Developing Cancer Informatics Applications and Tools Using the NCI Genomic Data Commons API.

Abstract:

:The NCI Genomic Data Commons (GDC) was launched in 2016 and makes available over 4 petabytes (PB) of cancer genomic and associated clinical data to the research community. This dataset continues to grow and currently includes over 14,500 patients. The GDC is an example of a biomedical data commons, which collocates biomedical data with storage and computing infrastructure and commonly used web services, software applications, and tools to create a secure, interoperable, and extensible resource for researchers. The GDC is (i) a data repository for downloading data that have been submitted to it, and also a system that (ii) applies a common set of bioinformatics pipelines to submitted data; (iii) reanalyzes existing data when new pipelines are developed; and (iv) allows users to build their own applications and systems that interoperate with the GDC using the GDC Application Programming Interface (API). We describe the GDC API and how it has been used both by the GDC itself and by third parties. Cancer Res; 77(21); e15-18. ©2017 AACR.

journal_name

Cancer Res

journal_title

Cancer research

authors

Wilson S,Fitzsimons M,Ferguson M,Heath A,Jensen M,Miller J,Murphy MW,Porter J,Sahni H,Staudt L,Tang Y,Wang Z,Yu C,Zhang J,Ferretti V,Grossman RL,GDC Project.

doi

10.1158/0008-5472.CAN-17-0598

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

e15-e18

issue

21

eissn

0008-5472

issn

1538-7445

pii

77/21/e15

journal_volume

77

pub_type

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