Abstract:
:The effect of some cellular function inhibitors on adsorption and successive events of penetration of vesicular stomatitis virus to phylogenetically unrelated permissive cells was investigated. Treatment of HeLa, CER, EPC and Aedes albopictus cells with colcemide and cytochalasin D which affect cytoskeleton organization indicated that microfilaments but not microtubules were involved in the early events of VSV infection. Inhibitors of oxidative phosphorylation such as dinitrophenol and sodium azide, and the glycolysis inhibitor 2-deoxy-D-glucose, did not allow multiplication of prebound virions, demonstrating that VSV replication is largely energy dependent in either host cells examined.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Superti F,Seganti L,Orsi Nsubject
Has Abstractpub_date
1988-11-01 00:00:00pages
487-93issue
6eissn
0001-723Xissn
1336-2305journal_volume
32pub_type
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