Abstract:
OBJECTIVE:To evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on mobility among patients with substantial leg impairment after subacute stroke. DESIGN:Double-blinded, stratified, randomized trial involving a sham control group. PARTICIPANTS:Patients who developed unilateral hemiplegia after first-ever subacute stroke and underwent inpatient stroke rehabilitation. METHODS:The 15-day intervention programme used in the present study included the application of rTMS (1 Hz, 15 min) over the leg motor area of the unaffected hemisphere, followed by 45 min physical therapy. Overall, 32 participants were randomly assigned to receive either real rTMS or sham stimulation. Clinical assessments, including the Postural Assessment Scale for Stroke Patients (PASS), balance subscale of the Performance Oriented Mobility Assessment (POMA-b), Fugl-Meyer Assessment, Barthel Index (BI), and Timed Up and Go test, were performed immediately before and after the intervention. RESULTS:Both groups demonstrated significant improvements in all the test results over time. At the post-test assessment, the patients in the real rTMS group demonstrated greater improvements in the PASS, POMA, and BI scores than did the patients in the sham rTMS group. In addition, a significantly higher number of patients in the real rTMS group regained mobility at the post-test assessment compared with the corresponding number of patients in the sham rTMS group. CONCLUSION:Application of 1-Hz rTMS may improve mobility among patients with substantial leg impairment after subacute stroke.
journal_name
J Rehabil Medjournal_title
Journal of rehabilitation medicineauthors
Lin YN,Hu CJ,Chi JY,Lin LF,Yen TH,Lin YK,Liou THdoi
10.2340/16501977-1943subject
Has Abstractpub_date
2015-04-01 00:00:00pages
305-10issue
4eissn
1650-1977issn
1651-2081journal_volume
47pub_type
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journal_title:Journal of rehabilitation medicine
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更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:We tested the hypothesis that physically active people with spinal cord injury do not have increased subclinical atherosclerosis compared with an age-matched able-bodied group. METHODS:Subjects comprised 28 wheelchair athletes with spinal cord injury (mean age 22 (standard deviation (SD) 3) years) and 24 rec...
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更新日期:2015-09-01 00:00:00
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doi:10.2340/16501977-0146
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