Bone mineral density in asthmatic patients on inhaled corticosteroids in a developing country.

Abstract:

INTRODUCTION:Prolonged use of oral corticosteroids is a risk factor for osteoporosis. However, the effect of inhaled corticosteroids (ICS) on bone mineral density (BMD) of asthmatic patients remains controversial. OBJECTIVES:We aimed to determine the prevalence of osteopenia and osteoporosis in our patients with asthma receiving ICSs for more than one year compared with patients who did not have asthma and to determine the risk factors for osteopenia and osteoporosis among the asthmatic patients. METHODS:This was a cross-sectional study conducted from August 2007 to July 2009. Asthmatic patients aged 18 years and older who had been on ICS for at least one year and a control group of subjects not on ICS were included. BMD was measured using DEXA (dual energy X-ray absorptiometry) scan. The WHO classification of T-scores for osteopenia and osteoporosis were used. RESULTS:A total of 143 subjects were recruited (69 asthmatics and 74 control subjects). T-scores of the spine, femur, and hip of the asthmatics vs the control subjects were mean, -0.72 vs -0.57 (P=0.98); median, -0.60 vs -0.80 (P=0.474); and mean, 0.19 vs 0.06 (P=0.275); respectively. T-scores of the spine, femur, and hip showed significant negative correlation with age and significant positive correlation with body mass index (BMI). CONCLUSION:The risk factors for osteoporosis and osteopenia among asthmatic patients were older age and lower BMI, but not the cumulative dose of ICS. Asthmatic patients on ICS have no added risk of osteoporosis or osteopenia as compared with non-asthmatic subjects.

journal_name

Ann Thorac Med

authors

Kuan YC,How SH,Azian AA,Liam CK,Ng TH,Fauzi AR

doi

10.4103/1817-1737.94522

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

69-73

issue

2

eissn

1817-1737

issn

1998-3557

pii

ATM-7-69

journal_volume

7

pub_type

杂志文章
  • Ventilator- and interface-related factors influencing patient-ventilator asynchrony during noninvasive ventilation.

    abstract::Patient-ventilator asynchrony (PVA) is common in patients receiving noninvasive ventilation (NIV). This occurs primarily when the triggering and cycling-off of ventilatory assistance are not synchronized with the patient's inspiratory efforts and could result in increased work of breathing and niv failure. In general,...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章,评审

    doi:10.4103/atm.ATM_24_19

    authors: Al Otair HA,BaHammam AS

    更新日期:2020-01-01 00:00:00

  • Pulmonary strongyloidiasis associated CD3+ large granular lymphocytosis.

    abstract::We report a case of pulmonary strongyloidiasis in a patient with large granular lymphocytosis. He was on short-term high dose immunosuppressant therapy. A 77-year-old white male presented to the emergency room with fever and shortness of breath for 10 days. The patient had been diagnosed about 3 months prior to this p...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.78432

    authors: Rishi MA,Chaudhry SZ

    更新日期:2011-04-01 00:00:00

  • Alterations of pulmonary function in patients with inflammatory bowel diseases.

    abstract:AIM:The aim of this study was to investigate the alterations of pulmonary function tests (PFTs) and their relationship with disease activity in inflammatory bowel diseases (IBDs). METHODS:Sixty-four IBD patients (31 Crohn's disease [CD] and 33 ulcerative colitis [UC]) and thirty healthy individuals (controls) were stu...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.191877

    authors: Ji XQ,Ji YB,Wang SX,Zhang CQ,Lu DG

    更新日期:2016-10-01 00:00:00

  • Management of malignant pleural effusion by an indwelling pleural catheter: A cost-efficiency analysis.

    abstract:BACKGROUND:For patients that are expected to survive for longer, the risk of complications combined with the need for more vacuum drainage bottles have become barriers to the placement of indwelling pleural catheter (IPC), since these could increase costs. OBJETIVES:The objective of the current article is to determine...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.160837

    authors: Rial MB,Lamela IP,Fernández VL,Arca JA,Delgado MN,Pombo CV,Hernández CR,Fernández-Villar A

    更新日期:2015-07-01 00:00:00

  • Factors associated with poor asthma control in the outpatient clinic setting.

    abstract:BACKGROUND/OBJECTIVES:The goal of the study was to assess asthma control using asthma control test (ACT) and to explore the factors that effects asthma control among participants with bronchial asthma in the outpatient clinic setting. METHODS:This cross-sectional descriptive study was conducted in the outpatient prima...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.152450

    authors: Al-Zahrani JM,Ahmad A,Al-Harbi A,Khan AM,Al-Bader B,Baharoon S,Shememeri AA,Al-Jahdali H

    更新日期:2015-04-01 00:00:00

  • Erratum: Factors associated with poor asthma control in the outpatient clinic setting: Erratum.

    abstract::[This corrects the article on p. 100 in vol. 10, PMID: 25829960.]. ...

    journal_title:Annals of thoracic medicine

    pub_type: 已发布勘误

    doi:10.4103/1817-1737.160849

    authors:

    更新日期:2015-07-01 00:00:00

  • Whistle in the bronchus.

    abstract::An 18-year-old male presented with 4 weeks' history of productive cough and fever that had started 1 day after alleged ingestion of a plastic whistle. Multiple courses of antibiotics had proved ineffective. Crepitation and a localized wheeze on right chest were observed on clinical examination. Chest radiograph showed...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.33702

    authors: Koul PA,Wahid A,Bhat TA,Hussain T

    更新日期:2007-07-01 00:00:00

  • Progression-free survival, post-progression survival, and tumor response as surrogate markers for overall survival in patients with extensive small cell lung cancer.

    abstract:OBJECTIVES:The effects of first-line chemotherapy on overall survival (OS) might be confounded by subsequent therapies in patients with small cell lung cancer (SCLC). We examined whether progression-free survival (PFS), post-progression survival (PPS), and tumor response could be valid surrogate endpoints for OS after ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.146885

    authors: Imai H,Mori K,Wakuda K,Ono A,Akamatsu H,Shukuya T,Taira T,Kenmotsu H,Naito T,Kaira K,Murakami H,Endo M,Nakajima T,Yamamoto N,Takahashi T

    更新日期:2015-01-01 00:00:00

  • Association between thyroid cancer and epidermal growth factor receptor mutation in female with nonsmall cell lung cancer.

    abstract:BACKGROUND:The aim of this study was to investigate the association between epidermal growth factor receptor (EGFR) mutation and thyroid cancer in female patients with nonsmall-cell lung cancer (NSCLC). METHODS:In a retrospective study, we examined 835 female patients who were diagnosed with NSCLC and underwent an EGF...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.197774

    authors: Kim SY,Kim HR,Kim CH,Koh JS,Baek HJ,Choi CM,Song JS,Lee JC,Na II

    更新日期:2017-01-01 00:00:00

  • Successful pregnancy outcome in Swyer-James-Macleod syndrome.

    abstract::Swyer-James-MacLeod (SJM) syndrome is a chronic, progressive lung disease as a result of infection and bronchial obstruction that ultimately leads to emphysema. It is associated with chronic cough, sputum production and recurrent chest infections and is occasionally seen in women of reproductive age. The radiological ...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.37976

    authors: Chopra S,Aggarwal N,Suri V,Thami MR

    更新日期:2008-01-01 00:00:00

  • Relation of oxidant-antioxidant imbalance with disease progression in patients with asthma.

    abstract:CONTEXT:Asthma is a chronic airway disorder which is associated to the inflammatory cells. Inflammatory and immune cells generate more reactive oxygen species in patients suffering from asthma which leads to tissue injury. AIMS:To investigate the role of oxidant-antioxidant imbalance in disease progression of asthmati...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.102182

    authors: Ahmad A,Shameem M,Husain Q

    更新日期:2012-10-01 00:00:00

  • A near fatal complication following stenting of thoracic aortic aneurysm.

    abstract::Tracheobronchial obstruction along with compression of pulmonary vessels is a rare complication after stenting of aortic aneurysm. We present this rare situation in a young patient who underwent stenting of traumatic thoracic aortic aneurysm and developed this near fatal complication and also the conservative manageme...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.74275

    authors: Hajjar WM,Al Nassar SA,Iftikhar A,Alaqeed AN

    更新日期:2011-01-01 00:00:00

  • Association of bronchoalveolar lavage yield with chest computed tomography findings and symptoms in immunocompromised patients.

    abstract:INTRODUCTION:Fiber-optic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) is a common procedure performed in immunocompromised patients with undiagnosed pulmonary pathology. Identifying patients with the highest potential diagnostic yield may help to avoid morbidity in patients unlikely to benefit from the procedur...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.114302

    authors: Brownback KR,Simpson SQ

    更新日期:2013-07-01 00:00:00

  • Unusual variant of Cantrell's pentalogy?

    abstract::A 12-hour-old male infant presented with prolapsed abdominal content through a defect on left side of chest wall with respiratory distress. A thorough clinical examination suggested absence of ectopia cordis, abdominal wall defect, and any bony anomaly. The child expired after 6 hours of admission because of respirato...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.41916

    authors: Kumar B,Sharma SB,Kandpal DK,Agrawal LD

    更新日期:2008-07-01 00:00:00

  • The influence of intermittent fasting on the circadian pattern of melatonin while controlling for caloric intake, energy expenditure, light exposure, and sleep schedules: A preliminary report.

    abstract:AIMS:We hypothesized that if we control for food composition, caloric intake, light exposure, sleep schedule, and exercise, intermittent fasting would not influence the circadian pattern of melatonin. Therefore, we designed this study to assess the effect of intermittent fasting on the circadian pattern of melatonin. ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/atm.ATM_15_17

    authors: Almeneessier AS,Bahammam AS,Sharif MM,Bahammam SA,Nashwan SZ,Pandi Perumal SR,Cardinali DP,Alzoghaibi M

    更新日期:2017-07-01 00:00:00

  • IL-4 receptor alpha single-nucleotide polymorphisms rs1805010 and rs1801275 are associated with increased risk of asthma in a Saudi Arabian population.

    abstract:BACKGROUND:The IL-4 receptor alpha subunit (IL-4Rα), when associated with the common gamma chain receptor, or the IL-13Rα1 subunit, transduces signals to STAT6 in response to IL-4 and IL-13 stimulations. This results in a number of cell-specific responses including Th2 differentiation, lymphocyte proliferation and IgE ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.128849

    authors: Al-Muhsen S,Vazquez-Tello A,Alzaabi A,Al-Hajjaj MS,Al-Jahdali HH,Halwani R

    更新日期:2014-04-01 00:00:00

  • Anti-interleukin-6 monoclonal antibody for cytokine storm in COVID-19.

    abstract::Novel coronavirus disease 2019 (COVID-19) is known to cause severe pneumonia and acute respiratory distress syndrome which may lead to death. Several treatments have been tested in the race to find a treatment regimen for this deadly viral infection. Tocilizumab, a recombinant humanized anti-interleukin-6 receptor mon...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/atm.ATM_286_20

    authors: Douedi S,Chaudhri M,Miskoff J

    更新日期:2020-07-01 00:00:00

  • Home intravenous antibiotic treatment for acute pulmonary exacerbations in cystic fibrosis - Is it good for the patient?

    abstract::There is a worldwide drive for the home management of chronic respiratory diseases. With the widespread use of home intravenous (IV) treatment for cystic fibrosis (CF) pulmonary exacerbations (PExs), evidence pointing to an inferior outcome of care for home-treated patients in comparison to hospital-treated patients i...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.53346

    authors: Sequeiros IM,Jarad NA

    更新日期:2009-07-01 00:00:00

  • An underestimated cause of chronic cough: The Protracted Bacterial Bronchitis.

    abstract::Chronic cough in childhood is associated with a high morbidity and decreased quality of life. Protracted bacterial bronchitis (PBB) seems to be the second most common cause of chronic cough in children under 6 years of age. Its main clinical feature is represented by wet cough that worsens when changing posture and im...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章,评审

    doi:10.4103/atm.ATM_12_17

    authors: Di Filippo P,Scaparrotta A,Petrosino MI,Attanasi M,Di Pillo S,Chiarelli F,Mohn A

    更新日期:2018-01-01 00:00:00

  • Prevalence of short sleep duration and its association with obesity among adolescents 15- to 19-year olds: A cross-sectional study from three major cities in Saudi Arabia.

    abstract:BACKGROUND:Adequate sleep has been considered important for the adolescent's health and well being. On the other hand, self-imposed sleep curtailment is now recognized as a potentially important and novel risk factor for obesity. The present study aimed to assess the prevalence of short sleep duration and its associati...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.98845

    authors: Al-Hazzaa HM,Musaiger AO,Abahussain NA,Al-Sobayel HI,Qahwaji DM

    更新日期:2012-07-01 00:00:00

  • National Approach to Standardize and Improve Mechanical Ventilation.

    abstract::NASAM (National Approach to Standardize and Improve Mechanical Ventilation) is a national collaborative quality improvement project in Saudi Arabia. It aims to improve the care of mechanically ventilated patients by implementing evidence-based practices with the goal of reducing the rate of ventilator-associated event...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/atm.ATM_63_19

    authors: Arabi YM,Al Aseri Z,Alaama T,Alqahtani A,Alharthy A,Almotairi A,Al Qasim E,Alzahrani AA,Al Qarni M,Abdukahil SAI,Al-Hameed FM,Mandourah Y,Maghrabi K,Ghamdi A,Almekhalfi G,Mady A,Qureshi AS,Qushmaq I,Alshahrani MS,Al

    更新日期:2019-04-01 00:00:00

  • A rare cause of massive hemoptysis in a child: Bronchial Dieulafoy's disease - the first report of transcatheter treatment in pediatric age.

    abstract::We report a case of bronchial Dieulafoy's disease in the pediatric age. Angio-computed tomography scan and arteriography addressed us to diagnosis. Bronchial endoscopy with biopsy was avoided due to the high risk of developing a life-threatening hemorrhage. Transcatheter embolization of the bleeding bronchial artery w...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/atm.ATM_163_20

    authors: Giordano M,Bigazzi MC,Palladino MT,Russo MG

    更新日期:2020-10-01 00:00:00

  • Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Intensive care management of pulmonary hypertension.

    abstract::Pulmonary hypertension (PH) in the Intensive Care Unit (ICU) may be due to preexisting pulmonary vascular lung disease, liver disease, or cardiac diseases. PH also may be caused by critical illnesses, such as acute respiratory distress syndrome (ARDS), acute left ventricular dysfunction and pulmonary embolism, or may ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.134056

    authors: Al-Azem MA,Al-Hazmi MS

    更新日期:2014-07-01 00:00:00

  • Saudi regulations for the accreditation of sleep medicine physicians and technologists.

    abstract::The professional content of sleep medicine has grown significantly over the past few decades, warranting the recognition of sleep medicine as an independent specialty. Because the practice of sleep medicine has expanded in Saudi Arabia over the past few years, a national regulation system to license and ascertain the ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.105710

    authors: Bahammam AS,Al-Jahdali H,Alharbi AS,Alotaibi G,Asiri SM,Alsayegh A

    更新日期:2013-01-01 00:00:00

  • Correlating computed tomography pulmonary angiography signs of right ventricular strain in pulmonary embolisms to clinical outcomes.

    abstract:INTRODUCTION:Right ventricular strain (RVS) in pulmonary embolism (PE) can be used to stratify risk and direct intervention. The clinical significance of computed tomography pulmonary angiogram (CTPA)-derived radiologic signs of RVS, however, remains incompletely characterized. We retrospectively analyzed a cohort of p...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/atm.ATM_264_19

    authors: Karri J,Truong T,Hasapes J,Trujillo DO,Chua S,Shiralkar K,Aisenberg G

    更新日期:2020-04-01 00:00:00

  • Increased ischemia-modified albumin and malondialdehyde levels in videothoracoscopic surgery.

    abstract:BACKGROUND:Videothoracoscopic surgery leads to general organ hypoperfusion by reducing mean arterial pressure, systemic vascular resistance, and end-diastolic volume index. Oxidative stress occurs as a result of hypoperfusion. Evaluation of the short-term effects of videothoracoscopic sympathectomy on serum ischemia-mo...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.172298

    authors: Oncel M,Kiyici A,Oncel M,Sunam GS,Sahin E,Adam B

    更新日期:2016-01-01 00:00:00

  • Performance of QuantiFERON-TB Gold test compared to tuberculin skin test in detecting latent tuberculosis infection in HIV- positive individuals in Iran.

    abstract:BACKGROUND:There is limited data about the performance of QuantiFERON-TB Gold (QFT-G) test in detecting latent tuberculosis infection (LTBI) in our region. We intended to determine the performance of QFT-G compared to conventional tuberculin skin test (TST) in detecting LTBI in HIV-positive individuals in Iran. METHOD...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.58959

    authors: Mardani M,Tabarsi P,Mohammadtaheri Z,Chitsaz E,Farokhzad B,Hadavand F,Gachkar L,Nemati K,Masjedi MR

    更新日期:2010-01-01 00:00:00

  • The Saudi Initiative for Asthma.

    abstract::The Saudi Initiative for Asthma (SINA) provides up-to-date guidelines for healthcare workers managing patients with asthma. SINA was developed by a panel of Saudi experts with respectable academic backgrounds and long-standing experience in the field. SINA is founded on the latest available evidence, local literature,...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.56001

    authors: Al-Moamary MS,Al-Hajjaj MS,Idrees MM,Zeitouni MO,Alanezi MO,Al-Jahdali HH,Al Dabbagh M

    更新日期:2009-10-01 00:00:00

  • Pictorial essay of radiological features of benign intrathoracic masses.

    abstract::With increased exposure of patients to routine imaging, incidental benign intrathoracic masses are frequently recognized. Most have classical imaging features, which are pathognomonic for their benignity. The aim of this pictorial review is to educate the reader of radiological features of several types of intrathorac...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章,评审

    doi:10.4103/1817-1737.160365

    authors: Suut S,Al-Ani Z,Allen C,Rajiah P,Durr-E-Sabih,Al-Harbi A,Al-Jahdali H,Khan AN

    更新日期:2015-10-01 00:00:00

  • Allergic bronchopulmonary aspergillosis: A clinical review of 24 patients: Are we right in frequent serologic monitoring?

    abstract:BACKGROUND:Allergic Broncho Pulmonary Aspergillosis (ABPA) is a rare disease characterized by an allergic inflammatory response to the colonization by aspergillus or other fungi in the airways. The aim was to study the clinical, radiological, and serological characteristics of patients of ABPA. MATERIALS AND METHODS:A...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.140130

    authors: Natarajan S,Subramanian P

    更新日期:2014-10-01 00:00:00