Abstract:
:The effect of intravenous enoximone on forearm venous circulation was studied in ten healthy volunteers (group A) and in ten patients with NYHA class III-IV congestive heart failure (group B). Distensibility of the forearm capacitance vessels was assessed from pressure-volume curves by venous occlusion plethysmography using a mercury-in-rubber strain gauge. Three recordings each at 3-min intervals were obtained before the infusion and again 20 min after completion of the infusion. Venous volume changes (VV) at congesting pressures of 10, 20, and 30 mmHg before and after enoximone were compared. Forearm muscle blood flow was also measured by venous occlusion plethysmography; electrocardiogram, heart rate, and cuff blood pressure were recorded throughout. Enoximone at a dose of 1 mg/kg body weight was infused over 10 min through a peripheral vein in group A and via a central line in group B. In group A, the effect of the injection vehicle was also assessed. VV10, VV20, and VV30 did not differ from baseline values after enoximone in both groups A and B. The vehicle caused a small but significant degree of venoconstriction in group A (VV20, 2.64 +/- 0.9 to 2.48 +/- 0.83 ml/100 ml, P less than 0.05; VV30, 3.47 +/- 1.27 to 3.33 +/- 1.20 ml/100 ml, P less than 0.05), which could be explained by an acute response to local pain from the infusion. This effect was not evident following enoximone, perhaps as a result of its counterbalancing vasodilating action to venoconstriction induced by acute pain.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Heart Vesselsjournal_title
Heart and vesselsauthors
Branzi A,Berardi C,Ferretti RM,Beato E,Magnani G,Melandri G,Zannoli R,Magnani Bdoi
10.1007/BF02058791subject
Has Abstractpub_date
1987-01-01 00:00:00pages
146-51issue
3eissn
0910-8327issn
1615-2573journal_volume
3pub_type
杂志文章abstract::Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) resulted in different degrees of damage to the heart muscle, and yet, when factors related to in-hospital outcomes were examined, these two subsets were often lumped together as non-STelevation acute coronary syndrome. Therefore, we investigated ...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
doi:10.1007/s00380-008-1141-y
更新日期:2009-11-01 00:00:00
abstract::An excess of thyroid hormone is known to produce cardiac dysfunction and failure, i.e., thyrotoxic heart. We studied the protective effect of coenzyme Q10 (CoQ10) on the thyrotoxic heart in 29 rabbits. A group treated with 1-thyroxine sodium salt (T4; 167 micrograms/kg) for 3 weeks showed marked decreases in the myoca...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058524
更新日期:1987-01-01 00:00:00
abstract::The clinical and immunological follow-up of a 38-year-old female patient with hypereosinophilic syndrome and classical cardiac involvement, but without demonstrable degranulation of eosinophils and lacking binding of a specific antibody for activated eosinophils, is presented. Instead, the patient demonstrated all the...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058696
更新日期:1990-01-01 00:00:00
abstract::Acute kidney injury (AKI) is a common complication after coronary angiography. Early biomarkers of this disease are needed since increase in serum creatinine levels is a late marker. To assess the usefulness of urinary kidney injury molecule-1 (uKIM-1), neutrophil gelatinase-associated lipocalin (uNGAL) and liver-type...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-014-0538-z
更新日期:2015-11-01 00:00:00
abstract::Mitral valve morphology after mitral valve surgery affects postoperative intraventricular flow patterns and long-term cardiac performance. We visualized ventricular flow by echocardiography vector flow mapping (VFM) to reveal the impact of different mitral valve procedures. Eleven cases of mechanical mitral valve repl...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-0967-6
更新日期:2017-09-01 00:00:00
abstract::The vascular responses to 5-hydroxytrypamine (5-HT), 5-carboxamidotryptamine (5-CT, a selective 5-HT1-like receptor agonist), alpha-methyl-5-HT (alpha-M-5-HT, a relatively selective 5-HT2 receptor agonist), noradrenaline (NA), and KCl were examined in isolated, cannulated, and perfused canine common carotid arterial p...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01745103
更新日期:1994-01-01 00:00:00
abstract::Flow-mediated dilation (FMD) is a widely used tool to investigate endothelial function. However, FMD assessment may cause mechanical damage to the arterial endothelium. In this study we investigated the effect of FMD assessment on endothelial function. We studied 20 healthy subjects (26 ± 6 years; 12 males). FMD was a...
journal_title:Heart and vessels
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00380-010-0087-z
更新日期:2011-09-01 00:00:00
abstract::Myocardial fibrosis and microvascular dysfunction are key determinants of outcome in heart failure (HF); we examined their relationship in patients with HF. Our study included 61 consecutive patients with HF but without coronary stenosis. All underwent gadolinium-enhanced cardiac magnetic resonance to evaluate late ga...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-016-0816-z
更新日期:2016-12-01 00:00:00
abstract::Late-acquired stent malapposition (LASM) is a common finding after sirolimus-eluting stent (SES) implantation and may be the cause for late stent thrombosis. Inflammation may play a pivotal role in LASM just as it plays in stent restenosis. We have therefore investigated seven polymorphisms involved in inflammatory pr...
journal_title:Heart and vessels
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00380-010-0046-8
更新日期:2011-05-01 00:00:00
abstract::Hyperuricemia is known to be associated with adverse outcomes in cardiovascular intensive care patients, but its mechanisms are unknown. A total of 569 emergency department patients were prospectively analyzed and assigned to intensive care (ICU group, n = 431) or other departments (n = 138). Uric acid (UA) levels wer...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-020-01608-x
更新日期:2020-10-01 00:00:00
abstract::Aortic dissection is a life-threatening cardiovascular disease with high in-hospital mortality. However, the risk factors of aortic dissection have not been fully elucidated. Obstructive sleep apnea (OSA) has been increasingly recognized as an independent cardiovascular risk factor. Among the underlying mechanisms to ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-011-0149-x
更新日期:2012-05-01 00:00:00
abstract::Two-dimensional echocardiographic measurements of the right and left ventricles from the parasternal long-axis and apical four-chamber views and an estimated right ventricular-left ventricular dimensional ratio were obtained in 173 normal subjects, ranging from 1 day to 15 years of age. The end-diastolic dimensions of...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058684
更新日期:1988-01-01 00:00:00
abstract::Balneotherapy has been shown to reduce systemic blood pressure in healthy volunteers. Hyperthermia might ameliorate the inflammatory status in heart failure through improving cardiac function. The purpose of this study was to examine the beneficial effects of balneotherapy in patients with chronic heart failure (CHF)....
journal_title:Heart and vessels
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00380-011-0220-7
更新日期:2013-03-01 00:00:00
abstract::Early and long-term outcomes in elderly patients who underwent isolated aortic valve replacement (iAVR) are well defined. Conflicting data exist in elderly patients who underwent AVR plus coronary artery bypass grafting (CABG). We sought to evaluate the early and long-term outcomes of combined AVR + CABG in patients o...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-019-01519-6
更新日期:2020-04-01 00:00:00
abstract::Peripartum cardiomyopathy (PPCM) is a rare but life-threatening cardiac disorder characterized by maternal systolic heart failure. Although PPCM is a major cause of maternal mortality, little is known about the acute-phase management of PPCM in real-world clinical settings. We retrospectively identified patients hospi...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-0958-7
更新日期:2017-08-01 00:00:00
abstract::Intracellular Na(+) ([Na(+)](i)) regulation plays a crucial role in the structural, mechanical, and electrical properties of myocardium. It is assumed that the [Na(+)](i) handling system may differ not only between normal and diseased hearts but also regionally within a heart. To gain new insight concerning disease- a...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-008-1071-8
更新日期:2009-01-01 00:00:00
abstract::The timing and amplitude of reflected arterial waves in the ascending aorta were studied by analysis of the aortic pressure waveform and were compared with those derived using wave intensity analysis. Wave intensity analysis considers aortic pressure changes to be the result of forward and backward wavelets carrying e...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01747827
更新日期:1998-01-01 00:00:00
abstract::In the present study we examined the action of native and oxidized low-density lipoproteins (LDL) on coronary vascular and cardiac function and ultrastructure in rat hearts perfused isovolumically in the Langendorff mode. Responses of the coronary resistance vessels to the endothelium-dependent vasodilator, histamine,...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01744904
更新日期:1995-01-01 00:00:00
abstract::Drug-eluting stents reduce restenosis due to neointimal growth suppression. Considering long-term outcomes, it is both difficult and important to predict drug-eluting stent restenosis. Thus, this study was designed to examine the utility of myocardial fractional flow reserve (FFR) as a predictor of sirolimus-eluting s...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-010-0105-1
更新日期:2011-11-01 00:00:00
abstract::The use of cine-computed tomography scanning is described in evaluating cardiac function in a patient with a bileaflet mitral valve prosthesis (St. Jude medical valve) and in a second patient with both mitral and aortic bileaflet prostheses. Both biventricular and prosthesis function were assessed successfully. ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058316
更新日期:1987-01-01 00:00:00
abstract::Therapeutic devices for acute myocardial infarction (AMI) have evolved dramatically in recent years. However, the impact of the Killip classification of AMI outcomes in patients undergoing aggressive percutaneous coronary intervention remains unclear. We performed a 10-year retrospective review of 2062 patients diagno...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-1017-0
更新日期:2017-12-01 00:00:00
abstract::Recently, the importance of central blood pressure for cardiovascular risk stratification has been emphasized. Accordingly, the differences in peak systolic and bottom diastolic pressures between the ascending aorta and the brachial artery should be clarified. Study subjects consisted of 82 consecutive patients with s...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-007-0998-5
更新日期:2007-11-01 00:00:00
abstract::The hydrostatic pressure (perfusion pressure) of the isovolumic isolated perfused rat heart regulated the hydrodynamics (water movement) of the myocardium. An abrupt (10 s) decrease in hydrostatic pressure caused an immediate decrease in oxygen consumption, left ventricular developed pressure, and wall thickness. Wall...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058424
更新日期:1988-01-01 00:00:00
abstract::Vector flow mapping (VFM) is a novel echocardiographic technology that shows blood flow vectors and vortexes, enabled the hydrokinetic evaluation of hemodynamics within the left ventricle. VFM provides several unique parameters: circulation, vorticity, vortex area, and energy loss. The present study aims to reveal a r...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-1093-1
更新日期:2018-05-01 00:00:00
abstract::Eicosapentaenoic acid (EPA) has antiarrhythmic effects. The J-wave on an electrocardiogram is associated with a high incidence of ventricular tachycardia/fibrillation (VT/VF). We evaluated relationships between EPA and J-waves, and their involvement in the occurrence of VT/VF in acute myocardial infarction (AMI). Two ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-013-0435-x
更新日期:2014-11-01 00:00:00
abstract::Independent no-reflow predictors should be evaluated in female patients with ST-segment elevation acute myocardial infarction (STEMI) and successfully treated with primary percutaneous coronary intervention (PPCI) in the current interventional equipment and techniques, thus to be constructed a no-reflow predicting mod...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
doi:10.1007/s00380-011-0144-2
更新日期:2012-05-01 00:00:00
abstract::The purpose of this study was to evaluate the surgical results of papillary muscle approximation (PMA) and papillary muscle relocation (PMR) for functional mitral regurgitation (FMR) and to compare the effects of both procedures on the change in mitral regurgitation (MR) and echocardiogram parameters associated with t...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-1038-8
更新日期:2018-01-01 00:00:00
abstract::Activation of mineralocorticoid receptor antagonists (MRAs) is cardioprotective; however, this property is lost upon blockade or inactivation of adenosine (ADO) receptor A2b. In this study, we investigated whether the effects of MRAs are mediated by an interaction between cardioprotective ADO receptors A1 and A3. Spir...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-019-01542-7
更新日期:2020-05-01 00:00:00
abstract::Cardiogenic shock frequently leads to death even with intensive treatment. Although the leading cause of cardiogenic shock is acute coronary syndrome (ACS), the clinical characteristics and the prognosis of ACS with cardiogenic shock in the present era still remain to be elucidated. We analyzed clinical characteristic...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
doi:10.1007/s00380-019-01354-9
更新日期:2019-08-01 00:00:00
abstract::Blood traces tortuous paths of flow through the heart. We postulate that momentum changes associated with direction changes optimize dynamic coupling between ventricular and atrial function, particularly on exercise. Traces of pulsed Doppler mitral flow and M-mode long-axis mitral ring movement were recorded before an...
journal_title:Heart and vessels
pub_type: 临床试验,杂志文章
doi:10.1007/BF02767127
更新日期:1997-01-01 00:00:00