Abstract：
INTRODUCTION:Muscle force production is usually impaired in people with spinal cord injury (SCI). The use of high-intensity neuromuscular electrical stimulation (NMES) strength training can help promote metabolically active lean muscle mass and, thus, increase muscle mass and improve physical health and quality of life (QoL). Nonetheless, NMES is usually used at low-stimulation intensities, and there is limited evidence on the effects of high-intensity NMES strength training into improving muscle force and mass, symptoms of spasticity, or physical health and QoL in people with SCI. METHODS:Five individuals with chronic SCI completed five 10-repetition sets of high-intensity knee extension NMES strength training sessions for 12 wk in both quadriceps muscles. Quadriceps femoris (QF) knee extensor torque was measured on a dynamometer, and cross-sectional area (CSAQF) was measured with extended field-of-view ultrasonography. Venous blood samples were collected for blood lipid profiling and C-reactive protein analyses. The Spinal Cord Injury Spasticity Evaluation Tool was used to assess symptoms of spasticity, and the QoL index SCI version III was used for QoL measures. RESULTS:QF tetanic knee extensor torque increased on average by 35% (2%-92%), and CSAQF increased by 47% (14%-145%). A significant increase in the HDL/LDL cholesterol ratio (P < 0.001) and a mean significant improvement of 4.8% ± 2.3% (absolute value = 0.26) in the Spinal Cord Injury Spasticity Evaluation Tool score was observed, whereas QoL showed a near-significant improvement in the health and functioning domain (15.0 ± 4.2 and 17.3 ± 5.1; P = 0.07). CONCLUSIONS:High-intensity NMES strength training in people with SCI may improve muscle strength, mass, physical health, and QoL. However, replication of these results is necessary before clinical implementation.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Bochkezanian V,Newton RU,Trajano GS,Blazevich AJdoi
10.1249/MSS.0000000000001637subject
Has Abstractpub_date
2018-09-01 00:00:00pages
1733-1739issue
9eissn
0195-9131issn
1530-0315journal_volume
50pub_type
杂志文章abstract：:This study examined the association between aerobic, caloric exercise expenditure and life status (living vs deceased) as well as the prevalence rates of hypertension (HBP) and cardiovascular disease (CVD) in former male athletes (ATH) and non-athletes (N-ATH). The initial survey for this study was done in 1952. Follo...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-199012000-00002
更新日期：1990-12-01 00:00:00
abstract：:A 19-yr-old college football player presents with a 1.5-yr history of right shoulder pain and associated easy fatigability of the right arm. The history is significant for an automobile accident 3 yr prior to presentation in which the right shoulder struck the dashboard of the car. An extensive workup proved unremarka...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The two goals of this study were: 1) to establish a stimulation pattern which would drive the gastrocnemius-plantaris muscle of the dog, in situ, to maximal work rate, W, and 2) to determine whether the surgical isolation of the circulation of this muscle, necessary to measure the muscle flow, Q, reduced the muscle's ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-198810001-00003
更新日期：1988-10-01 00:00:00
abstract：:Hydrostatic weighing (HW) was performed at residual volume (RV) and total lung capacity without head submersion (TLCNS). Ninety-five males (25.6 +/- 4.9 yr) and 87 females (22.6 +/- 5.2 yr) were studied at two laboratory sites using identical protocols. Twenty males and 20 females were separated from the original grou...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1249/00005768-198802000-00010
更新日期：1988-02-01 00:00:00
abstract：PURPOSE:To better understand the mechanical behavior of healing skeletal muscle; specifically the tissue's response after acute eccentric stretch injury. METHODS:Rabbit tibialis anterior (TA) muscle tendon units were subjected to an in vivo single stretch (eccentric) injury and mechanically evaluated (constant rate el...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000084423.39529.C5
更新日期：2003-09-01 00:00:00
abstract：INTRODUCTION:It is well established that hemodynamic dysfunction, resulting in diminished upper-extremity work capacity, occurs in persons with spinal cord injury (SCI) as compared with those who are nondisabled (ND). Although it has been shown that persons with paraplegia display higher values of heart rate (HR) with ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200209000-00001
更新日期：2002-09-01 00:00:00
abstract：:The association of physical activity to the initiation of health risk behaviors was examined in a 3-yr prospective study of a population-based cohort of 1245 adolescents aged 12-16 yr. Four hundred thirty-seven students (35% of the cohort) were identified at baseline via self-report survey as never having smoked cigar...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：INTRODUCTION:The development of chronic ankle instability (CAI) is the primary residual deficit after ankle joint sprain. It has been proposed that CAI is characterized by two entities, namely, mechanical instability and functional instability. Each of these entities in turn is composed of various insufficiencies. Rese...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/MSS.0b013e3181de7a8a
更新日期：2010-11-01 00:00:00
abstract：INTRODUCTION:Although both humans and quadrupeds frequently coordinate breathing and limb movement during running, early studies in humans focused on how increased breathing flexibility in humans allowed for relaxed or even transient coordination during locomotion. This difference was used to explain why quadrupeds had...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318248d907
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:This study aimed to examine the effect of altering osmolality or adding sodium alginate and pectin to a concentrated carbohydrate (CHO) beverage on gastric-emptying (GE) rate. METHODS:Boluses (500 mL) of three drinks were instilled double blind in eight healthy men while seated, GE was measured using the doubl...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002301
更新日期：2020-08-01 00:00:00
abstract：:The availability of choline, the precurser of the neurotransmitter, acetylcholine, in the diet is sufficient to provide the body's requirements under normal conditions. However, preliminary evidence indicates that depletion of choline may limit performance, while oral supplementation may delay fatigue during prolonged...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-05-01 00:00:00
abstract：PURPOSE:To study the ventilatory effects of closely monitored cycle ergometer conditioning (HR target, 145-150 beats x min(-1); 25 min/session; three sessions per week) during the second and third pregnancy trimesters (TMs) in healthy human pregnancy. METHODS:Subjects were 27 previously sedentary pregnant women (exerc...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199801000-00004
更新日期：1998-01-01 00:00:00
abstract：:Twelve 9- to 12-year-old children (6 boys, 6 girls) performed four exercise-in-heat (35 degrees C, 45% RH) trials which differed in the composition of the fluids they drank. In each trial, subjects cycled for one 20-min and two 15-min bouts at 50% peak VO2 with 10-min rest periods in between. In a fourth bout, they cy...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:We compared the aortic-cardiac baroreflex sensitivity in eight average fit (AF: VO2max = 44.7 +/- 1.3 ml.kg-1 x min-1) and seven high fit (HF: VO2max = 64.1 +/- 1.7 ml.min-1 x kg-1) healthy young men during hypotension elicited by steady state sodium nitroprusside (SN) infusion. During SN mean arterial pressure (MAP) ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：PURPOSE:Obesity in adolescence increases the risk for early adult cardiovascular disease. We recently showed that 6 months of diet, exercise, and metformin resulted in reductions in adiposity and that diet/exercise alone reduced proinflammatory factors and intrahepatic fat in pubertal children with uncomplicated obesit...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31823cef5e
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:The purpose of this study was to examine the relative association of physical activity, cardiorespiratory fitness (CRF), and adiposity with C-reactive protein (CRP) in prepubescent children. METHODS:Forty-five prepubescent children (age = 9.4 ± 1.6 yr; 26 boys) were assessed for adiposity (percent fat) via dua...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181e0355e
更新日期：2010-11-01 00:00:00
abstract：INTRODUCTION:High-intensity endurance training can elicit profound cardiac adaptations; however, the current evidence as to its impact on the proximal aorta is limited. The purpose of this study was to investigate the morphological and functional characteristics of the proximal aorta in endurance athletes. METHODS:Fif...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002508
更新日期：2020-08-31 00:00:00
abstract：PURPOSE:Sleep is considered essential for muscle recovery, mainly due to its effect on hormone secretion. Total sleep deprivation or restriction is known to alter not only blood hormones but also cytokines that might be related to skeletal muscle recovery. This study aimed to evaluate whether total sleep deprivation af...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000002137
更新日期：2020-02-01 00:00:00
abstract：:Energy expenditure during bicycling on flat terrain depends predominantly on air resistance, which is a function of total frontal area (bicycle and rider), coefficient of drag, and air speed. Body position on the bicycle may affect energy expenditure by altering either frontal area or coefficient of drag. In this stud...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:The immune response was assessed in 13 competitive bodybuilders self-administering anabolic-androgenic steroids and ten competitive bodybuilders not administering these drugs. Laboratory assessment included the number and relative distribution of T-cells, T-helper/inducer cells, T-cytotoxic/suppressor cells, activated...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1989-08-01 00:00:00
abstract：PURPOSE:The main purpose of the present study was to measure the total oxygen consumed, accumulation of blood metabolites, and performance during alternating intensity exercise before and after a period of creatine (Cr) loading in well-trained humans. METHODS:Fourteen males were randomly assigned to two groups of seve...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005768-200002000-00018
更新日期：2000-02-01 00:00:00
abstract：:Physiological variables must often be scaled for body size differences to permit meaningful comparisons between subjects or groups. This study aimed to determine the proper relationship between body dimensions and left ventricular mass (LVM) via allometric scaling (AS) in 142 subjects (78 males, 64 females; ages 18-40...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199702000-00003
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:This study was conducted to test the hypothesis of autonomic imbalance in overtrained athletes during sleep and after awakening with analyses of heart rate variability (HRV) and nocturnal urine stress hormones. METHODS:We examined 12 athletes diagnosed to be severely overtrained (OA, 6 men and 6 women, mean ag...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000184631.27641.b5
更新日期：2006-02-01 00:00:00
abstract：PURPOSE:Investigate development of specific performance adaptions and hormonal responses every fourth week during a 12-wk high-intensity training (HIT) period in groups with different interval-training prescriptions. METHODS:Sixty-three well-trained cyclists performing a 12-wk intervention consisting of two to three H...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,多中心研究
doi：10.1249/MSS.0000000000001214
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:Elevated rates of cardiometabolic diseases have been observed in former American football players. The current study sought to determine whether change in body mass index (ΔBMI) after retirement influences the prevalence of CHD, diabetes, or high blood pressure (HBP) in former professional football players. ME...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001492
更新日期：2018-04-01 00:00:00
abstract：:To determine the factors in daily physical activity that influence the mineral density of the calcaneus, we recorded walking steps and the type and duration of exercise in 43 healthy 26-to 51-yr-old men. Areal (g.cm-2) calcaneal bone mineral density (CBMD) was measured by single energy x-ray densitometry (SXA, Osteon,...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：PURPOSE:To evaluate the effects of a 12-wk period of aquatic training and subsequent detraining on health-related quality of life (HRQOL) and physical fitness in females with fibromyalgia. METHODS:Thirty-four females with fibromyalgia were randomly assigned into two groups: an exercise group, who exercised for 60 min ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/01.mss.0b0138059aec4
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:The objective of this study is to test the feasibility and impact of a 10-wk after-school exercise program for children with attention deficit hyperactivity disorder and/or disruptive behavior disorders living in an urban poor community. METHODS:Children were randomized to an exercise program (n = 19) or a com...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000000891
更新日期：2016-07-01 00:00:00
abstract：PURPOSE:Ipratropium bromide (IB) has been used to prevent exercise-induced bronchoconstriction (EIB), but its effect varies among individuals. We hypothesized that such variability may reflect individual differences in vagal activity (VA), and therefore determined whether a correlation exists between VA and the effect ...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1249/01.mss.0000155436.31581.90
更新日期：2005-03-01 00:00:00
abstract：:The relationships between physical activity, physical fitness, and coronary heart disease risk factors measured in a large community sample were evaluated. Self-reported physical activity using a single question, maximal oxygen consumption estimates derived from the Pawtucket Heart Health Step Test, blood pressure, no...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
