Abstract：
PURPOSE:To provide current estimates of the prevalence of diagnosed dry eye disease (DED) and associated demographics among US adults aged ≥18 years. DESIGN:Cross-sectional, population-based survey. METHODS:Data were analyzed from 75 000 participants in the 2013 National Health and Wellness Survey to estimate prevalence/risk of diagnosed DED overall, and by age, sex, insurance, and other demographic factors. We weighted the observed DED prevalence to project estimates to the US adult population and examined associations between demographic factors and DED using multivariable logistic regression. RESULTS:Based on weighted estimates, 6.8% of the US adult population was projected to have diagnosed DED (∼16.4 million people). Prevalence increased with age (18-34 years: 2.7%; ≥75 years: 18.6%) and was higher among women (8.8%; ∼11.1 million) than men (4.5%; ∼5.3 million). After adjustment, there were no substantial differences in prevalence/risk of diagnosed DED by race, education, or US census region. However, there was higher risk of diagnosed DED among those aged 45-54 years (odds ratio [OR]: 1.95; 95% confidence interval [CI]: 1.74-2.20) and ≥75 years (OR: 4.95; 95% CI: 4.26-5.74), vs those aged 18-34 years. Risk was also higher among women vs men (OR: 2.00; 95% CI: 1.88-2.13) and insured vs uninsured participants (OR: 2.12; 95% CI: 1.85-2.43 for those on government and private insurance vs none). CONCLUSIONS:We estimate that >16 million US adults have diagnosed DED. Prevalence is higher among women than men, increases with age, and is notable among those aged 18-34 years.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Farrand KF,Fridman M,Stillman IÖ,Schaumberg DAdoi
10.1016/j.ajo.2017.06.033subject
Has Abstractpub_date
2017-10-01 00:00:00pages
90-98eissn
0002-9394issn
1879-1891pii
S0002-9394(17)30290-8journal_volume
182pub_type
杂志文章abstract：PURPOSE:To determine whether a machine learning technique called Kalman filtering (KF) can accurately forecast future values of mean deviation (MD), pattern standard deviation, and intraocular pressure for patients with normal tension glaucoma (NTG). DESIGN:Development and testing of a forecasting model for glaucoma p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2018.10.012
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:We previously demonstrated that selective suture removal reduces keratoplasty astigmatism; however, a myopic shift was induced with the increasing number of interrupted sutures removed. This study is an attempt to determine the effects of a modified surgical technique on postkeratoplasty myopia, astigmatism, an...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)02287-0
更新日期：2003-06-01 00:00:00
abstract：:In two patients, a 55-year-old man and a 49-year-old man, who had fungal keratitis initially undiagnosed by corneal scrapings the condition was successfully diagnosed by corneal biopsy. We compared corneal biopsy specimens and corneal scraping in the diagnosis of keratomycosis in rabbits with experimental bilateral fu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90821-4
更新日期：1986-03-15 00:00:00
abstract：:In four patients, we repaired leaking blebs by using a new technique of excision of the cystic bleb and replacement with free conjunctival autograft. The leaks were repaired successfully, and bleb function was maintained in all four patients. This technique should be considered when surgical management of a leaking bl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70060-1
更新日期：1994-05-15 00:00:00
abstract：PURPOSE:To treat a 30-year-old man with a ventriculoperitoneal shunt who had progressive visual loss. METHODS:The patient underwent computed tomographic and magnetic resonance imaging scans and ocular examination. RESULTS:He was diagnosed with ventriculoperitoneal shunt failure despite the lack of ventriculomegaly on...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71980-4
更新日期：1996-07-01 00:00:00
abstract：PURPOSE:To determine the efficacy of internal limiting membrane (ILM) peeling during vitrectomy for rhegmatogenous retinal detachment (RRD) regarding post-vitrectomy epiretinal membrane (ERM) development and visual outcomes. DESIGN:Retrospective, interventional, comparative case series. METHODS:Setting: Institutional...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.08.015
更新日期：2016-11-01 00:00:00
abstract：:Eight patients were treated for Pseudomonas endophthalmitis associated with the implantation of contaminated intraocular lenses. All patients showed clinical signs of infection (loss of red reflex, diminished visual acuity, and intraocular lens coagulum) and P. aeruginosa was isolated from vitreous aspirates and unuse...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90569-5
更新日期：1979-11-01 00:00:00
abstract：PURPOSE:To evaluate changes in contrast sensitivity after surgery for macula-on rhegmatogenous retinal detachment (RRD). DESIGN:Prospective, interventional, consecutive, case-control study. METHODS:This study included 84 eyes of 84 patients with unilateral macula-on RRD undergoing primary scleral buckling or vitrecto...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.05.017
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:To assess whether successful surgical intervention for intermittent exotropia, or the timing of intervention, has any effect on the development of mental illness. DESIGN:Retrospective, observational case series. METHODS:All patients (<19 years of age) diagnosed with intermittent exotropia in Olmsted County, M...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.06.008
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To correlate the anatomic features of the macula with functional parameters like location and stability of fixation in patients with neovascular age-related macular degeneration treated with intravitreal ranibizumab injections. DESIGN:Retrospective analysis. METHODS:The location and stability of fixation were...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.08.034
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:To compare the accuracy of toric intraocular lens (IOL) alignment and visual outcomes using femtosecond laser-assisted capsulotomy marking (CM) versus conventional slit lamp-assisted manual marking (MM). DESIGN:Prospective cohort study. METHODS:A total of 57 patients who required cataract surgery and toric IO...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.08.041
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:To evaluate clinically the efficacy of 3600 minimally invasive endoscopic surgery in patients with orbital intraconal tumors. DESIGN:Retrospective interventional case series. METHODS:A series of consecutive patients with orbital intraconal tumors were treated by minimally invasive surgery using an endonasal e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.07.035
更新日期：2020-07-29 00:00:00
abstract：:We reviewed the long-term follow-up on a consecutive series of 16 eyes from ten patients with juvenile rheumatoid arthritis-associated cataracts that were removed by using pars plana lensectomy and vitrectomy. All patients had prominent cataracts, chronic uveitis, posterior synechiae, and vitreitis preoperatively, and...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74049-8
更新日期：1992-12-15 00:00:00
abstract：PURPOSE:To identify any temporal trends in the diagnosis of plus disease in retinopathy of prematurity (ROP) by experts. DESIGN:Reliability analysis. METHODS:ROP experts were recruited in 2007 and 2016 to classify 34 wide-field fundus images of ROP as plus, pre-plus, or normal, coded as "3," "2," and "1," respectivel...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2016.12.025
更新日期：2017-04-01 00:00:00
abstract：:Two patients had ocular myasthenia gravis coexistent with Hashimoto's thyroiditis. A 37-year-old woman presented with diplopia and displayed a head tremor and thyroid enlargement. Thyroid function tests showed an elevated thyroid stimulating hormone (TSH). A quantitative Tensilon test yeilded a "perverse" response and...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90691-1
更新日期：1975-06-01 00:00:00
abstract：PURPOSE:To determine the effectiveness of intravitreal triamcinolone acetonide in the management of bacterial endophthalmitis. DESIGN:Interventional case series. METHODS:This pilot case series included five patients (three patients after trauma and two patients after cataract surgery) with culture proven bacterial en...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.11.043
更新日期：2006-05-01 00:00:00
abstract：PURPOSE:To describe a group of patients with dense visual field defects following macular hole surgery. METHODS:Nine (7%) of 125 patients reviewed noted onset of dense visual field defects following uncomplicated vitrectomy with gas-fluid exchange for the treatment of macular hole. Patient records were reviewed to inv...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72064-1
更新日期：1996-09-01 00:00:00
abstract：PURPOSE:To report visual outcomes after peeling of the internal limiting membrane (ILM) using a brief application of low dose indocyanine green (ICG) for macular hole repair. DESIGN:Prospective, nonrandomized interventional case series. METHODS:A consecutive series of 16 eyes of 14 patients with full-thickness macula...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.06.029
更新日期：2004-11-01 00:00:00
abstract：PURPOSE:To describe the clinical and histopathologic findings in a patient with Parinaud's oculoglandular syndrome attributable to Francisella tularensis obtained from an encounter with a wild baby rabbit. METHODS:In an 18-year-old man, the clinical course, laboratory findings, and histopathologic findings are describ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00954-5
更新日期：2001-02-01 00:00:00
abstract：PURPOSE:To report a Serratia marcescens infection that clinically simulated a conjunctival neoplasm. METHOD:Case report. RESULTS:A healthy 80-year-old man without contact lenses presented with a pink-yellow conjunctival mass that resembled a solid neoplasm. Stains and cultures of material that exuded from the mass du...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00422-5
更新日期：2000-02-01 00:00:00
abstract：:We measured skin reactions serum antibody, and lymphocyte stimulation to Histoplasma antigens in a series of patients with presumed ocular histoplasmosis syndrome and in controls. The most sensitive test, lymphocyte stimulation to H. capsulatum sonicate, also correlated with severity of the disease. Lymphocyte stimula...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90069-2
更新日期：1979-03-01 00:00:00
abstract：:A 50-year-old man who had been taking betamethasone for 20 days experienced a slight bilateral decrease in visual acuity. There were localized dark-gray atrophic lesions at the posterior pole, accompanied by a diffuse detachment of the sensory retina. The retinal vessels appeared to be normal and only minimal anterior...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90526-8
更新日期：1982-03-01 00:00:00
abstract：:We reviewed the histories of three patients with sebaceous carcinoma (two of the eyelid and one of the caruncle) who had had their tumors excised by surgeons experienced in the Mohs' technique. In each patient the tumor was considered totally excised. In one patient, residual intraepithelial pagetoid sebaceous carcino...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74400-9
更新日期：1987-06-15 00:00:00
abstract：PURPOSE:To determine whether retinal arteriolar wall signs are associated with early age-related macular degeneration (AMD). DESIGN:Population-based cross-sectional study. METHODS:The Singapore Malay Eye Study (SiMES) is a population-based eye survey including 3,280 (78.7% response) persons aged 40 to 80 years. Retin...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.01.012
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:To describe the clinical characteristics and course of optic disk edema (ODE) associated with isolated sudden-onset anterior uveitis. DESIGN:Interventional, noncomparative retrospective case series. METHODS:Review of patients with sudden-onset anterior uveitis and concomitant ODE seen in an academic uveitis r...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.03.062
更新日期：2005-10-01 00:00:00
abstract：:The pathogenesis of reversible cupping of the optic disk in congenital glaucoma was examined by two approaches. Human fetal, neonatal, and adult eyes were examined by histochemistry and electron microscopy to delineate the embryologic development of the optic nerve head. While the neural, glial, and vascular elements ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90680-8
更新日期：1977-09-01 00:00:00
abstract：PURPOSE:To determine the prevalence of artifacts on segmented spectral-domain optical coherence tomography (SDOCT) images and assess their impact on the interpretation of glaucomatous progression in the retinal nerve fiber layer (RNFL) profile and macular thickness map. DESIGN:Retrospective reliability analysis. METH...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.08.018
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:To correlate in vivo imaging to histology in an eye with macular atrophy owing to age-related macular degeneration (AMD; complete retinal pigment epithelium [RPE] and outer retinal atrophy [cRORA]) to evaluate the utility of new optical coherence tomography (OCT) suggested by previous histology. DESIGN:Case st...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.06.020
更新日期：2018-09-01 00:00:00
abstract：:Presumed accidental corneal exposure to Hibiclens (chlorhexidine 4% and detergent) in two patients resulted in severe and permanent corneal opacification. We investigated the corneal toxicity of Hibiclens by gross, biomicroscopic, and histopathologic studies of rabbit eyes exposed to Hibiclens for varying time interva...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(87)90292-3
更新日期：1987-07-15 00:00:00
abstract：:A controlled chemotherapy trial of trachoma was carried out in a Tunisian oasis among schoolchildren with active disease. We compared 1% tetracycline ointment (79 patients) or 1% rifampicin ointment (76 patients) with 5% boric acid ointment (79 patients). Medications were administered twice daily, six days a week, for...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/0002-9394(75)90740-0
更新日期：1975-05-01 00:00:00
