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How reconstructive transplantation is different from organ transplantation--and how it is not.

Abstract：

:An evolution of understanding and knowledge gained over more than 100 years in the field of solid organ transplantation (SOT) led to the first successful clinical cases of composite tissue allotransplantation. In many ways reconstructive transplantation (RT) is similar to SOT; however, certain characteristics make this novel type of transplantation unique, interesting, and challenging for both clinicians/scientists and patients. Currently, RT is a rapidly advancing multidisciplinary clinical reality. With over 100 clinical cases performed over the past 12 years, and encouraging early to midterm results, the relevance of RT for treatment of congenital and acquired tissue defects unsalvageable by conventional reconstruction is significant and holds great potential for the future. We herein report the extraordinary progress in this field with particular discussion of a comparative analysis of the similarities and differences regarding indications, end point, failure, patient and graft survival, and side effects between SOT and RT.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Hautz T,Brandacher G,Engelhardt TO,Pierer G,Lee WP,Pratschke J,Schneeberger S

doi

10.1016/j.transproceed.2011.08.044

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

3504-11

issue

9

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(11)01088-8

journal_volume

43

pub_type

杂志文章,评审

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