Abstract：
:Rats with lesions in either the fornix or the thalamic nucleus medialis dorsalis were unimpaired on the acquisition of two object discrimination tasks. The same animals were then tested on a concurrent learning task in which various object discriminations were presented at different rates during the same session. This arrangement was primarily designed to minimise any response bias effects. Animals were able to acquire the various concurrent tasks, even when only one trial per day was given for a particular discrimination. It was found that fornix lesions had little or no effect and only produced a mild impairment when the rate of stimulus presentation resembled that used in typical concurrent tasks. Lesions of medialis dorsalis produced a more general, but again mild, deficit. In a final task, the animals were trained to discriminate between two stimuli composed of common elements arranged in different spatial combinations. Fornix lesions impaired acquisition of this spatial configural discrimination, while lesions of medialis dorsalis had a variable effect. The results indicate that fornix lesions can spare concurrent discrimination learning, and that any deficits may be related to interference effects associated with common elements in the stimuli. Lesions in medialis dorsalis appear to affect the initial learning of reward-based performance rules.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Hunt PR,Neave N,Shaw C,Aggleton JPdoi
10.1016/0166-4328(94)90028-0subject
Has Abstractpub_date
1994-06-30 00:00:00pages
195-205issue
2eissn
0166-4328issn
1872-7549pii
0166-4328(94)90028-0journal_volume
62pub_type
杂志文章abstract：:Defensive behaviors comprise a set of flexible and adaptive responses to threatening situations and stimuli. In semi-natural situations affording a wide variety of responses, defensive behaviors change over time in response to information about the presence of danger, acquired through risk assessment activities. Two t...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/0166-4328(93)90100-5
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章
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journal_title：Behavioural brain research
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更新日期：2009-08-12 00:00:00
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journal_title：Behavioural brain research
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更新日期：2007-07-19 00:00:00
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章,评审
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更新日期：2010-12-25 00:00:00
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更新日期：2021-01-25 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2018.03.040
更新日期：2018-08-01 00:00:00
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journal_title：Behavioural brain research
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doi：10.1016/0166-4328(83)90041-4
更新日期：1983-12-01 00:00:00
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journal_title：Behavioural brain research
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更新日期：1989-11-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
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更新日期：2014-03-15 00:00:00
abstract：PURPOSE:To explore the effect of vagal nerve stimulation (VNS) on spontaneous brain activity in patients with drug-resistant epilepsy (DRE). METHODS:15 patients and eight healthy controls (HC) were enrolled and scanned by resting-state functional MRI to investigate changes in the fractional amplitude of low-frequency ...
journal_title：Behavioural brain research
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：1984-04-01 00:00:00
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journal_title：Behavioural brain research
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