Abstract:
:The eIF4E-binding protein 1 (4EBP1) has long been known to be completely unstructured without any secondary structures, which contributed significantly to the proposal of the induced fit mechanism for target binding of intrinsically disordered proteins. We show here that 4EBP1 is not completely unstructured, but contains a pre-structured helix.
journal_name
Mol Biosystjournal_title
Molecular bioSystemsauthors
Kim DH,Lee C,Cho YJ,Lee SH,Cha EJ,Lim JE,Sabo TM,Griesinger C,Lee D,Han KHdoi
10.1039/c4mb00532esubject
Has Abstractpub_date
2015-02-01 00:00:00pages
366-9issue
2eissn
1742-206Xissn
1742-2051journal_volume
11pub_type
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