Abstract:
:Continuous-time multistate survival models can be used to describe health-related processes over time. In the presence of interval-censored times for transitions between the living states, the likelihood is constructed using transition probabilities. Models can be specified using parametric or semiparametric shapes for the hazards. Semiparametric hazards can be fitted using P-splines and penalised maximum likelihood estimation. This paper presents a method to estimate flexible multistate models that allow for parametric and semiparametric hazard specifications. The estimation is based on a scoring algorithm. The method is illustrated with data from the English Longitudinal Study of Ageing.
journal_name
Stat Medjournal_title
Statistics in medicineauthors
Machado RJM,van den Hout Adoi
10.1002/sim.7604subject
Has Abstractpub_date
2018-05-10 00:00:00pages
1636-1649issue
10eissn
0277-6715issn
1097-0258journal_volume
37pub_type
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