Abstract:
:This study asks whether lesions in different parts of the brain have different effects on the processing of words typically used to refer to objects with and without action affordances, for example tools and animal-related nouns. A cohort of neurological patients with focal lesions participated in a lexical decision paradigm where nouns semantically related to tools, foods and animals were presented along with matched pseudo-words. Differences in semantic features between the categories were confirmed using extensive semantic ratings whereas all semantic word categories were matched for relevant psycholinguistic variables. In a data-driven region of interest analysis, lesions in dorsal pre- and postcentral grey and white matter areas were associated to specific performance deficits for tool nouns when compared to animal nouns. In contrast, patients with lesions primarily affecting perisylvian inferior-frontal and/or temporal regions presented similar deficits across all semantic word categories tested and likewise a group of age and education matched healthy control participants did not show any category specific differences. These findings falsify brain language models denying the fronto-parietal cortex' role in word recognition and semantic understanding. They are best accounted for by frameworks that acknowledge a role of sensorimotor cortex in the semantic processing of action-related words.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Dreyer FR,Picht T,Frey D,Vajkoczy P,Pulvermüller Fdoi
10.1016/j.neuropsychologia.2020.107384subject
Has Abstractpub_date
2020-04-01 00:00:00pages
107384eissn
0028-3932issn
1873-3514pii
S0028-3932(20)30056-7journal_volume
141pub_type
杂志文章相关文献
NEUROPSYCHOLOGIA文献大全abstract::In this paper the performance of patients with unilateral hemispheric lesions (n = 10 with right brain damage; n = 10 with left brain damage) on a free-field sound localization task was contrasted with that of healthy controls (n = 10). Sound stimuli were presented binaurally in the horizontal plane from eight loudspe...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(95)00167-0
更新日期:1996-09-01 00:00:00
abstract::This study examined the hypothesis that the kinematics of movements performed by PD (Parkinson's disease) patients are differentially affected depending on whether or not the aiming movement has an accuracy constraint. The aiming movements required elbow extension in the horizontal plane on a digitizer. There were two...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(99)00059-7
更新日期:2000-01-01 00:00:00
abstract::Prenatal alcohol exposure causes a variety of cognitive deficits, notably in mathematics and higher order processes such as abstraction. An exploratory battery was developed to examine specific types of number processing impairments in 29 adolescent and adult patients with Fetal Alcohol Syndrome (FAS) and Fetal Alcoho...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(96)00043-7
更新日期:1996-12-01 00:00:00
abstract::To cast light on the possible neural substrate of visual imagery we tested normal participants and one hemianopic patient on simple reaction time (RT) to real and imagined visual stimuli. In one experiment participants were to detect as quickly as possible a luminous square presented at one out of two different retina...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2005.11.012
更新日期:2006-01-01 00:00:00
abstract::Memory impairment was demonstrated in a sample of 46 children and adolescents with brain tumors. The overall distribution of memory scores was skewed positively; over half of the total number of test measures were in the lowest quarter of the score distribution; and more than three-quarters of the individual subjects ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(91)90049-e
更新日期:1991-01-01 00:00:00
abstract::We investigated the role that semantic constraint and participant control over stimulus presentation have on early stages of visual word recognition. Namely, we tested how the presence of a highly constraining sentential context influences the expectations that readers have during incremental sentence processing. Furt...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.107294
更新日期:2020-02-03 00:00:00
abstract::The relationship between age and the latency of the P3 (auditory evoked response potential) component was best described in 55 normals aged 15-89 by separate linear regression equations for those younger and those older than 63. Twelve out of 19 patients with dementia had P3 latencies at FZ and CZ which were delayed b...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(86)90081-3
更新日期:1986-01-01 00:00:00
abstract::Motor imagery is a mental representation of motor behavior which has been widely used to study the cognitive basis of movement. The assumption that real movements and motor imagery (virtual movements) use the same neurobiological basis has been questioned by functional magnetic resonance data. The functional similarit...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2013.02.008
更新日期:2013-05-01 00:00:00
abstract::Faces play an important role in social interaction by conveying information and emotion. Of the various components of the face, color particularly provides important clues with regard to perception of age, sex, health status, and attractiveness. In event-related potential (ERP) studies, the N170 component has been ide...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2012.06.022
更新日期:2012-08-01 00:00:00
abstract::Three experiments are reported that use a number of lateralized tasks believed to draw on processes localized to the temporal, occipital or frontal lobes. Oblique factor analyses of the resultant asymmetries indicate the existence of nine lateralized functions, characterized as auditory lexical, facial figural, facial...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(92)90049-r
更新日期:1992-11-01 00:00:00
abstract::The phonological deficit hypothesis of dyslexia has been investigated in the present research by analysing language-related lateralization of the EEG theta band in a sample of dyslexic children. To this aim, a paradigm based on word-pair visual presentation was used in which the same words were processed in Semantic a...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.06.009
更新日期:2006-01-01 00:00:00
abstract::Understanding memory mechanisms is crucial in the study of infant social and cognitive development. Here, we show that the Nc ERP component, known to reflect frequency-related attentional and/or memory processes, is a good candidate to investigate infant recognition memory. Previous paradigms have only investigated th...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2017.08.023
更新日期:2019-03-18 00:00:00
abstract::The relationship between lateral eye movement directionality and type of cognitive task was investigated in a single blind subject with septo-optic dysplasia. Results from an 80-item test showed that rightward eye movements were significantly associated with verbal tasks and leftward eye movements with spatial tasks. ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(85)90109-5
更新日期:1985-01-01 00:00:00
abstract::It is known that the left hemisphere of the human brain is critical in understanding and producing spoken language, but it remains a topic of great interest determining the cerebral lateralization of multiple languages. The aim of this study is to examine the effects of similarity between languages on hemispheric asym...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2013.03.016
更新日期:2013-06-01 00:00:00
abstract::The neural substrates of auditory motion processing are, at present, still a matter of debate. It has been hypothesized that motion information is, as in the visual system, processed separately from other aspects of auditory information, such as stationary location. Here we aimed to differentiate the location of audit...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.11.038
更新日期:2011-01-01 00:00:00
abstract::Visuomotor adaptation to a shift in visual input produced by prismatic lenses is an example of dynamic sensory-motor plasticity within the brain. Prism adaptation is readily induced in healthy individuals, and is thought to reflect the brain's ability to compensate for drifts in spatial calibration between different s...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.05.006
更新日期:2010-07-01 00:00:00
abstract::Event-related potentials (ERPs) were recorded during a task which required subjects to discriminate between rhyming and non-rhyming visually presented pairs of letter strings, consisting of equal proportions of word-word and word-non-word combinations. Pair members were presented sequentially with an interstimulus int...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(84)90038-1
更新日期:1984-01-01 00:00:00
abstract::Benton's test of Stereognosis was administered separately to the left and right hands of six patients with complete cerebral commissurotomy and two patients with partial commissurotomy sparing the splenium. Experiment 1 displayed the multiple choice card in free vision for all patients whereas Experiment 2 displayed i...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(98)00057-8
更新日期:1998-10-01 00:00:00
abstract::Recent studies have suggested an uneven profile of executive dysfunction in autism spectrum disorders (ASD). For example, some authors have reported deficits on newly developed tests of executive function sensitive to rostral prefrontal function, despite spared, or even superior, performance on other tests. We investi...
journal_title:Neuropsychologia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.neuropsychologia.2008.03.025
更新日期:2008-01-01 00:00:00
abstract::Using repetitive transcranical magnetic stimulation (rTMS), we investigated the functional relevance of posterior parietal cortex for categorical and coordinate judgements in the spatial imagery domain. In the coordinate task, subjects were asked to imagine two analogue clock faces based on acoustically presented pair...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.01.017
更新日期:2006-01-01 00:00:00
abstract::Judgments about personalities and social traits can be made by relatively brief exposure to animate living things. Here we show that unusual architecture in the microstructure of the human brain is related to atypical mental projections of personality and social structure onto things that are neither living nor animat...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2016.08.020
更新日期:2016-10-01 00:00:00
abstract::White matter microstructure changes substantially in aging. To better understand how the integrity of white matter structures supports the selective learning of rewarding material, 23 healthy older adults were tested on a value-directed remembering task. This task involved successive free recall word lists where items...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.04.003
更新日期:2019-06-01 00:00:00
abstract::The repetitive finger tapping of 24 right-handed subjects from dextral and sinistral families was evaluated. Subjects tapped with and without concurrent verbal tasks which included reciting a nursery rhyme, reading words (silent vs aloud) and solving anagrams (silent vs aloud). Overall, results indicated that the conc...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(83)90059-3
更新日期:1983-01-01 00:00:00
abstract::It has been proposed that patients with spatial neglect fail to respond appropriately toward stimuli opposite their brain lesion because they have an impairment of directing attention. However, a disorder of 'intention' - or movement initiation - has also been demonstrated in this condition. Recently, the paths of neg...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(99)00083-4
更新日期:2000-01-01 00:00:00
abstract::In Experiment I normal subjects performed the classical clinical line-bisection task, and demonstrated a left-side underestimation. In Experiment II subjects maintained fixation upon a central position and adjusted a rod passing through this fixation point so that both extremities were judged equal. The left-side unde...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(85)90029-6
更新日期:1985-01-01 00:00:00
abstract::Parkinson's disease (PD) is a neurodegenerative disorder affecting voluntary motor control. However, little is known about the experience of voluntary action in PD patients. A key component of action experience is the feeling of controlling one's own actions, and through them, external events. In healthy individuals t...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2009.12.014
更新日期:2010-03-01 00:00:00
abstract::In everyday life, we constantly need to remember the temporal sequence of visual events over short periods of time, for example, when making sense of others' actions or watching a movie. While there is increasing knowledge available on neural mechanisms underlying visual working memory (VWM) regarding the identity and...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.03.012
更新日期:2019-06-01 00:00:00
abstract::The accuracy, reaction and movement time of pointing movements to visual targets were examined in children aged 3-13 yr with infantile hemiplegia and compared to those of comparably aged normal children. Hemiplegic children pointed with the "good" hand (i.e. ipsilateral to the lesion). Half the normal children used th...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(89)90019-5
更新日期:1989-01-01 00:00:00
abstract::To test the idea that associated with stuttering is a cognitive difficulty related to the organization of sequences of responses, stutterers and fluent speakers were compared on a task that required the transcription to paper of rapidly presented letter sequences ranging in length from 3 to 10 letters. Compared to flu...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(87)90123-0
更新日期:1987-01-01 00:00:00
abstract::While skilled readers produce an increased and left-lateralized event-related-potential (ERP) component, known as N170, for strings of letters compared to strings of less familiar units, it remains unclear whether perceptual familiarity plays an important role in driving the increased and left-lateralized N170 for pri...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.107194
更新日期:2019-11-01 00:00:00