Transcallosal evoked potentials in relation to behavior in the rat: effects of atropine, p-chlorophenylalanine, reserpine, scopolamine and trifluoperazine.

Abstract:

:Single pulse electrical stimulation of the sensorimotor cortex in waking rats produced an evoked response in the contralateral sensorimotor cortex. The slow wave response consisted of: (1) an early component that was negative at the pial surface and in layer V, and was associated with multiunit discharge; and (2) a late component that was mainly negative at the surface, positive in layer V, and was associated with multiunit suppression. Previous research suggests that the early component represents summed excitatory postsynaptic potentials; the late component summed inhibitory postsynaptic potentials. Both components could be elicited by direct stimulation of the corpus callosum and both were abolished by midline callosal section. The amplitude and duration of the late component varied with concurrent motor activity in a striking manner. It was large during waking immobility and also during face-washing, licking the paws, chewing food and drinking water, but was much reduced or absent during head movements, walking and changes in posture. Only minor changes were associated with the transition from waking immobility to slow wave sleep. A series of pharmacological experiments indicated that the behavior-related variation in the late component of the transcallosal evoked response was dependent on both cholinergic and serotonergic transmission.

journal_name

Behav Brain Res

authors

Vanderwolf CH,Harvey GC,Leung LW

doi

10.1016/0166-4328(87)90043-x

subject

Has Abstract

pub_date

1987-07-01 00:00:00

pages

31-48

issue

1

eissn

0166-4328

issn

1872-7549

pii

0166-4328(87)90043-X

journal_volume

25

pub_type

杂志文章
  • Modulation of synaptic plasticity by short-term aerobic exercise in adult mice.

    abstract::Physiological effects of different types, of continuous and interval aerobic training, have been largely described and studied in the adult man. It was previously indicated that interval training plays an important role in maximizing both peripheral muscle and central cardiorespiratory adaptations, permitting signific...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2017.05.058

    authors: D'Arcangelo G,Triossi T,Buglione A,Melchiorri G,Tancredi V

    更新日期:2017-08-14 00:00:00

  • Visual pathways and acuity hooded rats.

    abstract::Three experiments on the effects of lesions of the visual system on contrast-detection in hooded rats are described, in which the ability of rats to detect stationary high-contrast square-wave gratings of various fundamental frequencies presented in the central visual field was measured before and after operation. The...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(81)90050-4

    authors: Dean P

    更新日期:1981-09-01 00:00:00

  • To the self and beyond: Arousal and functional connectivity of the temporo-parietal junction contributes to spontaneous sensations perception.

    abstract::The temporoparietal junction (TPJ), along with the anterior insula (AI) and the extrastriate body area (EBA), play a major part in embodiment and self-awareness. However, these connections also appear to be frequently engaged in arousal and attentional processing of external events. Considering that these networks may...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2020.112880

    authors: Salgues S,Plancher G,Jacquot L,Naveteur J,Fanuel L,Gálvez-García G,Michael GA

    更新日期:2021-01-01 00:00:00

  • Spontaneous recovery from extinction in the infant rat.

    abstract::Within the Pavlovian conditioning framework, extinction is a procedure in which, after conditioning, the conditioned stimulus (CS) is repeatedly presented without the unconditioned stimulus (US). During this procedure the conditioned response (CR) is gradually attenuated. It has been suggested that extinction during t...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.08.009

    authors: Revillo DA,Paglini MG,Arias C

    更新日期:2014-11-01 00:00:00

  • Learning and memory in streptozotocin-induced diabetic rats in a novel spatial/object discrimination task.

    abstract::Diabetes mellitus is associated with disturbances of cognitive functioning. The aim of this study was to examine cognitive functioning in diabetic rats using the 'Can test', a novel spatial/object learning and memory task, without the use of aversive stimuli. Rats were trained to select a single rewarded can from seve...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(01)00186-3

    authors: Popoviç M,Biessels GJ,Isaacson RL,Gispen WH

    更新日期:2001-08-01 00:00:00

  • Insular cortex lesions alter conditioned taste avoidance in rats differentially when using two methods of sucrose delivery.

    abstract::The insular gustatory cortex may be essential for the evaluation of saliency and representation of the incentive values of tastes. Gustatory cortex lesions should interfere with conditioned taste avoidance according to these factors, which depend on the conditioned taste avoidance protocol used. The present study was ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2003.12.011

    authors: Fresquet N,Angst MJ,Sandner G

    更新日期:2004-08-31 00:00:00

  • Spatial learning induces neurogenesis in the avian brain.

    abstract::It is known from previous work that neurones are born continuously in the ventricular zone of the bird brain. In this study, we show that the amount of cell proliferation in the ventricular zone of the hippocampus (HP) and the hyperstriatum ventrale (HV) is influenced by behavioural experience. Two groups of birds (ma...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(97)00051-x

    authors: Patel SN,Clayton NS,Krebs JR

    更新日期:1997-12-01 00:00:00

  • Interaction between subclinical doses of the Parkinson's disease associated gene, α-synuclein, and the pesticide, rotenone, precipitates motor dysfunction and nigrostriatal neurodegeneration in rats.

    abstract::In most patients, Parkinson's disease is thought to emerge after a lifetime of exposure to, and interaction between, various genetic and environmental risk factors. One of the key genetic factors linked to this condition is α-synuclein, and the α-synuclein protein is pathologically associated with idiopathic cases. Ho...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2016.08.056

    authors: Naughton C,O'Toole D,Kirik D,Dowd E

    更新日期:2017-01-01 00:00:00

  • Valproic acid effects in the hippocampus and prefrontal cortex in an animal model of post-traumatic stress disorder.

    abstract::Reactive oxygen species (ROS) and pro-inflammatory cytokines (PIC) are upregulated in post-traumatic stress disorder (PTSD). Histone deacetylase inhibitors (HDACi) modify genetic transcription and can diminish ROS and PIC escalation. They can also modulate levels of neurotransmitters such as catecholamines and seroton...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.03.029

    authors: Wilson CB,McLaughlin LD,Ebenezer PJ,Nair AR,Francis J

    更新日期:2014-07-15 00:00:00

  • Effect of prefrontal transcranial magnetic stimulation on spontaneous truth-telling.

    abstract::Brain-process foundations of deceptive behaviour have become a subject of intensive study both in fundamental and applied neuroscience. Recently, utilization of transcranial magnetic stimulation has enhanced methodological rigour in this research because in addition to correlational studies causal effects of the disti...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2011.07.028

    authors: Karton I,Bachmann T

    更新日期:2011-11-20 00:00:00

  • Gene expression profiling in brain regions of a rat model displaying schizophrenia-related features.

    abstract::Animal models allow insights into complex neurodevelopmental disorders. Apomorphine-susceptible rats (so-called APO-SUS rats) provide a model that displays a complex phenotype with schizophrenia-related features and together with its phenotypic counterpart (APO-UNSUS rats) has been independently generated twice (origi...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2009.10.042

    authors: Van Schijndel JE,Van Zweeden M,Van Loo KM,Martens GJ

    更新日期:2010-03-05 00:00:00

  • The postnatal origin of adult neural stem cells and the effects of glucocorticoids on their genesis.

    abstract::The relevance of adult neurogenesis in hippocampal function is well documented, as is the potential impact stress has on the adult neurogenic niche. Adult born neurons are generated from neural precursors in the dentate gyrus (DG), although the point in postnatal development that these cell precursors originate is not...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.11.013

    authors: Ortega-Martínez S,Trejo JL

    更新日期:2015-02-15 00:00:00

  • Coordinated movement is influenced by prenatal light experience in bobwhite quail chicks (Colinus virginianus).

    abstract::Sensory-motor development begins early during embryogenesis and is influenced by sensory experience. Little is known about the prenatal factors that influence the development of motor coordination. Here we investigated whether and to what extent prenatal light experience can influence the development of motor coordina...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2017.03.039

    authors: Belnap SC,Lickliter R

    更新日期:2017-06-01 00:00:00

  • Neurotransmissions of antidepressant-like effects of neuromedin U-23 in mice.

    abstract::Neuromedin U (NmU) is a widely distributed and multifunctional peptide in the central nervous system and the peripheral tissues. Little is know about the mechanisms of NmU on brain functions. The rodent isoform of the NmU, NmU-23, has been shown to have anxiolytic effects involved in the β-adrenergic and cholinergic n...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2013.11.005

    authors: Tanaka M,Telegdy G

    更新日期:2014-02-01 00:00:00

  • Orientational asymmetries in small-field optokinetic nystagmus in human infants.

    abstract::Optokinetic nystagmus (OKN) is a pattern of reflexive eye movements which occurs when portions of the visual field are in continuous motion. Gratings moving at 7 deg/s either horizontally (left or right) or vertically (up or down) were presented on a viewing screen subtending 30 degrees by 22 degrees. Horizontal (HOKN...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(84)90164-5

    authors: Hainline L,Lemerise E,Abramov I,Turkel J

    更新日期:1984-09-01 00:00:00

  • Social isolation stress during the third week of life has age-dependent effects on spatial learning in rats.

    abstract::Despite extensive research on the relationship between acute stress and hippocampal function in adults, little is known about the short- and long-term effects of prolonged juvenile stress on learning, memory, and other hippocampal functions. This experiment investigated whether spatial learning would be altered in juv...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(01)00315-1

    authors: Frisone DF,Frye CA,Zimmerberg B

    更新日期:2002-01-22 00:00:00

  • Differential effects of spaced vs. massed training in long-term object-identity and object-location recognition memory.

    abstract::Here we tested whether the well-known superiority of spaced training over massed training is equally evident in both object identity and object location recognition memory. We trained animals with objects placed in a variable or in a fixed location to produce a location-independent object identity memory or a location...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2013.04.047

    authors: Bello-Medina PC,Sánchez-Carrasco L,González-Ornelas NR,Jeffery KJ,Ramírez-Amaya V

    更新日期:2013-08-01 00:00:00

  • Mapping of stimulus features and meaning in gerbil auditory cortex with 2-deoxyglucose and c-Fos antibodies.

    abstract::The basic functional organization of gerbil auditory cortex was previously mapped with unit recording of best frequency and with the fluoro-2-deoxyglucose mapping (FDG) technique. Among at least seven subfields in this cortex the primary auditory cortex (AI) and the anterior auditory field (AAF) showed prominent tonot...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(94)00140-b

    authors: Scheich H,Zuschratter W

    更新日期:1995-01-23 00:00:00

  • Paternal physical exercise demethylates the hippocampal DNA of male pups without modifying the cognitive and physical development.

    abstract::Maternal exercise is known to have beneficial effects in progeny development, but the influence of paternal exercise on the offspring still unclear. Since spermatogenesis is a continuous process, the father's life experiences can reprogram epigenetic content of the sperm and somehow interfere on offspring phenotype. T...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2018.03.040

    authors: Mega F,de Meireles ALF,Piazza FV,Spindler C,Segabinazi E,Dos Santos Salvalaggio G,Achaval M,Marcuzzo S

    更新日期:2018-08-01 00:00:00

  • Cognitive functions of the basal forebrain cholinergic system in monkeys: memory or attention?

    abstract::The cholinergic hypothesis of memory dysfunction originally proposed that dysfunction of cholinergic neurons in the basal forebrain cholinergic system (BFCS) may be responsible for the memory deficits associated with aging and Alzheimer's disease (AD). This hypothesis directed focus on the BFCS in experimental animal ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/0166-4328(95)00143-3

    authors: Voytko ML

    更新日期:1996-02-01 00:00:00

  • Behavioural changes observed in demyelination model shares similarities with white matter abnormalities in humans.

    abstract::Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Further to the symptoms resulting from demyelination, new studies point to the involvement of neuroinflammation and white matter abnormalities in psychiatric disorders and neurodegenerative diseases. Cuprizon...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2015.03.038

    authors: Serra-de-Oliveira N,Boilesen SN,Prado de França Carvalho C,LeSueur-Maluf L,Zollner Rde L,Spadari RC,Medalha CC,Monteiro de Castro G

    更新日期:2015-01-01 00:00:00

  • Short-term full kindling of the amygdala dissociates natural and periaqueductal gray-evoked flight behaviors of the rat.

    abstract::Panic attacks present a high comorbidity with agoraphobia, separation anxiety and generalized anxiety disorder. Nevertheless, while panic attacks have been frequently equated to fear, the relationship of panic disorder with specific phobias remains uncertain. The combination of experimental models of panic and phobias...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2008.11.042

    authors: Tannure RM,Bittencourt AS,Schenberg LC

    更新日期:2009-05-16 00:00:00

  • Graded unilateral cervical spinal cord injury in the rat: evaluation of forelimb recovery and histological effects.

    abstract::The purpose of this study was to develop a model of unilateral cervical (C4-C5) spinal cord contusion injury in the rat and to characterize the functional and histological consequences following three injury levels using a new weight-drop spinal cord injury device. We evaluated forepaw/forelimb and hindlimb functions ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(00)00328-4

    authors: Soblosky JS,Song JH,Dinh DH

    更新日期:2001-02-15 00:00:00

  • The mating movements of male decorticate rats: evidence for subcortically generated movements by the male but regulation of approaches by the female.

    abstract::The study shows that although many features of copulation in decorticate male rats are normal, copulatory success is importantly dependent upon the control of approaches exerted by the normal female rat. Copulation by neonatally decorticated adult rats and normal adult rats was studied in cohabitation and videotaped t...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(85)90042-7

    authors: Whishaw IQ,Kolb B

    更新日期:1985-10-01 00:00:00

  • Fluoxetine and stress inversely modify lateral septal nucleus-mpfc neuronal responsivity.

    abstract::Several clinically effective antidepressants increase the neuronal firing rate in the lateral septal nucleus (LSN), a forebrain structure that is anatomically related to medial prefrontal cortex (mPFC) regions. mPFC function is related to depression and the regulation of fear. However, unknown is whether antidepressan...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2018.06.007

    authors: Contreras CM,Gutiérrez-García AG,Sánchez-Salcedo JA

    更新日期:2018-10-01 00:00:00

  • Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression.

    abstract::Accumulating evidence shows that stressful events evoke molecular alterations in the brain, considered a pathology in major depressive disorder (MDD). However, the abnormalities of neurotransmissions as well as intracellular signaling pathways affected by chronic stress in brain have not been fully explored. We invest...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2019.112053

    authors: Lu Q,Mouri A,Yang Y,Kunisawa K,Teshigawara T,Hirakawa M,Mori Y,Yamamoto Y,Libo Z,Nabeshima T,Saito K

    更新日期:2019-10-17 00:00:00

  • Intrahippocampal administration of 5-HT6 receptor drugs on memory consolidation and amnesia protocols.

    abstract::To our knowledge the intrahippocampal serotonergic 5-HT6 receptor tone on memory and amnesia models remains unexplored. Hence, in the present work we tested intrahippocampal administration of serotonin or 5-hydroxytryptamine (5-HT)6 receptor experimental molecules with differential intrinsic activity. Methods: In the ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2018.11.021

    authors: Aparicio-Nava L,Tellez R,Gonzalez R,Liy-Salmeron G,Meneses A

    更新日期:2019-02-01 00:00:00

  • C57BL/6 substrain differences in formalin-induced pain-like behavioral responses.

    abstract::Substantial evidence from preclinical models of pain suggests that basal and noxious nociceptive sensitivity, as well as antinociceptive responses to drugs, show significant heritability. Individual differences to these responses have been observed across species from rodents to humans. The use of closely related C57B...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2020.112698

    authors: Ulker E,Caillaud M,Patel T,White A,Rashid D,Alqasem M,Lichtman AH,Bryant CD,Damaj MI

    更新日期:2020-07-15 00:00:00

  • Near-infrared imaging of the effects of glucose ingestion and regulation on prefrontal activation during dual-task execution in healthy fasting older adults.

    abstract:RATIONALE:Glucose enhancing effects in older adults have mostly been observed for episodic memory, but have recently been found for attentional control performance. Yet, brain activation patterns underlying these effects are still unknown. OBJECTIVE:The present study examined the acute effects of glucose ingestion on ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2012.03.039

    authors: Gagnon C,Desjardins-Crépeau L,Tournier I,Desjardins M,Lesage F,Greenwood CE,Bherer L

    更新日期:2012-06-15 00:00:00

  • Evaluation of spontaneous recovery of behavioral and brain injury profiles in zebrafish after hypoxia.

    abstract::Cerebral hypoxia-ischemia can lead to motor and sensory impairments which can be dependent on the extent of infarcted regions. Since a better understanding of the neurochemical mechanisms involved in this injury is needed, the use of zebrafish as a cerebral hypoxia model has become quite promising because it could imp...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2013.07.019

    authors: Braga MM,Rico EP,Córdova SD,Pinto CB,Blaser RE,Dias RD,Rosemberg DB,Oliveira DL,Souza DO

    更新日期:2013-09-15 00:00:00