Abstract：
PURPOSE:The main purpose of the present study was to measure the total oxygen consumed, accumulation of blood metabolites, and performance during alternating intensity exercise before and after a period of creatine (Cr) loading in well-trained humans. METHODS:Fourteen males were randomly assigned to two groups of seven males and were tested before and after 5 d of placebo (PL) or Cr monohydrate (CR) loading (20 g x d(-1)). Oxygen uptake was measured using a breath-by-breath system during bicycle exercise alternating every 3 min between bouts at 30%(-30%) and 90% (-90%) of the maximal power output to exhaustion. Blood samples were also obtained at rest, before the end of each cycling load, at exhaustion, and 5-min postexercise. RESULTS:The oxygen consumed during 1-90% (5.08 +/- 0.39 L) and 2-90% (5.32 +/- 0.30 L) was larger after CR (5.67 +/- 0.34 and 5.78 +/- 0.35 L, P < 0.01 and P < 0.05, respectively). Blood ammonia accumulation at the end of 1-90% (23.1 +/- 6.5 micromol x L(-1)) and 3-30% (64.7 +/- 15.2 micromol x L(-1)) was lower after CR (P < 0.05), whereas plasma uric acid accumulation was lower at exhaustion (P < 0.05) and 5-min postexercise (P < 0.01). Time to exhaustion increased (P < 0.05) from 29.9 +/- 3.8 to 36.5 +/- 5.7 min after CR, whereas it remained the same after PL. CONCLUSIONS:The results indicate that Cr feeding increases the capacity of human muscle to perform work during alternating intensity contraction, possibly as a consequence of increased aerobic phosphorylation and flux through the creatine kinase system.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Rico-Sanz J,Mendez Marco MTdoi
10.1097/00005768-200002000-00018subject
Has Abstractpub_date
2000-02-01 00:00:00pages
379-85issue
2eissn
0195-9131issn
1530-0315journal_volume
32pub_type
临床试验,杂志文章,随机对照试验abstract：:Relatively few studies have assessed the prospective relationship of sedentary lifestyle and coronary heart disease (CHD) in women. We performed a nested case-control study, identifying 50 cases of acute CHD in women and 150 age-matched controls. Risk factors including sedentary lifestyle, cigarette smoking, hypertens...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：PURPOSE:Overtraining is primarily related to sustained high load training, often coupled with other stressors. Studies in animal models have suggested that unremittingly heavy training (monotonous training) may increase the likelihood of developing overtraining syndrome. The purpose of this study was to extend our prel...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199807000-00023
更新日期：1998-07-01 00:00:00
abstract：UNLABELLED:Exercise increases methionine metabolism, which also increases its amino acid metabolic intermediate, homocysteine (Hcy). High Hcy levels increase cardiovascular disease (CVD) risk, whereas B-vitamins (folate, vitamins B6, and B12) can reduce Hcy. Research exploring the relationship between exercise and Hcy ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31817f36f9
更新日期：2008-11-01 00:00:00
abstract：:Cardiorespiratory characteristics, relative body fat, grip strength and selected skinfolds, circumferences and bone diameters were determined in 25 males and 25 females (31--55 yr) whose exclusive mode of regular exercise was tennis (9.7--11.1 hr/wk). Mean resting heart rates were 54 beats/min for the males and 61 bea...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:The degree of parasympathetic control of resting heart rate (PC) was assessed by measurement of variation in heart period (VHP) during cardiopulmonary synchronization of respiration. Respiratory period was arbitrarily preset and standardized at 7 heart beats (3 beats inspiration, 4 beats expiration). The mathematical ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-198508000-00008
更新日期：1985-08-01 00:00:00
abstract：UNLABELLED:Environmental heat stress degrades aerobic performance; however, little research has focused on performance when the selected task elicits modest elevations in core body temperature (<38.5 degrees C). PURPOSE:To determine the effect of environmental heat stress, with modest hyperthermia, on aerobic performa...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e3181adb9fb
更新日期：2010-01-01 00:00:00
abstract：:Data obtained from 16-mm film of world caliber Olympic weight lifters performing at major competitions were analyzed to study energy changes during body segment and barbell movements, energy transfer to the barbell, and energy transfer between segments during the lifting movements contested. Determination of barbell a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：PURPOSE:High internal stress is considered to be a possible cause of heel-pad problems. External biomechanical measurements are used to attempt to understand the causes of heel pain. However, internal stress cannot be measured experimentally. Therefore, the purpose of this study was to quantify the relationship between...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：PURPOSE:We aimed to evaluate in a longitudinal study the effect of intensive training on cardiac autonomic control in athletes using 24-h heart rate variability analysis. METHODS:Time and frequency domain measures of heart rate variability were calculated from 24-h Holter monitoring in 15 high level bicyclists (mean a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199805000-00008
更新日期：1998-05-01 00:00:00
abstract：:Thirty-eight athletes with unilateral patellar tendinopathy (17 with a tendinopathy of the main body of the tendon, and 21 with an insertional tendinopathy) underwent ultrasound-guided multiple percutaneous longitudinal tenotomy under local anaesthetic infiltration after failure of conservative management. Thirty-four...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199911000-00003
更新日期：1999-11-01 00:00:00
abstract：PURPOSE:The primary study aim was to evaluate associations of estimated weekly minutes of moderate-to-vigorous-intensity exercise from self-reports of the telephone-administered 7-Day Physical Activity Recall (7-Day PAR) with data captured by the RT3 triaxial accelerometer. METHODS:This investigation was undertaken as...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e3181984fa8
更新日期：2009-06-01 00:00:00
abstract：:Although onset and maximal claudication pain are attained sooner as exercise intensity is increased, it is unclear whether dissipation of pain during recovery is altered. Thus, this study examined whether walking at gradually higher intensity would prolong the time needed for claudication pain to dissipate during reco...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
abstract：INTRODUCTION:The quadriceps avoidance gait pattern may not be as common in ACL deficient (ACLd) gait as previously described. PURPOSE:The purpose of this study was to investigate the existence of the quadriceps avoidance pattern in ACL deficient patients and to further identify gait compensations that may exist in thi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000135797.09291.71
更新日期：2004-08-01 00:00:00
abstract：PURPOSE:To provide evidence that lower-extremity muscle activity during running is tuned in response to the loading rate of the impact forces at heel-strike. METHODS:Six runners ran two 30-min trials per week for 4 wk. The trials tested two shoes which differed only in the material hardness of the midsole. The shoes w...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-200209000-00021
更新日期：2002-09-01 00:00:00
abstract：UNLABELLED:Accurate assessment of physical activity (PA) is necessary to identify the sedentary older individual who is in need of activity intervention. Activity monitors are quite popular, although it has been suggested that they are less accurate at slow gait speeds. PURPOSE:To examine the accuracy of the three act...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/mss.0b013e318158b504
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:Although independent relationships between sitting behaviors (mainly television viewing) and health outcomes have been reported, few studies have examined the measurement properties of self-report sitting questions. This study assessed gender-specific test-retest reliability and validity of a questionnaire that...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181c5ec18
更新日期：2010-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to investigate the influence of different cycling cadences on metabolic and kinematic parameters during subsequent running. METHODS:Eight triathletes performed two incremental tests (running and cycling) to determine maximal oxygen uptake (VO2max) and ventilatory threshold (VT) va...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005768-200203000-00022
更新日期：2002-03-01 00:00:00
abstract：:The cell-to-cell lactate shuttle was introduced in 1984 and has been repeatedly supported by studies using a variety of experimental approaches. Because of its large mass and metabolic capacity, skeletal muscle is probably the major component of the lactate shuttle in terms of both production and consumption. Muscles ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/MSS.0b013e31815fa580
更新日期：2008-03-01 00:00:00
abstract：:Influence of post-surgery time after cardiac transplantation on exercise responses. Med. Sci. Sports Exerc., Vol. 28, No. 2, pp. 171-175, 1996. To test the hypothesis that exercise response changes with time after cardiac transplantation, we investigated the cardiorespiratory responses of nine orthotopic heart transpl...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-199602000-00003
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVE:To examine the effect of an increase in roller ski rolling resistance on the physiological and upper body demands of roller skiing with the V2-alternate technique. METHODS:Nine highly skilled cross-country skiers roller skied at three paced speeds on a flat oval loop using roller skis with high (HiR) and low...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199805000-00018
更新日期：1998-05-01 00:00:00
abstract：PURPOSE:Considering the different loading and training characteristics of the sports practiced during growth, it is important to specify and categorize the bone and soft tissue adaptations in adolescent athletes. This study aimed to categorize 10 different loading sports and a nonsport group and identify the difference...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002420
更新日期：2020-12-01 00:00:00
abstract：INTRODUCTION:Dementia caregivers have an increased risk of cardiovascular disease, and it is possible that metabolic disturbances contribute to this risk. Regular physical exercise reduces cardiometabolic risk, but caregivers may have less opportunity to engage in such activity. We hypothesized that regular physical ac...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181e6d478
更新日期：2011-01-01 00:00:00
abstract：PURPOSE:Increased serum testosterone (TST) occurs in response to resistance exercise and is associated with increased muscle mass. However, the effects of elevated TST and sequential resistance exercise bouts on androgen receptor (AR) expression in humans are not well known. This study examined three sequential bouts o...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1249/01.mss.0000139795.83030.d1
更新日期：2004-09-01 00:00:00
abstract：PURPOSE:Lateral knee osteoarthritis (OA) is common after anterior cruciate ligament reconstruction (ACLR), yet gait characteristics associated with lateral knee OA after ACLR are not well understood. This cross-sectional study aimed to compare knee, trunk, pelvis, hip, and ankle kinematics and moments between people wi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000671
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:The purpose of this study was to examine the ability of the SenseWear Pro2 Armband (SWA) to accurately assess energy expenditure in free-living overweight or obese children during a 2-wk period by comparison with energy expenditure measured using the doubly labeled water (DLW) method. A second aim was to examin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181c84091
更新日期：2010-06-01 00:00:00
abstract：INTRODUCTION:Cardiac magnetic resonance (CMR) late gadolinium enhancement (LGE) and T1 mapping techniques enable the quantification of focal and diffuse myocardial LGE, respectively. Studies have shown evidence of fibrosis in middle-age athletes, but not relative to physically active (PA) adults who perform recommended...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002411
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:We investigated ethnic differences in areal bone mineral density (aBMD; g x cm(-2)) and its determinants at two levels of maturity in Asian- and Caucasian-Canadian girls. METHODS:Participants were 131 Asian (26 Tanner breast stage I (aTI) and 30 Tanner II (aTII)), and Caucasian (30 Tanner I (cTI) and 45 Tanner...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200111000-00004
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:Strain magnitude is known to be a primary determinant of the osteogenic response to loading. However, whether bone adaptation to muscle loading is determined primarily by load magnitude is unclear. The purpose of this study was to determine the contribution of load magnitude from muscle action on the site-speci...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199909000-00009
更新日期：1999-09-01 00:00:00
abstract：:Previous research on catecholamine (CA) response to exercise has linked heightened adiposity to a hypostress syndrome. In the present study a cognitive/psychomotor stressor was employed to determine whether this association exists during less metabolically challenging tasks. Moreover, because stress is manifested in a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：PURPOSE:Previous studies have suggested that higher levels of physical activity may lower lung cancer risk; however, few prospective studies have evaluated lung cancer mortality in relation to cardiorespiratory fitness (CRF), an objective marker of recent physical activity habits. METHODS:Thirty-eight thousand men, ag...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181c47b65
更新日期：2010-05-01 00:00:00
