Clinicopathological findings in a case series of abdominopelvic solitary fibrous tumors.

abstract：:Hyperparathyroidism is characterized by the oversecretion of parathyroid hormone biochemically and increased cell proliferation histologically. Primary and secondary hyperparathyroidism exhibit distinct pathophysiology but share certain common microscopic features. The present study performed the first genome-wide exp...

journal_title：Oncology letters

authors： Lee F,Lee JJ,Jan WC,Wu CJ,Chen HH,Cheng SP

更新日期：2016-07-01 00:00:00

abstract：:The role of mitogen-activated protein kinase (MAPK) signaling pathways in cell growth and differentiation has been well established. The present study aimed to investigate the anti-proliferative effect of stevioside on human colon cancer HT-29 cells. Additionally, the effect of stevioside on cell cycle arrest and MAPK...

journal_title：Oncology letters

authors： Ren HP,Yin XY,Yu HY,Xiao HF

更新日期：2017-04-01 00:00:00

abstract：:Multiple myeloma is defined as a malignant proliferation of a single clone of plasma cells resulting in monoclonal immunoglobulin production. Due to the number of plasma cell morphological variants, difficulty is often faced during morphological diagnosis. The current study describes the case of a 49-year-old woman pr...

journal_title：Oncology letters

authors： Jiang P,Xia W,Sun X,Dai X,Li L

更新日期：2016-03-01 00:00:00

abstract：:The present study investigated the anticancer functions of ursolic acid (UA) and its novel derivatives, with a nitrogen-containing heterocyclic scaffold and the privileged fragment at the C-28 position on apoptosis induction, cell proliferation and cell cycle in human BC lines. UA was chemically modified in the presen...

journal_title：Oncology letters

authors： Li W,Zhang H,Nie M,Wang W,Liu Z,Chen C,Chen H,Liu R,Baloch Z,Ma K

更新日期：2018-02-01 00:00:00

abstract：:Numerous studies have indicated that microRNAs (miRs), a group of small non-coding RNAs, are determining regulatory elements involved in the pathogenesis of various types of cancer, including cervical cancer (CC). Although miR-21-5p upregulation has been demonstrated to associate with tumorigenesis by controlling the ...

journal_title：Oncology letters

authors： Cai L,Wang W,Li X,Dong T,Zhang Q,Zhu B,Zhao H,Wu S

更新日期：2018-04-01 00:00:00

abstract：:Radiofrequency ablation has become an increasingly common therapeutic technique for patients with hepatocellular carcinoma or metastatic liver tumors. However, reports on the effect of percutaneous radiofrequency ablation (PRFA) on circulating tumor cells (CTCs) are limited. The present study aimed to further investig...

journal_title：Oncology letters

authors： Li Y,Huang N,Wang C,Ma H,Zhou M,Lin L,Huang Z,Sun L,Shi M,Liao W

更新日期：2018-09-01 00:00:00

abstract：:The aim of this study was to detect methylation of the RAR-β gene in tissues from non-small cell lung cancer (NSCLC) patients. The methylation of the RAR-β gene in DNA from 80 cases with NSCLC and corresponding non-malignant tissues was tested using methylation-specific polymerase chain reaction (PCR; MSP). The result...

journal_title：Oncology letters

authors： Zhao X,Wang N,Zhang M,Xue S,Shi K,Chen Z

更新日期：2012-03-01 00:00:00

abstract：:Endostar, a modified recombinant human endostatin, inhibits the growth of a variety of tumors by suppressing neovascularization. Vascular endothelial growth factor (VEGF) has an important role in malignant ascites formation. In order to determine whether Endostar can suppress the formation of ascites and prolong survi...

journal_title：Oncology letters

authors： Wei H,Qin S,Yin X,Chen Y,Hua H,Wang L,Yang N,Chen Y,Liu X

更新日期：2015-06-01 00:00:00

abstract：:Local adjuvant treatment of giant cell tumours (GCTs) of the bone with phenol has led to a significant reduction in recurrence rates. In the current study, the optimal phenol concentration and duration of intralesional exposure were evaluated. Specimens of GCTs were exposed to various concentrations of phenol solution...

journal_title：Oncology letters

authors： Mittag F,Leichtle C,Kieckbusch I,Wolburg H,Rudert M,Kluba T,Leichtle U

更新日期：2013-05-01 00:00:00

abstract：:The present study aimed to retrospectively review the contribution of 18F-fluorodeoxygluose-positron emission tomography/computed tomography (18F-FDG PET/CT) in the assessment of biochemical recurrence in patients with a diagnosis of local-stage prostate cancer (PCa) who underwent radical prostatectomy (RP) or receive...

journal_title：Oncology letters

authors： Öztürk H,Karapolat I

更新日期：2016-01-01 00:00:00

abstract：:The incidence of gastric cancer is high, especially in China. The present study aims to provide a novel therapeutic target for gastric cancer. Peripheral blood, cancerous and paracancerous tissues were collected from patients with gastric cancer. T-cell immunoglobulin mucin domain-3 (Tim-3) expression in T-cells was m...

journal_title：Oncology letters

authors： Yu J,Zhang H,Sun S,Sun S,Li L

更新日期：2019-02-01 00:00:00

abstract：:V-domain immunoglobulin suppressor of T cell activation (VISTA) is a novel negative immune checkpoint that belongs to the B7 family. VISTA is primarily expressed on hematopoietic cells and inhibits T cell proliferation and cytokine production. The blockade of VISTA has demonstrated promising results in certain murine ...

journal_title：Oncology letters

authors： Liao H,Zhu H,Liu S,Wang H

更新日期：2018-09-01 00:00:00

abstract：:Previous studies have demonstrated that the chronic administration of valproic acid (VPA) suppresses angiogenesis in vivo; however, the mechanisms implicated in VPA-induced autophagy remain unclear. The current study aimed to assess VPA-induced autophagy in three prostate cancer cell lines (PC3, DU145 and LNCaP), in a...

journal_title：Oncology letters

authors： Xia Q,Zheng Y,Jiang W,Huang Z,Wang M,Rodriguez R,Jin X

更新日期：2016-09-01 00:00:00

abstract：:The present study aimed to investigate the anticancer effects of corosolic acid (CA) in the human lung adenocarcinoma A549 cell line. A549 cells were treated with increasing concentrations of CA, prior to assessing cell viability, migration rate, vascular endothelial growth factor receptor 2 (VEGFR2) kinase activity a...

journal_title：Oncology letters

authors： Li B,Li Y,Wang Q,Li F,Li F

更新日期：2019-06-01 00:00:00

abstract：:The upregulation of EPH receptor B4 (EPHB4) results in a survival advantage for tumor cells via the inhibition of the casapse-8-mediated apoptotic pathway, which begins from the cell membrane. The present study investigated the expression patterns of EPHB4, ephrin B2 (EFNB2) and caspase-8 in patients with esophageal s...

journal_title：Oncology letters

authors： Ni Q,Chen P,Zhu B,Li J,Xie D,Ma X

更新日期：2020-01-01 00:00:00

abstract：:The present study aimed to evaluate the effects of amentoflavone on sorafenib-induced apoptosis in sorafenib-resistant hepatocellular carcinoma (HCC) cells. The sorafenib-resistant SK-Hep1 (SK-Hep1R) cell line was established for the present study. Initially, the differences in sorafenib-induced cytotoxicity and apopt...

journal_title：Oncology letters

authors： Chen WL,Hsieh CL,Chen JH,Huang CS,Chen WT,Kuo YC,Chen CY,Hsu FT

更新日期：2017-09-01 00:00:00

abstract：:Myelolipoma is a rare, benign neoplasm composed of mature adipocytes and hematopoietic tissue, mainly occurring in the adrenal glands. The majority of extra-adrenal myelolipomas have been identified in the presacral region and primary mediastinal myelolipoma is very rare. Computed tomography (CT) and magnetic resonanc...

journal_title：Oncology letters

authors： Geng C,Liu N,Yang G,Qi M,Chen W

更新日期：2013-03-01 00:00:00

abstract：:It has been reported that zerumbone (ZER) has marked effects on the regulation of cell proliferation and migration in multiple types of cancer, and has anti-cancer effects on various types of malignant cell. However, the effects and underlying molecular mechanisms of treatment with ZER on melanoma cells remain unclear...

journal_title：Oncology letters

authors： Yan H,Ren MY,Wang ZX,Feng SJ,Li S,Cheng Y,Hu CX,Gao SQ,Zhang GQ

更新日期：2017-04-01 00:00:00

abstract：:The aim of the study was to determine whether interleukin-8 (IL-8) affects human SKOV3 ovarian cancer cell migration and invasion by targeting silencing of IL-8 expression. Silencing small-interfering RNA (siRNA) targeting IL-8 gene was constructed to infect SKOV3 cells by lentiviral vector. The expression of IL-8 and...

journal_title：Oncology letters

authors： Li Y,Liu L,Yin Z,Xu H,Li S,Tao W,Cheng H,Du L,Zhou X,Zhang B

更新日期：2017-02-01 00:00:00

abstract：:Non-Hodgkin lymphoma of the bone is rare and typically causes an extensive bone lesion. The present study describes a case of diffuse large B-cell primary non-Hodgkin lymphoma of the bone, which occurred in the right femur, and was initially treated with surgery and chemotherapy. Following a 7-year period of complete ...

journal_title：Oncology letters

authors： Hu JY,Yu D,Wu YH

更新日期：2018-04-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) can result from hepatitis B or C infection, fibrosis or cirrhosis. Transforming growth factor-β (TGF-β) is one of the main growth factors associated with fibrosis or cirrhosis progression in the liver, but its role is controversial in hepatocarcinogenesis. In the present study, the effec...

journal_title：Oncology letters

authors： Kim JB,Lee S,Kim HR,Park SY,Lee M,Yoon JH,Kim YJ

更新日期：2018-06-01 00:00:00

abstract：:Stromal cell-derived factor 1α (SDF1α) and its receptor C-X-C chemokine receptor type 4 (CXCR4) have been reported to form an important chemokine signaling pathway. Our previous study reported that SDF1α from tumor stromal cells may stimulate the proliferation of gastric cancer (GC) cells through the CXCR4 axis in a h...

journal_title：Oncology letters

authors： Yashiro M,Kinoshita H,Tsujio G,Fukuoka T,Yamamoto Y,Sera T,Sugimoto A,Nishimura S,Kushiyama S,Togano S,Kuroda K,Toyokawa T,Ohira M

更新日期：2021-01-01 00:00:00

abstract：:A 39-year-old female presented to The First Affiliated Hospital of Jishou University (Jishou, Hunan) with a fever of unknown origin and progressive abdominal distension. Physical examination revealed generalized lymphadenopathy, multiple non-tender cutaneous nodules, hepatomegaly, splenomegaly and abdominal edema. An ...

journal_title：Oncology letters

authors： Song K,Li M

更新日期：2015-05-01 00:00:00

abstract：:Numerous studies concerning hepatic arterial infusion chemotherapy (HAIC) have been conducted by adopting regimens containing 5-fluorouracil (FU), with a favourable efficacy compared with conventional transcatheter arterial chemoembolisation (TACE) treatment; however, the detailed mechanism of HAIC remains unclear. Th...

journal_title：Oncology letters

authors： Gao J,Zhen R,Liao H,Zhuang W,Guo W

更新日期：2018-05-01 00:00:00

abstract：:Human papilloma virus (HPV) infection has previously been reported to be associated with TP53 and TP16 expression in Japanese and Taiwanese patients with lung cancer, but data for advanced non-small cell lung cancer (NSCLC) patients is limited. The present study examined the association between HPV infection and TP53 ...

journal_title：Oncology letters

authors： Li M,Zhang XL,Deng F,Qian LT,Meng SP,Shan WL,Wang BL

更新日期：2016-11-01 00:00:00

abstract：:The flavonoid compound scutellarin (Scu) is a traditional Chinese medicine used to treat a variety of diseases; however, the use of scutellarein (Scue), the hydrolysate of Scu, and its mechanisms of action in Alzheimer's disease (AD) have not been fully elucidated. In the present study, the effects of Scue on amyloid ...

journal_title：Oncology letters

authors： Huang XW,Xu Y,Sui X,Lin H,Xu JM,Han D,Ye DD,Lv GF,Liu YX,Qu XB,Duan MH

更新日期：2019-06-01 00:00:00

abstract：:The current case study aimed to explore the efficacy of a low-dose bevacizumab regimen in inhibiting tumor growth and minimizing adverse effects. A 55-year-old man with neurofibromatosis type 2 (NF2) suffered bilateral vestibular schwannomas (VS) measuring 5.25 and 2.54 cm3 on the left and right, respectively. His cap...

journal_title：Oncology letters

authors： Liu P,Yao Q,Li NA,Liu Y,Wang Y,Li M,Li Z,Li J,Li G

更新日期：2016-05-01 00:00:00

abstract：:Breast cancer is the most common malignant disease occurring in women. Conservative breast cancer surgery followed by radiation therapy is currently the standard treatment for this type of cancer. The majority of metastases occur within the scar, which initiated a series of studies. As a result, clinical trials aimed ...

journal_title：Oncology letters

authors： Zaleska K,Przybyła A,Kulcenty K,Wichtowski M,Mackiewicz A,Suchorska W,Murawa D

更新日期：2017-10-01 00:00:00

abstract：:Lonidamine, 6-Diazo-5-oxo-L-norleucine (DON) and orlistat are well known inhibitors of glycolysis, glutaminolysis and of de novo fatty acid synthesis, respectively. Although their antitumor effects have been explored in detail, the potential inhibition of the malignant metabolic phenotype and its influence on the expr...

journal_title：Oncology letters

authors： Schcolnik-Cabrera A,Dominguez-Gómez G,Chávez-Blanco A,Ramírez-Yautentzi M,Morales-Bárcenas R,Chávez-Díaz J,Taja-Chayeb L,Dueáas-González A

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to investigate the effect of dexmedetomidine (Dex) on the respiratory function during anesthesia induction in pediatric patients undergoing retinoblastoma (RB) resection. A total of 87 pediatric patients who underwent RB resection in Yidu Central Hospital of Weifang were recruited into this s...

journal_title：Oncology letters

authors： Rong X,Sun C,Zhang F,Zheng J

更新日期：2019-03-01 00:00:00