Abstract：
:We reviewed the records of 1,323 patients with retinoblastoma treated here between 1922 and 1978. Twenty-eight patients underwent bilateral enucleation alone and received no additional treatment for their advanced tumors. Of the 28 patients, 22 (92%) survived. Four patients were lost to follow-up, and two died of metastatic retinoblastoma. Of 22 survivors of bilateral retinoblastoma treated with enucleation alone, three developed second tumors at a mean of 15.3 years after bilateral enucleation. One patient developed a rhabdomyosarcoma in the left temple region, the second patient developed an osteogenic sarcoma of the right femur, and the third developed a malignant melanoma of the left thigh. All three patients died of their disease. The incidence of second tumors in patients who survived bilateral retinoblastoma treated without radiation was 14% (three patients), which is comparable to a series previously reported in which patients were treated with enucleation and irradiation.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Abramson DH,Ronner HJ,Ellsworth RMdoi
10.1016/0002-9394(79)90293-9subject
Has Abstractpub_date
1979-05-01 00:00:00pages
624-7issue
5eissn
0002-9394issn
1879-1891pii
0002-9394(79)90293-9journal_volume
87pub_type
杂志文章abstract：:We used specular microscopy to investigate corneal endothelial changes after excimer laser photorefractive keratectomy. Twenty patients (26 eyes) underwent photorefractive keratectomy for the correction of myopia. The central cornea endothelium of each eye was observed preoperatively and one month postoperatively. Six...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73467-1
更新日期：1993-12-15 00:00:00
abstract：:A 2,000-g infant boy had many features of the Smith-Lemli-Opitz syndrome (prenatal growth deficiency and developmental retardation, microcephaly with unusual facies, hypospadias, and feeding difficulties) as well as sclerocornea. The association of this rare eye finding with this rare congenital syndrome is unique. Su...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90327-0
更新日期：1977-07-01 00:00:00
abstract：PURPOSE:To assess the effect of verteporfin photodynamic therapy (PDT) in juxtafoveal choroidal neovascularization (CNV) secondary to pathologic myopia (PM). DESIGN:Prospective, open-label, consecutive, interventional case series. METHODS:We prospectively followed a series of 48 consecutive patients (49 eyes) with pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.11.037
更新日期：2007-03-01 00:00:00
abstract：:We investigated the influence of a racial match or mismatch between the corneal donor and recipient on the risk of endothelial rejection and subsequent graft failure in 998 corneal transplant recipients. Actuarial survival analysis showed no significant difference in the cumulative risk of endothelial rejection betwee...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90058-x
更新日期：1988-06-15 00:00:00
abstract：:We reviewed the results of vitreous surgery in 12 eyes of 12 patients with tractional macular detachment from Toxocara canis. We performed a vitrectomy and membrane peeling in all eyes, with additional scleral buckling in four eyes. After a minimum of six months' follow-up, ten of the 12 eyes (83%) had complete retina...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73253-2
更新日期：1989-07-15 00:00:00
abstract：:A microsurgical modification of the Rizzuti scleral fixation forceps for corneal and cataract surgery employs Bonn 0.12-mm teeth on an angled handle with an appropriate curve between the teeth to fix the tissue more adequately to allow accurate placement of sutures. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90077-5
更新日期：1976-12-01 00:00:00
abstract：PURPOSE:To determine the regional differences in the test-retest variability of topographic measurements of the optic nerve head obtained with a confocal scanning laser retina tomograph. METHODS:Three 10-degree topographic images centered on the optic disk of 20 individuals (20 eyes), five normal subjects, seven glauc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72656-x
更新日期：1995-10-01 00:00:00
abstract：PURPOSE:To determine if a 1-day, 1-eye trial of latanoprost 0.005% was predictive of the 1-month intraocular pressure response in patients with uncontrolled open-angle glaucoma on maximally tolerated medical therapy without latanoprost. METHODS:One eye of 39 consecutive patients was enrolled in prospective trial of la...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(01)01253-3
更新日期：2001-12-01 00:00:00
abstract：:Two patients had paresis of the trochlear nerve contralateral to the site of lesions in the brainstem. Both patients had ipsilateral blepharoptosis and miosis suggesting oculosympathetic paresis from involvement of the descending sympathetic tract, adjacent to the fourth cranial nerve nucleus and its fascicles, in the...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90818-0
更新日期：1989-01-15 00:00:00
abstract：PURPOSE:To investigate the relationship of circulating levels of soluble form of LR11 (sLR11; also called SorLA or SORL1), with the progression of proliferative diabetic retinopathy (PDR) in patients with type 2 diabetes mellitus. DESIGN:Cross-sectional study. METHODS:Fifty-four patients with type 2 diabetes mellitus...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.01.035
更新日期：2012-07-01 00:00:00
abstract：:Fifteen patients with malignant epithelial tumors of the conjunctiva were treated with beta-ray ocular applicators filled with radioactive strontium and yttrium (90Sr/90Y). Histologic examination confirmed the diagnosis. There were ten squamous cell carcinomas, four carcinomas in situ, and one case of epidermidalizati...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0002-9394(76)90731-5
更新日期：1976-02-01 00:00:00
abstract：PURPOSE:To report on the clinical manifestations, complications, and long-term visual prognosis of patients with peripheral multifocal chorioretinitis and to search for predictors for a lower visual outcome. DESIGN:Retrospective consecutive observational case series. METHODS:setting: Institutional. PATIENT POPULATIO...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.01.005
更新日期：2015-04-01 00:00:00
abstract：:During a two-year period a randomly selected age-stratified sample of subjects 65 years old and older living in Gisborne, New Zealand, was examined by an ophthalmologist to investigate visual acuity and the prevalence of the major disorders of vision in old age. A total of 481 subjects (a response rate of 86.2%) compl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90073-3
更新日期：1982-08-01 00:00:00
abstract：PURPOSE:To establish the medium-term repeatability of the iPad perimetry app Melbourne Rapid Fields (MRF) compared to Humphrey Field Analyzer (HFA) 24-2 SITA-standard and SITA-fast programs. DESIGN:Multicenter longitudinal observational clinical study. METHODS:Sixty patients (stable glaucoma/ocular hypertension/glauc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2018.03.009
更新日期：2018-06-01 00:00:00
abstract：:Fifty-five patients with primary open-angle glaucoma and early glaucomatous damage who had medical therapy and laser trabeculoplasty were followed up for four to 11 years or until progressive glaucomatous damage was documented. Factors associated with the stability or progression of glaucoma were evaluated. Eyes with ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76896-5
更新日期：1991-01-15 00:00:00
abstract：:Six patients (all male, five homosexual and one bisexual, 23 to 48 years old) with the acquired immune deficiency syndrome (AIDS) who had cytomegalovirus retinitis were treated with a new antiviral drug as a part of a prospective open-labeled trial for serious cytomegalovirus infections. The drug, 9-[2-hydroxy-1-(hydr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90638-0
更新日期：1986-04-15 00:00:00
abstract：PURPOSE:To expand our understanding of the uncommon entity, referred to as perifoveal exudative vascular anomalous complex (PEVAC) by describing multimodal imaging findings, including optical coherence tomography angiography (OCT-A). DESIGN:Retrospective cohort study. METHODS:Patients diagnosed with PEVAC were identi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2017.10.009
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:To provide current estimates of the prevalence of diagnosed dry eye disease (DED) and associated demographics among US adults aged ≥18 years. DESIGN:Cross-sectional, population-based survey. METHODS:Data were analyzed from 75 000 participants in the 2013 National Health and Wellness Survey to estimate prevale...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.06.033
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:To characterize spontaneous dislocation of the fluocinolone acetonide sustained release implant (Retisert; Bausch & Lomb) drug pellet from its strut. DESIGN:Retrospective, observational case series. METHODS:The medical records of 224 patients in whom 407 fluocinolone acetonide implants were placed by either o...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2015.01.031
更新日期：2015-05-01 00:00:00
abstract：:A 70-year-old man, a 59-year-old woman, and a 57-year-old woman underwent pars plana vitrectomy. In all three cases, cataracts developed in the eyes that had been operated on. During cataract extraction, which included massage of the globe after retrobulbar anesthesia and a conventional ab externo incision, loss of le...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90179-4
更新日期：1978-11-01 00:00:00
abstract：PURPOSE:We previously demonstrated that selective suture removal reduces keratoplasty astigmatism; however, a myopic shift was induced with the increasing number of interrupted sutures removed. This study is an attempt to determine the effects of a modified surgical technique on postkeratoplasty myopia, astigmatism, an...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)02287-0
更新日期：2003-06-01 00:00:00
abstract：PURPOSE:To report a case of persistent polymicrobial postoperative endophthalmitis caused by Alcaligenes xylosoxidans and Propionibacterium acnes in a pseudophakic eye. A. xylosoxidans is a gram-negative bacteria resistant to most antibiotics. METHODS:Case report. RESULTS:A 72-year-old man presented with clinical sig...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00405-0
更新日期：2000-06-01 00:00:00
abstract：PURPOSE:To report a rare complication, delayed suprachoroidal hemorrhage, of needle revision of a nonfunctioning trabeculectomy bleb in a patient with previously undetected hairy cell leukemia. DESIGN:Interventional case report. METHODS; An 89-year-old man presented with massive delayed suprachoroidal hemorrhage after...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00574-9
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:To identify baseline structural parameters that predict the progression of visual field (VF) loss in patients with open-angle glaucoma. DESIGN:Multicenter cohort study. METHODS:Participants from the Advanced Imaging for Glaucoma (AIG) study were enrolled and followed up. VF progression is defined as either a ...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.ajo.2016.09.015
更新日期：2016-12-01 00:00:00
abstract：:The medical records of 13 patients with primary malignant lesions of the lacrimal gland revealed adenoid cystic carcinoma as the most common malignant tumor. The histologic cell type, neural invasion, and bony destruction were correlated with localized control and ultimate survival. Surgical removal of the lacrimal gl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90455-9
更新日期：1975-01-01 00:00:00
abstract：:Severe retrobulbar hemorrhage may occur as a complication of a retrobulbar injection or from blunt or sharp injury to the orbit during an orbital or periorbital operation. When the patient with a severe retrobulbar hemorrhage does not respond to intermittent ocular massage, or paracentesis, or a lateral canthotomy, pr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71740-4
更新日期：1993-07-15 00:00:00
abstract：:As exemplified by the collaborative Diabetic Retinopathy Study, all the appropriate techniques involved in a clinical trial-random assignment of treatment, appropriate controls, and avoidance of investigator bias-should be incorporated during the earliest testing of a new therapy for a chronic disease, for the sake of...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：
更新日期：1975-04-01 00:00:00
abstract：PURPOSE:To evaluate long-term retention rates and complications of silicone punctal plugs among dry eye patients. DESIGN:Prospective, observational cohort study. METHODS:Ninety-five silicone punctal plugs (FCI plugs; FCI Ophthalmics, Issy-les-Moulineaux Cedex, France) were placed in 93 eyes of 47 dry eye patients. Wi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.05.019
更新日期：2007-09-01 00:00:00
abstract：:Simultaneous manometry and Perkins tonometry were performed at 10.0, 20.0, and 30.0 mm Hg on 15 eyes on which intraocular procedures were performed. There was a statistically significant relationship between corneal thickness and the error of Perkins tonometry. Thin corneas produced underestimations of the intraocular...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71455-2
更新日期：1993-05-15 00:00:00
abstract：PURPOSE:To evaluate the ability of pituitary adenylate cyclase-activating polypeptide (PACAP) to induce growth of neuronal processes in cultured trigeminal ganglion cells, and to accelerate neurite outgrowth and recovery of corneal sensitivity after creation of a corneal flap in a rabbit model of laser-assisted in situ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.10.034
更新日期：2007-02-01 00:00:00
