Abstract:
:Effects of aspiration lesions of the cerebral cortex on the behavioral effects of intraventricular substantia nigra grafts were investigated. Apomorphine-induced rotational behavior consequent to unilateral lesions of the substantia nigra was used as a behavioral measure. Substantia nigra grafts reduced rotational behavior in animals with sham cortical lesions. Cortical lesions also decreased rotational behavior and, in these animals, no additional decrease in rotational behavior was induced by substantia nigra grafts. It is concluded that cortical lesions alter striatal circuitry so as to preclude a behavioral effect of substantia nigra grafts.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Freed WJ,Cannon-Spoor HEdoi
10.1016/s0166-4328(89)80060-9subject
Has Abstractpub_date
1989-04-01 00:00:00pages
279-88issue
3eissn
0166-4328issn
1872-7549pii
S0166-4328(89)80060-9journal_volume
32pub_type
杂志文章abstract::The hippocampus is believed to play an important role in spatial cognition and anxiety. Much of the supporting evidence is derived from rat studies. Recent reports on hippocampal lesioned mice also showed impairments in spatial function, but anxiety was not uniformly diminished. There were, however, striking impairmen...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2004.05.027
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journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/s0166-4328(01)00367-9
更新日期:2001-12-14 00:00:00
abstract::Mice altered by transgenesis or gene targeting ("knockouts") have increasingly been employed as alternative effective tools in elucidating the genetic basis of neurophysiology and behavior. Standardization of specific behavioral paradigms and phenotyping strategies will ensure that these behavioral mouse mutants offer...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(01)00284-4
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(00)00328-4
更新日期:2001-02-15 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/0166-4328(93)90100-5
更新日期:1993-12-20 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.07.046
更新日期:2014-11-01 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2009.10.033
更新日期:2010-03-05 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/j.bbr.2012.09.025
更新日期:2013-01-15 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.05.009
更新日期:2015-09-15 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2007.07.030
更新日期:2008-01-10 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.08.022
更新日期:2014-11-01 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(00)00228-x
更新日期:2000-09-01 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.01.009
更新日期:2016-04-01 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2019.111937
更新日期:2019-09-16 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00051-7
更新日期:2002-08-21 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.10.050
更新日期:2012-02-01 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.12.024
更新日期:2019-04-01 00:00:00
abstract::A neurochemical study of the transsynaptic interactions established between septal GABAergic interneurones and cholinergic septo-hippocampal neurones was conducted using mice. The effects of acute in vivo injections of either muscimol (20-500 ng/0.2 microliter), bicuculline (100 ng-1 micrograms/0.2 microliter) or sali...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(05)80297-9
更新日期:1992-09-28 00:00:00
abstract::Single pulse electrical stimulation of the sensorimotor cortex in waking rats produced an evoked response in the contralateral sensorimotor cortex. The slow wave response consisted of: (1) an early component that was negative at the pial surface and in layer V, and was associated with multiunit discharge; and (2) a la...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(87)90043-x
更新日期:1987-07-01 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.04.025
更新日期:2018-03-15 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2004.05.001
更新日期:2004-12-06 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2020.112903
更新日期:2021-01-01 00:00:00
abstract::Hypobaric hypoxia (HH), a predisposing environmental condition at high altitude (HA) encountered by many mountaineers jeopardizes their normal physiology like motor coordination and cognitive functions. Our previous studies revealed that the HH induces oxidative stress and neurodegeneration, which is associated with s...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2008.01.007
更新日期:2008-06-03 00:00:00
abstract::The involvement of the motor system in action language comprehension is a hotly debated topic in cognitive neuroscience and psychology. Recent studies suggest that primary motor cortex (M1) response to action language is context-sensitive rather than automatic and necessary. Specifically, semantic polarity (i.e. affir...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.09.019
更新日期:2018-01-15 00:00:00
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journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(81)90060-7
更新日期:1981-03-01 00:00:00
abstract::Expression of Schaffer collateral-CA1 long-term potentiation (LTP) and long-term depression (LTD) was not affected in hippocampal slices from wild-type mice pretreated with lipopolysaccharide (0.25mg/kg, i.p.), to increase interleukin-18 (IL-18) concentrations in the brain. For IL-18 knock-out (IL-18 KO) mice, the LTP...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2009.08.033
更新日期:2010-01-05 00:00:00
abstract::The central visual system of white zebra finches is physiologically and anatomically different from normally coloured (wild type) animals. The main difference to normal birds is an enhanced response to ipsilateral stimulation in all areas of the tectofugal visual pathway. Previous experiments indicated that besides an...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.02.016
更新日期:2006-06-03 00:00:00
abstract::Pavlovian conditioning of immune functions provided early impetus to the rapidly expanding knowledge of bi-directional communication among the immune, endocrine, and central nervous systems. Since these early investigations, the phenomenology of this response has been well characterized. However the neural mechanisms ...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/s0166-4328(99)00191-6
更新日期:2000-06-01 00:00:00
abstract::The central 5-hydroxytryptamine (5-HT; serotonin) system is well established as an important regulator of appetite and continues to remain a focus of obesity research. While much emphasis has focussed on the 5-HT(2C) receptor (5-HT(2C)R) in 5-HT's anorectic effect, pharmacological manipulation of the 5-HT₆ receptor (5...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.02.018
更新日期:2014-06-01 00:00:00
abstract::Though growing evidence implicates both melatonin (MLT) and its immediate precursor N-acetylserotonin (NAS) in the regulation of hippocampal neurogenesis, their comparative mechanistic relationship with core behavioural correlates of psychiatric disorders is largely unknown. To address this issue, we investigated the ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.10.027
更新日期:2016-01-15 00:00:00