Abstract:
:Fertilized hen eggs were topically applied with 2,4-Dichlorophenoxyacetic acid butyl ester (3.1 mg/egg) before starting incubation. During the incubation time 20% of the compound applied on eggs was lost by volatilization. At different incubation times (0, 1, 5, 10 and 15 days) the wash-off technique was applied to fertile hen eggs and residue analyses of 2,4-D ester were determined and quantified by gas chromatography with an electron capture detector. We found that 2,4-D ester began to be detectable at the embryo from the 5th incubation day and the amount of the compound progressively increased during chick embryonic development. Furthermore chicks hatched from treated eggs showed the presence of the compound in all studied tissues and the highest levels were found in organs such as brain and kidney.
journal_name
Drug Chem Toxicoljournal_title
Drug and chemical toxicologyauthors
Castro de Cantarini SM,Evangelista de Duffard AM,Duffard ROdoi
10.3109/01480548908999150subject
Has Abstractpub_date
1989-06-01 00:00:00pages
137-46issue
2eissn
0148-0545issn
1525-6014journal_volume
12pub_type
杂志文章abstract::In this study, the hepatoprotective activity of methanol bark extract of Alangium salviifolium (BEA) was evaluated for biochemical and histological parameters in swiss albino mice with CCl4-induced hepatotoxicity. The hepatomodulatory effect of two doses of BEA (20 and 50 mg/kg bw for 15 days by oral gavage) was asses...
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