Orientational asymmetries in small-field optokinetic nystagmus in human infants.

Abstract:

:Optokinetic nystagmus (OKN) is a pattern of reflexive eye movements which occurs when portions of the visual field are in continuous motion. Gratings moving at 7 deg/s either horizontally (left or right) or vertically (up or down) were presented on a viewing screen subtending 30 degrees by 22 degrees. Horizontal (HOKN) and vertical (VOKN) OKN were recorded under binocular viewing conditions from infants and adults. Eye movements were recorded by means of an infrared corneal reflection eye movement recorder. OKN to horizontal and vertical stimuli was different in pattern for infants. Infants' HOKN was of significantly higher frequency and lower amplitude than their VOKN. Infants below 4 months of age also showed an asymmetry within VOKN between upward and downward stimulus motion, with markedly lower gains and more variable slow phase following movements for downward moving stimuli. No differences were found in HOKN to the right and left. There was also no evidence of a build-up of slow phase velocity over time. Infants' fast phases showed peak velocity/amplitude relationships like those of adults, and like those of infant saccades recorded in a previous study of infants' fast eye movements. Across all directions of stimulus movement, infants had lower slow phase gains and OKN frequencies, and larger slow phase amplitudes than adults. The characteristics of infants' OKN are discussed in relation to those observed in other species and in adult clinical patients with eye movement disorders.

journal_name

Behav Brain Res

authors

Hainline L,Lemerise E,Abramov I,Turkel J

doi

10.1016/0166-4328(84)90164-5

subject

Has Abstract

pub_date

1984-09-01 00:00:00

pages

217-30

issue

3

eissn

0166-4328

issn

1872-7549

pii

0166-4328(84)90164-5

journal_volume

13

pub_type

杂志文章
  • Temporal patterns analysis of rat behavior in hole-board.

    abstract::The aim of present research was to analyze the temporal structure of rodent's anxiety-related behavior in hole-board apparatus (HB). Fifteen male Wistar rats were tested for 10 min. Video files, collected for each subject, were coded by means of a software coder and event log files generated for each subject. To asses...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2009.11.013

    authors: Casarrubea M,Sorbera F,Magnusson M,Crescimanno G

    更新日期:2010-03-17 00:00:00

  • Synergistic effects of age and stress in a rodent model of stroke.

    abstract::Ageing and stress represent critical influences on stroke risk and outcome. These variables are intricately linked, as ageing is frequently associated with gradual dysregulation of the hypothalamic-pituitary-adrenal axis. This study determined the effects of stress on motor function in aged rats, and explored possible...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2010.04.035

    authors: Merrett DL,Kirkland SW,Metz GA

    更新日期:2010-12-06 00:00:00

  • Helium preconditioning protects the brain against hypoxia/ischemia injury via improving the neurovascular niche in a neonatal rat model.

    abstract::This study aimed to investigate whether helium preconditioning (He-PC) is able to exert neuroprotective effects via improving focal neurovascular niche in a neonatal rat hypoxia/ischemia (HI) brain injury model. Seven day old rat pups were divided into control group, HI group and He-PC group. HI was induced by exposur...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2016.08.015

    authors: Li Y,Zhang P,Liu Y,Liu W,Yin N

    更新日期:2016-11-01 00:00:00

  • The effect of constant darkness and circadian resynchronization on the recovery of alcohol hangover.

    abstract::Alcohol hangover (AH) is a particular state after binge-like drinking. AH begins when ethanol is absent in plasma and is characterized by a cluster of physical and psychological symptoms. Alcohol disrupts circadian patterns of behavioral and physiological parameters; however, the involvement of circadian clock on the ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.03.048

    authors: Karadayian AG,Lores-Arnaiz S,Cutrera RA

    更新日期:2014-07-15 00:00:00

  • The role of the medial olfactory pathways in olfaction: behavioral and electrophysiological data.

    abstract::The role of the olfactory inputs transmitted by the medial olfactory pathways --i.e. anterior limb of the anterior commissure and medial forebrain bundle-was studied in rats submitted either to a bilateral lesion of the anterior commissure (bAC group) or to a bilateral transection of the lateral olfactory tract follow...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(82)90017-1

    authors: Cattarelli M

    更新日期:1982-12-01 00:00:00

  • H₂S attenuates cognitive deficits through Akt1/JNK3 signaling pathway in ischemic stroke.

    abstract::Neuronal damage in the hippocampal formation which is more sensitive to ischemic stimulation and easily injured will cause severe learning and memory impairment. Therefore, inhibiting hippocampal neuron injuries is the main contributor for learning and memory impairment during cerebral ischemia. Hydrogen sulfide (H2S)...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.04.027

    authors: Wen X,Qi D,Sun Y,Huang X,Zhang F,Wu J,Fu Y,Ma K,Du Y,Dong H,Liu Y,Liu H,Song Y

    更新日期:2014-08-01 00:00:00

  • Contributions of the basal ganglia and functionally related brain structures to motor learning.

    abstract::This review discusses the cerebral plasticity, and the role of the cortico-striatal system in particular, observed as one is learning or planning to execute a newly learned motor behavior up to when the skill is consolidated or has become highly automatized. A special emphasis is given to imaging work describing the n...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.bbr.2008.11.012

    authors: Doyon J,Bellec P,Amsel R,Penhune V,Monchi O,Carrier J,Lehéricy S,Benali H

    更新日期:2009-04-12 00:00:00

  • Hippocampal theta activity related to elicitation and inhibition of approach locomotion.

    abstract::This study determined if the hippocampal theta rhythm showed phase relationships or changes in amplitude and frequency with the onset of stimuli and locomotion in a task in which auditory cues initiated and suppressed approach locomotion. Rats with electrodes in the dorsal hippocampus lapped at a milk dipper and were ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2004.12.006

    authors: Sinnamon HM

    更新日期:2005-05-28 00:00:00

  • Interactions between Aβ oligomers and presynaptic cholinergic signaling: age-dependent effects on attentional capacities.

    abstract::Substantial evidence suggests that cerebral deposition of the neurotoxic fibrillar form of amyloid precursor protein, β-amyloid (Aβ), plays a critical role in the pathogenesis of Alzheimer's disease (AD). Yet, many aspects of AD pathology including the cognitive symptoms and selective vulnerability of cortically proje...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.07.046

    authors: Parikh V,Bernard CS,Naughton SX,Yegla B

    更新日期:2014-11-01 00:00:00

  • Fluoxetine and stress inversely modify lateral septal nucleus-mpfc neuronal responsivity.

    abstract::Several clinically effective antidepressants increase the neuronal firing rate in the lateral septal nucleus (LSN), a forebrain structure that is anatomically related to medial prefrontal cortex (mPFC) regions. mPFC function is related to depression and the regulation of fear. However, unknown is whether antidepressan...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2018.06.007

    authors: Contreras CM,Gutiérrez-García AG,Sánchez-Salcedo JA

    更新日期:2018-10-01 00:00:00

  • D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI.

    abstract::Both the serotonin and glutamate systems have been implicated in the pathophysiology of schizophrenia, as well as in the mechanism of action of antipsychotic drugs. Psychedelic drugs act through the serotonin 2A receptor (5-HT2AR), and elicit a head-twitch response (HTR) in mice, which directly correlates to 5-HT2AR a...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2013.11.022

    authors: Santini MA,Balu DT,Puhl MD,Hill-Smith TE,Berg AR,Lucki I,Mikkelsen JD,Coyle JT

    更新日期:2014-02-01 00:00:00

  • Neonatal exposure to LPS leads to heightened exploratory activity in adolescent rats.

    abstract::Although several reports have demonstrated physiological and behavioral changes in adult rats due to neonatal immune challenges, little is known about their effects in adolescence. Since neonatal exposure to lipopolysaccharide (LPS) alters the neural substrates involved in cognitive disorders, we tested the hypothesis...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2010.07.001

    authors: Rico JL,Ferraz DB,Ramalho-Pinto FJ,Morato S

    更新日期:2010-12-20 00:00:00

  • Serotonergic modulation of septo-hippocampal and septo-mammillary theta activity during spatial learning, in the rat.

    abstract::Theta activity has been related to the processing of spatial information and the formation of hippocampus-dependent memory. The medial septum (MS) plays an important role in the control and coordination of theta activity, as well as in the modulation of learning. It has been established that increased serotonergic act...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2016.11.017

    authors: Gutiérrez-Guzmán BE,Hernández-Pérez JJ,Olvera-Cortés ME

    更新日期:2017-02-15 00:00:00

  • NK₃ receptor agonism reinstates temporal order memory in the hemiparkinsonian rat.

    abstract::Animals treated with unilateral 6-hydroxydopamine (6-ODHA) injections, an animal model of Parkinson's disease, exhibit deficits in memory for temporal order, but show intact novel object recognition. Since senktide, a potent neurokinin-3 receptor (NK3-R) agonist, has been shown to have promnestic effects in the aged r...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.06.006

    authors: Chao OY,Wang AL,Nikolaus S,de Souza Silva MA

    更新日期:2015-05-15 00:00:00

  • Barnes maze performance of Octodon degus is gender dependent.

    abstract::Gender differences in spatial navigation have been widely reported in nocturnal rodent species. Here, for the first time we report gender differences in spatial learning and memory of Octodon degus, a long-lived diurnal hystricomorph rodent. In the present study, 16 months old male and female O. degus were tested in t...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2010.04.005

    authors: Popović N,Madrid JA,Rol MA,Caballero-Bleda M,Popović M

    更新日期:2010-10-15 00:00:00

  • Light experience and the development of behavioural lateralisation in chicks. II. Choice of familiar versus unfamiliar model social partner.

    abstract::In late-stage embryos of domestic fowl, exposure of the right eye to light entering through the shell induces asymmetry of the thalamofugal visual pathway, together with differences in performance according to whether the right or left eye (RE, LE) is in use (Behav. Brain Res. 38 (1990) 211). Nevertheless, at least so...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2004.04.016

    authors: Andrew RJ,Johnston AN,Robins A,Rogers LJ

    更新日期:2004-11-05 00:00:00

  • Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB.

    abstract::Mucopolysaccharidosis IIIB (MPSIIIB) is a lysosomal storage disease characterised by progressive central nervous system degeneration in patients, with death usually in the late teens. Serious behavioural problems have been reported in children at the early stages of the disease, such as hyperactivity and severe sleep ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2010.01.045

    authors: Canal MM,Wilkinson FL,Cooper JD,Wraith JE,Wynn R,Bigger BW

    更新日期:2010-06-19 00:00:00

  • NMDA antagonists potentiate scopolamine-induced amnesic effect.

    abstract::The effects of N-methyl-D-aspartate NMDA receptor antagonists on scopolamine-induced amnesia and on delay-interposed short-term memory performance were investigated using an 8-arm radial maze in rats. Scopolamine, a muscarinic antagonist, deteriorated the radial maze performance, while MK-801, an NMDA receptor channel...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(97)86075-5

    authors: Li HB,Matsumoto K,Tohda M,Yamamoto M,Watanabe H

    更新日期:1997-02-01 00:00:00

  • Conditioned inhibition of the nictitating membrane response in decorticate rabbits.

    abstract::Rabbits with substantial neocortical ablation were trained in a Pavlovian conditioned inhibition task using a light as the reinforced conditioned stimulus (CS) and the same light compounded with a tone as the non-reinforced CS. The conditioned response was the nictitating membrane response, and the unconditioned stimu...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(80)90037-6

    authors: Moore JW,Yeo CH,Oakley DA,Russell IS

    更新日期:1980-10-01 00:00:00

  • Cognitive functions of the basal forebrain cholinergic system in monkeys: memory or attention?

    abstract::The cholinergic hypothesis of memory dysfunction originally proposed that dysfunction of cholinergic neurons in the basal forebrain cholinergic system (BFCS) may be responsible for the memory deficits associated with aging and Alzheimer's disease (AD). This hypothesis directed focus on the BFCS in experimental animal ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/0166-4328(95)00143-3

    authors: Voytko ML

    更新日期:1996-02-01 00:00:00

  • Locomotor sites mapped with low current stimulation in intact and kainic acid damaged hypothalamus of anesthetized rats.

    abstract::To determine whether local neurons mediated the locomotor effects of electrical stimulation of the lateral hypothalamus, kainic acid injections (0.5-1.25 micrograms), intended to destroy neural somata as opposed to fibers of passage, were made unilaterally in the tuberal-posterior hypothalamus of 22 rats. The area of ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(05)80096-8

    authors: Sinnamon HM,Marciello M,Goerner DW

    更新日期:1991-12-13 00:00:00

  • Preservation of perceptual integration improves temporal stability of bimanual coordination in the elderly: an evidence of age-related brain plasticity.

    abstract::Despite the apparent age-related decline in perceptual-motor performance, recent studies suggest that the elderly people can improve their reaction time when relevant sensory information are available. However, little is known about which sensory information may improve motor behaviour itself. Using a synchronization ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.08.043

    authors: Blais M,Martin E,Albaret JM,Tallet J

    更新日期:2014-12-15 00:00:00

  • Hippocampal nerve growth factor levels are related to spatial learning ability in aged rats.

    abstract::Brain nerve growth factor (NGF) was determined in two groups of aged rats: 'good' and 'poor' performers. The animals were selected out of a population of 40 aged rats (26-28 months old) trained in a spatial learning task. Animals performing well in the test had significantly higher NGF in the hippocampus when compared...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(05)80134-2

    authors: Henriksson BG,Söderström S,Gower AJ,Ebendal T,Winblad B,Mohammed AH

    更新日期:1992-05-08 00:00:00

  • Comparisons of hemi-inattention produced by unilateral lesions of the posterior parietal cortex or medial agranular prefrontal cortex in rats: neglect, extinction, and the role of stimulus distance.

    abstract::Neglect in human and non-human primates has been demonstrated following unilateral lesions of both posterior parietal and prefrontal areas. While it has now been well established that a unilateral lesion of the rodent analog of dorsolateral prefrontal cortex, medial agranular cortex (AGm), results in neglect, the effe...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(93)90070-7

    authors: King VR,Corwin JV

    更新日期:1993-04-30 00:00:00

  • The functional neuroanatomy of depression: distinct roles for ventromedial and dorsolateral prefrontal cortex.

    abstract::A primary aim in the neuroscientific study of depression is to identify the brain areas involved in the pathogenesis of symptoms. In this review, we describe evidence from studies employing various experimental approaches in humans (functional imaging, lesion method, and brain stimulation) that converge to implicate t...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.bbr.2009.03.004

    authors: Koenigs M,Grafman J

    更新日期:2009-08-12 00:00:00

  • Rat strain-dependent effects of repeated stress on the acoustic startle response.

    abstract::Amplitude and habituation of the acoustic startle response were assessed in four recombinant inbred (RI) rat strains. One group from each strain underwent repeated restraint stress, the last session of which was 24h before startle testing while, a second group from each strain was not stressed prior to testing. Additi...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(03)00061-5

    authors: Conti LH,Printz MP

    更新日期:2003-09-15 00:00:00

  • Anti-RAGE antibody attenuates isoflurane-induced cognitive dysfunction in aged rats.

    abstract::Several animal studies demonstrated that the volatile anesthetic isoflurane could influence the blood-brain barrier (BBB) integrity, which involved the cognitive impairment. Increasing evidence has also shown that the receptor for advanced glycation end-products (RAGE) played a major role in maintaining the integrity ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2017.01.012

    authors: Shi C,Yi D,Li Z,Zhou Y,Cao Y,Sun Y,Chui D,Guo X

    更新日期:2017-03-30 00:00:00

  • Neonatal tactile stimulation reverses alterations in fine structure of small, but not large myelinated fibers, from the optic nerve of iron-deficient rats: A size-based selectivity.

    abstract::Iron is the most common micronutrient deficiency in the world and it is most prevalent in young children, exposing their developing brain to inadequate iron levels. The damage related to neuroanatomical parameters is not reversed after iron treatment. However, evidence suggest that tactile stimulation (TS) may offer g...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2019.112357

    authors: Horiquini-Barbosa E,Gibb R,Kolb B,Bray D,Lachat JJ

    更新日期:2020-02-03 00:00:00

  • Pavlovian conditioning of immune function: animal investigation and the challenge of human application.

    abstract::Pavlovian conditioning of immune functions provided early impetus to the rapidly expanding knowledge of bi-directional communication among the immune, endocrine, and central nervous systems. Since these early investigations, the phenomenology of this response has been well characterized. However the neural mechanisms ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/s0166-4328(99)00191-6

    authors: Exton MS,von Auer AK,Buske-Kirschbaum A,Stockhorst U,Göbel U,Schedlowski M

    更新日期:2000-06-01 00:00:00

  • Nature vs. nurture: can enrichment rescue the behavioural phenotype of BDNF heterozygous mice?

    abstract::In earlier experiments we have demonstrated that group-housing in a rather impoverished "standard" environment can be a crucial stress factor in male C57Bl/6 mice. The present study aimed at investigating the effect of combining a probable genetic vulnerability--postulated by the "Neurotrophin Hypothesis of Depression...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2008.04.015

    authors: Chourbaji S,Brandwein C,Vogt MA,Dormann C,Hellweg R,Gass P

    更新日期:2008-10-10 00:00:00