Abstract:
BACKGROUND:Allergic Broncho Pulmonary Aspergillosis (ABPA) is a rare disease characterized by an allergic inflammatory response to the colonization by aspergillus or other fungi in the airways. The aim was to study the clinical, radiological, and serological characteristics of patients of ABPA. MATERIALS AND METHODS:A prospective observational study of patients with breathlessness, chronic cough, blood eosinophilia, and infiltrates on chest X-ray were evaluated with serologic and allergic skin fungal tests using 15 common fungal antigens. Total of 24 patients were diagnosed as ABPA. RESULTS:Total 24 patients, 15 males (62%), 9 females (38%). Age range: 14-70 years, mean 49.13, standard deviation (SD) 14.12. Central bronchiectasis - sixteen patients, bronchocoele - one patient, consolidation - five patients, collapse with mucous plugging with areas of consolidation - three patients, one patient had bronchiectasis, consolidation with hemorrhagic pleural effusion. Fifty-eight percent of patients had received anti-tuberculosis medications prior to diagnosis. Serum total IgE varied from 340 to 18100 IU/mL. Two patients had IgE levels below 1,000 IU/mL. The mean decrease in Serum total IgE levels at the end of 1 month was 26.1% (range: 0.7-71.9%) and at the end of 2 months was 58.9% (range: 11.11-93.26%) (P value of 0.004). Two patients had skin sensitivity to fungal antigens other than aspergillus species. CONCLUSION:ABPA is a disease with varied clinical, radiological, and serological patterns. Serum IgE monitoring may be done at the end of 2 and 6 months. Further studies are required to simplify the diagnosis and treatment algorithms in resource-limited countries.
journal_name
Ann Thorac Medjournal_title
Annals of thoracic medicineauthors
Natarajan S,Subramanian Pdoi
10.4103/1817-1737.140130subject
Has Abstractpub_date
2014-10-01 00:00:00pages
216-20issue
4eissn
1817-1737issn
1998-3557pii
ATM-9-216journal_volume
9pub_type
杂志文章abstract:BACKGROUND:There is limited data about the performance of QuantiFERON-TB Gold (QFT-G) test in detecting latent tuberculosis infection (LTBI) in our region. We intended to determine the performance of QFT-G compared to conventional tuberculin skin test (TST) in detecting LTBI in HIV-positive individuals in Iran. METHOD...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.58959
更新日期:2010-01-01 00:00:00
abstract::The reported studies suggest a role for eosinophils in the pathogenesis of cough variant asthma. In the present study, the expired breath condensate level of hydrogen peroxide and pH were determined in patients with cough variant asthma and compared to subjects with classical asthma, with chronic cough nonasthmatic an...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.30357
更新日期:2007-01-01 00:00:00
abstract::Patient-ventilator asynchrony (PVA) is common in patients receiving noninvasive ventilation (NIV). This occurs primarily when the triggering and cycling-off of ventilatory assistance are not synchronized with the patient's inspiratory efforts and could result in increased work of breathing and niv failure. In general,...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/atm.ATM_24_19
更新日期:2020-01-01 00:00:00
abstract:STUDY OBJECTIVES:Obstructive sleep apnea (OSA) is common in adult populations. Accumulating data indicate that it is independently associated with a variety of cardiovascular diseases and has prognostic importance in affected cases. In this study, we aimed to evaluate coronary flow reserve (CFR) in patients with OSA an...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_195_16
更新日期:2017-10-01 00:00:00
abstract::We report a case of bronchial Dieulafoy's disease in the pediatric age. Angio-computed tomography scan and arteriography addressed us to diagnosis. Bronchial endoscopy with biopsy was avoided due to the high risk of developing a life-threatening hemorrhage. Transcatheter embolization of the bleeding bronchial artery w...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_163_20
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The IL-4 receptor alpha subunit (IL-4Rα), when associated with the common gamma chain receptor, or the IL-13Rα1 subunit, transduces signals to STAT6 in response to IL-4 and IL-13 stimulations. This results in a number of cell-specific responses including Th2 differentiation, lymphocyte proliferation and IgE ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.128849
更新日期:2014-04-01 00:00:00
abstract:INTRODUCTION:Right ventricular strain (RVS) in pulmonary embolism (PE) can be used to stratify risk and direct intervention. The clinical significance of computed tomography pulmonary angiogram (CTPA)-derived radiologic signs of RVS, however, remains incompletely characterized. We retrospectively analyzed a cohort of p...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_264_19
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Fiber-optic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) is a common procedure performed in immunocompromised patients with undiagnosed pulmonary pathology. Identifying patients with the highest potential diagnostic yield may help to avoid morbidity in patients unlikely to benefit from the procedur...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.114302
更新日期:2013-07-01 00:00:00
abstract::Pulmonary rehabilitation (PR) is an integral component of the comprehensive management plan of patients with chronic lung diseases by addressing their functional and psychological deficits. PR is generally recommended to symptomatic patients with chronic lung diseases who develop shortness of breath on their own pace ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/1817-1737.124408
更新日期:2014-01-01 00:00:00
abstract::The professional content of sleep medicine has grown significantly over the past few decades, warranting the recognition of sleep medicine as an independent specialty. Because the practice of sleep medicine has expanded in Saudi Arabia over the past few years, a national regulation system to license and ascertain the ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.105710
更新日期:2013-01-01 00:00:00
abstract::The Saudi Initiative for Asthma (SINA) provides up-to-date guidelines for healthcare workers managing patients with asthma. SINA was developed by a panel of Saudi experts with respectable academic backgrounds and long-standing experience in the field. SINA is founded on the latest available evidence, local literature,...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.56001
更新日期:2009-10-01 00:00:00
abstract:CONTEXT:Bronchoscopic intervention can provide immediate relief from suffocation and an opportunity for additional treatment in patients with malignant airway obstruction. However, few studies have specifically identified prognostic factors affecting the survival of advanced lung or esophageal cancer patients receiving...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.109818
更新日期:2013-04-01 00:00:00
abstract::Swyer-James-MacLeod (SJM) syndrome is a chronic, progressive lung disease as a result of infection and bronchial obstruction that ultimately leads to emphysema. It is associated with chronic cough, sputum production and recurrent chest infections and is occasionally seen in women of reproductive age. The radiological ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.37976
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Prolonged use of oral corticosteroids is a risk factor for osteoporosis. However, the effect of inhaled corticosteroids (ICS) on bone mineral density (BMD) of asthmatic patients remains controversial. OBJECTIVES:We aimed to determine the prevalence of osteopenia and osteoporosis in our patients with asthm...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.94522
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the association between epidermal growth factor receptor (EGFR) mutation and thyroid cancer in female patients with nonsmall-cell lung cancer (NSCLC). METHODS:In a retrospective study, we examined 835 female patients who were diagnosed with NSCLC and underwent an EGF...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.197774
更新日期:2017-01-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_15_17
更新日期:2017-07-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.134066
更新日期:2014-07-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.44783
更新日期:2009-01-01 00:00:00
abstract::Bronchiolitis obliterans organizing pneumonia (BOOP) was first described in the early 1980s as a clinicopathologic syndrome characterized symptomatically by subacute or chronic respiratory illness and histopathologically by the presence of granulation tissue in the bronchiolar lumen, alveolar ducts and some alveoli, a...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.39641
更新日期:2008-04-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.152450
更新日期:2015-04-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_286_20
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_147_18
更新日期:2018-10-01 00:00:00
abstract::Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia is associated with very high mortality. Though surgical evacuation of necrotic tissue is desirable in patients unresponsive to antimicrobial therapy, most patients are acutely ill precluding surgical intervention. We utilized a combinat...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.164298
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:For patients that are expected to survive for longer, the risk of complications combined with the need for more vacuum drainage bottles have become barriers to the placement of indwelling pleural catheter (IPC), since these could increase costs. OBJETIVES:The objective of the current article is to determine...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.160837
更新日期:2015-07-01 00:00:00
abstract::With increased exposure of patients to routine imaging, incidental benign intrathoracic masses are frequently recognized. Most have classical imaging features, which are pathognomonic for their benignity. The aim of this pictorial review is to educate the reader of radiological features of several types of intrathorac...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/1817-1737.160365
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Physicians may experience periods of acute sleep deprivation while on-call, in addition to baseline chronic sleep deprivation which may affect physicians' performance and patients' safety. The purpose of this study was to determine the effect of acute sleep deprivation due to working long on-ca...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.105715
更新日期:2013-01-01 00:00:00
abstract::Tracheobronchial obstruction along with compression of pulmonary vessels is a rare complication after stenting of aortic aneurysm. We present this rare situation in a young patient who underwent stenting of traumatic thoracic aortic aneurysm and developed this near fatal complication and also the conservative manageme...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.74275
更新日期:2011-01-01 00:00:00
abstract:AIMS:Flexible bronchoscopy is a common procedure performed in pulmonary medicine, critical care, and thoracic surgery. In this study, we aimed to assess the prevalence and predictors of anxiety in patients undergoing diagnostic bronchoscopy. METHODS:This is a prospective study conducted at King Abdulaziz University Ho...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_38_19
更新日期:2019-07-01 00:00:00
abstract::Pulmonary tumor thromboembolism is well described in literature especially in patients known to have cancer. We are presenting this report of a patient presenting with Acute Cor-pulmonale secondary to Occult Gastric carcinoma causing pulmonary tumor embolism. This is an unusual presentation of occult neoplasm. ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.36553
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:Gefitinib, a small molecule tyrosine kinase inhibitor, showed a substantial effect as a salvage treatment for patients with advanced non-small cell lung cancer (NSCLC) who had failed prior chemotherapy. Subsequent phase III trials in previously untreated patients have failed to demonstrate such benefit. It wa...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.65047
更新日期:2010-07-01 00:00:00