Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity.

abstract：:Copper based nanoparticles (Cu-based NPs) of different compositions and sizes have been hydrothermally synthesized by varying the reaction time in the presence of the biocompatible surfactants polyoxyethylene (20) sorbitan laurate (Tween 20) and polyethylene glycol 8000 (PEG 8000). Effective control of the above synth...

journal_title：Journal of inorganic biochemistry

authors： Giannousi K,Lafazanis K,Arvanitidis J,Pantazaki A,Dendrinou-Samara C

更新日期：2014-04-01 00:00:00

abstract：:A study has been performed of the kinetics and equilibria involved in complex formation between the macrocyclic polyamine 2,5,8,11-tetraaza[12]-[12](2,9)[1,10]-phenanthrolinophane (Neotrien) and Cu(II) in acidic aqueous solution and ionic strength 0.5 M (NaCl), by means of the stopped-flow method and UV spectrophotome...

journal_title：Journal of inorganic biochemistry

authors： Biver T,Secco F,Tinè MR,Venturini M

更新日期：2004-01-01 00:00:00

abstract：:In this work we report a series of Cu(II) complexes [Cu(N-N)2(X)]+, (N-N=substituted 1,10-phenanthroline derivatives and X=Cl- or NO3-), with tunable E1/2 for electrochemical reduction [CuII(N-N)2(X)]++1e-⇌[CuI(N-N)2]+X-. The disproportion of O2•- was explored in presence of the electro-generated species [CuI(N-N)2]+ ...

journal_title：Journal of inorganic biochemistry

authors： Manzanera-Estrada ME,Cruz-Ramírez M,Flores-Alamo M,Gracia Y Jiménez JM,Galindo-Murillo R,García-Ramos JC,Ruiz-Azuara L,Ortiz-Frade L

更新日期：2017-10-01 00:00:00

abstract：:The proton equilibrium in aqueous surfactant solutions of hemin, (PPIX)Fe(H2O)+2, involving the propionic acid groups is reported (PPIX = protoporphyrinato IX). The surfactant used are sodium dodecyl sulphate (SDS), triton X-100 (TX-100) and hexadecyl trimethylammonium bromide (CTAB). The pKa values, determined spectr...

journal_title：Journal of inorganic biochemistry

authors： Das DK,Medhi OK

更新日期：1998-05-01 00:00:00

abstract：:The preparation, spectral properties, and crystal structure of a copper(II) complex of 4-acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide, which is known as acetohexamide, and pyridine are reported. The complex Cu(AH)2(py)2, where AH = acetohexamide and py = pyridine, was prepared and characterized by X-ray and ...

journal_title：Journal of inorganic biochemistry

authors： Pezeshk A,Pezeshk V

更新日期：1990-03-01 00:00:00

abstract：:Citrate occurs at about 0.1 mM in blood plasma and is the most likely small molecule plasma binder of both Al3+ and Fe3+. This paper assesses published stability constants for citrate binding to each metal ion. From pH 2 to 5 Al3+ forms a neutral complex with citrate that may be absorbed into the body in the upper reg...

journal_title：Journal of inorganic biochemistry

authors： Martin RB

更新日期：1986-10-01 00:00:00

abstract：:Copper(II) and zinc(II) complexes of the peptides Ac-HisValHis-NH2 and Ac-HisValGlyAsp-NH2 related to the active site of the enzyme CuZnSOD were studied by potentiometric and spectroscopic (UV-Vis, CD and EPR) techniques. The results reveal that both ligands have effective metal binding sites, but the tripeptide is a ...

journal_title：Journal of inorganic biochemistry

authors： Bóka B,Myari A,Sóvágó I,Hadjiliadis N

更新日期：2004-01-01 00:00:00

abstract：:Samples of nano-MgO with varying particle sizes were prepared by four different methods using Mg(NO3)2.6H2O, Na2CO3, urea and ammonia as raw materials and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), low temperature N2 adsorption-desorption measurements and FT-IR spectroscopy. Bact...

journal_title：Journal of inorganic biochemistry

authors： Huang L,Li DQ,Lin YJ,Wei M,Evans DG,Duan X

更新日期：2005-05-01 00:00:00

abstract：:Reduced azurin reacts with the resting, oxidized cytochrome c peroxidase of Pseudomonas aeruginosa to yield time courses observed at 420 nm, which consist of the sum of two exponential processes. Each process exhibits a hyperbolic dependence of the observed rate constant on the reduced azurin concentration. The fracti...

journal_title：Journal of inorganic biochemistry

authors： Brittain T,Greenwood C

更新日期：1992-10-01 00:00:00

abstract：:Polythiol binding of metal ions plays crucial role in the proper functioning of cysteine-rich proteins that are responsible for metal homeostasis and defending processes against metal toxicity (including heavy metals detoxification). The coordination properties of cysteine residues involved in specific sequencional pa...

journal_title：Journal of inorganic biochemistry

authors： Krzywoszyńska K,Swiątek-Kozłowska J,Potocki S,Ostrowska M,Kozłowski H

更新日期：2020-03-01 00:00:00

abstract：:Curcumin, a constituent of Curcuma longa L-Zingiberaceae is used in traditional Indian and worldwide medicine and shows anticancer and antioxidant properties. Curcumin has numerous biological and pharmacological activities but due to its hydrophobic nature, the major drawback is poor absorption and rapid elimination, ...

journal_title：Journal of inorganic biochemistry

authors： Shedge AA,Pansare SV,Khairkar SR,Chhatre SY,Chakrabarti S,Nagarkar AA,Pansare AV,Patil VR

更新日期：2020-11-01 00:00:00

abstract：:The reaction between [(eta(6)-p-cymene)Ru(H2O)3]X2 and 4,7-phenanthroline (phen) leads to the formation of the rectangular tetranuclear complexes [(eta(6)-p-cymene)4Ru4(mu-4,7-phen-N4,N7)(2)(mu-OH)4]X4 (X=NO3, 1a; SO3CF3, 1b) which have been structurally characterised by X-ray crystallography. 1H NMR spectroscopic stu...

journal_title：Journal of inorganic biochemistry

authors： Galindo MA,Quirós M,Romero MA,Navarro JA

更新日期：2008-05-01 00:00:00

abstract：:The zinc coordination sphere in prokaryotic zinc finger domain is extremely versatile and influences the stability and the folding property of the domain. Of a particular interest is the fourth zinc coordinating position, which is frequently occupied by two successive histidines, both able to coordinate the metal ion....

journal_title：Journal of inorganic biochemistry

authors： Palmieri M,Russo L,Malgieri G,Esposito S,Baglivo I,Rivellino A,Farina B,de Paola I,Zaccaro L,Milardi D,Isernia C,Pedone PV,Fattorusso R

更新日期：2014-02-01 00:00:00

abstract：:To explore the correlating thermodynamic factors to the structural aspects that account for the stability of the RNA triplex, two functional Ru(II) complexes containing the same ancillary ligands and different intercalative ligands, [Ru(bpy)(2)(mip)](2+) (bpy=2,2'-bipyridine, mip=2'-(3",4"-methylene-dioxyphenyl)imidaz...

journal_title：Journal of inorganic biochemistry

authors： Tan L,Xie L,Sun X,Zeng L,Yang G

更新日期：2013-03-01 00:00:00

abstract：:The interaction of V(IV)O-salts as well as of a few V(IV)O(carrier)n complexes with human serum transferrin (hTF) is studied focusing on the determination of the nature and stoichiometry of the binding of V(IV)O(2+) to hTF, as well as whether the conformation of hTF upon binding to V(IV)O(2+) or to its complexes is ch...

journal_title：Journal of inorganic biochemistry

authors： Mehtab S,Gonçalves G,Roy S,Tomaz AI,Santos-Silva T,Santos MF,Romão MJ,Jakusch T,Kiss T,Pessoa JC

更新日期：2013-04-01 00:00:00

abstract：:Series of dinuclear species [Ru(2)(L)(2)(LH)(2)-mu-S(2)Cl(2)], [Ru(2)(L)(2)(LH)(4)-mu-Se(2)Cl(2)] (L=L(1)H and L(3)H) and [Ru(2)(L(2))(2)(L(2)H)-mu-Se(2)Cl(2)].2H(2)O, where L(1)H, L(2)H and L(3)H represent for 2-mercapto-5-phenyl-1,3,4-oxadiazole, 2-mercapto-benzimidazole and 2-mercapto-benzothiazole, respectively, h...

journal_title：Journal of inorganic biochemistry

authors： Mishra L,Vilaplana R,Singh VK,Yadaw AK,González-Vilchez F

更新日期：2001-09-01 00:00:00

abstract：:Transferrin, the human iron transport protein, binds Ti(IV) even more tightly than it binds Fe(III). However, the fate of titanium bound to transferrin is not well understood. Here we present results which address the fate of titanium once bound to transferrin. We have determined the redox potentials for a series of T...

journal_title：Journal of inorganic biochemistry

authors： Parker Siburt CJ,Lin EM,Brandt SJ,Tinoco AD,Valentine AM,Crumbliss AL

更新日期：2010-09-01 00:00:00

abstract：:Biological studies on [Fe(L)2](NO3).0.5H2O (1), [Fe(L)2][PF6] (2), [Co(L)2](NCS) (3), [Ni(HL)2]Cl2.3H2O (4) and Cu(L)(NO3) (5), where HL=C7H8N4S, pyridine-2-carbaldehyde thiosemicarbazone, have been carried out. The crystal structure of compound 3 has been solved. It consists of discrete monomeric cationic entities co...

journal_title：Journal of inorganic biochemistry

authors： García-Tojal J,García-Orad A,Díaz AA,Serra JL,Urtiaga MK,Arriortua MI,Rojo T

更新日期：2001-04-01 00:00:00

abstract：:A photostable Ru(2,2-biquinoline)2(3-(2-pyridyl)-5-(4-carboxyphenyl)-1,2,4-triazolate) (Ru(biq)2(trzbenzCOOH)) complex that exhibits near-infrared (NIR) emission centred at 786 nm is reported. The parent complex was conjugated via amide coupling to a cell-penetrating peptide sequence octa-arginine (R8), and two signal...

journal_title：Journal of inorganic biochemistry

authors： Cullinane D,Gkika KS,Byrne A,Keyes TE

更新日期：2020-06-01 00:00:00

abstract：:The first reported homogenous rare earth curcumin (HCurc; ((1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione)) complexes with the formula ML3, where M(3+) is Eu(III), Gd(III) or Lu(III), were synthesized and characterized by mass spectrometry, infrared spectroscopy and, in the case of the lutetium co...

journal_title：Journal of inorganic biochemistry

authors： Mawani Y,Orvig C

更新日期：2014-03-01 00:00:00

abstract：:N-pyrimidino benzamide-2-carboxylic acid (NPBCA) and its Cu(II), Ni(II), Co(II), Zn(II), and Mn(II) chelates have been synthesized and characterized by using elemental analyses, molar conductance, molecular weight determination, magnetic moment, infrared, and electronic spectra. Antifungal activity of the synthesized ...

journal_title：Journal of inorganic biochemistry

authors： Nagar R,Mohan G

更新日期：1991-04-01 00:00:00

abstract：:Four binuclear phosphanesilver(I) dithiocarbamates, {cyclohexyl3PAg(S2CNRR')}2 for R = R' = Et (1), CH2CH2 (2), CH2CH2OH (3) and R = Me, R' = CH2CH2OH (4) have been synthesised and characterised by spectroscopy and crystallography, and feature tri-connective, μ2-bridging dithiocarbamate ligands and distorted tetrahedr...

journal_title：Journal of inorganic biochemistry

authors： Tan YJ,Tan YS,Yeo CI,Chew J,Tiekink ERT

更新日期：2019-03-01 00:00:00

abstract：:Lathyrus cicera copper amine oxidase (LCAO) rapidly formed the typical Cu(I)-TPQ semiquinone UV-visible spectrum, identical to that formed by other substrates, upon O(2) exhaustion by turnover with excess tryptamine. A new band at 630 nm formed more slowly, with intensity dependent on aldehyde and H(2)O(2) concentrati...

journal_title：Journal of inorganic biochemistry

authors： Pietrangeli P,Bellelli A,Fattibene P,Mondovì B,Morpurgo L

更新日期：2012-04-01 00:00:00

abstract：:A novel ruthenium(II) compound, trans-cis-cis-[Ru(II)Cl(2)(DMSO)(2)(2-amino-5-methyl-thiazole)(2)], (I), PMRu52 hereafter, that may be obtained from the previously described (cis and trans)-[Ru(II)Cl(2)(DMSO)(4)] complexes, was designed, synthesized and characterised. The single crystal X-ray structure shows a roughly...

journal_title：Journal of inorganic biochemistry

authors： Mura P,Camalli M,Casini A,Gabbiani C,Messori L

更新日期：2010-02-01 00:00:00

abstract：:A comparative study of the Cu2+ effects, binding and reduction, has been performed on rat liver mitochondria. In the first minutes, Cu2+ (less than or equal to 50 micron) is massively bound and reduced to the extent of 70%-80% while a simultaneous activation of respiration takes place. Then the remaining 20% or so of ...

journal_title：Journal of inorganic biochemistry

authors： Leblondel G,Allain P

更新日期：1984-07-01 00:00:00

abstract：:When pulsed cytochrome c oxidase is exposed to carbon monoxide in the absence of oxygen the enzyme is converted quickly to its CO-associated mixed valence state. The half-time for this reaction at 0 degree C is about 4 min. This is about 100 times faster than a similar reaction which begins with the resting form of th...

journal_title：Journal of inorganic biochemistry

authors： Morgan JE,Blair DF,Chan SI

更新日期：1985-03-01 00:00:00

abstract：:Effect of dietary selenium as sodium selenite on in vivo hematological parameters of Sprague-Dawley rats was examined over a 7-month period. Dietary selenium did not alter total hemoglobin, hematocrits, erythrocyte counts, or the osmotic fragility pattern of rat blood. Selenium-excessive (1.0 ppm) rats showed slightly...

journal_title：Journal of inorganic biochemistry

authors： Hu ML,Chung C,Spallholz JE

更新日期：1984-11-01 00:00:00

abstract：:Anticancer activity of the new [Ru(η(5)-C5H5)(PPh3)(Me2bpy)][CF3SO3] (Me2bpy = 4,4'-dimethyl-2,2'-bipyridine) complex was evaluated in vitro against several human cancer cell lines, namely A2780, A2780CisR, HT29, MCF7, MDAMB231 and PC3. Remarkably, the IC50 values, placed in the nanomolar and sub-micromolar range, lar...

journal_title：Journal of inorganic biochemistry

authors： Morais TS,Santos F,Côrte-Real L,Marques F,Robalo MP,Madeira PJ,Garcia MH

更新日期：2013-05-01 00:00:00

abstract：:Marinobactins A-E are a suite of amphiphilic siderophores which have a common peptidic head group that coordinates Fe(III), and a fatty acid which varies in length and saturation. As a result of the amphiphilic properties of these siderophores it is difficult to study siderophore-mediated uptake of iron, because the a...

journal_title：Journal of inorganic biochemistry

authors： Martinez JS,Butler A

更新日期：2007-11-01 00:00:00

abstract：:An in vitro and in vivo study of some copper chelating anti-inflammatory agents for alleviation of inflammation associated with rheumatoid arthritis (RA) has been conducted. Two copper chelating agents, N(1)-(2-aminoethyl)-N(2)-(pyridin-2-ylmethyl)ethane-1,2-diamine ([555-N]) and N-(2-(2-aminoethylamino)ethyl)picolina...

journal_title：Journal of inorganic biochemistry

authors： Zvimba JN,Jackson GE

更新日期：2007-01-01 00:00:00