当前位置： SCI文献检索 > Biomed Research International期刊下所有文献 > The Effect of Omega-3 Docosahexaenoic Acid Supplementation on Gestational Length: Randomized Trial of Supplementation Compared to Nutrition Education for Increasing n-3 Intake from Foods.

The Effect of Omega-3 Docosahexaenoic Acid Supplementation on Gestational Length: Randomized Trial of Supplementation Compared to Nutrition Education for Increasing n-3 Intake from Foods.

Abstract：

OBJECTIVE:DHA supplementation was compared to nutrition education to increase DHA consumption from fish and DHA fortified foods. DESIGN:This two-part intervention included a randomized double-blind placebo controlled DHA supplementation arm and a nutrition education arm designed to increase intake of DHA from dietary sources by 300 mg per day. SETTING:Denver Health Hospitals and Clinics, Denver, Colorado, USA. POPULATION:871 pregnant women aged 18-40 were recruited between 16 and 20 weeks of gestation of whom 564 completed the study and complete delivery data was available in 505 women and infants. METHODS:Subjects received either 300 or 600 mg DHA or olive oil placebo or nutrition education. MAIN OUTCOME VARIABLE:Gestational length. RESULTS:Gestational length was significantly increased by 4.0-4.5 days in women supplemented with 600 mg DHA per day or provided with nutrition education. Each 1% increase in RBC DHA at delivery was associated with a 1.6-day increase in gestational length. No significant effects on birth weight, birth length, or head circumference were demonstrated. The rate of early preterm birth (1.7%) in those supplemented with DHA (combined 300 and 600 mg/day) was significantly lower than in controls. CONCLUSION:Nutrition education or supplementation with DHA can be effective in increasing gestational length.

journal_name

Biomed Res Int

journal_title

BioMed research international

authors

Harris MA,Reece MS,McGregor JA,Wilson JW,Burke SM,Wheeler M,Anderson JE,Auld GW,French JI,Allen KG

doi

10.1155/2015/123078

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

123078

eissn

2314-6133

issn

2314-6141

journal_volume

2015

pub_type

杂志文章,随机对照试验

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