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Update of the University of California at San Francisco experience with donor-specific blood transfusions.

Abstract：

:Prospective pretreatment with deliberate DST has afforded MLC reactive related donor-recipient pairs enhanced opportunity for successful transplantation. The sensitization rate in patients receiving DST prior to primary transplantation was 30%, but this sensitization has been generally specific and narrow-those patients developing a positive DSXM do not appear to be jeopardized regarding later cadaver transplantation. Graft survival rates in 86 recipients of kidneys from their blood donors are 95% (1-year) and 93% (2-year). This graft survival rate appears to outweigh the minimal risk of possible unfavorable sensitization. Potentially unsuccessful transplants in immunologically disparate related donor-recipient pairs can be avoided, and the transplants actually performed have enhanced prospects of success.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Salvatierra O Jr,Iwaki Y,Vincenti F,Amend W,Terasaki P,Garovoy M,Duca R,Hopper S,Feduska N

subject

Has Abstract

pub_date

1982-06-01 00:00:00

pages

363-6

issue

2

eissn

0041-1345

issn

1873-2623

journal_volume

14

pub_type

杂志文章

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