Abstract:
:The vast majority of patients who present with pancreatic adenocarcinoma have locally advanced or metastatic disease at the time of presentation without possibility of cure. Although in recent years there have been some new promising chemotherapy regimens that improve overall survival by a few months, the prognosis remains dismal. There is, however, a subset of patients who experience durable stable disease or partial responses after initial courses of chemotherapy with locally advanced disease. In these select patients, there remains interest in local ablative therapy with or without resection as a means for local control, palliation of symptoms, and possible improved survival. This review describes the techniques, complications, and expected benefits of several ablative techniques as a treatment modality for locally advanced pancreatic cancer.
journal_name
Pancreasjournal_title
Pancreasauthors
Shah R,Ostapoff KT,Kuvshinoff B,Hochwald SNdoi
10.1097/MPA.0000000000000948subject
Has Abstractpub_date
2018-01-01 00:00:00pages
6-11issue
1eissn
0885-3177issn
1536-4828pii
00006676-201801000-00002journal_volume
47pub_type
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