Three patterns of voluntary consent in the case of adult-to-adult living related liver transplantation in Japan.


:To elucidate the psychosocial aspects of the donors' decisions to engage in adult-to-adult living related liver transplantation, we interviewed a total of five institutional ethics committee members who had experience with reassessing informed consent prior to surgery. Qualitative analysis revealed several nuances of voluntary consent consisting of three patterns: "unconditional consent" is consent from the bottom of one's heart to save a family member's life; "pressured consent" describes a donor who feels implicit pressure to donate despite fear; and "ulterior-motivated consent" defines a donor who has a hidden motive. This study diverges from previous work in that it employs a qualitative approach to deconstructing the psychosocial intricacies of the informed consent process in adult-to-adult LRLT. This initial study raises several questions on the meaning of voluntary informed consent in adult-to-adult living related liver transplantation.


Transplant Proc


Fujita M,Slingsby BT,Akabayashi A




Has Abstract


2004-06-01 00:00:00














  • Transplantation of cryopreserved pancreatic islets into the portal vein.

    abstract::Pancreatic islet cells of rats obtained by the collagenase digestion method were preserved from 7 to 10 days at -80 degrees C in a deep freezer or at -196 degrees C in liquid nitrogen with Dulbecco modified Eagle's medium, supplemented with 10% or 20% DMSO (dimethyl sulfoxide); thawing was performed in a 37 degree C w...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Nakagawara G,Kojima Y,Mizukami T,Ono S,Miyazaki I

    更新日期:1981-06-01 00:00:00

  • Perioperative considerations in HIV-infected liver transplanted patients.

    abstract:UNLABELLED:The introduction of highly active antiretroviral therapy (HAART) has improved survival in HIV patients, allowing them to undergo liver transplantation (OLT) in cases of end-stage liver disease. HIV patients show a higher incidence of pulmonary hypertension. The aim of this study was to evaluate pulmonary and...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Costa MG,Pompei L,Chiarandini P,Lugano M,Baccarani U,Tavio M,Della Rocca G

    更新日期:2009-05-01 00:00:00

  • Ten years' evaluation of diet, anthropometry, and physical exercise adherence after islet allotransplantation.

    abstract::Allogeneic islet transplantation (IT) provokes changes in metabolic responses and nutritional behaviors. The durability of these changes needs to be described as well as their impact on the recipients' lifestyle. The goal of this study was to investigate how islet transplantation influenced diet, exercise habits, and ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Delmonte V,Peixoto EM,Poggioli R,Enfield G,Luzi L,Ricordi C,Alejandro R

    更新日期:2013-06-01 00:00:00

  • Learning and new discovery with cyclosporine in the Cambridge-King's Programme: a personal view.

    abstract::Immunosuppressive regimens in the early precyclosporine days of liver transplantation for the Cambridge-King's Programme from 1968 until the early 1980s were inadequate in the control of rejection. The consequent use of high-dose steroids led to many infections, which seriously affected outcome. Nevertheless, occasion...

    journal_title:Transplantation proceedings

    pub_type: 历史文章,杂志文章


    authors: Williams R

    更新日期:2004-03-01 00:00:00

  • Exchange of organs and patients with foreign nations during the first 15 months of activity of the Italian gate to Europe.

    abstract::The Italian Gate to Europe (IGE) was established in April 2005 to supply a single national coordinating center for the exchange of organs and patients with the rest of Europe. When an organ is offered from Italy, the IGE ascribes it to the first foreign organization that accepts it on a first-come, first-served basis....

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Pretagostini R,Peritore D,Di Ciaccio P,Stabile D,Fiaschetti P,Ricci A,Venettoni S,Nanni Costa A

    更新日期:2007-07-01 00:00:00

  • Specific tolerance to canine renal allografts following treatment with fractionated bone marrow and antilymphocyte serum.

    abstract::These results suggest (1) that ALS + BM fractions can be used to promote tolerance in long-term graft survivors; (2) that the presence of apparent BM cells of donor origin in the allograft in normally functioning kidneys may be related to the mechanism of allograft prolongation, and (3) that some promise of possible s...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Hartner WC,De Fazio SR,Markees TG,Maki T,Monaco AP,Gozzo JJ

    更新日期:1987-02-01 00:00:00

  • Xeno-kidney transplantation: from idea to reality.

    abstract::Although kidney transplantation is a widely used therapy for chronic renal failure, not all patients can be transplanted due to the limited numbers of organ donations. A possible solution could be xenogenic kidney transplantation. Herein we have described the present state, problems and possible solutions using xenogr...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审


    authors: Ramackers W,Klose J,Winkler M

    更新日期:2012-07-01 00:00:00

  • A pilot study on the safety and efficacy of generic mycophenolate agent as conversion maintenance therapy in stable liver transplant recipients.

    abstract:PURPOSE:The patent covering mycophenolate mofetil (MMF) in Korea has expired and, thus, several generic MMF agents are now commercially available. The supply of Cellcept (Roche Korea) was interrupted at the end of 2011, so it was inevitable that a generic MMF would be used instead. During this period, we performed a pr...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Namgoong JM,Hwang S,Ahn CS,Kim KH,Moon DB,Ha TY,Song GW,Jung DH,Park GC,Park HW,Park CS,Park YH,Kang SH,Jung BH,Lee SG

    更新日期:2013-10-01 00:00:00

  • Knowledge and Willingness to Donate Kidneys for Transplantation in Ghana: A Cross-Sectional Survey.

    abstract:BACKGROUND:The main treatment modalities for chronic kidney disease (CKD) are dialysis and kidney transplantation. While kidney transplantation provides better survival and quality of life outcomes, it is a new treatment option in Ghana. Finding kidney donors for transplant may be a major challenge due to varied views ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Boima V,Ganu V,Yorke E,Dey D,Amissah-Arthur MB,Agyabeng K,Yawson A,Lartey M,Mate-Kole CC

    更新日期:2020-12-01 00:00:00

  • Investigation of the biomechanical integrity of decellularized rat abdominal aorta.

    abstract:OBJECTIVES:The loss or damage of an organ or tissue is one of the most common and devastating problems in healthcare today. Tissue engineering applies the principles of engineering and biology toward the development of functional biological replacements that are able to maintain, improve, or restore the function of pat...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Katsimpoulas M,Morticelli L,Michalopoulos E,Gontika I,Stavropoulos-Giokas C,Kostakis A,Haverich A,Korossis S

    更新日期:2015-05-01 00:00:00

  • Techniques of vascular control in laparoscopic donor nephrectomy.

    abstract:OBJECTIVES:Laparoscopic donor nephrectomy has become the method of choice for removal of living donor kidneys. The ENDO GIA stapler is commonly used for division of the renal vessels, but it can lead to some loss of graft vascular length. Besides, stapler malfunction can occur. In this study, we report our experience u...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Liu KL,Chiang YJ,Wang HH,Chu SH

    更新日期:2008-09-01 00:00:00

  • Rapid conversion to sirolimus for chronic progressive deterioration of the renal function in kidney allograft recipients.

    abstract::The aim of this study was to evaluate the safety of conversion to sirolimus (SRL) immunosuppression among 19 renal transplant recipients (KTX) with progressive chronic renal allograft dysfunction (CRAD). Conversion to SRL was performed with concomitant sharp withdrawal of the calcineurin inhibitor (CI). SRL was added ...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章


    authors: Citterlo F,Scatà MC,Violi P,Romagnoli J,Pozzetto U,Nanni G,Castagneto M

    更新日期:2003-06-01 00:00:00

  • No harmful effect of mycophenolate mofetil on liver regeneration: an experimental study.

    abstract:AIM:The aim of this experimental study was to examine the effects of mycophenolate mofetil (MMF) on liver regeneration in a partial hepatectomy model. METHODS:Rats were divided into 3 groups immediately following partial liver resection: saline, controls intraperitoneally (MMF; Group 1); MMF (15 mg/kg/d; Group II), an...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Demiray M,Kucuk HF,Yildirim M,Barisik NO

    更新日期:2012-07-01 00:00:00

  • Donor-Derived Cell-Free DNA Is a Novel Universal Biomarker for Allograft Rejection in Solid Organ Transplantation.

    abstract:BACKGROUND:In solid organ transplantation, sensitive real-time biomarkers to assess the graft health are desirable to enable early intervention, for example, to avoid full-blown rejections. During rejection, high amounts of graft-derived cell-free DNA (GcfDNA) are shed into the blood stream. The quantification of this ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Beck J,Oellerich M,Schulz U,Schauerte V,Reinhard L,Fuchs U,Knabbe C,Zittermann A,Olbricht C,Gummert JF,Shipkova M,Birschmann I,Wieland E,Schütz E

    更新日期:2015-10-01 00:00:00

  • Renal Cell Carcinoma in Kidney Transplant Candidates.

    abstract:BACKGROUND:An increased incidence of renal cell carcinoma (RCC) has been observed in patients with end-stage renal disease. However, the incidence of this pathological condition has not been studied adequately in kidney transplant candidates. The aim of this study was to examine the incidence of RCC and the clinical, i...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Zorbas KA,Karhadkar SS,Lau KN,Di Carlo A

    更新日期:2017-01-01 00:00:00

  • Age, gender, race, and associations with kidney failure following living kidney donation.

    abstract:INTRODUCTION:Our previous reports suggested that African Americans (AA) are more likely to develop end-stage renal disease (ESRD) following kidney donation when compared with white counterparts. We sought information on age, gender, and race of kidney donors to determine which groups were over-represented on the kidney...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Gibney EM,Parikh CR,Garg AX

    更新日期:2008-06-01 00:00:00

  • Monitoring FK 506 concentrations in plasma and whole blood.

    abstract::The FCL provides support for clinical trials of FK 506 in liver transplantation by monitoring drug concentrations in plasma and whole blood. The sensitive EIA method of Tamura et al was adapted for routine use. Extraction of drug from 300 microL plasma or 20 microL whole blood samples was carried out using MeCl. An al...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Jusko WJ,D'Ambrosio R

    更新日期:1991-12-01 00:00:00

  • Results of a two-center study comparing hepatic fibrosis progression in HCV-positive liver transplant patients receiving cyclosporine or tacrolimus.

    abstract::A 2-center retrospective analysis was performed in 60 patients undergoing liver transplantation for hepatitis C virus (HCV)-related disease (cyclosporine in 20, tacrolimus in 40). Mean (±SEM) follow-up was 23.6 ± 22.5 and 22.3 ± 13.7 months in patients receiving cyclosporine or tacrolimus, respectively. Clinically ind...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,多中心研究


    authors: van der Laan LJ,Hudson M,McPherson S,Zondervan PE,Thomas RC,Kwekkeboom J,Lindsay AS,Burt AD,Kazemier G,Tilanus HW,Bassendine MF,Metselaar HJ

    更新日期:2010-12-01 00:00:00

  • Prolongation of islet allograft survival by coexpression of CTLA4Ig and CD40LIg in mice.

    abstract:BACKGROUND:B7/CD28 and CD40/CD40L have been well established as important costimulatory pathways. Cytotoxic T lymphocyte-associated antigen-4 (CTLA4) delivers negative signals to antigen-presenting cells to down-regulate proinflammatory responses and competitively inhibits the binding of B7 and CD28. Signals from the C...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Li ZL,Xue WJ,Tian PX,Ding XM,Tian XH,Feng XS,Hou J

    更新日期:2007-12-01 00:00:00

  • Effect of calcineurin inhibitors on low-density lipoprotein oxidation.

    abstract:INTRODUCTION:Low-density lipoprotein (LDL) oxidation is considered a key factor in the biological processes that trigger and accelerate atherosclerosis. Reported data suggest that tacrolimus improves the lipid profile in renal transplant recipients. OBJECTIVE:The objective of this study was to analyze the effect of co...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章


    authors: Cofan F,Cofan M,Campos B,Guerra R,Campistol JM,Oppenheimer F

    更新日期:2005-11-01 00:00:00

  • Donor MHC class I peptides in conjunction with self-epitopes induce donor-specific tolerance in a dose-dependent manner but unable to abrogate chronic rejection.

    abstract::Understanding specific tolerance mechanisms is a primary goal of transplantation science. We have previously shown that hosts treated with MHC class I protein have donor sequences in the alpha1-helix of the alpha1 domain on a background of self-epitopes, resulting in the development of donor-specific tolerance. Howeve...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Semiletova NV,Shen XD,Feldman DM,Busuttil RW,Kupiec-Weglinski JW,Ghobrial RM

    更新日期:2005-05-01 00:00:00

  • Long-term Results of Living Donors in Simultaneous Kidney and Liver Transplantations.

    abstract:INTRODUCTION:Because of the shortage of organs available for transplantation, living related sequential transplantation with the use of liver and a kidney from the same donor has emerged as a reasonable therapeutic alternative. However, there is insufficient literature about the complications that living donors experie...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Unek T,Egeli T,Özbilgin M,Çelik A,Atilla K,Ağalar C,Arslan NÇ,Karademir S,Bora S,Gülay H,Derici ZS,Astarcıoğlu I

    更新日期:2017-04-01 00:00:00

  • Hemophagocytic Lymphohistiocytosis in Renal Transplant Recipients: A 2-Case Report.

    abstract:BACKGROUND:Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome characterized by an excessive immune activation. HLH can be triggered by a variety of events that disrupt immune homeostasis, such as infections and immunosuppression. HLH presents with heterogeneous clinical symptoms and laboratory find...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Mascia G,Argiolas D,Carta E,Ibba S,Piredda GB

    更新日期:2020-06-01 00:00:00

  • Living related liver transplantation. Why this option has been discarded in a pediatric liver transplant program in Chile.

    abstract::Living related living transplantation (LRLT) has opened new possibilities for planning transplantation in better conditions for children with emergency situations and chronic liver diseases. Since we began the LRLT program in 1999, we have performed 57 pediatric liver transplants, 17 (29.8%) using living related donor...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Uribe M,Buckel E,Ferrario M,Godoy J,González G,Ceresa S,Hunter B,Cavallieri S,Berwart F,Blanco A,Smok G,Calabrán L,Herzog C,Santander MT

    更新日期:2005-10-01 00:00:00

  • São Paulo lung transplantation waiting list: patient characteristics and predictors of death.

    abstract:INTRODUCTION:Nowadays, lung transplantation (LTx) allocation in Brazil is based mainly on waiting time. There is a need to evaluate the equity of the current lung allocation system. OBJECTIVES:We sought to (1) determine the characteristics of registered patients on the waiting list and (2) identify predictors of death...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Costa da Silva F Jr,Afonso JE Jr,Pêgo-Fernandes PM,Caramori ML,Jatene FB

    更新日期:2009-04-01 00:00:00

  • Old male living renal transplant recipients more likely to be at risk for colorectal cancer.

    abstract:BACKGROUND:The development of posttransplant malignancy is a well-recognized complication of kidney transplantation due to immunosuppressive therapy. The literature on colorectal malignancy in living renal transplant recipients are limited; most of the data have been collected from deceased donor cases. As living kidne...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,多中心研究


    authors: Rostami Z,Einollahi B,Lessan-Pezeshki M,Nourbala MH,Nemati E,Pourfarziani V,Shahbazian H,Khosravi M,Jalalzadeh M

    更新日期:2011-03-01 00:00:00

  • Effect of Different Sensitization Events on HLA Alloimmunization in Kidney Transplantation Candidates.

    abstract:BACKGROUND:HLA alloimmunization is caused by sensitization events (SEs), such as transfusion, pregnancy, or previous organ transplantation, and the effects of particular SEs have not been thoroughly studied. Our aim was to evaluate how each SE affected HLA alloimmunization by considering Luminex assays. METHODS:Sera f...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lopes D,Barra T,Malheiro J,Tafulo S,Martins L,Almeida M,Pedroso S,Dias L,Castro Henriques A,Cabrita A

    更新日期:2015-05-01 00:00:00

  • Factors affecting graft survival after living donor liver transplantation.

    abstract::Living donor liver transplantation (LDLT) has been considered as an alternative option to resolve the shortage of cadaveric donor organs, despite the ethical aspects of the donor procedure. The objective of this study was to analyze the risk factors affecting graft survival in LDLT. From June 1996 to December 2002, 14...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lee DS,Gil WH,Lee HH,Lee KW,Lee SK,Kim SJ,Choi SH,Heo JS,Hyon WS,Kim GS,Paik SW,Koh KC,Joh JW

    更新日期:2004-10-01 00:00:00

  • Optimal cyclosporine plasma levels decline with time of therapy.

    abstract::To avoid nephrotoxicity and hepatotoxicity the CsA-PL should be kept at less than 500 ng/mL during the first month after transplantation and less than 200 ng/mL after four months. After ten months most patients in this study had a CsA-PL of less than 150 ng/mL and many had levels of less than 50 ng/mL with an apparent...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Klintmalm G,Säwe J,von Bahr C,Ringdén O,Lundgren G,Wilczek H,Tydén G,Groth CG

    更新日期:1984-10-01 00:00:00

  • A patient with hepatic artery thrombosis after living-donor liver transplantation survived the great East Japan earthquake 3 days after reoperation: a case report.

    abstract:BACKGROUND:On March 11, 2011, our hospital was severely damaged by the Great East Japan Earthquake. We report the rare case of a 5-month-old patient with hepatic artery thrombosis (HAT) after living donor liver transplantation (LDLT), who survived the earthquake that occurred 3 days after the reoperation; we were able ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Miyagi S,Kawagishi N,Satoh K,Sekiguchi S,Ohuchi N,Satomi S

    更新日期:2013-06-01 00:00:00