Association of bronchoalveolar lavage yield with chest computed tomography findings and symptoms in immunocompromised patients.

Abstract:

INTRODUCTION:Fiber-optic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) is a common procedure performed in immunocompromised patients with undiagnosed pulmonary pathology. Identifying patients with the highest potential diagnostic yield may help to avoid morbidity in patients unlikely to benefit from the procedure. We sought to determine which patient factors, specifically chest computed tomography (CT) findings, affected diagnostic yield of BAL. METHODS:Retrospective chart review of immunocompromised patients who underwent FOB with BAL from 01/01/2010 to 12/31/2011 at an academic medical center was performed. The lung lobe lavaged, characteristics of pulmonary infiltrate on radiograph, patient symptoms, and diagnostic yield were collected. A positive diagnostic yield was defined as a positive microbiological culture, finding on cytopathologic staining, diffuse alveolar hemorrhage, alveolar eosinophilia or a positive immunologic or nucleic acid assay. RESULTS:The overall diagnostic yield was 52.6%. Infiltrates that were predominantly reticular or nodular by CT had a lower diagnostic yield than predominantly consolidated, ground-glass, or tree-in-bud infiltrates (36.5% vs. 61.2%, P = 0.0058). The diagnostic yield was significantly improved in patients with both fever and chest symptoms compared to patients without symptoms (61.3% vs. 29.6%, P = 0.0066). CONCLUSION:CT findings of reticular and nodular infiltrates portend a worse diagnostic yield from BAL than those that are alveolar in nature. Symptomatic patients are more likely to have diagnostic FOB with BAL than asymptomatic patients.

journal_name

Ann Thorac Med

authors

Brownback KR,Simpson SQ

doi

10.4103/1817-1737.114302

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

153-9

issue

3

eissn

1817-1737

issn

1998-3557

pii

ATM-8-153

journal_volume

8

pub_type

杂志文章
  • Bronchiolitis obliterans organizing pneumonia: pathogenesis, clinical features, imaging and therapy review.

    abstract::Bronchiolitis obliterans organizing pneumonia (BOOP) was first described in the early 1980s as a clinicopathologic syndrome characterized symptomatically by subacute or chronic respiratory illness and histopathologically by the presence of granulation tissue in the bronchiolar lumen, alveolar ducts and some alveoli, a...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.39641

    authors: Al-Ghanem S,Al-Jahdali H,Bamefleh H,Khan AN

    更新日期:2008-04-01 00:00:00

  • Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Intensive care management of pulmonary hypertension.

    abstract::Pulmonary hypertension (PH) in the Intensive Care Unit (ICU) may be due to preexisting pulmonary vascular lung disease, liver disease, or cardiac diseases. PH also may be caused by critical illnesses, such as acute respiratory distress syndrome (ARDS), acute left ventricular dysfunction and pulmonary embolism, or may ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.134056

    authors: Al-Azem MA,Al-Hazmi MS

    更新日期:2014-07-01 00:00:00

  • Successful pregnancy outcome in Swyer-James-Macleod syndrome.

    abstract::Swyer-James-MacLeod (SJM) syndrome is a chronic, progressive lung disease as a result of infection and bronchial obstruction that ultimately leads to emphysema. It is associated with chronic cough, sputum production and recurrent chest infections and is occasionally seen in women of reproductive age. The radiological ...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.37976

    authors: Chopra S,Aggarwal N,Suri V,Thami MR

    更新日期:2008-01-01 00:00:00

  • Utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration in patients with mediastinal and hilar lymphadenopathy: Western region experience.

    abstract:AIMS:The aim of the study was to evaluate the clinical utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with mediastinal and hilar lymphadenopathy and to explicitly describe the utility of this procedure in patient's outcome. METHODS:A retrospective review ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/atm.ATM_317_17

    authors: Aljohaney AA

    更新日期:2018-04-01 00:00:00

  • Pulmonary tumor thromboembolism: a case report and review of literature.

    abstract::Pulmonary tumor thromboembolism is well described in literature especially in patients known to have cancer. We are presenting this report of a patient presenting with Acute Cor-pulmonale secondary to Occult Gastric carcinoma causing pulmonary tumor embolism. This is an unusual presentation of occult neoplasm. ...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.36553

    authors: Aiyappan V,Alwail A

    更新日期:2007-10-01 00:00:00

  • Level and predictors of anxiety in patients undergoing diagnostic bronchoscopy.

    abstract:AIMS:Flexible bronchoscopy is a common procedure performed in pulmonary medicine, critical care, and thoracic surgery. In this study, we aimed to assess the prevalence and predictors of anxiety in patients undergoing diagnostic bronchoscopy. METHODS:This is a prospective study conducted at King Abdulaziz University Ho...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/atm.ATM_38_19

    authors: Aljohaney AA

    更新日期:2019-07-01 00:00:00

  • Saudi regulations for the accreditation of sleep medicine physicians and technologists.

    abstract::The professional content of sleep medicine has grown significantly over the past few decades, warranting the recognition of sleep medicine as an independent specialty. Because the practice of sleep medicine has expanded in Saudi Arabia over the past few years, a national regulation system to license and ascertain the ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.105710

    authors: Bahammam AS,Al-Jahdali H,Alharbi AS,Alotaibi G,Asiri SM,Alsayegh A

    更新日期:2013-01-01 00:00:00

  • Relation of oxidant-antioxidant imbalance with disease progression in patients with asthma.

    abstract:CONTEXT:Asthma is a chronic airway disorder which is associated to the inflammatory cells. Inflammatory and immune cells generate more reactive oxygen species in patients suffering from asthma which leads to tissue injury. AIMS:To investigate the role of oxidant-antioxidant imbalance in disease progression of asthmati...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.102182

    authors: Ahmad A,Shameem M,Husain Q

    更新日期:2012-10-01 00:00:00

  • Pulmonary hydatid cyst in a pregnant patient causing acute respiratory failure.

    abstract::A 21-year-old primigravida, at 32 weeks of gestation, presented with acute onset of respiratory failure and circulatory shock. Chest imaging showed findings suggestive of ruptured hydatid cyst, which was confirmed by histology post-thoracotomy. Tissue cultures from the removed cyst grew Mycobacterium tuberculosis also...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.32234

    authors: Hijazi MH,Al-Ansari MA

    更新日期:2007-04-01 00:00:00

  • Erratum: Factors associated with poor asthma control in the outpatient clinic setting: Erratum.

    abstract::[This corrects the article on p. 100 in vol. 10, PMID: 25829960.]. ...

    journal_title:Annals of thoracic medicine

    pub_type: 已发布勘误

    doi:10.4103/1817-1737.160849

    authors:

    更新日期:2015-07-01 00:00:00

  • An underestimated cause of chronic cough: The Protracted Bacterial Bronchitis.

    abstract::Chronic cough in childhood is associated with a high morbidity and decreased quality of life. Protracted bacterial bronchitis (PBB) seems to be the second most common cause of chronic cough in children under 6 years of age. Its main clinical feature is represented by wet cough that worsens when changing posture and im...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章,评审

    doi:10.4103/atm.ATM_12_17

    authors: Di Filippo P,Scaparrotta A,Petrosino MI,Attanasi M,Di Pillo S,Chiarelli F,Mohn A

    更新日期:2018-01-01 00:00:00

  • Correlating computed tomography pulmonary angiography signs of right ventricular strain in pulmonary embolisms to clinical outcomes.

    abstract:INTRODUCTION:Right ventricular strain (RVS) in pulmonary embolism (PE) can be used to stratify risk and direct intervention. The clinical significance of computed tomography pulmonary angiogram (CTPA)-derived radiologic signs of RVS, however, remains incompletely characterized. We retrospectively analyzed a cohort of p...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/atm.ATM_264_19

    authors: Karri J,Truong T,Hasapes J,Trujillo DO,Chua S,Shiralkar K,Aisenberg G

    更新日期:2020-04-01 00:00:00

  • Home intravenous antibiotic treatment for acute pulmonary exacerbations in cystic fibrosis - Is it good for the patient?

    abstract::There is a worldwide drive for the home management of chronic respiratory diseases. With the widespread use of home intravenous (IV) treatment for cystic fibrosis (CF) pulmonary exacerbations (PExs), evidence pointing to an inferior outcome of care for home-treated patients in comparison to hospital-treated patients i...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.53346

    authors: Sequeiros IM,Jarad NA

    更新日期:2009-07-01 00:00:00

  • Bone mineral density in asthmatic patients on inhaled corticosteroids in a developing country.

    abstract:INTRODUCTION:Prolonged use of oral corticosteroids is a risk factor for osteoporosis. However, the effect of inhaled corticosteroids (ICS) on bone mineral density (BMD) of asthmatic patients remains controversial. OBJECTIVES:We aimed to determine the prevalence of osteopenia and osteoporosis in our patients with asthm...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.94522

    authors: Kuan YC,How SH,Azian AA,Liam CK,Ng TH,Fauzi AR

    更新日期:2012-04-01 00:00:00

  • Barriers for setting up a pulmonary rehabilitation program in the Eastern Province of Saudi Arabia.

    abstract:BACKGROUND:Pulmonary rehabilitation (PR) programs proven to be one of the most effective treatment options for respiratory diseases; yet, they are not well-established in hospitals in Saudi Arabia. AIM:To determine the main barriers for setting up PR programs in Saudi Arabia. METHODS:A cross-sectional study was condu...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.180028

    authors: Alsubaiei ME,Cafarella PA,Frith PA,McEvoy RD,Effing TW

    更新日期:2016-04-01 00:00:00

  • The Saudi Initiative for Asthma.

    abstract::The Saudi Initiative for Asthma (SINA) provides up-to-date guidelines for healthcare workers managing patients with asthma. SINA was developed by a panel of Saudi experts with respectable academic backgrounds and long-standing experience in the field. SINA is founded on the latest available evidence, local literature,...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.56001

    authors: Al-Moamary MS,Al-Hajjaj MS,Idrees MM,Zeitouni MO,Alanezi MO,Al-Jahdali HH,Al Dabbagh M

    更新日期:2009-10-01 00:00:00

  • Factors associated with poor asthma control in the outpatient clinic setting.

    abstract:BACKGROUND/OBJECTIVES:The goal of the study was to assess asthma control using asthma control test (ACT) and to explore the factors that effects asthma control among participants with bronchial asthma in the outpatient clinic setting. METHODS:This cross-sectional descriptive study was conducted in the outpatient prima...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.152450

    authors: Al-Zahrani JM,Ahmad A,Al-Harbi A,Khan AM,Al-Bader B,Baharoon S,Shememeri AA,Al-Jahdali H

    更新日期:2015-04-01 00:00:00

  • Increased ischemia-modified albumin and malondialdehyde levels in videothoracoscopic surgery.

    abstract:BACKGROUND:Videothoracoscopic surgery leads to general organ hypoperfusion by reducing mean arterial pressure, systemic vascular resistance, and end-diastolic volume index. Oxidative stress occurs as a result of hypoperfusion. Evaluation of the short-term effects of videothoracoscopic sympathectomy on serum ischemia-mo...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.172298

    authors: Oncel M,Kiyici A,Oncel M,Sunam GS,Sahin E,Adam B

    更新日期:2016-01-01 00:00:00

  • A near fatal complication following stenting of thoracic aortic aneurysm.

    abstract::Tracheobronchial obstruction along with compression of pulmonary vessels is a rare complication after stenting of aortic aneurysm. We present this rare situation in a young patient who underwent stenting of traumatic thoracic aortic aneurysm and developed this near fatal complication and also the conservative manageme...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/1817-1737.74275

    authors: Hajjar WM,Al Nassar SA,Iftikhar A,Alaqeed AN

    更新日期:2011-01-01 00:00:00

  • Allergic bronchopulmonary aspergillosis: A clinical review of 24 patients: Are we right in frequent serologic monitoring?

    abstract:BACKGROUND:Allergic Broncho Pulmonary Aspergillosis (ABPA) is a rare disease characterized by an allergic inflammatory response to the colonization by aspergillus or other fungi in the airways. The aim was to study the clinical, radiological, and serological characteristics of patients of ABPA. MATERIALS AND METHODS:A...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.140130

    authors: Natarajan S,Subramanian P

    更新日期:2014-10-01 00:00:00

  • Prognostic factors for bronchoscopic intervention in advanced lung or esophageal cancer patients with malignant airway obstruction.

    abstract:CONTEXT:Bronchoscopic intervention can provide immediate relief from suffocation and an opportunity for additional treatment in patients with malignant airway obstruction. However, few studies have specifically identified prognostic factors affecting the survival of advanced lung or esophageal cancer patients receiving...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.109818

    authors: Song JU,Park HY,Kim H,Jeon K,Um SW,Koh WJ,Suh GY,Chung MP,Kwon OJ

    更新日期:2013-04-01 00:00:00

  • Improving the care of sepsis: Between system redesign and professional responsibility: A roundtable discussion in the world sepsis day, September 25, 2013, Riyadh, Saudi Arabia.

    abstract::This paper summarizes the roundtable discussion in September 25, 2013, Riyadh, Saudi Arabia as part of the World Sepsis Day held in King Abdulaziz Medical City, Riyadh. The objectives of the roundtable discussion were to (1) review the chasm between the current management of sepsis and best practice, (2) discuss syste...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.134066

    authors: Arabi Y,Alamry A,Levy MM,Taher S,Marini AM

    更新日期:2014-07-01 00:00:00

  • Identification and management of cough-induced laryngotracheitis.

    abstract::Chronic cough is associated with repetitive injury to the upper airway and trachea, which can lead to an underdiagnosed pathology known as "cough-induced" laryngotracheitis (CILT). In this report, we describe a case of CILT that responded well to dual therapy. ...

    journal_title:Annals of thoracic medicine

    pub_type:

    doi:10.4103/atm.ATM_21_18

    authors: Rodriguez LE,Rodriguez JE,Boodoosingh DR,Salcedo VM

    更新日期:2018-07-01 00:00:00

  • Association between thyroid cancer and epidermal growth factor receptor mutation in female with nonsmall cell lung cancer.

    abstract:BACKGROUND:The aim of this study was to investigate the association between epidermal growth factor receptor (EGFR) mutation and thyroid cancer in female patients with nonsmall-cell lung cancer (NSCLC). METHODS:In a retrospective study, we examined 835 female patients who were diagnosed with NSCLC and underwent an EGF...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.197774

    authors: Kim SY,Kim HR,Kim CH,Koh JS,Baek HJ,Choi CM,Song JS,Lee JC,Na II

    更新日期:2017-01-01 00:00:00

  • Frontline gefitinib in advanced non-small cell lung cancer: Meta-analysis of published randomized trials.

    abstract:OBJECTIVE:Gefitinib, a small molecule tyrosine kinase inhibitor, showed a substantial effect as a salvage treatment for patients with advanced non-small cell lung cancer (NSCLC) who had failed prior chemotherapy. Subsequent phase III trials in previously untreated patients have failed to demonstrate such benefit. It wa...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.65047

    authors: Ibrahim EM

    更新日期:2010-07-01 00:00:00

  • Pictorial essay of radiological features of benign intrathoracic masses.

    abstract::With increased exposure of patients to routine imaging, incidental benign intrathoracic masses are frequently recognized. Most have classical imaging features, which are pathognomonic for their benignity. The aim of this pictorial review is to educate the reader of radiological features of several types of intrathorac...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章,评审

    doi:10.4103/1817-1737.160365

    authors: Suut S,Al-Ani Z,Allen C,Rajiah P,Durr-E-Sabih,Al-Harbi A,Al-Jahdali H,Khan AN

    更新日期:2015-10-01 00:00:00

  • Imaging lung manifestations of HIV/AIDS.

    abstract::Advances in our understanding of human immunodeficiency virus (HIV) infection have led to improved care and incremental increases in survival. However, the pulmonary manifestations of HIV/acquired immunodeficiency syndrome (AIDS) remain a major cause of morbidity and mortality. Respiratory complaints are not infrequen...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.69106

    authors: Allen CM,Al-Jahdali HH,Irion KL,Al Ghanem S,Gouda A,Khan AN

    更新日期:2010-10-01 00:00:00

  • Building capacity for quality and safety in critical care: A roundtable discussion from the second international patient safety conference in April 9-11, 2013, Riyadh, Saudi Arabia.

    abstract::This paper summarizes the roundtable discussion from the Second International Patient Safety Conference held in April 9-11, 2013, Riyadh, Saudi Arabia. The objectives of the roundtable discussion were to: (1) review the conceptual framework for building capacity in quality and safety in critical care. (2) examine exam...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.118480

    authors: Arabi YM,Taher S,Berenholtz SM,Alamry A,Hijazi R,Alatassi A,Marini AM

    更新日期:2013-10-01 00:00:00

  • Prevalence of short sleep duration and its association with obesity among adolescents 15- to 19-year olds: A cross-sectional study from three major cities in Saudi Arabia.

    abstract:BACKGROUND:Adequate sleep has been considered important for the adolescent's health and well being. On the other hand, self-imposed sleep curtailment is now recognized as a potentially important and novel risk factor for obesity. The present study aimed to assess the prevalence of short sleep duration and its associati...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.98845

    authors: Al-Hazzaa HM,Musaiger AO,Abahussain NA,Al-Sobayel HI,Qahwaji DM

    更新日期:2012-07-01 00:00:00

  • Evaluation of liver transplant candidates: A pulmonary perspective.

    abstract::Chronic liver disease is one of the leading causes of mortality and morbidity in the worldwide adult population. Liver transplant is the gold standard therapy for end-stage liver disease and many patients are on the waiting list for a transplant. A variety of pulmonary disorders are encountered in cirrhotic patients. ...

    journal_title:Annals of thoracic medicine

    pub_type: 杂志文章

    doi:10.4103/1817-1737.82436

    authors: Bozbas SS,Eyuboglu F

    更新日期:2011-07-01 00:00:00