Abstract：
:Within-subject, or intra-individual, variability in reaction time (RT) is increasingly recognised as an important indicator of the efficiency of attentional control, yet there have been few investigations of the neural correlates of trial-to-trial RT variability in healthy adults. We sought to determine the neural correlates of intra-individual RT variability during a go/no-go response inhibition task in 27 healthy, male participants. We found that reduced trial-to-trial RT variability (i.e. greater response stability) was significantly associated with greater activation in the left pregenual anterior cingulate. These results support the role of the left anterior cingulate in the dynamic control of attention and efficient response selection. Greater understanding of intra-individual RT variability and top-down attentional control in healthy adults may help to inform disorders that impact executive/attentional control, such as attention deficit hyperactivity disorder and schizophrenia.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Johnson BP,Pinar A,Fornito A,Nandam LS,Hester R,Bellgrove MAdoi
10.1016/j.neuropsychologia.2015.03.015subject
Has Abstractpub_date
2015-06-01 00:00:00pages
22-6eissn
0028-3932issn
1873-3514pii
S0028-3932(15)00120-7journal_volume
72pub_type
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