Abstract:
:Patient-ventilator asynchrony (PVA) is common in patients receiving noninvasive ventilation (NIV). This occurs primarily when the triggering and cycling-off of ventilatory assistance are not synchronized with the patient's inspiratory efforts and could result in increased work of breathing and niv failure. In general, five types of asynchrony can occur during NIV: ineffective inspiratory efforts, double-triggering, auto-triggering, short-ventilatory cycling, and long-ventilatory cycling. Many factors that affect PVA are mostly related to the degree of air leakage, level of pressure support, and the type and properties of the interface used. Careful monitoring and adjustment of these factors are essential to reduce PVA and improve patient comfort. In this article, we discuss the machine and interface-related factors that influence PVA during NIV and its effect on the respiratory mechanics during pressure support ventilation, which is the ventilatory mode used most commonly during NIV. For that, we critically evaluated studies that assessed ventilator- and interface-related factors that influence PVA during NIV and proposed therapeutic solutions.
journal_name
Ann Thorac Medjournal_title
Annals of thoracic medicineauthors
Al Otair HA,BaHammam ASdoi
10.4103/atm.ATM_24_19subject
Has Abstractpub_date
2020-01-01 00:00:00pages
1-8issue
1eissn
1817-1737issn
1998-3557pii
ATM-15-1journal_volume
15pub_type
杂志文章,评审abstract::NASAM (National Approach to Standardize and Improve Mechanical Ventilation) is a national collaborative quality improvement project in Saudi Arabia. It aims to improve the care of mechanically ventilated patients by implementing evidence-based practices with the goal of reducing the rate of ventilator-associated event...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_63_19
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Allergic Broncho Pulmonary Aspergillosis (ABPA) is a rare disease characterized by an allergic inflammatory response to the colonization by aspergillus or other fungi in the airways. The aim was to study the clinical, radiological, and serological characteristics of patients of ABPA. MATERIALS AND METHODS:A...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.140130
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Videothoracoscopic surgery leads to general organ hypoperfusion by reducing mean arterial pressure, systemic vascular resistance, and end-diastolic volume index. Oxidative stress occurs as a result of hypoperfusion. Evaluation of the short-term effects of videothoracoscopic sympathectomy on serum ischemia-mo...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.172298
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:There is limited data about the performance of QuantiFERON-TB Gold (QFT-G) test in detecting latent tuberculosis infection (LTBI) in our region. We intended to determine the performance of QFT-G compared to conventional tuberculin skin test (TST) in detecting LTBI in HIV-positive individuals in Iran. METHOD...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.58959
更新日期:2010-01-01 00:00:00
abstract::Pleural effusion is considered to be a rare manifestation of pulmonary sarcoidosis, but hemorrhagic effusion secondary to it is a very uncommon clinical presentation. This case is reported due to the rare manifestation in pulmonary sarcoidosis presenting clinically as hemorrhagic pleural effusion. ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.44783
更新日期:2009-01-01 00:00:00
abstract::Pulmonary tumor thromboembolism is well described in literature especially in patients known to have cancer. We are presenting this report of a patient presenting with Acute Cor-pulmonale secondary to Occult Gastric carcinoma causing pulmonary tumor embolism. This is an unusual presentation of occult neoplasm. ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.36553
更新日期:2007-10-01 00:00:00
abstract::Advances in our understanding of human immunodeficiency virus (HIV) infection have led to improved care and incremental increases in survival. However, the pulmonary manifestations of HIV/acquired immunodeficiency syndrome (AIDS) remain a major cause of morbidity and mortality. Respiratory complaints are not infrequen...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.69106
更新日期:2010-10-01 00:00:00
abstract::Swyer-James-MacLeod (SJM) syndrome is a chronic, progressive lung disease as a result of infection and bronchial obstruction that ultimately leads to emphysema. It is associated with chronic cough, sputum production and recurrent chest infections and is occasionally seen in women of reproductive age. The radiological ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.37976
更新日期:2008-01-01 00:00:00
abstract::Pulmonary hypertension (PH) in the Intensive Care Unit (ICU) may be due to preexisting pulmonary vascular lung disease, liver disease, or cardiac diseases. PH also may be caused by critical illnesses, such as acute respiratory distress syndrome (ARDS), acute left ventricular dysfunction and pulmonary embolism, or may ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.134056
更新日期:2014-07-01 00:00:00
abstract::We report a case of bronchial Dieulafoy's disease in the pediatric age. Angio-computed tomography scan and arteriography addressed us to diagnosis. Bronchial endoscopy with biopsy was avoided due to the high risk of developing a life-threatening hemorrhage. Transcatheter embolization of the bleeding bronchial artery w...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_163_20
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The IL-4 receptor alpha subunit (IL-4Rα), when associated with the common gamma chain receptor, or the IL-13Rα1 subunit, transduces signals to STAT6 in response to IL-4 and IL-13 stimulations. This results in a number of cell-specific responses including Th2 differentiation, lymphocyte proliferation and IgE ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.128849
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Osteoporosis, the most common extra-pulmonary complication of chronic obstructive pulmonary disease (COPD), may be related to general causes or COPD-specific causes such as low forced expiratory volume in 1 s (FEV1) and hypoxia. A few studies reported that emphysema is an independent risk factor for osteopor...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_357_16
更新日期:2017-04-01 00:00:00
abstract:AIMS:The aim of the study was to evaluate the clinical utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with mediastinal and hilar lymphadenopathy and to explicitly describe the utility of this procedure in patient's outcome. METHODS:A retrospective review ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_317_17
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:The effects of first-line chemotherapy on overall survival (OS) might be confounded by subsequent therapies in patients with small cell lung cancer (SCLC). We examined whether progression-free survival (PFS), post-progression survival (PPS), and tumor response could be valid surrogate endpoints for OS after ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.146885
更新日期:2015-01-01 00:00:00
abstract::Novel coronavirus disease 2019 (COVID-19) is known to cause severe pneumonia and acute respiratory distress syndrome which may lead to death. Several treatments have been tested in the race to find a treatment regimen for this deadly viral infection. Tocilizumab, a recombinant humanized anti-interleukin-6 receptor mon...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_286_20
更新日期:2020-07-01 00:00:00
abstract::There is a worldwide drive for the home management of chronic respiratory diseases. With the widespread use of home intravenous (IV) treatment for cystic fibrosis (CF) pulmonary exacerbations (PExs), evidence pointing to an inferior outcome of care for home-treated patients in comparison to hospital-treated patients i...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.53346
更新日期:2009-07-01 00:00:00
abstract:CONTEXT:Asthma is a chronic airway disorder which is associated to the inflammatory cells. Inflammatory and immune cells generate more reactive oxygen species in patients suffering from asthma which leads to tissue injury. AIMS:To investigate the role of oxidant-antioxidant imbalance in disease progression of asthmati...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.102182
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Adequate sleep has been considered important for the adolescent's health and well being. On the other hand, self-imposed sleep curtailment is now recognized as a potentially important and novel risk factor for obesity. The present study aimed to assess the prevalence of short sleep duration and its associati...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.98845
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:For patients that are expected to survive for longer, the risk of complications combined with the need for more vacuum drainage bottles have become barriers to the placement of indwelling pleural catheter (IPC), since these could increase costs. OBJETIVES:The objective of the current article is to determine...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.160837
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:While lung cancer is the leading cancer cause of death, it is largely preventable. Furthermore, early diagnosis enhances the chance of cure. Therefore, we developed guidelines for lung cancer prevention and early detection. METHODS:A multidisciplinary team of experts in lung cancer representing different he...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_147_18
更新日期:2018-10-01 00:00:00
abstract::The reported studies suggest a role for eosinophils in the pathogenesis of cough variant asthma. In the present study, the expired breath condensate level of hydrogen peroxide and pH were determined in patients with cough variant asthma and compared to subjects with classical asthma, with chronic cough nonasthmatic an...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.30357
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Fiber-optic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) is a common procedure performed in immunocompromised patients with undiagnosed pulmonary pathology. Identifying patients with the highest potential diagnostic yield may help to avoid morbidity in patients unlikely to benefit from the procedur...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.114302
更新日期:2013-07-01 00:00:00
abstract::The professional content of sleep medicine has grown significantly over the past few decades, warranting the recognition of sleep medicine as an independent specialty. Because the practice of sleep medicine has expanded in Saudi Arabia over the past few years, a national regulation system to license and ascertain the ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.105710
更新日期:2013-01-01 00:00:00
abstract:AIMS:We hypothesized that if we control for food composition, caloric intake, light exposure, sleep schedule, and exercise, intermittent fasting would not influence the circadian pattern of melatonin. Therefore, we designed this study to assess the effect of intermittent fasting on the circadian pattern of melatonin. ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_15_17
更新日期:2017-07-01 00:00:00
abstract::Tracheobronchial obstruction along with compression of pulmonary vessels is a rare complication after stenting of aortic aneurysm. We present this rare situation in a young patient who underwent stenting of traumatic thoracic aortic aneurysm and developed this near fatal complication and also the conservative manageme...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.74275
更新日期:2011-01-01 00:00:00
abstract:AIM:The aim of this study was to investigate the alterations of pulmonary function tests (PFTs) and their relationship with disease activity in inflammatory bowel diseases (IBDs). METHODS:Sixty-four IBD patients (31 Crohn's disease [CD] and 33 ulcerative colitis [UC]) and thirty healthy individuals (controls) were stu...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.191877
更新日期:2016-10-01 00:00:00
abstract:AIMS:Flexible bronchoscopy is a common procedure performed in pulmonary medicine, critical care, and thoracic surgery. In this study, we aimed to assess the prevalence and predictors of anxiety in patients undergoing diagnostic bronchoscopy. METHODS:This is a prospective study conducted at King Abdulaziz University Ho...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_38_19
更新日期:2019-07-01 00:00:00
abstract::Chronic cough in childhood is associated with a high morbidity and decreased quality of life. Protracted bacterial bronchitis (PBB) seems to be the second most common cause of chronic cough in children under 6 years of age. Its main clinical feature is represented by wet cough that worsens when changing posture and im...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/atm.ATM_12_17
更新日期:2018-01-01 00:00:00
abstract::A 12-hour-old male infant presented with prolapsed abdominal content through a defect on left side of chest wall with respiratory distress. A thorough clinical examination suggested absence of ectopia cordis, abdominal wall defect, and any bony anomaly. The child expired after 6 hours of admission because of respirato...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.41916
更新日期:2008-07-01 00:00:00
abstract::A 21-year-old primigravida, at 32 weeks of gestation, presented with acute onset of respiratory failure and circulatory shock. Chest imaging showed findings suggestive of ruptured hydatid cyst, which was confirmed by histology post-thoracotomy. Tissue cultures from the removed cyst grew Mycobacterium tuberculosis also...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.32234
更新日期:2007-04-01 00:00:00