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Epidemiology of HIV-Associated Tuberculosis in Urumqi, China.

Abstract：

:The aim of this work was to understand the epidemiologic characteristics of TB and human immunodeficiency virus (HIV) dual infection cases, thus providing the basis for effective prevention and control measures. On the basis of HIV/TB screening of new and old TB and HIV/acquired immunodeficiency syndrome (AIDS) patients registered in 4 regions of Urumqi, Xinjiang, People's Republic of China, from 2012 to 2014, an analysis was made of the epidemiologic characteristics and risk factors of people suffering from HIV/TB dual infection. A total of 2,645 TB patients were tested for HIV antibodies, of whom 128 tested positive, showing a detection rate of 4.8%; TB patients ≥35 years old had 0.26 times (95% confidence interval [CI], 0.18-0.40) the risk of HIV infection than those 18-35 years old, and pulmonary and extrapulmonary TB patients with positive smear had, respectively, 0.43 times (95% CI, 0.28-0.66) and 1.79 times (95% CI, 1.09-2.94) the risk of HIV infection than those with negative smear. And 1,195 HIV/AIDS patients were screened for TB, of whom 91 were positive, showing an infection rate of 7.6%; male HIV/AIDS patients had 12.2 times (95% CI, 6.4-23.1) the risk of TB infection than female patients, and HIV/AIDS patients with CD4 cells ≤200/μL had 20.4 times (95% CI, 11.8-35.3) the risk of TB infection than those with CD4 cells >200/μL. TB and HIV/AIDS patients in Urumqi from 2012 to 2014 suffered from high HIV and TB infection rates, so relevant measures should be taken to intervene, especially for TB patients ≥35 years old, those with positive smear, extrapulmonary TB patients, male HIV/AIDS patients, and those with CD4 cells ≤200/μL.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Li WG,Zhao L,Zhao H

doi

10.1016/j.transproceed.2015.09.017

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

2456-9

issue

8

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(15)00869-6

journal_volume

47

pub_type

杂志文章

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