Agnogenic massive pulmonary embolism with syncope as initial symptom: A case report and review of the literature.

abstract：:Herpes Zoster (HZ) is reported as the most prevalent viral infection in patients with systemic lupus erythematosus (SLE). The aim of the present study was to investigate the clinical features, complications, and potential risk factors of HZ in patients with SLE from Southern China. A retrospective study was performed ...

journal_title：Experimental and therapeutic medicine

authors： Chen D,Li H,Xie J,Zhan Z,Liang L,Yang X

更新日期：2017-12-01 00:00:00

abstract：:The aim of the present study was to investigate the functional status of dendritic cells (DCs) in nasal polyps (NP) and their interactions with T lymphocytes. The interactions between DC and T lymphocytes in the pathogenesis of NP was also studied. The expression of cluster of differentiation (CD)1a and CD83 in NP was...

journal_title：Experimental and therapeutic medicine

authors： Lin X,Zhuang X,Li C,Wang X

更新日期：2018-06-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) serve important roles in colorectal cancer. The aim of the present study was to investigate the expression and role of cervical carcinoma expressed PCNA regulatory (CCEPR) lncRNA in colorectal cancer progression. The results demonstrated that CCEPR expression was significantly higher in ...

journal_title：Experimental and therapeutic medicine

authors： Duan Y,Fang Z,Shi Z,Zhang L

更新日期：2019-11-01 00:00:00

abstract：:To evaluate how metformin plus rosiglitazone affect serum adiponectin levels in people suffering from type 2 diabetes mellitus (T2DM), 240 patients having T2DM were selected in this cohort study. Included subjects were randomly and equally separated into three subsets: i) Group A (rosiglitazone group); ii) group B (me...

journal_title：Experimental and therapeutic medicine

authors： Nie JM,Li HF

更新日期：2017-09-01 00:00:00

abstract：:The present study aimed to investigate the effect of triptolide (TL) on ulcerative colitis (UC) and explore the potential association between the therapeutic effects of TL and IL-1β expression using a 4,4-dimethyl-4-silapentane-1-sulfonic acid (DSS)-induced mouse model to simulate human UC. A total of 70 BALB/c female...

journal_title：Experimental and therapeutic medicine

authors： Zhang H,Gong C,Qu L,Ding X,Cao W,Chen H,Zhang B,Zhou G

更新日期：2016-09-01 00:00:00

abstract：:Currently prophylactic HPV16/18 L1 virus-like particle (VLP) vaccines are employed with great success for the prevention of HPV infection. However, limited information is available regarding the immune responses against human papillomavirus (HPV) 16/18 L1 subsequent to HPV16/18 L1 VLP vaccination, primarily due to the...

journal_title：Experimental and therapeutic medicine

authors： Yokomine M,Matsueda S,Kawano K,Sasada T,Fukui A,Yamashita T,Komatsu N,Shichijo S,Tasaki K,Matsukuma K,Itoh K,Kamura T,Ushijima K

更新日期：2017-04-01 00:00:00

abstract：:The present study aimed to evaluate the safety and efficiency of ciliary sulcus implantation of intraocular lens (IOL) in patients that had undergone manual small incision cataract surgery (MSICS) complicated by large posterior capsule rupture (LPCR). A total of 11 eyes taken from 11 patients in Brazzaville, Republic ...

journal_title：Experimental and therapeutic medicine

authors： Zhao J,Yu J,Wang T,Mban B

更新日期：2019-02-01 00:00:00

abstract：:Caspase-8 (encoded by the CASP-8 gene) is crucial in generating cell death signals and eliminating potentially malignant cells. Genetic variation in CASP8 may affect susceptibility to cancer. The CASP-8 -652 6N ins/del (rs3834129) polymorphism has been previously reported to influence the progression to several cancer...

journal_title：Experimental and therapeutic medicine

authors： Chen D,Ma T,Liu XW,Liu Z

更新日期：2012-10-01 00:00:00

abstract：:In the present study, the risk factors for systemic air embolism as a complication of percutaneous CT-guided lung biopsy were explored. Data from 2,026 percutaneous CT-guided lung biopsy procedures were retrospectively analyzed. All cases were divided into a concurrent air embolism group and a control group, depending...

journal_title：Experimental and therapeutic medicine

authors： Liu SH,Fu Q,Yu HL,Yang Q,Hu YB,Zhang ZX,Zhang BP,Zhang CY

更新日期：2020-01-01 00:00:00

abstract：:In the present study, we investigated the effects of hydroxyethyl starch (HES) 130/0.4 on serum pro-inflammatory variables, immunologic variables, fluid balance (FB)-negative(-) rate and renal function in severe acute pancreatitis (SAP) patients. From October, 2007 to November, 2008, a total of 120 SAP patients were e...

journal_title：Experimental and therapeutic medicine

authors： Chen QJ,Yang ZY,Wang CY,Dong LM,Zhang YS,Xie C,Chen CZ,Zhu SK,Yang HJ,Wu HS,Yang C

更新日期：2016-11-01 00:00:00

abstract：:High-mobility group box 1 (HMGB1) is released after focal cerebral ischemia/reperfusion (I/R), and aggravates brain tissue damage. Ginsenoside Rb1 (Rb1), isolated from Panax ginseng, has been reported to inhibit I/R-induced cell death in the brain. The present study aimed to investigate the protective ability of GRb1 ...

journal_title：Experimental and therapeutic medicine

authors： Liu A,Zhu W,Sun L,Han G,Liu H,Chen Z,Zhuang L,Jiang W,Xue X

更新日期：2018-10-01 00:00:00

abstract：:In this study, to assess whether aqueous and ethanol fractions of Angelica keiskei induce acute skin irritation and phototoxicity, acute skin irritancy and phototoxicity tests were performed. The skin of rabbits or guinea pigs was treated with these fractions (100 mg/dose) and whether the animals sustained significant...

journal_title：Experimental and therapeutic medicine

authors： Lee SH

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to investigate the effects of heat stress on the expression of the coxsackievirus and adenovirus receptor (CAR) in mouse skin keratinocytes. Twenty BALB/c mice were randomly divided into two groups: the sham heat (control) and scald groups. Skin specimens were obtained 6 h after the treatment...

journal_title：Experimental and therapeutic medicine

authors： Deng X,Jia C,Chen F,Liu J,Zhou Z

更新日期：2013-10-01 00:00:00

abstract：:Discoid lateral meniscus of the knee causes a high morbidity in China. Since the traditional treatment to open the capsule and resect the meniscus often results in arthritis, it is now believed that a discoid lateral meniscus should be treated with arthroscopy to preserve part of the meniscus. The current study aimed ...

journal_title：Experimental and therapeutic medicine

authors： Cao H,Zhang Y,Qian W,Cheng XH,Ke Y,Guo XP

更新日期：2012-11-01 00:00:00

abstract：:Chitosan, a naturally derived polymer, has been shown to possess antimicrobial and anti-inflammatory properties; however, little is known about the effect of chitosan on the immune responses and glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT) and lactate dehydrogenase (LDH) activities in n...

journal_title：Experimental and therapeutic medicine

authors： Yeh MY,Shih YL,Chung HY,Chou J,Lu HF,Liu CH,Liu JY,Huang WW,Peng SF,Wu LY,Chung JG

更新日期：2016-04-01 00:00:00

abstract：:Gardenia fruit has been used in traditional Chinese medicine for thousands of years. A previous study by the present authors indicated that the ethanol extract of gardenia fruits (EEG) primarily contains eight constituents. In the present study, the potential effects of EEG on unilateral ureteral obstruction (UUO)-ind...

journal_title：Experimental and therapeutic medicine

authors： Li X,Ma M,Zhang X,Deng L,Wang Y,Bian Z,Cai S,Peng B,Yang J,Chen Y

更新日期：2017-08-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is the most common congenital infection worldwide, and remains a significant cause of the neurological deficiency and sensory deafness in developed countries. Maternal primary infection, reactivation or reinfection during pregnancy may lead to fetal infection and congenital CMV syndrome...

journal_title：Experimental and therapeutic medicine

authors： Gorun F,Motoi S,Malita D,Navolan DB,Nemescu D,Olariu TR,Craina M,Vilibic-Cavlek T,Ciohat I,Boda D,Dobrescu A

更新日期：2020-09-01 00:00:00

abstract：:The aim of the present study was to investigate whether the co-injection of hyaluronic acid (HA) and corticosteroids (CS) was superior to HA alone in the treatment of knee OA. A total of 120 participants with symptomatic knee OA were recruited and formed the intention-to-treat population for a 6-month follow-up. In th...

journal_title：Experimental and therapeutic medicine

authors： Wang SZ,Wu DY,Chang Q,Guo YD,Wang C,Fan WM

更新日期：2018-09-01 00:00:00

abstract：:This review presents a systematic analysis of the literature regarding the pachychoroid disease spectrum nomenclature, diagnosis criteria and therapeutic options. Pachychoroid related diseases are a new concept, introduced into the ophthalmological nomenclature in 2013 and evolving both as concept and as classificatio...

journal_title：Experimental and therapeutic medicine

authors： Moraru AD,Costin D,Moraru RL,Costuleanu M,Brănișteanu DC

更新日期：2020-10-01 00:00:00

abstract：:The aim of this study was to investigate and analyze the effects of human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) on the recovery of neurological function and telomerase reverse transcriptase (TERT) expression in brain tissue of rats with cerebral ischemia-reperfusion injury. A total of 100 healthy adu...

journal_title：Experimental and therapeutic medicine

authors： Huang X,Zhang S,Li F,Zhou Y,Wang X,Fu G,Ma X

更新日期：2017-12-01 00:00:00

abstract：:In the present study the preventive effect of polysaccharides from the large yellow croaker swim bladder (PLYCSB) on HCl/ethanol-induced gastric injury in ICR mice was investigated. A high dose of PLYCSB (50 mg/kg) was found to reduce the levels of the serum proinflammatory cytokines interleukin (IL)-1β, IL-6, IL-8, a...

journal_title：Experimental and therapeutic medicine

authors： Chen S,Zhu K,Wang R,Zhao X

更新日期：2014-07-01 00:00:00

abstract：:The aim of this study was to use proteomic and transcriptomic approaches to examine differences in protein and gene expression in maternal plasma between normal and preeclamptic pregnancies. Preeclampsia and control groups were compared with respect to the expression of CD34 and CD133 genes by quantitative polymerase ...

journal_title：Experimental and therapeutic medicine

authors： Sahin H,Gunel T,Benian A,Onay Ucar E,Guralp O,Kilic A

更新日期：2015-08-01 00:00:00

abstract：:Epilepsy is one of the few neurologic disorders that requires a constant treatment during pregnancy. Epilepsy affects 0.3-0.8% of pregnant women. Prescription of antiepileptic drugs (AEDs) to pregnant women with epilepsy requires monitoring and maintaining a balance between limiting seizures and decreasing fetal expos...

journal_title：Experimental and therapeutic medicine

authors： Nie Q,Su B,Wei J

更新日期：2016-10-01 00:00:00

abstract：:Neuregulin-1 (NRG-1) is a cardioactive growth factor released from endothelial cells. However, the effect of NRG-1 on ventricular remodeling in diabetic cardiomyopathy (DCM) remains unclear. The aim of the present study was to investigate the pathophysiological role of NRG-1 in a rat model of DCM. Rat cardiac microvas...

journal_title：Experimental and therapeutic medicine

authors： Li B,Xiao J,Li Y,Zhang J,Zeng M

更新日期：2013-11-01 00:00:00

abstract：:Acute promyelocytic leukemia (APL) with variant translocations is rare. The patient of the present case report, a 2-year-old male with a microgranular variant of APL carrying der(17) ins(17;15) translocation, exhibited fever and epistaxis. The complete blood count showed marked leukocytosis with 72% atypical promyeloc...

journal_title：Experimental and therapeutic medicine

authors： Guan H,Liu J,Guo X,Wu C,Yu H

更新日期：2015-09-01 00:00:00

abstract：:Flos Chrysanthemi Indici (CI) is a traditional medicinal plant used in the treatment of inflammatory diseases. However, the pharmacological role of CI in metabolic diseases, especially in diseases induced by insulin metabolism disorders, remains poorly understood. In the present study, Drosophila melanogaster (Drosoph...

journal_title：Experimental and therapeutic medicine

authors： Bai Y,Li K,Shao J,Luo Q,Jin LH

更新日期：2018-09-01 00:00:00

abstract：:The aim of the present study was to screen for biomarkers of Parkinson's disease (PD) using proteomics and bioinformatics approaches. PD patients were divided into three groups: Those without surgery (PD1 group); those who had undergone deep brain stimulation (DBS) surgery without electrode stimulation (PD2 group); an...

journal_title：Experimental and therapeutic medicine

authors： Dong W,Qiu C,Gong D,Jiang X,Liu W,Liu W,Zhang L,Zhang W

更新日期：2019-10-01 00:00:00

abstract：:Effects of ropivacaine at different concentrations on intrapartum fever, interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in parturient with epidural labor analgesia were compared to provide reference for the rational selection of anesthetics in clinic. Medical records of 198 cases of primi-paras admitted to t...

journal_title：Experimental and therapeutic medicine

authors： Zhou X,Li J,Deng S,Xu Z,Liu Z

更新日期：2019-03-01 00:00:00

abstract：:The effects of recombinant human growth hormone (rhGH) in the treatment of dwarfism and the relationship between insulin-like growth factor (IGF)-1, IGF-binding protein (IGFBP)-3 and thyroid hormone were examined in the present study. For this purpose, 66 patients diagnosed with dwarfism were selected retrospectively,...

journal_title：Experimental and therapeutic medicine

authors： Ren S,Nie Y,Wang A

更新日期：2016-12-01 00:00:00

abstract：:The effects of atrial fibrillation on complications and prognosis of patients receiving emergency percutaneous coronary intervention after acute myocardial infarction (AMI) were investigated. Eighty AMI patients treated with interventional vascular recanalization in the Affiliated Hospital of Weifang Medical Universit...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Zhang L,Zheng H,Chen H

更新日期：2018-10-01 00:00:00