Abstract:
:The ability of the somatosensory cortex in differentiating various tactile sensations is very important for a person to perceive the surrounding environment. In this study, we utilize a lab-made multi-channel functional near-infrared spectroscopy (fNIRS) to discriminate the hemodynamic responses (HRs) of four different tactile stimulations (handshake, ball grasp, poking, and cold temperature) applied to the right hand of eight healthy male subjects. The activated brain areas per stimulation are identified with the t-values between the measured data and the desired hemodynamic response function. Linear discriminant analysis is utilized to classify the acquired data into four classes based on three features (mean, peak value, and skewness) of the associated oxy-hemoglobin (HbO) signals. The HRs evoked by the handshake and poking stimulations showed higher peak values in HbO than the ball grasp and cold temperature stimulations. For comparison purposes, additional two-class classifications of poking vs. temperature and handshake vs. ball grasp were performed. The attained classification accuracies were higher than the corresponding chance levels. Our results indicate that fNIRS can be used as an objective measure discriminating different tactile stimulations from the somatosensory cortex of human brain.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Hong KS,Bhutta MR,Liu X,Shin YIdoi
10.1016/j.bbr.2017.06.034subject
Has Abstractpub_date
2017-08-30 00:00:00pages
225-234eissn
0166-4328issn
1872-7549pii
S0166-4328(17)30157-2journal_volume
333pub_type
杂志文章abstract::We investigated the neurobiological bases of variation in response to predator stress (PS). Sixteen days after treatment (PS or handling), rats were grouped according to anxiety in the elevated plus maze (EPM). Acoustic startle was also measured. We examined the structure of dendritic trees of basolateral amygdala (BL...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.09.009
更新日期:2012-01-01 00:00:00
abstract::Self-injurious behaviour (SIB) is a debilitating characteristic that is highly prevalent in autism and other neurodevelopmental disorders. Pathological anxiety is also common, and there are reports of comorbid anxiety and self-injury in some children. We have investigated potential interactions between anxiety and sel...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.05.041
更新日期:2016-09-15 00:00:00
abstract::Rats with lesions in either the fornix or the thalamic nucleus medialis dorsalis were unimpaired on the acquisition of two object discrimination tasks. The same animals were then tested on a concurrent learning task in which various object discriminations were presented at different rates during the same session. This...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(94)90028-0
更新日期:1994-06-30 00:00:00
abstract::Skilled motor actions are mediated by neural mechanisms that incorporate sensory feedback for driving or suppressing movement with remarkable temporal precision. The predictive coding model proposes that the brain performs this function by establishing an internal representation of timing to accelerate movement respon...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.03.028
更新日期:2018-07-16 00:00:00
abstract::Corticotrophin releasing factor (CRF) modulates stress/anxiety-related responses. Previous studies showed that exposure to acute restraint and unpredictable chronic mild stress (UCMS) facilitates elevated T-maze (ETM) avoidance responses, an anxiogenic-like effect. This study verified the role of CRF in the modulation...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.09.029
更新日期:2018-01-30 00:00:00
abstract::Spatial navigation is achieved through both egocentric (body-centered) and allocentric (externally-centered) strategies but decline with age, especially allocentric strategies. A better understanding of the neurobiological mechanisms underlying these strategies would allow the development of new treatments to mitigate...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.12.006
更新日期:2017-03-01 00:00:00
abstract::Previous studies have suggested that ethanol exposure during brain development affects responses to fear and anxiety after maturity. To clarify in detail the impaired behavior related to fear and anxiety seen in rat offspring prenatally exposed to ethanol, their behaviors were observed using an elevated T-maze (ETM) t...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2012.07.001
更新日期:2012-10-01 00:00:00
abstract::The present study was outlined in order to provide additional behavioral validation to the elevated T-maze as a model of anxiety and memory. In this model, rats acquire an inhibitory avoidance response after successive exposures, and memory can be estimated by retesting later. Two experiments were carried out with rat...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(98)00140-5
更新日期:1999-05-01 00:00:00
abstract::Injections of carbachol (CCh) through a chronic cannula into the midbrain periaqueductal grey region (PAG) of the cat induced an emotional-defensive response (EDR) which was evaluated by duration and number of growls in a 30-min experimental session. That response was examined before and after injection of kainic acid...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(89)80002-6
更新日期:1989-10-01 00:00:00
abstract::The present study tested eight boys with attention-deficit/hyperactivity disorder (ADHD) and 12 normal boys (comparison group), aged 7-12 years, to investigate the hypothesis that ADHD is associated with a steeper and shorter delay-of-reinforcement gradient than is normal. A two-component schedule of reinforcement was...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::Adolescents display high levels of interactions with peers relative to other age groups, with these interactions further enhanced by ethanol under some circumstances. Understanding of the neural mechanisms underlying these high levels of social interactions is important given that alcohol use is initiated during adole...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.04.050
更新日期:2013-08-01 00:00:00
abstract::It has been shown that a variety of stressful procedures, such as immobilization and footshock, can induce a significant degree of analgesia in mice. In addition, it has been shown that for some, but not all, stressful treatments, the analgesic effect is mediated via endogenous opioids. This report describes the effec...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(83)90041-4
更新日期:1983-12-01 00:00:00
abstract::Previous experiments demonstrate a normal decline in unconditioned responding in rats with perirhinal cortex lesions but attenuated performance on spontaneous object recognition (SOR), a finding supporting the assertion that distinct systems support these phenomena. This finding informs on the nature of these two fund...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2012.01.033
更新日期:2012-04-15 00:00:00
abstract::The immediate early genes (IEGs) have been suggested to be implicated in mechanisms of addiction, as well as in learning and memory processes. fosB, which belongs to IEG, has been reported to have pleiotropic impact on response to psychoactive drugs, as well as motivational and stress-related behaviours. In the presen...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2008.02.040
更新日期:2008-07-19 00:00:00
abstract::To assess the role of endogenous peptides involved in stress responsivity in the development of diet-induced obesity (DIO), selectively bred DIO and diet-resistant (DR) male were weaned onto a low fat (4.5%) chow diet at 3 weeks of age and then fed either chow or a 31% fat by energy content (high energy (HE)) diet for...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2004.03.019
更新日期:2004-10-05 00:00:00
abstract::Nicotine withdrawal is associated with numerous symptoms including impaired hippocampus-dependent learning. Theories of nicotine withdrawal suggest that nicotinic acetylcholine receptors (nAChRs) are hypersensitive during withdrawal, which suggests enhanced sensitivity to nicotine challenge. Research indicates that pr...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.04.053
更新日期:2013-08-01 00:00:00
abstract::Pavlovian conditioning of drug effects is generally acknowledged to be a critical factor in the development and persistence of drug addiction. In drug conditioning the focus has essentially been on one type of Pavlovian conditioning, namely, delay conditioning in which the CS and drug UCS overlap and are temporally co...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/j.bbr.2014.08.053
更新日期:2014-12-15 00:00:00
abstract::The effects of intracerebroventricular (i.c.v.) administration of ultra low doses (ULDs) of histamine, clobenpropit and pyrilamine are studied on morphine state-dependent (STD) memory in mice. Although pre-test administration of different doses of histamine and clobenpropit showed no effect on impairment of memory ind...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2005.07.014
更新日期:2006-01-06 00:00:00
abstract::The present study investigated the involvement of nitric oxide (NO) in phencyclidine (PCP)-induced place aversion and preference in the place conditioning paradigm. PCP-induced place aversion in naive mice was dose-dependently attenuated by administration of N(G)-nitro-L-arginine methyl ester (L-NAME), a NO synthase (...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(00)00274-6
更新日期:2000-12-05 00:00:00
abstract::The study concerns rats conceived, born and raised in a hypergravity environment (HG: 2 g) for 3 months using a centrifuge. They were then exposed to terrestrial gravity (1 g) and submitted to behavioural tests investigating their spontaneous locomotor activity (open-field), their posture (support surface), and their ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00085-2
更新日期:2003-02-17 00:00:00
abstract::Narp knockout (KO) mice demonstrate cognitive inflexibility and addictive behavior, which are associated with abnormal reactivity to a novel stimulus. To assess reactivity to novelty, we tested Narp KO and wild-type (WT) mice on a neophobia procedure. Both Narp KO and WT mice showed a similar decrease in consumption u...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.10.001
更新日期:2013-11-15 00:00:00
abstract::It is generally acknowledged that psychosis occurs with increased frequency within epileptic populations. There are several possible explanations for this over-representation: (1) psychosis may develop as a result of anti-epileptic drug or surgical treatment, or as a result of the psychosocial effects of living with e...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/0166-4328(96)00157-x
更新日期:1996-02-01 00:00:00
abstract::To study the role of hippocampal muscarinic receptors in spatial learning, various doses of scopolamine were injected bilaterally into the CA1 region of the dorsal hippocampus of rats trained in a two-platform spatial discrimination task. Scopolamine administered 10 min before each training session at doses ranging fr...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(97)80988-6
更新日期:1997-01-01 00:00:00
abstract::Effects of aspiration lesions of the cerebral cortex on the behavioral effects of intraventricular substantia nigra grafts were investigated. Apomorphine-induced rotational behavior consequent to unilateral lesions of the substantia nigra was used as a behavioral measure. Substantia nigra grafts reduced rotational beh...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(89)80060-9
更新日期:1989-04-01 00:00:00
abstract::The behavioural effects of hippocampal lesions have been extensively documented in rats. However, paradigms developed for rats cannot be assumed to transfer straightforwardly to mice; the behaviour of the two species differs in many respects. Mice are currently the species of choice for targeted genetic manipulations....
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(01)00401-6
更新日期:2002-05-14 00:00:00
abstract::The T-type calcium channel blocker, Z944, has been used as a pharmacological tool to assess T-type calcium channel function and examined for use as an anti-epileptic. As Z944 affects fear learning and memory in a rodent model of absence epilepsy, it is important to determine the effect of Z944 on learning and memory i...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2020.112747
更新日期:2020-09-01 00:00:00
abstract::Repetitive exposure to opioids elicits sensitization to its psychomotor stimulating effect and environmental stimuli contribute to this effect. This study first developed a procedure that simultaneously measures conditioned hyperactivity and locomotor sensitization, and then investigated the effects of physostigmine o...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2009.09.016
更新日期:2010-01-20 00:00:00
abstract::Receptors for glucocorticoid (GR) and corticotropin-releasing hormone (CRH) are largely found in brain sensorimotor structures, particularly in cerebellum, underlining a potential role of stress hormones in the regulation of motor function. Since CRH is involved in neuroplasticity, known for its trophic effect on syna...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.02.035
更新日期:2017-05-30 00:00:00
abstract::Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a clinically and progressive loss of cognitive function, neuropsychiatric and behavioral disorders. Some studies showed that chrysin has antioxidant and anti-inflammatory properties. However, your bioavailability is relatively low. Therefore, th...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2020.112696
更新日期:2020-07-15 00:00:00
abstract::Protein phosphorylation is a well-known and well-documented mechanism in memory processes. Although a large series of protein kinases involved in memory processes have been reported, information on phosphoproteins is limited. It was therefore the aim of the study to determine a partial and differential phosphoproteome...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.01.047
更新日期:2014-05-01 00:00:00