Abstract：
:Previous experiments demonstrate a normal decline in unconditioned responding in rats with perirhinal cortex lesions but attenuated performance on spontaneous object recognition (SOR), a finding supporting the assertion that distinct systems support these phenomena. This finding informs on the nature of these two fundamental forms of learning and may be taken as support for certain contemporary theories of memory. However, we cannot quantify the relative contributions of genuine habituation and alternative, trivial sources in response decline from effector fatigue and sensory adaptation in these demonstrations. An important implication of this problem is that previous reports may have missed perirhinal-dependent habituation. We report perirhinal cortex lesions to be without effect in rats' habituation of suppression to lights when any influence of effector fatigue and sensory adaptation is eliminated. Theoretical implications of this finding are discussed.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Jones PM,Whitt EJ,Robinson Jdoi
10.1016/j.bbr.2012.01.033subject
Has Abstractpub_date
2012-04-15 00:00:00pages
365-71issue
2eissn
0166-4328issn
1872-7549pii
S0166-4328(12)00056-3journal_volume
229pub_type
杂志文章abstract：:It has long been postulated that exogenous cannabinoids have a profound effect on human cognitive functioning. These cannabinoid effects are thought to depend, at least in parts, on alterations of phase-locking of local field potential neuronal firing. The latter can be measured as activity in the theta frequency band...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.08.003
更新日期：2014-11-01 00:00:00
abstract：:After ablation of the motor cortex contralateral to the preferred limb, rats were forced to use this limb in grasping food out of a horizontal tube by restraining the non-preferred foreleg with a bracelet. In a right-handed rat the motor behaviour is less impaired and the recovery is better after a left hemisphere les...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(93)90032-l
更新日期：1993-09-30 00:00:00
abstract：:Evidence for structural modifications in the brain following environmental changes have been provided during the last decades. The most pronounced alterations following environmental manipulations have been found in the visual cortex. These plastic changes are supposed to reflect reorganization of neuronal connections...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(97)00142-3
更新日期：1998-06-01 00:00:00
abstract：:Chronic administration of a choline-deficient diet for 20 days caused no modification in ACh levels in the cortex, hippocampus and olfactory system of the rat and an increase in the density (Bmax) of the muscarinic receptors in the hippocampus. The choline-deficient diet caused no modification in noradrenaline levels ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(96)00143-x
更新日期：1997-03-01 00:00:00
abstract：:Exposure to early stressful adverse life events such as maternal separation severely impacts the development of the nervous system. Using immunohistochemistry, quantitative PCR and Western blot approaches, we found that alpha6 subunit-containing GABAA receptors (Gabra6-containing GABAA Rs) were expressed on hippocampa...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.07.002
更新日期：2016-10-15 00:00:00
abstract：RATIONALE:Addiction is characterized by inflexible drug consumption: unpleasant consequences are accepted. Rat studies with several drugs proved that long-term voluntary intake induced abstinence-outlasting excessive and inflexible consumption. OBJECTIVE:Establishing a long-term model of oral self-administration of ni...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2010.10.011
更新日期：2011-03-01 00:00:00
abstract：:The human oculomotor system becomes active long before birth. At about 16 weeks (post-menstrual age) the first slow changes of eye position can be observed with the aid of real time ultrasonography. At 18-20 weeks more rapid eye movements are detectable. There is a gradual decline in the percentage of time spent in ra...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(83)90157-2
更新日期：1983-10-01 00:00:00
abstract：:In a short-distance homing task, golden hamsters derive the homing direction both from visual extra-maze cues and from the integration of the outward journey. The relative importance of visual configurations in the control of homing was assessed by presenting these cues in conflict with path integration. The hamsters ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(90)90175-e
更新日期：1990-05-28 00:00:00
abstract：:It has been observed that men and women show performance differences in the Iowa Gambling Task (IGT), a task of decision-making in which subjects through exploration learn to differentiate long-term advantageous from long-term disadvantageous decks of cards: men choose more cards from the long-term advantageous decks ...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2012.10.002
更新日期：2013-02-01 00:00:00
abstract：:Acuity was measured in 48 prematurely born infants using the preferential looking technique. These quantitative results show that acuity development in these infants is related to conceptional rather than postnatal age, in agreement with the qualitative findings of previous studies. Severe intraventricular haemorrhage...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(83)90149-3
更新日期：1983-10-01 00:00:00
abstract：:Deep brain stimulation (DBS) has gained interest as a potential therapy for advanced treatment-resistant dementia. However, possible targets for DBS and the optimal stimulation parameters are not yet clear. Here, we compared the effects of DBS of the CA1 sub-region of the hippocampus, mammillothalamic tract, anterior ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.06.032
更新日期：2015-10-01 00:00:00
abstract：:Amplitude and habituation of the acoustic startle response were assessed in four recombinant inbred (RI) rat strains. One group from each strain underwent repeated restraint stress, the last session of which was 24h before startle testing while, a second group from each strain was not stressed prior to testing. Additi...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(03)00061-5
更新日期：2003-09-15 00:00:00
abstract：:Although drug rewards and natural rewards share neural substrates, the neuronal activation patterns and mechanisms behind the interaction between cocaine and social reward are poorly understood. Here, we investigated the conditioned place preference (CPP) in social (conspecific) vs cocaine conditioning, and the expres...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.05.010
更新日期：2016-09-01 00:00:00
abstract：:By the second postnatal week of life infant rats can acquire taste avoidance induced by amphetamine. Psychostimulant drugs supports appetitive and aversive learning in adult rats. Their appetitive effects are more likely to become associated with contextual cues, while the aversive ones have been consistently found in...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.03.018
更新日期：2012-05-16 00:00:00
abstract：:Antagonists of group I metabotropic receptors exhibit anxiolytic action in adult rats. In immature animals we demonstrated anticonvulsant action of MPEP and AIDA, antagonists of group 5 and group 1, respectively. However, there are no developmental data on anxiolytic-like and learning actions of both compounds. This s...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.05.032
更新日期：2009-12-01 00:00:00
abstract：:Sustained attention is defined as the ability or capacity to remain focused on the occurrence of rare events over long periods of time. We describe here the development of a novel, operant-based attention task that can be learned by mice in 8-10 days. Mice were trained on a 2-choice visual discrimination task in an op...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.04.036
更新日期：2009-12-01 00:00:00
abstract：:Repeated systemic administration of low doses of kainic acid (KA) induces spontaneous convulsive seizures [Hellier JL, Patrylo PR, Buckmaster PS, Dudek FE. Recurrent spontaneous motor seizures after repeated low-dose systemic treatment with kainate: assessment of a rat model of temporal lobe epilepsy. Epilepsy Res 199...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2006.03.025
更新日期：2006-07-15 00:00:00
abstract：:Behavioural, electroencephalographic and neuropathological responses to increasing doses of pilocarpine (100-400 mg/kg) administered intraperitoneally to rats were studied. At the dose of 400 mg/kg pilocarpine produced a sequence of behavioural alterations including staring spells, olfactory and gustatory automatisms ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(83)90136-5
更新日期：1983-09-01 00:00:00
abstract：:Pit vipers use infrared-sensitive pit organs to accurately target homeothermic prey even in the absence of visual cues. It has been suggested that other vipers, including large ambush predators of the genus Bitis, also may use radiant infrared information for predatory targeting. We compared behavioral responses of pi...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2004.01.020
更新日期：2004-09-23 00:00:00
abstract：:To study the role of hippocampal muscarinic receptors in spatial learning, various doses of scopolamine were injected bilaterally into the CA1 region of the dorsal hippocampus of rats trained in a two-platform spatial discrimination task. Scopolamine administered 10 min before each training session at doses ranging fr...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(97)80988-6
更新日期：1997-01-01 00:00:00
abstract：:Exposure to social stress increases the vulnerability of experimental animals to the rewarding effects of cocaine and it has been suggested that the glutamatergic system could be involved in these effects of stress. The aim of this work is to determine the role of N-methyl-d-aspartate (NMDA) glutamate receptors in the...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2018.12.025
更新日期：2019-04-01 00:00:00
abstract：:Sensory-motor development begins early during embryogenesis and is influenced by sensory experience. Little is known about the prenatal factors that influence the development of motor coordination. Here we investigated whether and to what extent prenatal light experience can influence the development of motor coordina...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.03.039
更新日期：2017-06-01 00:00:00
abstract：:The inferior olive (IO) is a required component of neural circuits controlling the classical conditioning of eyeblink responses. Previous reports indicated that lesioning or inactivating the IO abolishes conditioned eyeblinks (CRs), but there was disagreement regarding the timing of the CR performance deficit. As a re...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2006.12.012
更新日期：2007-03-12 00:00:00
abstract：:Many studies have demonstrated that aging is associated with declines in skill acquisition. In the current study, we tested whether older adults could acquire general, transferable knowledge about skill learning processes. Older adult participants learned five different motor tasks. Two older adult control groups perf...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2007.05.024
更新日期：2007-10-01 00:00:00
abstract：:Attention plays an important role in perception and cognition, and developing an effective method to train and improve attention is an essential and challenging task. In this study, fingertip-based adaptive force control tasks (AFCT) were explored for attention training, and the visual-channel task called an attention...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.03.028
更新日期：2019-12-30 00:00:00
abstract：:Blind pointing (i.e. pointing to visual targets without seeing the pointing arm) was investigated in normal subjects in response to stepwise lateral tilts (20 degrees) of the body, head, and trunk. Blind pointing positions of the right index finger on the outer surface of a hemispherical screen were measured relative ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(88)90140-4
更新日期：1988-09-15 00:00:00
abstract：:To assess the role of endogenous peptides involved in stress responsivity in the development of diet-induced obesity (DIO), selectively bred DIO and diet-resistant (DR) male were weaned onto a low fat (4.5%) chow diet at 3 weeks of age and then fed either chow or a 31% fat by energy content (high energy (HE)) diet for...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2004.03.019
更新日期：2004-10-05 00:00:00
abstract：:Treatment of anxiety disorders by either pharmacological or behavioral means is applied with the intention to directly target the limbic system or high brain centers that down-regulate limbic activity. In spite of intense and long treatment, remission is not achieved in many patients, suggesting that their pathophysio...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.06.046
更新日期：2015-01-01 00:00:00
abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder associated with cognitive deterioration and neuropsychiatric symptoms. Sensorimotor gating deficit has been identified in neuropsychiatric diseases. The aim of the present study was to evaluate the possible sensorimotor gating deficit and its correlation to memo...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.05.007
更新日期：2012-07-15 00:00:00
abstract：:Although both the presupplementary motor area (pre-SMA) and the right inferior frontal gyrus (rIFG) have been demonstrated to be critical for response inhibition, there is still considerable disagreement over the roles they play in the process. In the present study, we investigated the causal relations of the pre-SMA ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.08.024
更新日期：2016-01-01 00:00:00
