Sodium Intake and Blood Pressure in Patients with Chronic Kidney Disease: A Salty Relationship.

Abstract:

BACKGROUND:Hypertension affects almost all chronic kidney disease patients and is related to poor outcomes. Sodium intake is closely related to blood pressure (BP) levels in this population and decreasing its intake consistently improves the BP control particularly in short-term controlled trials. However, most patients struggle in following a controlled diet on sodium according to the guidelines recommendation due to several factors and barriers discussed in this article. SUMMARY:This review article summarizes the current knowledge related to the associations between sodium consumption, BP, and the risk of cardiovascular disease and chronic kidney disease (CKD); it also provides recommendations of how to achieve sodium intake lowering. Key Messages: Evidences support the benefits in decreasing sodium intake on markers of cardiovascular and renal outcomes in CKD. Trials had shorter follow-up and to maintain long-term sodium intake control is a major challenge. Larger studies with longer follow-up looking at hard endpoints will be important to drive future recommendations.

journal_name

Blood Purif

journal_title

Blood purification

authors

Nerbass FB,Calice-Silva V,Pecoits-Filho R

doi

10.1159/000485154

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

166-172

issue

1-3

eissn

0253-5068

issn

1421-9735

pii

000485154

journal_volume

45

pub_type

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