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Posttransplant encapsulating peritoneal sclerosis, long-term success with everolimus and low-dose CNI: a case report.

Abstract：

:Encapsulating peritoneal sclerosis is a serious complication of peritoneal dialysis and can occur even after transplant. The gut is partially or totally enveloped by a thick fibrous membrane that leads to the formation of multiple sections containing intestinal loops contracted and reduced in volume. Exacerbation after renal transplantation is a very rare but sometimes dramatic condition. We report a patient who developed intestinal obstruction due to encapsulating peritoneal sclerosis 1 year after a deceased-donor kidney transplant. Treatment included laparotomy, small-bowel lengthening by release of adhesions, and high doses of corticosteroids. The patient received immunosuppressive therapy with a combination of low-dose cyclosporine, everolimus, and prednisone, unchanged except for a temporary steroid increase in the postoperative period. We report success with this combined surgical plus medical therapy, with no recurrence after 81 months of follow-up.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Romagnoli J,Pedroso JA,Salerno MP,Favi E,Spagnoletti G,Citterio F

doi

10.1016/j.transproceed.2014.07.060

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

2368-70

issue

7

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(14)00649-6

journal_volume

46

pub_type

杂志文章

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