Effects of intracerebroventricular administration of ultra low doses of histaminergic drugs on morphine state-dependent memory of passive avoidance in mice.

Abstract:

:The effects of intracerebroventricular (i.c.v.) administration of ultra low doses (ULDs) of histamine, clobenpropit and pyrilamine are studied on morphine state-dependent (STD) memory in mice. Although pre-test administration of different doses of histamine and clobenpropit showed no effect on impairment of memory induced by pre-training morphine, when the above drugs were co-administered with morphine, they inhibited the restoration of memory by morphine. These effects were opposite to microgram doses of the same drugs.

journal_name

Behav Brain Res

authors

Khalilzadeh A,Zarrindast MR,Djahanguiri B

doi

10.1016/j.bbr.2005.07.014

subject

Has Abstract

pub_date

2006-01-06 00:00:00

pages

184-7

issue

1

eissn

0166-4328

issn

1872-7549

pii

S0166-4328(05)00328-1

journal_volume

166

pub_type

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