Central antihypertensive effects of chronic treatment with RB150: an orally active aminopeptidase A inhibitor in deoxycorticosterone acetate-salt rats.

abstract：OBJECTIVE:To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS:The study included 80 sedentary, overweight patients (43 female and 37 male) with unmedicated high normal bloo...

journal_title：Journal of hypertension

authors： Pierson LM,Bacon SL,Sherwood A,Hinderliter AL,Babyak M,Gullette EC,Waugh R,Blumenthal JA

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To determine whether the decision to treat uncomplicated mild hypertension with drugs, in accordance with the World Health Organization - International Society of Hypertension (WHO/ISH) guidelines based on a series of blood pressure (BP) measurements over 6 months, resulted in the treatment of patients at hig...

journal_title：Journal of hypertension

authors： Abergel E,Chatellier G,Battaglia C,Menard J

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To describe several emerging concepts regarding the biosynthesis, metabolism and biological roles of adenosine and to illustrate the possible significance of these ideas to vascular biology by proposing a hypothesis pertaining to the role of erythrocyte-derived adenosine deaminase in vaso-occlusive diseases a...

journal_title：Journal of hypertension

authors： Jackson EK,Koehler M,Mi Z,Dubey RK,Tofovic SP,Carcillo JA,Jones GS

更新日期：1996-01-01 00:00:00

abstract：:Two formulations of felodipine, conventional and extended release (ER) tablets, were compared in a double-blind, crossover study of patients whose blood pressure was not being controlled using metoprolol 100 mg once daily. Nineteen patients with a supine diastolic blood pressure greater than or equal to 95 mmHg after ...

journal_title：Journal of hypertension

authors： McGrath BP,Langton D,Matthews PG,Syme S,Treloar K,McNeil JJ

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:In arteries, agonists such as acetylcholine release an endothelium-derived hyperpolarizing factor (EDHF) that is neither nitric oxide nor prostacyclin. OBJECTIVES:To examine the responses to acetylcholine in segments of forearm veins from patients with chronic renal failure who either had never received dia...

journal_title：Journal of hypertension

authors： Martinez-León JB,Segarra G,Medina P,Vila JM,Lluch P,Peiró M,Otero E,Lluch S

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of hypertension and the rate of decline in renal function in a sample of 47 Olivetti Heart Study (OHS) participants whose blood pressure (BP) salt-sensitivity and renal tubular sodium handling had been assessed in 1987-88. METHODS:During the 2002-04 OHS follow-up examination, medica...

journal_title：Journal of hypertension

authors： Barba G,Galletti F,Cappuccio FP,Siani A,Venezia A,Versiero M,Della Valle E,Sorrentino P,Tarantino G,Farinaro E,Strazzullo P

更新日期：2007-07-01 00:00:00

abstract：:Blood pressure was measured in 864 young people aged 16-24 years, 8 years after both of their parents had their blood pressures measured as part of the screening phase of the Medical Research Council Mild Hypertension Trial. Only 29% of offspring with a conventional 'family history of hypertension', defined in terms o...

journal_title：Journal of hypertension

authors： Watt GC,Foy CJ,Holton DW,Edwards HE

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of hypertension and diabetes mellitus on vascular albumin permeability and hypertrophy in 11-week-old Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) with and without 3 weeks of streptozotocin-induced diabetes. METHODS:Vascular albumin permeability was measured as...

journal_title：Journal of hypertension

authors： Hulthén UL,Rumble J,Cooper ME,Johnston CI

更新日期：1995-05-01 00:00:00

abstract：INTRODUCTION:Several renal denervation (RDN) systems are currently under investigation for treatment of hypertension by ablation of renal sympathetic nerves. The procedural efficacy of devices, however, is variable and incompletely understood. This study aimed at investigating procedural and anatomical predictors of RD...

journal_title：Journal of hypertension

authors： Wolf M,Hubbard B,Sakaoka A,Rousselle S,Tellez A,Jiang X,Kario K,Hohl M,Böhm M,Mahfoud F

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Excess dietary sodium has been linked to the development of hypertension and other cardiovascular diseases. In humans, the effects of sodium consumption on endothelial function have not been separated from the effects on blood pressure. The present study was designed to determine if dietary sodium intake aff...

journal_title：Journal of hypertension

authors： DuPont JJ,Greaney JL,Wenner MM,Lennon-Edwards SL,Sanders PW,Farquhar WB,Edwards DG

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Epidemiological investigations have demonstrated a close association between heavy alcohol consumption and hypertension. The mechanisms of this association, however, remain elusive. We studied the effects of alcohol withdrawal on blood pressure, hormonal parameters, and circulating markers of endothelial act...

journal_title：Journal of hypertension

authors： Soardo G,Donnini D,Varutti R,Milocco C,Basan L,Esposito W,Casaccio D,Isola M,Soldano F,Sechi LA

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:Similar to cancer, pulmonary arterial hypertension (PAH) is characterized by vascular remodeling, which leads to obliteration of the small pulmonary arteriole, with marked proliferation of pulmonary artery smooth muscle cells (PASMC) and/or endothelial cells dysfunction. Aberrant expression of tumor suppresso...

journal_title：Journal of hypertension

authors： Nie X,Dai Y,Tan J,Chen Y,Qin G,Mao W,Zou J,Chang Y,Wang Q,Chen J

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Some cases of pseudopheochromocytoma have been described among hypertensive patients with obstructive sleep apnea (OSA). This study examined whether a pathological rise of urinary metanephrines is a common feature in hypertensive OSA patients and, in such a case, whether the ventilation treatment during sleep...

journal_title：Journal of hypertension

authors： Gilardini L,Lombardi C,Redaelli G,Mattaliano P,Fanari P,Cornacchia M,Scacchi M,Mai S,Ferronato P,Parati G,Invitti C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:To investigate whether combined treatment with lisinopril, an angiotensin-converting enzyme (ACE) inhibitor and exercise training would have an additive effect in enhancing the capillary supply of the left ventricular (LV) myocardium in spontaneously hypertensive rats (SHR). DESIGN:Twelve-week-old male SHR ...

journal_title：Journal of hypertension

authors： Ziada AM,Hassan MO,Tahlilkar KI,Inuwa IM

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVES:Rapid growth velocity in early life may be a risk factor for obesity, elevated blood pressure, and adverse metabolic markers in childhood, but results are not consistent. We analysed the association between peak growth velocity during the first 2 years of life and blood pressure, fasting glucose and insulin ...

journal_title：Journal of hypertension

authors： Thiering E,Brüske I,Kratzsch J,Hoffmann B,Herbarth O,von Berg A,Schaaf B,Wichmann HE,Heinrich J,LISAplus Study Group.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To compare the prediction of mortality by ambulatory blood pressure monitoring and screening blood pressure measurements in a general population. DESIGN:A prospective cohort study. PATIENTS AND METHODS:We obtained blood pressure data for 1542 subjects (565 men and 977 women) aged > or = 40 years who were fo...

journal_title：Journal of hypertension

authors： Ohkubo T,Imai Y,Tsuji I,Nagai K,Watanabe N,Minami N,Itoh O,Bando T,Sakuma M,Fukao A,Satoh H,Hisamichi S,Abe K

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Salt sensitivity and the magnitude of systolic blood pressure have been linked to haptoglobin (Hp) polymorphism in normotensives. The aim of the present study was to investigate the indices of hypertension, the severity of complications and the occurrence of coronary and peripheral artery disease for the vari...

journal_title：Journal of hypertension

authors： Delanghe JR,Duprez DA,De Buyzere ML,Bergez BM,Callens BY,Leroux-Roels GG,Clement DL

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:Overweight/obesity in childhood is suggested to increase risk of hypertension later in life. However, few studies have assessed the effect of trajectories of weight status from childhood to adulthood on adult hypertension. The present study aimed to assess the relationship between weight status change from ch...

journal_title：Journal of hypertension

authors： Hou Y,Wang M,Yang L,Zhao M,Yan Y,Xi B

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To estimate the arterial blood pressure, left ventricular function and insulin secretion in alcoholics. DESIGN:We examined hospitalized patients between the second and seventh day of acute alcohol withdrawal and after a month of abstinence by 24 h ambulatory blood pressure monitoring, a standard oral glucose...

journal_title：Journal of hypertension

authors： Rajzer M,Kawecka-Jaszcz K,Czarnecka D,Dragan J,Betkowska B

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD:SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies....

journal_title：Journal of hypertension

authors： Øglaend B,Forman MR,Romundstad PR,Nilsen ST,Vatten LJ

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To compare estimates of mean population salt intake in North and South India derived from spot urine samples versus 24-h urine collections. METHODS:In a cross-sectional survey, participants were sampled from slum, urban and rural communities in North and in South India. Participants provided 24-h urine colle...

journal_title：Journal of hypertension

authors： Petersen KS,Johnson C,Mohan S,Rogers K,Shivashankar R,Thout SR,Gupta P,He FJ,MacGregor GA,Webster J,Santos JA,Krishnan A,Maulik PK,Reddy KS,Gupta R,Prabhakaran D,Neal B

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:In the BEtter control of BP in hypertensive pAtients monitored Using the HOTMAN sYstem study, we investigated whether utilizing noninvasive monitoring of hemodynamic parameters combined with a drug selection algorithm (integrated hemodynamic management - IHM) compared with conventional drug selection may imp...

journal_title：Journal of hypertension

authors： Fadl Elmula FE,Rebora P,Talvik A,Salerno S,Miszkowska-Nagórna E,Liu X,Heinpalu-Kuum M,Comotti T,Larstorp AC,Rostrup M,Świerblewska E,Valsecchi MG,Kjeldsen SE,Viigimaa M,Narkiewicz K,Parati G,Laurent S,BEtter control of

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies of the association between hypertension (HTN) and brain atrophy have shown reductions in prefrontal, temporal, and hippocampal volumes, and have identified thinner cortices across the cortical mantle. METHOD:In the current study, we followed 96 participants enrolled in the Baltimore ...

journal_title：Journal of hypertension

authors： Gonzalez CE,Pacheco J,Beason-Held LL,Resnick SM

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Patients with type-2 diabetes have a high prevalence of hypertension and show an elevated incidence of cardiovascular events and nephropathy. OBJECTIVES:Recent randomized trials of antihypertensive therapy providing information about cardiovascular and renal risk in diabetes, blood pressure goals and best s...

journal_title：Journal of hypertension

authors： Zanchetti A,Ruilope LM

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:The genetic background of orthostatic hypotension, an important risk factor for future cardiovascular morbidity and mortality, was investigated. DESIGN AND METHODS:The study subjects comprised 415 community-dwelling individuals, who were free from any cardiovascular complications, aged 50 years or older (mea...

journal_title：Journal of hypertension

authors： Tabara Y,Kohara K,Miki T

更新日期：2002-04-01 00:00:00

abstract：:The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 confirms ischemic heart disease and stroke as the leading cause of death and that hypertension is the main associated risk factor worldwide. How best to respond to the rising prevalence of hypertension in resource-deprived settings is a topic of ongo...

journal_title：Journal of hypertension

authors： Modesti PA,Agostoni P,Agyemang C,Basu S,Benetos A,Cappuccio FP,Ceriello A,Del Prato S,Kalyesubula R,O'Brien E,Kilama MO,Perlini S,Picano E,Reboldi G,Remuzzi G,Stuckler D,Twagirumukiza M,Van Bortel LM,Watfa G,Zhao D

更新日期：2014-05-01 00:00:00

abstract：:Current opinions on the relationships between erythrocyte sodium-lithium countertransport kinetics and primary hypertension, hyperlipidaemia and diabetic nephropathy are reviewed. Problems associated with the assay are analysed. Some possible mechanisms that could modify the kinetics of ion exchange are examined. The ...

journal_title：Journal of hypertension

authors： West IC,Rutherford PA,Thomas TH

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine whether pulse pressure is a risk factor for coronary artery disease using data from the MRC trial of treatment of mild hypertension, and whether the effect of anti-hypertensive drug therapy on pulse pressure may be a determinant of outcome in treated patients. METHODS:...

journal_title：Journal of hypertension

authors： Millar JA,Lever AF,Burke V

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To evaluate autonomic nervous function by power-spectral analysis of heart-rate variability in salt-sensitive and non-salt-sensitive patients with essential hypertension under the conditions of low and high salt intakes. DESIGN AND METHODS:The blood pressures, heart rates, and electrocardiogram R-R intervals...

journal_title：Journal of hypertension

authors： Minami J,Kawano Y,Ishimitsu T,Takishita S

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:To study blood pressure and antihypertensive drug treatment in subjects with contrasting family histories of hypertension. SUBJECTS AND METHODS:We grouped 520 offspring examined in 1990 (mean +/- SD age 36 +/- 7 years) according to their parents' blood pressure screened in 1963-1964 as offspring of two normo...

journal_title：Journal of hypertension

authors： Mo R,Omvik P,Lund-Johansen P

更新日期：1995-12-01 00:00:00