and therapeutic medicine

authors： Ding YH,Liu B,Zhang X,Sun L,Zhang H,Luo H,Sun YF,Liu CJ,Zhang Q,Cao YC,Chen H,Niu JQ

更新日期：2017-01-01 00:00:00

abstract：:The aim of the present study was to determine the protective effects of resveratrol on a rat model of osteoporosis and examine the associated mechanisms of its action. Rats were randomized into the following groups: Control, osteoporosis, osteoporosis + low-dose resveratrol, osteoporosis + middle-dose resveratrol and ...

journal_title：Experimental and therapeutic medicine

authors： Wang X,Chen L,Peng W

更新日期：2017-11-01 00:00:00

abstract：:Chronic exposure of workers to powder containing crystalline silica (Silicon dioxide; SiO2) can lead to chronic lung diseases (lung cancer, silicosis, etc.). Aim of this study was to evaluate the exposure of Greek construction workers to SiO2 and describe their pulmonary function. The study involved 86 outdoor and und...

journal_title：Experimental and therapeutic medicine

authors： Keramydas D,Bakakos P,Alchanatis M,Papalexis P,Konstantakopoulos I,Tavernaraki K,Dracopoulos V,Papadakis A,Pantazi E,Chelidonis G,Chaidoutis E,Constantinidis TC,Tsitsimpikou C,Kavantzas N,Patsouris E,Tsarouhas K,Spandidos

更新日期：2020-08-01 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a rare but highly aggressive type of malignancy. MicroRNA (miR)-25 has been demonstrated to be involved in the genesis of numerous cancer types. The aim of the present study was to investigate the prognostic value and functional role of miR-25 in CCA. The expression of miR-25 was determined...

journal_title：Experimental and therapeutic medicine

authors： Liu H,Ma L,Wang J

更新日期：2019-10-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2019.8114.]. ...

journal_title：Experimental and therapeutic medicine

authors： Fang L,Xu Z,Lu J,Hong L,Qiao S,Liu L,An J

更新日期：2021-02-01 00:00:00

abstract：:Calcineurin inhibitors (CNIs) such as cyclosporin A (CSA) and tacrolimus (FK506) are efficacious in patients with steroid-refractory or steroid-dependent ulcerative colitis (UC). We retrospectively investigated patients with refractory UC treated with CNIs to elucidate the prognostic factors for a colectomy. Data from...

journal_title：Experimental and therapeutic medicine

authors： Bamba S,Andoh A,Imaeda H,Ban H,Kobori A,Mochizuki Y,Shioya M,Nishimura T,Inatomi O,Sasaki M,Saitoh Y,Tsujikawa T,Fujiyama Y

更新日期：2012-07-01 00:00:00

abstract：:The aim of this study is to determine the accuracy rate of bronchopulmonary dysplasia (BPD) diagnosis and risk factors of short-term poor prognosis for premature infants. This study analyzed the clinical data of 81 premature infants (<32 weeks gestational age) with BPD, who were on oxygen therapy >28 days, and survive...

journal_title：Experimental and therapeutic medicine

authors： Du Z,Kong X,Ren Y,Feng Z,Huang J,Chen J,Wang R

更新日期：2017-10-01 00:00:00

abstract：:The aim of this study was to evaluate the safety of the continuous administration of recombinant human endostatin (Endostar) in healthy mice. A total of 16 nude mice were randomly divided into four treatment groups: a continuous administration group injected intraperitoneally (i.p.) with 14 mg/kg Endostar over seven d...

journal_title：Experimental and therapeutic medicine

authors： Huang R,Zhan Q,Zhou X,Chu Z,Jiang J,Liang X

更新日期：2012-06-01 00:00:00

abstract：:The aim of the present study was to investigate the protective effects of sodium ferulate (SF) on HT22 hippocampal cells under a high glucose concentration. Cells were cultured in normal glucose (25 mM D-glucose) or high glucose (50 mM D-glucose) with various concentrations of SF (50, 100, 250 or 500 µM) for 0, 48 and...

journal_title：Experimental and therapeutic medicine

authors： Zhao J,Liu L,Zhang L,Lv J,Guo X,Li X,Zhao T

更新日期：2019-09-01 00:00:00

abstract：:The hypoxia-reoxygenation process of obstructive sleep apnea (OSA) may cause oxidative stress injury of the kidney, but the molecular mechanisms are not clear. The present study aimed to investigate whether high mobility group box 1 protein (HMGB1) and its subsequent inflammatory pathway served a role in kidney injury...

journal_title：Experimental and therapeutic medicine

authors： Zhang C,Dong H,Chen F,Wang Y,Ma J,Wang G

更新日期：2019-01-01 00:00:00

abstract：:Meibomian gland dysfunction (MGD) is a major cause of dry eye, and the purpose of the present study was to evaluate the differences between dry eye patients with MGD and controls using a novel noninvasive ocular surface analyzer. A total of 33 dry eye patients with MGD and 31 controls were enrolled in the present stud...

journal_title：Experimental and therapeutic medicine

authors： Qi Y,Zhang C,Zhao S,Huang Y,Yang R

更新日期：2017-06-01 00:00:00

abstract：:Effect of total glucosides of paeony on the changes of IL-4 and ICAM-1 levels in eczema mouse model serum was investigated. A total of 38 KM mice of SPF grade were divided into 3 groups: the control group (n=10), the model group (n=15) and the treatment group (n=13). The pathological model of chronic eczema in mouse r...

journal_title：Experimental and therapeutic medicine

authors： Zhou M,Sui H

更新日期：2019-03-01 00:00:00

abstract：:Granulomatosis with polyangiitis (GPA) is a rheumatic auto-immune disease involved in vasculitis. It is rarely reported that anti-neutrophil cytoplasmic antibodies (ANCAs) associated with GPA would cause main tract stenosis. The current report documents a 54-year-old woman, with a history of severe cough, presented wi...

journal_title：Experimental and therapeutic medicine

authors： Zhou D,Zhang P,Zhang Y,Zhang Y,Zhang X,Li J,Zhou Z,Zhu N

更新日期：2020-05-01 00:00:00

abstract：:Intervertebral disc degeneration (IDD) is considered to be the main cause of many spinal disorders; however, its underlying pathophysiology is not clearly understood. Recent studies indicate that excessive mechanical loading may serve a major role in the initiation of IDD. The aim of the present study was to explore t...

journal_title：Experimental and therapeutic medicine

authors： Bai X,Wang D,Zhou M,Xu C,Li W,Tao H,He Q,Ruan D

更新日期：2017-04-01 00:00:00

abstract：:The present study aimed to investigate the effects of mechanical stretch and lipopolysaccharides (LPS) on the expression of transforming growth factor-β1 (TGF-β1) and collagen and viscoelasticity in human embryonic MRC-5 lung fibroblasts cultured in vitro and to assess the mechanisms of ARDS-associated ventilator-indu...

journal_title：Experimental and therapeutic medicine

authors： Xie Y,Qian Y,Wang Y,Liu K,Li X

更新日期：2020-11-01 00:00:00

abstract：:The aim of this study was to isolate and purify Rhizoma Pinelliae trypsin inhibitor (RPTI), determine its N-terminal amino acid sequence and evaluate its inhibitory effect on the proliferation of poorly differentiated BGC-823 human gastric adenocarcinoma cells. RPTI was separated and purified from a 40% (NH4)2SO4 prec...

journal_title：Experimental and therapeutic medicine

authors： Zu G,Wang H,Wang J,Dou Y,Zhao W,Sun Y

更新日期：2014-07-01 00:00:00

abstract：:The current study aimed to investigate the effect of sepsis on rat serotonin (5-HT) responses and cardiac action potentials. A total of 20 rats were randomly divided into a sepsis and control group (each, n=10). Rat hearts were harvested and perfused using the Langendorff method 18-h after the induction of sepsis, whi...

journal_title：Experimental and therapeutic medicine

authors： Liu ZJ,Liu H,Wu C,Xue K

更新日期：2019-09-01 00:00:00

abstract：:The aim of this study was to evaluate the clincal value of multi-slice spiral computed tomography (MSCT) in the diagnosis of double aortic arch (DAA) and analyze the associated angiography and 3D reconstruction imaging to increase the accuracy of DAA diagnosis. Clinical and imaging data from 15 patients diagnosed with...

journal_title：Experimental and therapeutic medicine

authors： Chen X,Qu Y,Peng ZY,Lu J,Ma X,Hu W

更新日期：2014-08-01 00:00:00

abstract：:Endometriosis (EM) is associated with oxidative stress. Advanced oxidation protein products (AOPPs) are novel markers of oxidative stress, which serve an important role as an inflammatory mediator in various chronic diseases. In order to examine the role of AOPPs in infertile women with EM, the present study analyzed ...

journal_title：Experimental and therapeutic medicine

authors： Song Y,Liu J,Qiu Z,Chen D,Luo C,Liu X,Hua R,Zhu X,Lin Y,Li L,Liu W,Quan S

更新日期：2018-01-01 00:00:00

abstract：:Chronic myelogenous leukemia (CML) is a condition characterized by a balanced genetic translocation, t (9;22) (q34;q11.2), which leads to a fusion of the Abelson oncogene (ABL) from chromosome 9q34 with the breakpoint cluster region (BCR) gene on chromosome 22q11.2. This rearrangement is referred to as the Philadelphi...

journal_title：Experimental and therapeutic medicine

authors： Shen X,Zhang M,Shen Y,Shi W,Liu W,Wei WU

更新日期：2015-10-01 00:00:00

abstract：:Atherosclerosis is caused by various factors, and Glabridin may have protective effects on the cardiovascular system. The purpose of the present study was to evaluate the effects of Glabridin on atherosclerosis and evaluate whether Glabridin attenuates arteriosclerosis and endothelial permeability by suppressing the m...

journal_title：Experimental and therapeutic medicine

authors： Wang G,Sun G,Wang Y,Yu P,Wang X,Zhou B,Zhu H

更新日期：2019-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2017.4943.]. ...

journal_title：Experimental and therapeutic medicine

authors： Li S,Xu G,Gao F,Bi J,Huo R

更新日期：2018-10-01 00:00:00

abstract：:In patients undergoing off-pump coronary artery bypass surgery (OPCAB), it is important to attenuate myocardium injury during the surgery. The present study aimed to observe the cardioprotection induced by sevoflurane induction and maintenance compared with propofol intravenous anesthesia, and to detect its potential ...

journal_title：Experimental and therapeutic medicine

authors： Liu X,Liu X,Wang R,Luo H,Qin G,Wang LU,Ye Z,Guo Q,Wang E

更新日期：2016-06-01 00:00:00

abstract：:The aim of the present study was to investigate the role and mechanism of vascular cell adhesion molecule-1 (VCAM-1) in the development of rheumatoid arthritis (RA). One hundred and twenty patients with RA who had been admitted to the Huaihe Hospital of Henan University between January and December 2013 were enrolled ...

journal_title：Experimental and therapeutic medicine

authors： Wang L,Ding Y,Guo X,Zhao Q

更新日期：2015-09-01 00:00:00

abstract：:Subclinical hypothyroidism (SCH) is becoming a global health problem due to its increasing prevalence and potential adverse effects, including cardiovascular diseases and nonalcoholic fatty liver disease (NAFLD). However, the association between SCH and NAFLD remains controversial. MicroRNAs (miRNAs/miRs) have been re...

journal_title：Experimental and therapeutic medicine

authors： Zhang L,Wu K,Bo T,Zhou L,Gao L,Zhou X,Chen W

更新日期：2020-02-01 00:00:00

abstract：:Paraquat (PQ) is a highly toxic herbicide, which not only leads to acute organ damage, but also to a variety of complications. Patients with severe PQ-induced poisoning may succumb to multiple organ failure involving the circulatory and respiratory systems. Although numerous studies have been performed investigating P...

journal_title：Experimental and therapeutic medicine

authors： Song C,Kan B,Yu G,Jian X,Wang J,Sun J

更新日期：2014-11-01 00:00:00

abstract：:Obesity and β-cell dysfunction due to oxidative stress impact the pathogenesis of type 2 diabetes mellitus. We co-cultured 3T3L1 adipocytes and islet cells in the presence or absence of the antioxidant α-lipoic acid (LA) and assayed the effects of the adipocytes and LA on the secretion of insulin by the islet cells an...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Dong W,Ding X,Wang F,Wang Y,Chen X,Yu L,Li X,Zhang A,Peng Y

更新日期：2012-09-01 00:00:00

abstract：:Angelicin is an active compound isolated from the Chinese herb Angelica archangelica, which has been reported to exert antitumor effects by inhibiting malignant behaviors in several types of tumor, including proliferation, colony formation, migration and invasion. However, the effects of angelicin on human cervical ca...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Chen Y,Chen X,Liang Y,Yang D,Dong J,Yang N,Liang Z

更新日期：2019-11-01 00:00:00

abstract：:The Philips Intellivue MP50 monitor provides a method for non-invasive, near-continuous blood pressure (BP) monitoring and is designed to be an alternative to direct intra-arterial BP (IABP) measurement. However, no studies have specifically compared non-invasive and invasive BP measurements using the monitor. The pre...

journal_title：Experimental and therapeutic medicine

authors： Meng X,Zang G,Fan L,Zheng L,Dai J,Wang X,Xia W,Liu J,Zhang C

更新日期：2013-07-01 00:00:00