Analysis of T cell receptor repertoire in monozygotic twins concordant and discordant for chronic hepatitis B infection.

abstract：INTRODUCTION:Reconstruction of respiratory epithelium is critical for the fabrication of bioengineered airway implants. Epithelial differentiation is typically achieved using bovine pituitary extract (BPE). Due to the xenogenic nature and undefined composition of BPE, an alternative for human clinical applications, dev...

journal_title：Biochemical and biophysical research communications

authors： Hintze JM,Tchoukalova YD,Sista R,Shah MK,Zhang N,Lott DG

更新日期：2018-09-18 00:00:00

abstract：:The present study was designed to clarify the cellular localization and expression of leptin receptor(s) [OB-R(s)] mRNA including its splice variants and their correlation with the cells which secrete placental hormone, placental lactogen-II (PL-II), in rat placentae. By in situ hybridization analysis, hybridization s...

journal_title：Biochemical and biophysical research communications

authors： Kawai M,Murakami T,Otani S,Shima K,Yamaguchi M,Kishi K

更新日期：1999-04-13 00:00:00

abstract：:Angiotensin II (Ang II), one of the main vasoactive hormones of the renin-angiotensin system, contributes to the development and progression of atherosclerosis by inducing vascular smooth muscle cells (VSMCs) migration. Although previous studies have shown that Ang II upregulates low density lipoprotein receptor-relat...

journal_title：Biochemical and biophysical research communications

authors： Jung HO,Uhm JS,Seo SM,Kim JH,Youn HJ,Baek SH,Chung WS,Seung KB

更新日期：2010-11-26 00:00:00

abstract：:The oxygen reaction of Nitrosomonas europaea cytochrome c oxidase containing either 2Cu or 1Cu per two heme a molecules was investigated by the flow-flash technique at 20 degrees C. The reaction profiles of the bacterial enzyme were essentially the same as those of bovine heart cytochrome c oxidase, although the rate ...

journal_title：Biochemical and biophysical research communications

authors： Orii Y,Sakamoto T,Fukumori Y,Yamanaka T

更新日期：1992-02-14 00:00:00

abstract：:Ferroptosis is a novel form of cell death, which is characterized by accumulation of reactive oxygen species (ROS). Sigma 1 receptor (S1R) has been suggested to function in oxidative stress metabolism. Both erastin and sorafenib significantly induced S1R protein expression. Haloperidol strongly promoted erastin- and s...

journal_title：Biochemical and biophysical research communications

authors： Bai T,Wang S,Zhao Y,Zhu R,Wang W,Sun Y

更新日期：2017-09-30 00:00:00

abstract：:Interleukin (IL)-33 is a novel member of the IL-1 family. IL-33 is primarily synthesized as a 30-kDa precursor (pro-IL-33). Pro-IL-33 is cleaved by caspase-1 into an 18-kDa mature form (mature IL-33) in vitro. Recombinant mature IL-33 has been known to induce T-helper type-2 (Th2)-associated cytokines and inflammatory...

journal_title：Biochemical and biophysical research communications

authors： Hayakawa M,Hayakawa H,Matsuyama Y,Tamemoto H,Okazaki H,Tominaga S

更新日期：2009-09-11 00:00:00

abstract：:Glioma is one of the most common primary brain tumors in adults with a high mortality rate and relapse rate. Thus, finding better effective approaches to treat glioma has become very urgent. Astragaloside IV (AS-IV), the major active triterpenoid in Radix Astragali, has shown anti-tumorigenic properties in certain can...

journal_title：Biochemical and biophysical research communications

authors： Li B,Wang F,Liu N,Shen W,Huang T

更新日期：2017-09-09 00:00:00

abstract：:An exposure of a human myeloma cell line to 2-difluoromethylornithine the mechanism-based inhibitor of ornithine decarboxylase (EC 4.1.1.17), resulted in a selection of tumor cells readily growing in the presence of 4 mM difluoromethylornithine, a concentration that swiftly halted the growth of the parental cells. Det...

journal_title：Biochemical and biophysical research communications

authors： Alhonen-Hongisto L,Leinonen P,Laine R,Jänne J

更新日期：1987-04-14 00:00:00

abstract：:The second open reading frame of avian reovirus S1 gene segment encodes a 17 kDa non-structural protein, named p17. The biological role of p17 is fully unknown so far. Using trypan blue dye exclusion and MTT assay, we demonstrated that the ectopic expression of p17 results in the reduction of viable cell number and ce...

journal_title：Biochemical and biophysical research communications

authors： Liu HJ,Lin PY,Lee JW,Hsu HY,Shih WL

更新日期：2005-10-21 00:00:00

abstract：:The association of endogenous synenkephalin and met-enkephalin containing peptides with the membrane of bovine chromaffin granules and physicochemical characteristics of this association were studied. The associated materials were only released at a non physiological pH range and this effect was enhanced with growing ...

journal_title：Biochemical and biophysical research communications

authors： Ase A,Vindrola O,Aloyz R,Inés M,Vida R,Finkielman S,Nahmod V

更新日期：1989-02-15 00:00:00

abstract：:ATP-binding cassette transporter D2 (D2) is an ABC half transporter that is thought to promote the transport of very long-chain fatty acyl-CoAs into peroxisomes. Both D2 and peroxisomes increase during adipogenesis. Although peroxisomes are essential to both catabolic and anabolic lipid metabolism, their function, and...

journal_title：Biochemical and biophysical research communications

authors： Liu X,Liu J,Lester JD,Pijut SS,Graf GA

更新日期：2015-01-02 00:00:00

abstract：:The relation between platelet-derived growth factor (PDGF)-induced smooth muscle cell migration, measured in Boyden chambers, and cellular arachidonic acid cascade was studied by using rat aortic smooth muscle cells. Partially purified PDGF stimulated cell migration significantly at a concentration of 1.33-133.0 micro...

journal_title：Biochemical and biophysical research communications

authors： Nakao J,Ito H,Chang WC,Koshihara Y,Murota S

更新日期：1983-05-16 00:00:00

abstract：:Lecithin-cholesterol acyltransferase (LCAT) is responsible for the formation of cholesterol esters in plasma and is implicated in the removal of excess cholesterol from peripheral tissues. It is generally accepted that the catalytic mechanism of LCAT is similar to that of serine proteases and lipases involving a Ser, ...

journal_title：Biochemical and biophysical research communications

authors： Adimoolam S,Lee YP,Jonas A

更新日期：1998-02-13 00:00:00

abstract：:Isolated motor endplates from mouse intercostal muscles can be obtained after subcellular fractionation. On these motor endplates, localization of the nicotinic receptor and of the voltage-dependent Na+ channel coincides as demonstrated by double labeling with rhodamine alpha-bungarotoxin and a specific anti-Na+ chann...

journal_title：Biochemical and biophysical research communications

authors： Dreyfus P,Rieger F,Murawsky M,Garcia L,Lombet A,Fosset M,Pauron D,Barhanin J,Lazdunski M

更新日期：1986-08-29 00:00:00

abstract：:We have determined the ability of two well-characterized eukaryotic homing endonucleases, I-PpoI from the myxomycete Physarum polycephalum and I-CreI from the green alga Chlamydomonas reinhardtii, to generate site-specific DNA double-strand breaks in human cells. These 18-kDa proteins cleave highly conserved 15- or 24...

journal_title：Biochemical and biophysical research communications

authors： Monnat RJ Jr,Hackmann AF,Cantrell MA

更新日期：1999-02-05 00:00:00

abstract：:To study its biological functions, tumor necrosis factor precursor (proTNF) with a molecular size of 26-KDa was obtained as a recombinant protein from Escherichia coli. The recombinant proTNF was successfully accumulated in the insoluble form, corresponding to about 10-15% of total E. coli proteins. Solubilization, ge...

journal_title：Biochemical and biophysical research communications

authors： Tanabe Y,Noguchi K,Morikawa A,Mizuno D,Soma G

更新日期：1991-08-30 00:00:00

abstract：AIM:To investigate the effect of endogenous PTH deficiency on osteoclasts during fracture healing and its mechanism. METHODS:A femoral fracture model was used to determine the role of endogenous PTH in fracture healing. Immunohistochemistry, qPCR, and Western blot were used to determine the potential functions and mec...

journal_title：Biochemical and biophysical research communications

authors： Sun P,Wang M,Yin GY

更新日期：2020-05-14 00:00:00

abstract：:Platelet adhesion to VLDL, LDL, HDL, and to a mixture of purified apolipoproteins was examined. Platelets adhered to all the classes of lipoproteins tested. VLDL and the apolipoprotein mixture promoted the greatest degree of adhesion. Platelet adhesion was inhibited by addition of EDTA, RGD-containing peptides and ant...

journal_title：Biochemical and biophysical research communications

authors： Kowalska MA,Tuszynski GP,Capuzzi DM

更新日期：1990-10-15 00:00:00

abstract：:In the rat, pancreatic HCO(-)(3) secretion is believed to be mediated by duct cells with an apical Cl(-)/HCO(-)(3) exchanger acting in parallel with a cAMP-activated Cl(-) channel and protons being extruded through a basolateral Na(+)/H(+) exchanger. However, this may not be the only mechanism for HCO(-)(3) secretion ...

journal_title：Biochemical and biophysical research communications

authors： Thévenod F,Roussa E,Schmitt BM,Romero MF

更新日期：1999-10-14 00:00:00

abstract：:Neural crest cells originating from the posterior rhombencephalon migrate to the cardiac outflow tract and participate in division of the aorta and pulmonary trunk. Ablation of this region of premigratory neural crest in the chick embryos results in nondivision of the outflow vessels. Subtractive hybridization was use...

journal_title：Biochemical and biophysical research communications

authors： Kirby ML,Cheng G,Stadt H,Hunter G

更新日期：1995-07-17 00:00:00

abstract：:Transmissible spongiform encephalopathies are fatal neurodegenerative disorders thought to be transmitted by self-perpetuating conformational conversion of a neuronal membrane glycoprotein (PrP(C), for "cellular prion protein") into an abnormal state (PrP(Sc), for "scrapie prion protein"). Doppel (Dpl) is a protein th...

journal_title：Biochemical and biophysical research communications

authors： Erlich P,Cesbron JY,Lemaire-Vieille C,Curt A,Andrieu JP,Schoehn G,Jamin M,Gagnon J

更新日期：2008-01-18 00:00:00

abstract：:Highly purified bovine heart protein phosphatase 2A catalytic subunit lost virtually all of its activity during storage at -70 degrees. When the enzyme was preincubated with Co2+, over 35% of the original activity was restored. Freshly prepared protein phosphatase 2A purified from bovine heart was stimulated at least ...

journal_title：Biochemical and biophysical research communications

authors： Cai L,Chu Y,Wilson SE,Schlender KK

更新日期：1995-03-08 00:00:00

abstract：:Galanin is a neuroendocrine peptide that modulates many different normal physiological effects including memory, weight, and pain perception. To better understand galanin receptor function, we cloned and characterized the galanin-1 receptor (GALN1R) gene isolated from a human P1 library. We determined that this gene c...

journal_title：Biochemical and biophysical research communications

authors： Lorimer DD,Matkowskj K,Benya RV

更新日期：1997-12-18 00:00:00

abstract：:Rheumatoid arthritis (RA) is characterised by chronic inflammation of synovial tissue with aggressive proliferation of synovial cells causing destruction of cartilage and bone. Immunopathological mechanisms, infectious causes and genetic factors have been discussed, but the etiology of the disease has not been underst...

journal_title：Biochemical and biophysical research communications

authors： Mangasser-Stephan K,Dooley S,Welter C,Mutschler W,Hanselmann RG

更新日期：1997-05-08 00:00:00

abstract：:Runt-related transcription factor-2 (RUNX2) is expressed as two isoforms (type-I and type-II) differing only in their amino terminal sequences. The amino terminus of type-I contains MRIPV instead of MASNSLFSAVTPCQQSFFW in type-II. Although type-II mRNA has been considered osteoblast specific, the RUNX2 protein isoform...

journal_title：Biochemical and biophysical research communications

authors： Sudhakar S,Katz MS,Elango N

更新日期：2001-08-10 00:00:00

abstract：:Recombinant human insulin-like growth factor binding protein 3 (hIGFBP-3) stably expressed in chinese hamster ovary cells (CHO cells) has been purified to homogeneity from serum-free culture media. The purified protein migrates as a doublet (45/43 kDa) upon SDS-PAGE. The purified recombinant hIGFBP-3 is fully active a...

journal_title：Biochemical and biophysical research communications

authors： Tressel TJ,Tatsuno GP,Spratt K,Sommer A

更新日期：1991-07-31 00:00:00

abstract：:Recent research has revealed a role for Ambra1, an autophagy-related gene-related (ATG) protein, in the autophagic pro-survival response, and Ambra1 has been shown to regulate Beclin1 and Beclin1-dependent autophagy in embryonic stem cells and cancer cells. However, whether Ambra1 plays an important role in the autoph...

journal_title：Biochemical and biophysical research communications

authors： Shi C,Wu J,Fu M,Zhang B,Wang J,Yang X,Chi Y

更新日期：2014-09-26 00:00:00

abstract：:A few decades ago, researchers found emerging evidence showing that a number of sequential events lead to the pathological cascade of Alzheimer's disease (AD) which is caused by the accumulation of amyloid beta (Aβ), a physiological peptide, in the brain. Therefore, regulation of Aβ represents a crucial treatment appr...

journal_title：Biochemical and biophysical research communications

authors： Oh JH,Choi S,Shin J,Park JS

更新日期：2016-09-02 00:00:00

abstract：:The age-related reduction in the function of osteoblasts plays a central role in the pathogenesis of bone loss and osteoporosis. Collagen synthesis is a primary function of differentiated osteoblasts, however, the mechanisms for age-related changes in collagen synthesis in human osteoblasts remain elusive. We use Gene...

journal_title：Biochemical and biophysical research communications

authors： Zhang X,Zhao G,Zhang Y,Wang J,Wang Y,Cheng L,Sun M,Rui Y

更新日期：2018-10-12 00:00:00

abstract：:RNA polymerase II carboxyl-terminal domain (pol II CTD) phosphatases that can dephosphorylate both Ser2-PO(4) and Ser5-PO(4) of CTD have been identified in animals and yeasts, however, only Ser5-PO(4)-specific CTD phosphatases have been identified in plants. Among predicted Arabidopsis SCP1-like small phosphatases (SS...

journal_title：Biochemical and biophysical research communications

authors： Feng Y,Kang JS,Kim S,Yun DJ,Lee SY,Bahk JD,Koiwa H

更新日期：2010-06-25 00:00:00