Correction to: Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study.

abstract：:Meningiomas, one of the most common benign brain tumors in humans, arise from arachnoid cells in the brain meninges. Our investigations have revealed that miR-335 is a typical microRNA overexpressed in meningiomas in humans. Characterization of the effects of miR-335 overexpression in meningiomas demonstrated that ele...

journal_title：Journal of neuro-oncology

authors： Shi L,Jiang D,Sun G,Wan Y,Zhang S,Zeng Y,Pan T,Wang Z

更新日期：2012-11-01 00:00:00

abstract：:An anti-epithelial membrane antigen monoclonal (Clone E29) was used as part of a panel of antisera in the investigation of primary CNS and metastatic tumours. In contrast to others, definite and often strongly positive cross-reactivity has been demonstrated on glial cells. The material consisted of fourteen astrocytom...

journal_title：Journal of neuro-oncology

authors： Hitchcock E,Morris CS

更新日期：1987-01-01 00:00:00

abstract：:NeuroCogFX is a short yet comprehensive computer-based neuropsychological battery of tests developed to investigate neurological patients for cognitive dysfunction after potentially neurotoxic therapy. NeuroCogFX had been standardized in a group of 242 healthy controls (Fliessbach et al., Fortschr Neurol Psychiatr 74:...

journal_title：Journal of neuro-oncology

authors： Fliessbach K,Rogowski S,Hoppe C,Sabel M,Goeppert M,Helmstaedter C,Calabrese P,Schackert G,Tonn JC,Simon M,Schlegel U

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:To improve the standard treatment paradigm for glioblastoma (GBM), efforts have been made to explore the efficacy of epigenetic agents as chemosensitizers. Recent data suggest possible synergy between decitabine (DAC), a DNA hypomethylating agent, and temozolomide (TMZ) in GBM, but the mechanism remains un...

journal_title：Journal of neuro-oncology

authors： Gallitto M,Cheng He R,Inocencio JF,Wang H,Zhang Y,Deikus G,Wasserman I,Strahl M,Smith M,Sebra R,Yong RL

更新日期：2020-05-01 00:00:00

abstract：:Recently, many studies have found that the miR-106b ~25 cluster plays an oncogenic role in tumor progression. However, the precise role of each microRNAs (miRNAs) in the cluster is not yet clear. In the present study, we examined the expression of miR-106b in glioma samples and a tissue microarray by real-time PCR and...

journal_title：Journal of neuro-oncology

authors： Zhang A,Hao J,Wang K,Huang Q,Yu K,Kang C,Wang G,Jia Z,Han L,Pu P

更新日期：2013-04-01 00:00:00

abstract：:Despite the accumulating evidences of high chemosensitivity especially in anaplastic oligodendrogliomas with loss of chromosomes 1p and 19q, the optimal management strategy for low-grade tumors using the 1p/19q information remains controversial. We have treated all low-grade oligodendrogliomas by a chemotherapy-preced...

journal_title：Journal of neuro-oncology

authors： Iwadate Y,Matsutani T,Hasegawa Y,Shinozaki N,Higuchi Y,Saeki N

更新日期：2011-05-01 00:00:00

abstract：:Ependymomas (EPN) show site specific genetic alterations and a recent DNA methylation profiling study identified nine molecular subgroups. C11orf95-RELA and YAP1 fusions characterise the RELA and YAP1 molecular subgroups, respectively, of supratentorial (ST)-EPNs. Current guidelines recommend molecular subgrouping ove...

journal_title：Journal of neuro-oncology

authors： Malgulwar PB,Nambirajan A,Pathak P,Faruq M,Rajeshwari M,Singh M,Suri V,Sarkar C,Sharma MC

更新日期：2018-05-01 00:00:00

abstract：:Extra-axial cerebellopontine angle (CPA) tumors account for approximately 10% of all brain neoplasms in adults. Vestibular schwannomas are the most common, followed by meningiomas. Gliomas in the CPA are rare and quite often are the exophytic extension of primary brain stem or cerebellar tumors. We describe a pilocyti...

journal_title：Journal of neuro-oncology

authors： Francesco F,Maurizio I,Stefano C,Marina S,Ugo S,Massimo S

更新日期：2010-04-01 00:00:00

abstract：:Anti-VEGF therapy with Bevacizumab (BEV) is widely used in cases of relapsed high-grade glioma (HGG). Arterial hypertension is a known side effect of anti-VEGF therapy. 42 Patients with relapsed HGG were treated with BEV 10 mg/kg on days 1 and 15 of 28-day cycles in addition to treatment with 40 mg TMZ daily until dis...

journal_title：Journal of neuro-oncology

authors： Bumes E,Rzonsa S,Hutterer M,Proescholdt M,Bogdahn U,Riemenschneider MJ,Uhl M,Wendl C,Hau P

更新日期：2016-03-01 00:00:00

abstract：:In a retrospective analysis based on a malignant glioma databank, we describe effects of age, sex and diagnosis upon survival in patients with malignant cerebral glioma with a pre-treatment Karnofsky-index of 60 or more. All patients had been treated with 55-60Gy radiotherapy and nitrosurea-based adjuvant chemotherapy...

journal_title：Journal of neuro-oncology

authors： Diete S,Treuheit T,Dietzmann K,Schmidt U,Wallesch CW

更新日期：2001-05-01 00:00:00

abstract：:Identification of patients suffering from elevated psychosocial distress, the sources of the distress, and the necessary treatment of the distress can be rather difficult within the neurosurgical setting (e.g., lack of time, cognitive or aphasic disorders of the patients). The distress thermometer (DT) is a single-ite...

journal_title：Journal of neuro-oncology

authors： Goebel S,Mehdorn HM

更新日期：2011-08-01 00:00:00

abstract：:Brain metastasis often has a poor prognosis in patients with advanced non-small cell lung cancer (NSCLC). Therefore, it is urgent to identify factors associated with lung cancer brain metastasis. Metastasis associated lung adenocarcinoma transcript 1 (MALAT1) also known as noncoding nuclear-enriched abundant transcrip...

journal_title：Journal of neuro-oncology

authors： Shen L,Chen L,Wang Y,Jiang X,Xia H,Zhuang Z

更新日期：2015-01-01 00:00:00

abstract：:We report a case of a 2 year-old boy who initially presented with macrocephaly and severe global developmental delay. Imaging revealed a large left temporo-parietal mass that was lobulated, calcified, focally enhancing and partially cystic. A second surgery was required for tumor recurrence approximately one year late...

journal_title：Journal of neuro-oncology

authors： Dunham C,Sugo E,Tobias V,Wills E,Perry A

更新日期：2007-08-01 00:00:00

abstract：:To evaluate whether vigorous treatment is beneficial for patients with meningeal gliomatosis (MG) we reviewed the case records of 20 consecutive patients treated for a symptomatic MG in our center. All received systemic or intrathecal chemotherapy and six received additional cranial or spinal radiotherapy. Six patient...

journal_title：Journal of neuro-oncology

authors： Pradat PF,Hoang-Xuan K,Cornu P,Mokhtari K,Martin-Duverneuil N,Poisson M,Delattre JY

更新日期：1999-09-01 00:00:00

abstract：PURPOSE:This study was undertaken to evaluate the radiographic response to two cycles of chemotherapy prior to irradiation in newly diagnosed children with high-grade astrocytomas. PATIENTS AND METHODS:One hundred and thirty children less than 21 years of age with newly-diagnosed high-grade astrocytoma were treated wi...

journal_title：Journal of neuro-oncology

authors： Finlay JL,Geyer JR,Turski PA,Yates AJ,Boyett JM,Allen JC,Packer RJ

更新日期：1994-01-01 00:00:00

abstract：:Recurrent and progressive non-GBM gliomas are a diverse group of brain tumors that often respond poorly to adjuvant chemotherapy treatment. Regional intra-arterial (IA) administration of chemotherapy may result in increased tumor uptake of drug, with improvement in response rates and time to progression (TTP). Twenty-...

journal_title：Journal of neuro-oncology

authors： Newton HB,Slivka MA,Stevens CL,Bourekas EC,Christoforidis GA,Baujan MA,Chakeres DW

更新日期：2002-01-01 00:00:00

abstract：:Leiomyosarcoma has recently been identified as an AIDS-related tumor, usually occurring in children in the chest or abdomen. We describe a case of intracranial leiomyosarcoma in an adult with AIDS. An enhancing mass adjacent to the right occipital cortical surface was diagnosed during a work-up for left arm weakness. ...

journal_title：Journal of neuro-oncology

authors： Litofsky NS,Pihan G,Corvi F,Smith TW

更新日期：1998-11-01 00:00:00

abstract：:Glioma is the most common primary brain tumor in adults. Six3 is a human homologue of the highly conserved sine oculis gene family and essential transcription regulatory factor in process of eye and fetal forebrain development. However, little is known about the role of Six3 in human tumorigenesis. The aim of this stu...

journal_title：Journal of neuro-oncology

authors： Zhang B,Shen C,Ge F,Ma T,Zhang Z

更新日期：2017-07-01 00:00:00

abstract：:High-dose (1-3.5 g/m2) methotrexate (MTX) followed by whole-brain radiation therapy (WBRT) has consistently improved length of survival in primary central nervous system lymphoma (PCNSL), but the prognosis remains dismal. To optimize and enhance the dose intensity of MTX, we applied MTX at 8 g/m2 to 20 patients with P...

journal_title：Journal of neuro-oncology

authors： Watanabe T,Katayama Y,Yoshino A,Komine C,Yokoyama T,Fukushima T

更新日期：2003-05-01 00:00:00

abstract：:Nuclear factor (NF)-kappaB is known to control cellular proliferation and apoptosis. In malignant astrocytoma cells, it was reported that NF-kappaB was activated aberrantly and promoted their proliferation. Thus, inhibition of NF-kappaB activity is considered to be a promising therapeutic strategy for malignant astroc...

journal_title：Journal of neuro-oncology

authors： Nagai S,Kurimoto M,Washiyama K,Hirashima Y,Kumanishi T,Endo S

更新日期：2005-09-01 00:00:00

abstract：:Both cell proliferation and cell death occur simultaneously in tumor tissue, and extent of tumor growth reflects the net balance of these events. We correlated cell proliferation, spontaneous cell death, and alterations in tumor suppressor proteins with one another and with survival of patients with primary astrocytic...

journal_title：Journal of neuro-oncology

authors： Nakamizo A,Inamura T,Ikezaki K,Yoshimoto K,Inoha S,Mizoguchi M,Amano T,Fukui M

更新日期：2002-04-01 00:00:00

abstract：:Extracranial metastases from glioblastoma (GBM) are uncommon with an estimated incidence of less than 2%. We report two cases of metastatic GBM seen within an 8-week period followed by a literature review. We attempted to identify common factors or a causative mechanism. Factors that predominated among the reviewed ca...

journal_title：Journal of neuro-oncology

authors： Kalokhe G,Grimm SA,Chandler JP,Helenowski I,Rademaker A,Raizer JJ

更新日期：2012-03-01 00:00:00

abstract：:The toxicity of IL-2 and/or C. Parvum when injected directly into the mouse brain was examined by survival and histopathology using different numbers of injections, different doses of IL-2, different solvents for the IL-2, and different doses and routes of administration of C. Parvum. Two injections was found signific...

journal_title：Journal of neuro-oncology

authors： Sutton RC 3rd,Kennedy J,Duncan J,Conley FK

更新日期：1989-09-01 00:00:00

abstract：:The effect of methionine enkephalin on the growth of human brain tumor cells was investigated. The results show that this endogenous opioid has dual effects on tumor cell growth. This peptide exerted an inhibitory effect in SK-N-MC human neuroblastoma cell line; in contrast, in U-373 MG human astrocytoma cell line, th...

journal_title：Journal of neuro-oncology

authors： Lee YS,Wurster RD

更新日期：1994-01-01 00:00:00

abstract：:Invasion of the meninges is a relatively common complication of head and neck rhabdomyosarcoma (RMS), while RMS arising primarily within the brain or meninges is rare. We report the case of an 11-year old child with a primary "primitive" frontal lobe tumor, subsequent leptomeningeal spread and fatal intratumoral hemor...

journal_title：Journal of neuro-oncology

authors： Dropcho EJ,Allen JC

更新日期：1987-01-01 00:00:00

abstract：:The outcome of children less than 3 years of age with medulloblastoma has been poor in comparison to older children. The cure rates were below 30%, and the quality of life for cured children was frequently reduced by a complex syndrome of long-term sequelae including intellectual retardation and growth hormone deficie...

journal_title：Journal of neuro-oncology

authors： Schmandt S,Kühl J

更新日期：1998-06-01 00:00:00

abstract：:A positron emission tomography study using [18F]-fluorodeoxyglucose was undertaken to identify and quantitate whether diaschisis occurred in cerebral cortex, basal ganglia, or thalamus, as well as in cerebellar cortex and dentate nuclei in patients with malignant glioma. The relationship between diaschisis in these ce...

journal_title：Journal of neuro-oncology

authors： Rozental JM,Levine RL,Nickles RJ,Dobkin JA,Hanson JM

更新日期：1990-04-01 00:00:00

abstract：:The type III mutant epidermal growth factor receptor (EGFR) is expressed on the cell surface of a subset of glioma, but not of normal tissues. In this study, we investigated the in vivo kinetics of 3C10 mouse monoclonal antibody (mAb), specifically recognizing the type III mutant EGFR (EGFRvIII), using athymic nude mi...

journal_title：Journal of neuro-oncology

authors： Takasu S,Takahashi T,Okamoto S,Oriuchi N,Nakayashiki N,Okamoto K,Muramatsu H,Hayashi T,Nakahara N,Mizuno M,Wakabayashi T,Higuchi T,Endo K,Kozaki K,Miyaishi O,Saga S,Ueda R,Yoshida J,Yoshikawa K

更新日期：2003-07-01 00:00:00

abstract：:Cavernous sinus is an uncommon site of metastasis for the head and neck tumors, and especially for the tumors of parotid gland. The case reported here is the second reported case of parotid carcinoma metastatic to the cavernous sinus, proven by histopathology. Also it is the first reported parotid gland acinic cell ca...

journal_title：Journal of neuro-oncology

authors： Yildirim N,Oksüzoğlu B,Vural M,Han O,Zengin N

更新日期：2005-06-01 00:00:00

abstract：:The optimal treatment of recurrent glioblastoma (GBM) in elderly patients is unclear. Fotemustine (FTM) is a third-generation nitrosourea showing efficacy in gliomas and it has been used with different schedules in adult patients. We performed, for the first time anywhere, a mono-institutional retrospective study to a...

journal_title：Journal of neuro-oncology

authors： Lombardi G,Bellu L,Pambuku A,Della Puppa A,Fiduccia P,Farina M,D'Avella D,Zagonel V

更新日期：2016-07-01 00:00:00