当前位置： SCI文献检索 > JOURNAL OF INORGANIC BIOCHEMISTRY期刊下所有文献 > New platinum(II)-bipyridyl corrole complexes: Synthesis, characterization and binding studies with DNA and HSA.

New platinum(II)-bipyridyl corrole complexes: Synthesis, characterization and binding studies with DNA and HSA.

Abstract：

:A simple methodology giving access to the metal-free corroles of trans-A2B type, 5,15-bis(pentafluorophenyl)-10-{3-[2-(pyridin-4-yl)vinyl]phenyl}corrole and 5,15-bis(pentafluorophenyl)-10-{4-[2-(pyridin-4-yl)vinyl]phenyl}corrole, and to the corresponding bipyridyl platinum(II) complexes is described. These new positional isomers were fully characterized and spectroscopic studies demonstrated the ability of Pt(II)-corrole complexes to establish non-covalent interactions with calf-thymus DNA (ct-DNA) and human serum albumin (HSA). Additionally, gel electrophoresis experiments demonstrated that Pt(II)-corrole complexes are able to bind plasmid pMT123 DNA, inducing alterations on its secondary structure.

journal_name

J Inorg Biochem

journal_title

Journal of inorganic biochemistry

authors

Iglesias BA,Barata JFB,Pereira PMR,Girão H,Fernandes R,Tomé JPC,Neves MGPMS,Cavaleiro JAS

doi

10.1016/j.jinorgbio.2015.08.016

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

32-41

eissn

0162-0134

issn

1873-3344

pii

S0162-0134(15)30062-3

journal_volume

153

pub_type

杂志文章

相关文献

JOURNAL OF INORGANIC BIOCHEMISTRY文献大全
  • Drug-metal interactions: copper(II) complex of the antidiabetic drug acetohexamide and pyridine.

    abstract：:The preparation, spectral properties, and crystal structure of a copper(II) complex of 4-acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide, which is known as acetohexamide, and pyridine are reported. The complex Cu(AH)2(py)2, where AH = acetohexamide and py = pyridine, was prepared and characterized by X-ray and ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(90)84012-e

    authors： Pezeshk A,Pezeshk V

    更新日期：1990-03-01 00:00:00

  • Copper transfer from Rhus vernicifera laccase.

    abstract：:Tree laccase, a multi-copper oxidase, has been studied as a copper donor in conjunction with the demetalated forms of three blue copper proteins. Copper transfer could be observed under reducing conditions in the absence of air. Only about 10% of the total copper in laccase could be transferred regardless of the amoun...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(91)80017-c

    authors： Meadows KA,Morie-Bebel MM,McMillin DR

    更新日期：1991-03-01 00:00:00

  • Dinuclear macrocyclic polyamine zinc(II) complexes: syntheses, characterization and their interaction with plasmid DNA.

    abstract：:The syntheses, characteristics of dinuclear macrocyclic polyamine zinc complexes and their interaction with plasmid DNA are reported. The two cyclen (1,4,7,10-tetraazacyclododecane) moieties are bridged by rigid and flexible linkages. The crystal structures of Zn2C27H43N8O15Cl4 [5c.(ClO4)3.2H2O] and Zn2C30H43N10O13Cl3...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.05.008

    authors： Xiang QX,Zhang J,Liu PY,Xia CQ,Zhou ZY,Xie RG,Yu XQ

    更新日期：2005-08-01 00:00:00

  • 1H NMR and UV-Vis spectroscopic characterization of sulfonamide complexes of nickel(II)-carbonic anhydrase. Resonance assignments based on NOE effects.

    abstract：:The binding of acetazolamide, p-fluorobenzensulfonamide, p-toluenesulfonamide, and sulfanilamide to nickel(II)-substituted carbonic anhydrase II has been studied by 1H NMR and electronic absorption spectroscopies. These inhibitors bind to the metal ion forming 1:1 complexes and their affinity constants were determined...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(92)84012-c

    authors： Moratal JM,Martinez-Ferrer MJ,Jiménez HR,Donaire A,Castells J,Salgado J

    更新日期：1992-03-01 00:00:00

  • Platinum-based drugs and proteins: reactivity and relevance to DNA adduct formation.

    abstract：:The mechanism of action of clinically used Pt-based drugs is through the formation of stable DNA adducts occurring at the nitrogen in position 7 of guanine (N7) and involving one or two spatially closed residues. Nevertheless, proteins can represent alternative targets since in particular sulfur groups, present in cys...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2013.01.007

    authors： Pinato O,Musetti C,Farrell NP,Sissi C

    更新日期：2013-05-01 00:00:00

  • Biochemical characterization of phospholipases C from Coffea arabica in response to aluminium stress.

    abstract：:Signal transduction in plants determines their successful adaptation to diverse stress factors. Our group employed suspension cells to study the phosphoinositide pathway, which is triggered by aluminium stress. We investigated about members of the PI-specific phospholipase C (PLC) family and evaluated their transcript...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.110951

    authors： González-Mendoza VM,Sánchez-Sandoval ME,Munnik T,Hernández-Sotomayor SMT

    更新日期：2020-03-01 00:00:00

  • Effect of redox partner binding on CYP101D1 conformational dynamics.

    abstract：:We have compared the thermodynamics of substrate and redox partner binding of P450cam to its close homologue, CYP101D1, using isothermal titration calorimetry (ITC). CYP101D1 binds camphor about 10-fold more weakly than P450cam which is consistent with the inability of camphor to cause a complete low- to high-spin shi...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.02.013

    authors： Batabyal D,Poulos TL

    更新日期：2018-06-01 00:00:00

  • Aqueous vanadium ion dynamics relevant to bioinorganic chemistry: A review.

    abstract：:Aqueous solutions of the four highest vanadium oxidation states exhibit four diverse colors, which only hint at the diverse reactions that these ions can undergo. Cationic vanadium ions form complexes with ligands; anionic vanadium ions form complexes with ligands and self-react to form isopolyanions. All vanadium spe...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/j.jinorgbio.2014.12.009

    authors： Kustin K

    更新日期：2015-06-01 00:00:00

  • Crystal packing and hydrogen bonding in platinum(II) nucleotide complexes: X-ray crystal structure of [Pt(MeSCH(2)CH(2)SMe)(5'-GMP-N7)(2)].6H(2)O.

    abstract：:We have synthesised the complex [Pt(CH(3)SCH(2)CH(2)SCH(3))(5'-GMP-N7)(2)].6H(2)O (1), where 5'-GMP is 5'-guanosine monophosphate, and determined its X-ray crystal structure. Pt(II) adopts a square-planar geometry in which the bases are coordinated head-to-tail (HT) in the Delta configuration. The nucleotide conformat...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(01)00351-8

    authors： Djuran MI,Milinkovic SU,Habtemariam A,Parsons S,Sadler PJ

    更新日期：2002-02-01 00:00:00

  • A dinuclear zinc(II) complex of a new unsymmetric ligand with an N(5)O(2) donor set: a structural and functional model for the active site of zinc phosphoesterases.

    abstract：:The dinuclear complex [Zn(2)(DPCPMP)(pivalate)](ClO4), where DPCPMP is the new unsymmetrical ligand [2-(N-(3-((bis((pyridin-2-yl)methyl)amino)methyl)-2-hydroxy-5-methylbenzyl)-N-((pyridin-2-yl)methyl)amino)acetic acid], has been synthesized and characterized. The complex is a functional model for zinc phosphoesterases...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2013.08.001

    authors： Das B,Daver H,Pyrkosz-Bulska M,Persch E,Barman SK,Mukherjee R,Gumienna-Kontecka E,Jarenmark M,Himo F,Nordlander E

    更新日期：2014-03-01 00:00:00

  • New insights into the chemical structure and composition of the pentavalent antimonial drugs, meglumine antimonate and sodium stibogluconate.

    abstract：:The chemical structures of the pentavalent antimonial drugs, meglumine antimonate (MA) and sodium stibogluconate (SSG), were re-evaluated using electrospray ionization mass spectrometry (ESI-MS) and osmolarity measurements. Both MA and SSG were found to contain 1:1, 1:2, 2:2 and 2:3 Sb(V)-ligand complexes. ESI-MS anal...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2007.10.010

    authors： Frézard F,Martins PS,Barbosa MC,Pimenta AM,Ferreira WA,de Melo JE,Mangrum JB,Demicheli C

    更新日期：2008-04-01 00:00:00

  • Bis(L-cysteinato)gold(I): chemical characterization and identification in renal cortical cytoplasm.

    abstract：:L-Cysteinatogold(I) was prepared by the reaction of L-cysteine with KAuBr4 in acidic media and its solubility determined from pH 4 to 10. The solubility at pH 7.4 and 37 degrees C is 1 microM. In the presence of excess cysteine, the solubility increases because of formation of bis(L-cysteinato)gold(I). The equilibrium...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(00)80198-1

    authors： Shaw CF 3rd,Schmitz G,Thompson HO,Witkiewicz P

    更新日期：1979-07-01 00:00:00

  • Low-dimensional compounds containing bioactive ligands. Part VI: Synthesis, structures, in vitro DNA binding, antimicrobial and anticancer properties of first row transition metal complexes with 5-chloro-quinolin-8-ol.

    abstract：:A series of new 3d metal complexes with 5-chloro-quinolin-8-ol (ClQ), [Mn(ClQ)2] (1), [Fe(ClQ)3] (2), [Co(ClQ)2(H2O)2] (3), [Ni(ClQ)2(H2O)2] (4), [Cu(ClQ)2] (5), [Zn(ClQ)2(H2O)2] (6), [Mn(ClQ)3]·DMF (7) and [Co(ClQ)3]·DMF·(EtOH)0.35 (8) (DMF=N,N-dimethylformamide), has been synthesized and characterized by elemental a...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2015.10.015

    authors： Potočňák I,Vranec P,Farkasová V,Sabolová D,Vataščinová M,Kudláčová J,Radojević ID,Čomić LR,Markovic BS,Volarevic V,Arsenijevic N,Trifunović SR

    更新日期：2016-01-01 00:00:00

  • Effect of molybdenum treatments on the distribution of Cu and metallothionein in tissue extracts from rats and sheep.

    abstract：:An examination was made of the effects of tetrathiomolybdate (TTM), ammonium molybdate (AM), sodium sulphide, and two molybdo amino acids (cysteine-Mo, cysteine-Mo-S) on the distribution of Cu and Zn among proteins in extracts of the livers and kidneys of rats and sheep. Tetrathiomolybdate caused a shift in the chroma...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(87)80002-8

    authors： Allen JD,Gawthorne JM

    更新日期：1987-11-01 00:00:00

  • Quinoline antimalarials decrease the rate of beta-hematin formation.

    abstract：:The strength of inhibition of beta-hematin (synthetic hemozoin or malaria pigment) formation by the quinoline antimalarial drugs chloroquine, amodiaquine, quinidine and quinine has been investigated as a function of incubation time. In the assay used, beta-hematin formation was brought about using 4.5M acetate, pH 4.5...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.04.013

    authors： Egan TJ,Ncokazi KK

    更新日期：2005-07-01 00:00:00

  • Vanadium-catalyzed chlorination under molecular oxygen.

    abstract：:A catalytic chlorination of ketones was performed by using a vanadium catalyst in the presence of Bu4NI and AlCl3 under atmospheric molecular oxygen. This catalytic chlorination could be applied to the chlorination of alkenes to give the corresponding vic-dichlorides. AlCl3 was found to serve as both a Lewis acid and ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2015.01.015

    authors： Moriuchi T,Fukui Y,Kato S,Kajikawa T,Hirao T

    更新日期：2015-06-01 00:00:00

  • In vitro and in vivo antitumor activity of a novel carbonyl ruthenium compound, the ct-[RuCl(CO)(dppb)(bipy)]PF-6[dppb=1,4-bis(diphenylphosphine)butane and bipy=2,2'-bipyridine].

    abstract：:This study performed in vitro and in vivo biological assays of the ruthenium (II) compound ct-[RuCl(CO)(dppb)(bipy)]PF6 (where, dppb=1,4-bis(diphenylphosphine)butane and bipy=2,2'-bipyridine). The cytotoxic activity of this compound was evaluated against different tumor cell lines (HeLa, human cervical adenocarcinoma;...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2016.08.010

    authors： Carnizello AP,Barbosa MI,Martins M,Ferreira NH,Oliveira PF,Magalhães GM,Batista AA,Tavares DC

    更新日期：2016-11-01 00:00:00

  • Heat shock protein 90α increases superoxide generation from neuronal nitric oxide synthases.

    abstract：:Neuronal nitric oxide synthase (nNOS) generates superoxide, particularly at sub-optimal l-arginine (l-Arg) substrate concentrations. Heat shock protein 90 (Hsp90) was reported to inhibit superoxide generation from nNOS protein. However, commercially available Hsp90 product from bovine brain tissues with unspecified Hs...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2020.111298

    authors： Zheng H,Weaver JM,Feng C

    更新日期：2021-01-01 00:00:00

  • New photosensitive nanometric graphite oxide composites as antimicrobial material with prolonged action.

    abstract：:A new conjugate material based on partially reduced graphite oxide (rGO), silver nanoparticles (Ag), and bis(lysinato)zirconium(IV) phthalocyanine complex (ZrPc) was obtained. Its optical properties (absorption and photoluminescence) after dispersion in solvents were examined. The antimicrobial properties were tested ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2016.02.019

    authors： Gerasymchuk Y,Lukowiak A,Wedzynska A,Kedziora A,Bugla-Ploskonska G,Piatek D,Bachanek T,Chernii V,Tomachynski L,Strek W

    更新日期：2016-06-01 00:00:00

  • Deletion analysis of the rodent selenoprotein W promoter.

    abstract：:To identify regulatory elements in the rat selenoprotein W (SeW) promoter, 2090, 1265, 741, and 404 base pair truncations of genomic DNA lying immediately upstream of the SeW coding sequence were cloned into a luciferase reporter vector (pGL3-Basic from Promega, Madison, WI, USA). 3656 and 406 base pair mouse SeW prom...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.06.035

    authors： Hooven LA,Vorachek WR,Bauman AB,Butler JA,Ream LW,Whanger PD

    更新日期：2005-10-01 00:00:00

  • Stopped-flow studies of cytochrome oxidase reconstituted into liposomes: proton pumping and control of activity.

    abstract：:The transient kinetics of proton pumping and the electron transfer properties of cytochrome oxidase inserted into small unilamellar vesicles have been investigated by stopped-flow spectrophotometry. In the presence of valinomycin, proton pumping and cytochrome c oxidation by cytochrome oxidase are synchronous up to ra...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(85)85048-0

    authors： Brunori M,Antonini G,Colosimo A,Malatesta F,Sarti P,Jones MG,Wilson MT

    更新日期：1985-03-01 00:00:00

  • Replacement of the heme axial lysine as a test of conformational adaptability in the truncated hemoglobin THB1.

    abstract：:Amino acid replacement is a useful strategy to assess the roles of axial heme ligands in the function of native heme proteins. THB1, the protein product of the Chlamydomonas reinhardtii THB1 gene, is a group 1 truncated hemoglobin that uses a lysine residue in the E helix (Lys53, at position E10 by reference to myoglo...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.110824

    authors： Nye DB,Johnson EA,Mai MH,Lecomte JTJ

    更新日期：2019-12-01 00:00:00

  • A ruthenium(II) complex containing a p-cresol group induces apoptosis in human cervical carcinoma cells through endoplasmic reticulum stress and reactive oxygen species production.

    abstract：:The chemical structures of Ru (II) complexes are known to affect their cellular behavior and toxicity. In this study, three new luminescent Ru (II) complexes, [Ru(bpy)2(HIPMP)](ClO4)2 (Ru1, bpy = 2,2'-bipyridine, HIPMP = 2-(1H-imidazo-[4,5-f] [1,10] phenanthrolin-2-yl)-4-methylphenol), [Ru(phen)2(HIPMP)](ClO4)2 (Ru2, ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.11.015

    authors： Xu L,Zhang PP,Fang XQ,Liu Y,Wang JQ,Zhou HZ,Chen ST,Chao H

    更新日期：2019-02-01 00:00:00

  • N-acetylaspartate complexes with calcium and lanthanide ions.

    abstract：:N-acetylaspartate (NAA) is the one of the most prominent resonances observed in the solvent-suppressed NMR spectrum of the human brain. Although it is present in the brain at about 10 mM, its precise metabolic function is still unclear, We have examined the NAA as a potential chelator for divalent metal ions such as C...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(94)00132-t

    authors： Rubin Y,Connelly GP,Lenkinski RE

    更新日期：1995-10-01 00:00:00

  • Complexation of U(VI) with highly phosphorylated protein, phosvitin A vibrational spectroscopic approach.

    abstract：:The complexation of uranium(VI) to variant functional groups of the highly phosphorylated protein phosvitin in aqueous solution was investigated by attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy. For the verification of the affinity of the actinyl ions to carboxyl and phosphate groups ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2010.03.004

    authors： Li B,Raff J,Barkleit A,Bernhard G,Foerstendorf H

    更新日期：2010-07-01 00:00:00

  • Metal complexes of anhydrotetracycline. 2. Absorption and circular dichroism study of Mg(II), Al(III), and Fe(III) complexes. Possible influence of the Mg(II) complex on the toxic side effects of tetracycline.

    abstract：:Anhydrotetracycline (AHTC) is the major toxic decomposition product of the antibiotic tetracycline. The complexation of AHTC to Mg(II), Al(III), and Fe(III) was studied in aqueous medium using absorption and circular dichroism measurements. The study of the Mg(II)-AHTC interactions at pH 7 indicated the formation of t...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(95)00017-i

    authors： Machado FC,Demicheli C,Garnier-Suillerot A,Beraldo H

    更新日期：1995-11-15 00:00:00

  • Application of a self-modeling curve resolution approach to the study of solvent effects on the acid-base and copper (II)-complexing behavior of polyuridylic acid.

    abstract：:The solvent effect on the acid-base and complexation behavior of the homopolynucleotide polyuridylic acid (poly(U)) has been studied by means of potentiometric and spectrometric titrations (circular dichroism and UV-VIS) in water and in 30 and 50% (v/v) dioxane-water media. The potentiometric studies revealed the abse...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(95)00211-1

    authors： de Juan A,Fonrodona G,Gargallo R,Izquierdo-Ridorsa A,Tauler R,Casassas E

    更新日期：1996-08-15 00:00:00

  • Synthesis, crystal structure and nuclease activity of a Schiff base copper(II) complex.

    abstract：:A new Schiff base copper(II) complex, Cu(o-VANAHE)(2) (o-VANAHE = 2-(o-vanillinamino)-1-hydroxyethane), has been synthesized and characterized. Single crystal X-ray diffraction results suggest that this complex structure belongs to triclinic crystal system, space group P1 with the following crystallographic parameters...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.01.017

    authors： Li LZ,Zhao C,Xu T,Ji HW,Yu YH,Guo GQ,Chao H

    更新日期：2005-05-01 00:00:00

  • Stability constant determination of sulfur and selenium amino acids with Cu(II) and Fe(II).

    abstract：:Sulfur- and selenium-containing amino acids are of great biological importance, but their metal-binding properties with biologically-relevant metal ions are not well investigated. Stability constants of the methionine, selenomethionine, methylcysteine, and methylselenocysteine with Cu(II) and Fe(II) were determined by...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.03.001

    authors： Murphy JM,Gaertner AAE,Williams T,McMillen CD,Powell BA,Brumaghim JL

    更新日期：2019-06-01 00:00:00

  • Synthesis and characterization of water-insoluble and water-soluble dibutyltin(IV) porphinate complexes based on the tris(pyridinyl)porphyrin moiety, their anti-tumor activity in vitro and interaction with DNA.

    abstract：:The water-insoluble and water-soluble organotin(IV)porphinate complexes based on the tris-(4-pyridinyl)porphyrin and tris(N-methyl-4-pyridiniumyl)porphyrin moieties were synthesized and characterized by elemental analysis, (1)H NMR, IR and electrospray ionization mass spectra. The in vitro activity of the compounds ag...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(02)00369-0

    authors： Han G,Yang P

    更新日期：2002-07-25 00:00:00