Geometric effects on OO bond scission of copper(II)-alkylperoxide complexes.

abstract：:The pH- and time-dependent reaction of the anticancer drug carboplatin, [Pt(cbdca-kappa(2)O,O')(NH(3))(2)] (cbdca=cyclobutane-1,1-dicarboxylate), with the tripeptides H-glyglymet-OH (glycylglycyl-L-methionine) and Ac-glyglymet-OH at 313 K was investigated by high-performance liquid chromatography, NMR and mass spectro...

journal_title：Journal of inorganic biochemistry

authors： Kleine M,Wolters D,Sheldrick WS

更新日期：2003-12-01 00:00:00

abstract：:An examination was made of the effects of tetrathiomolybdate (TTM), ammonium molybdate (AM), sodium sulphide, and two molybdo amino acids (cysteine-Mo, cysteine-Mo-S) on the distribution of Cu and Zn among proteins in extracts of the livers and kidneys of rats and sheep. Tetrathiomolybdate caused a shift in the chroma...

journal_title：Journal of inorganic biochemistry

authors： Allen JD,Gawthorne JM

更新日期：1987-11-01 00:00:00

abstract：:Computational studies were conducted to identify the favourable formation of the inclusion complex of chloramphenicol with cyclodextrins. The results of molecular docking and molecular dynamics predicted the strongest interaction of chloramphenicol with γ-cyclodextrin. Further, the inclusion complex of chloramphenicol...

journal_title：Journal of inorganic biochemistry

authors： Gannimani R,Ramesh M,Mtambo S,Pillay K,Soliman ME,Govender P

更新日期：2016-04-01 00:00:00

abstract：:The bacterial cytochrome c peroxidases contain an electron-transferring haem c (E) and a peroxidatic haem c (P). Many are isolated in an inactive oxidised state. Reduction of the E haem promotes Ca(2+)-dependent spin state and coordination changes at the P haem rendering it accessible to ligand. Recent crystallographi...

journal_title：Journal of inorganic biochemistry

authors： Pettigrew GW,Echalier A,Pauleta SR

更新日期：2006-04-01 00:00:00

abstract：:Vitamin K3-thiosemicarbazone (C12H11N3NaO4S2 x 5H2O, abbreviated as VT), a new Schiff base derivative, has been synthesized. Its crystal structure, determined by X-ray diffraction, is triclinic, space group P1. We have also prepared five novel complexes of VT with transition metals: [M(VT)(2)2H2O] x nH2O, (n = 1 and 2...

journal_title：Journal of inorganic biochemistry

authors： Li QX,Tang HA,Li YZ,Wang M,Wang LF,Xia CG

更新日期：2000-01-30 00:00:00

abstract：:Shape analysis of coordination complexes is well-suited to evaluate the subtle distortions in the trigonal bipyramidal (TBPY-5) geometry of vanadium coordinated in the active site of phosphatases and characterized by X-ray crystallography. Recent studies using the tau (τ) analysis support the assertion that vanadium i...

journal_title：Journal of inorganic biochemistry

authors： Sánchez-Lombardo I,Alvarez S,McLauchlan CC,Crans DC

更新日期：2015-06-01 00:00:00

abstract：:In this paper, antineoplastic activities of protein-conjugated silver sulfide nano-crystals with different shapes were described in detail. Transmission electron microscope analysis demonstrated that stable and well-disperse protein-conjugated silver sulfide nano-particles, nano-rods, and nano-wires could be prepared ...

journal_title：Journal of inorganic biochemistry

authors： Wang HJ,Yang L,Yang HY,Wang K,Yao WG,Jiang K,Huang XL,Zheng Z

更新日期：2010-01-01 00:00:00

abstract：:Maintenance of cellular iron homeostasis demands the coordination of iron uptake, intracellular storage, and utilization. Recent investigations suggest that a single genetic regulatory system orchestrates the expression of proteins with central importance for all three aspects of cellular iron metabolism at the level ...

journal_title：Journal of inorganic biochemistry

authors： Kühn LC,Hentze MW

更新日期：1992-08-15 00:00:00

abstract：:Aluminum, the most abundant neurotoxic metal in our biosphere, has been implicated in the etiology of several neurodegenerative disorders including Alzheimer's disease (AD). To further understand aluminum's influence on gene expression, we examined total messenger RNA levels in untransformed human neural cells exposed...

journal_title：Journal of inorganic biochemistry

authors： Lukiw WJ,Percy ME,Kruck TP

更新日期：2005-09-01 00:00:00

abstract：:The novel steroidal carrier ligand 17-α-[4'-ethynyl-dimethylbenzylamine]-17-β-testosterone (ET-dmba 1) and the steroid--C,N-chelate platinum(II) derivatives [Pt(ET-dmba)Cl(L)] (L = DMSO (2) and PTA (3; PTA =1,3,5-triaza-7-phosphaadamantane)) have been prepared. Values of IC(50) were calculated for the new platinum com...

journal_title：Journal of inorganic biochemistry

authors： Ruiz J,Rodríguez V,Cutillas N,Espinosa A,Hannon MJ

更新日期：2011-04-01 00:00:00

abstract：:Aqueous solutions of the four highest vanadium oxidation states exhibit four diverse colors, which only hint at the diverse reactions that these ions can undergo. Cationic vanadium ions form complexes with ligands; anionic vanadium ions form complexes with ligands and self-react to form isopolyanions. All vanadium spe...

journal_title：Journal of inorganic biochemistry

authors： Kustin K

更新日期：2015-06-01 00:00:00

abstract：:Bovine calmodulin, spin-labeled at tyrosine-99, has been utilized in electron paramagnetic resonance (EPR) studies to investigate calmodulin interactions with Ca(II), Cd(II), and Mg(II). The addition of either Ca(II) or Cd(II) to apo-calmodulin results in a complex capable of activating target enzymes, such as 3', 5'-...

journal_title：Journal of inorganic biochemistry

authors： You GF,Buccigross JM,Nelson DJ

更新日期：1990-02-01 00:00:00

abstract：:A simple methodology giving access to the metal-free corroles of trans-A2B type, 5,15-bis(pentafluorophenyl)-10-{3-[2-(pyridin-4-yl)vinyl]phenyl}corrole and 5,15-bis(pentafluorophenyl)-10-{4-[2-(pyridin-4-yl)vinyl]phenyl}corrole, and to the corresponding bipyridyl platinum(II) complexes is described. These new positio...

journal_title：Journal of inorganic biochemistry

authors： Iglesias BA,Barata JFB,Pereira PMR,Girão H,Fernandes R,Tomé JPC,Neves MGPMS,Cavaleiro JAS

更新日期：2015-12-01 00:00:00

abstract：:The potential of hyphenated techniques based on a combination of microbore reversed-phase (RP) HPLC or capillary zone electrophoresis (CZE) with inductively coupled plasma (ICP) or electrospray (ES) mass spectrometry (MS) was demonstrated for the characterization of metal complexes with metallothionein in rat liver an...

journal_title：Journal of inorganic biochemistry

authors： Połec K,Peréz-Calvo M,García-Arribas O,Szpunar J,Ribas-Ozonas B,Lobinski R

更新日期：2002-01-15 00:00:00

abstract：:Cultured rat hepatoma cells (HTC-cells) were used to study the transfer of copper from a well-defined medium to and across the cell membrane and particularly the role of albumin in this process. HTC-cells, maintained in a minimal salt-glucose medium, accumulated far more copper than when maintained in the same medium,...

journal_title：Journal of inorganic biochemistry

authors： van den Berg GJ,van den Hamer CJ

更新日期：1984-10-01 00:00:00

abstract：:The reaction of thiosemicarbazones (TSCs) with [Au(I)(THT)Cl], THT=tetrahydrothiophene, has been investigated. The resulting gold(I) complexes have been characterized by a range of spectroscopic techniques: NMR spectroscopy, mass spectrometry, microanalysis and infrared spectroscopy. The in vitro antimalarial data for...

journal_title：Journal of inorganic biochemistry

authors： Khanye SD,Smith GS,Lategan C,Smith PJ,Gut J,Rosenthal PJ,Chibale K

更新日期：2010-10-01 00:00:00

abstract：:Measurement and interpretation of the EXAFS associated with the K-absorption edge of zinc atoms in sheep liver metallothionein indicate that the primary coordination shell of each of these metal atoms comprises four sulphur atoms, with the Zn-S distance being 2.29 +/- 0.02 A. ...

journal_title：Journal of inorganic biochemistry

authors： Garner CD,Hasain SS,Bremner I,Bordas J

更新日期：1982-06-01 00:00:00

abstract：:The pre-steady-state reduction of cytochrome P450 (P450) 2B4 by P450 reductase (reductase) was modeled by assuming that an equilibrium between three catalytic conformers of P450 regulates the multi-phasic reduction of the enzyme. This model was compared to a model of reduction involving a minimum number of phases. Bas...

journal_title：Journal of inorganic biochemistry

authors： Reed JR,Hollenberg PF

更新日期：2003-11-01 00:00:00

abstract：:The advantages of systems with Ag nanoparticles and their assemblies for surface-enhanced resonance Raman scattering (SERRS) spectral investigation, detection and determination of porphyrin species are demonstrated. SERRS spectral detection limits of the testing porphyrin species (including porphyrin aggregates) in th...

journal_title：Journal of inorganic biochemistry

authors： Vlcková B,Smejkal P,Michl M,Procházka M,Mojzes P,Lednický F,Pfleger J

更新日期：2000-04-01 00:00:00

abstract：:Nickel-containing carbon monoxide dehydrogenases, acetyl-CoA synthases, nickel-iron hydrogenases, and diron hydrogenases are distinct metalloenzymes yet they share a number of important characteristics. All are O(2)-sensitive, with active-sites composed of iron and/or nickel ions coordinated primarily by sulfur ligand...

journal_title：Journal of inorganic biochemistry

authors： Lindahl PA

更新日期：2012-01-01 00:00:00

abstract：:Preparations of cis- and trans-platinum(II) complexes of diethyl (pyridin-4-ylmethyl)phosphate (4-pmOpe) have been described. These complexes were identified and characterized by far-IR, 1H NMR, 13C NMR, 31P NMR and 195Pt NMR and microanalyses. The crystal and molecular structure of trans-platinum(II) complex i.e., tr...

journal_title：Journal of inorganic biochemistry

authors： Kalinowska U,Matławska K,Checińska L,Domagała M,Kontek R,Osiecka R,Ochocki J

更新日期：2005-10-01 00:00:00

abstract：:To investigate the structure-activity relationship of vanadium complexes in inhibiting protein tyrosine phosphatase1B (PTP1B), eight mixed-ligand oxovanadium(IV) complexes, [V(IV)O(SalAla)(NN)] (H(2)SalAla for salicylidene alanine, NN for N,N'-donor heterocyclic base, namely, 2,2'-bipyridine (bpy, 1), 1,10-phenanthrol...

journal_title：Journal of inorganic biochemistry

authors： Lu L,Yue J,Yuan C,Zhu M,Han H,Liu Z,Guo M

更新日期：2011-10-01 00:00:00

abstract：:The resonance Raman spectra of native stellacyanin and its Ni(II) derivative has been investigated. Raman intensity as a function of the exciting frequency shows minima at about 440--460 nm. Moreover, the resonance Raman spectra of the Ni(II) derivative indicate similar symmetry and nature of ligands, namely, one cyst...

journal_title：Journal of inorganic biochemistry

authors： Musci G,Desideri A,Morpurgo L,Tosi L

更新日期：1985-02-01 00:00:00

abstract：:Cytochrome c(551) from Pseudomonas aeruginosa is a monomeric redox protein of 82 amino-acid residues, involved in dissimilative denitrification as the physiological electron donor of cd(1) nitrite reductase. The distribution of charged residues on the surface of c(551) is very anisotropic: one side is richer in acidic...

journal_title：Journal of inorganic biochemistry

authors： Cutruzzolà F,Arese M,Ranghino G,van Pouderoyen G,Canters G,Brunori M

更新日期：2002-02-01 00:00:00

abstract：:Chromium(VI) compounds (e.g. chromates) are cytotoxic, mutagenic, and potentially carcinogenic. The reduction of Cr(VI) can yield reactive intermediates such as Cr(V) and reactive oxygen species. Bronchial epithelial cells are the primary site of pulmonary exposure to inhaled Cr(VI) and are the primary cells from whic...

journal_title：Journal of inorganic biochemistry

authors： Borthiry GR,Antholine WE,Myers JM,Myers CR

更新日期：2008-07-01 00:00:00

abstract：:The substitution of tetradentate bispidine ligands with rhodamine and cyanine dye molecules, coupled to an amine donor, forming an amide as potential fifth donor, is described. Bispidines are known to lead to very stable Cu(II) complexes, and the coordination to Cu(II) was expected to efficiently quench the fluorescen...

journal_title：Journal of inorganic biochemistry

authors： Brox D,Comba P,Herten DP,Kimmle E,Morgen M,Rühl CL,Rybina A,Stephan H,Storch G,Wadepohl H

更新日期：2015-07-01 00:00:00

abstract：:Casiopeinas is the generic name of a group of copper chelated complexes designed to be used as antineoplastic. Some of these compounds have shown promising results, and in fact, one of them named Casiopeina III-ia has completed preclinical trials and is ready to start clinical phase I in Mexico. As part of the tests t...

journal_title：Journal of inorganic biochemistry

authors： Serment-Guerrero J,Bravo-Gomez ME,Lara-Rivera E,Ruiz-Azuara L

更新日期：2017-01-01 00:00:00

abstract：:Genomics projects have elucidated several genes that encode protein sequences. Subsequently, the advent of the proteomics age has enabled the synthesis and 3D structure determination for these protein sequences. Some of these proteins incorporate metal atoms but it is often not known whether they are metal-binding pro...

journal_title：Journal of inorganic biochemistry

authors： González-Díaz H,Sánchez-González A,González-Díaz Y

更新日期：2006-07-01 00:00:00

abstract：:Biological studies on [Fe(L)2](NO3).0.5H2O (1), [Fe(L)2][PF6] (2), [Co(L)2](NCS) (3), [Ni(HL)2]Cl2.3H2O (4) and Cu(L)(NO3) (5), where HL=C7H8N4S, pyridine-2-carbaldehyde thiosemicarbazone, have been carried out. The crystal structure of compound 3 has been solved. It consists of discrete monomeric cationic entities co...

journal_title：Journal of inorganic biochemistry

authors： García-Tojal J,García-Orad A,Díaz AA,Serra JL,Urtiaga MK,Arriortua MI,Rojo T

更新日期：2001-04-01 00:00:00

abstract：:Neuronal nitric oxide synthase (nNOS) generates superoxide, particularly at sub-optimal l-arginine (l-Arg) substrate concentrations. Heat shock protein 90 (Hsp90) was reported to inhibit superoxide generation from nNOS protein. However, commercially available Hsp90 product from bovine brain tissues with unspecified Hs...

journal_title：Journal of inorganic biochemistry

authors： Zheng H,Weaver JM,Feng C

更新日期：2021-01-01 00:00:00